Location: Menlo Park, CA
CIK: 0001631134 · Show all filings
Period: Q2 2021 (← Previous) (Next →)
Filing Date: Aug 16, 2021
Total Value: $1.735B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| NTRA | Natera | 3,100,560 | $352M | 20.3% | $113.53 * | $9.81 | +942.9% | COMM | 632307104 |
| — | Karuna Therapeutics, Inc. | 1,952,441 | $223M | 12.8% | $113.99 | $26.41 | — | COMM | 48576A100 |
| — | Aerovate Therapeutics, Inc. | 3,758,686 | $85.81M | 4.9% | $22.83 | $22.83 | — | COMM | 008064107 |
| — | Y-mAbs Therapeutics, Inc | 2,194,278 | $74.17M | 4.3% | $33.80 | $26.75 | — | COMM | 984241109 |
| ASND | Ascendis Pharma A/S | 521,923 | $68.66M | 4.0% | $131.55 | $69.98 | — | ADR | 04351P101 |
| AZN | AstraZeneca PLC | 959,632 | $57.48M | 3.3% | $59.90 | $49.94 | — | ADR | 046353108 |
| — | iShares TR | 325,000 | $53.19M | 3.1% | $163.65 | — | — | Put | 464287956 |
| — | Bolt Biotherapeutics, Inc. | 2,754,437 | $42.58M | 2.5% | $15.46 | $32.91 | — | COMM | 097702104 |
| UTHR | United Therapeutics Corp | 216,085 | $38.77M | 2.2% | $179.41 * | $94.24 | +102.1% | COMM | 91307C102 |
| VERA | Vera Therapeutics, Inc. | 2,914,776 | $38.65M | 2.2% | $13.26 * | $15.54 | 0.0% | CL A | 92337R101 |
| BIIB | Biogen Inc | 110,600 | $38.3M | 2.2% | $346.27 * | $302.94 | 0.0% | COMM | 09062X103 |
| — | Inozyme Pharma, Inc. | 2,028,308 | $34.56M | 2.0% | $17.04 | $26.29 | — | COMM | 45790W108 |
| GRTX | Galera Therapeutics, Inc | 3,083,712 | $30.31M | 1.7% | $9.83 * | $12.19 | -33.4% | COMM | 36338D108 |
| — | Acceleron Pharma Inc | 233,638 | $29.32M | 1.7% | $125.49 | $121.00 | — | COMM | 00434H108 |
| ALGN | Align Technology Inc | 47,093 | $28.77M | 1.7% | $611.00 * | $554.11 | +6.8% | COMM | 016255101 |
| PTCT | PTC Therapeutics Inc | 581,940 | $24.6M | 1.4% | $42.27 | $47.53 | -9.8% | COMM | 69366J200 |
| INSM | Insmed Inc | 844,169 | $24.02M | 1.4% | $28.46 * | $31.01 | -4.3% | COMM | 457669307 |
| SRPT | Sarepta Therapeutics, Inc. | 298,500 | $23.2M | 1.3% | $77.74 * | $75.81 | 0.0% | COMM | 803607100 |
| — | ARK ETF TR | 250,000 | $23.13M | 1.3% | $92.50 | — | — | Put | 00214Q952 |
| HRTX | Heron Therapeutics Inc | 1,467,675 | $22.78M | 1.3% | $15.52 * | $15.91 | 0.0% | COMM | 427746102 |
| — | Checkmate Pharmaceuticals Inc | 3,606,707 | $21.5M | 1.2% | $5.96 | $11.51 | — | COMM | 162818108 |
| — | Nextcure, Inc | 2,671,856 | $21.45M | 1.2% | $8.03 | $10.01 | — | COMM | 65343E108 |
| PTGX | Protagonist Therapeutics Inc | 449,082 | $20.16M | 1.2% | $44.88 * | $25.31 | +30.4% | COMM | 74366E102 |
| NBIX | Neurocrine Biosciences, Inc. | 203,200 | $19.77M | 1.1% | $97.32 | $95.85 | 0.0% | COMM | 64125C109 |
| EXEL | Exelixis Inc | 1,079,681 | $19.67M | 1.1% | $18.22 * | $22.75 | +2.5% | COMM | 30161Q104 |
| — | Akouos, Inc | 1,515,074 | $19.01M | 1.1% | $12.55 | $22.50 | — | COMM | 00973J101 |
| PODD | Insulet Corp | 68,500 | $18.8M | 1.1% | $274.51 | $270.80 | +0.4% | COMM | 45784P101 |
| VRTX | Vertex Pharmaceuticals Inc | 88,214 | $17.79M | 1.0% | $201.63 * | $214.60 | -2.5% | COMM | 92532F100 |
| RGNX | Regenxbio Inc | 427,740 | $16.62M | 1.0% | $38.85 * | $36.38 | -1.7% | COMM | 75901B107 |
| — | Nucana Biomed Ltd | 5,599,999 | $15.51M | 0.9% | $2.77 | $9.47 | — | ADR | 67022C106 |
| — | Agenus Inc | 2,769,900 | $15.21M | 0.9% | $5.49 | $2.72 | — | COMM | 00847G705 |
| DXCM | Dexcom Inc | 33,713 | $14.39M | 0.8% | $426.99 * | $94.30 | +1.8% | COMM | 252131107 |
| — | ObsEva SA | 4,749,623 | $14.39M | 0.8% | $3.03 | $13.49 | — | COMM | H5861P103 |
| — | Intra-Cellular Therapies Inc | 313,159 | $12.78M | 0.7% | $40.82 | $27.53 | — | COMM | 46116X101 |
| — | Mirati Therapeutics Inc | 78,538 | $12.69M | 0.7% | $161.53 | $171.30 | — | COMM | 60468T105 |
| AGIO | Agios Pharmaceuticals, Inc. | 219,033 | $12.07M | 0.7% | $55.11 | $55.92 | 0.0% | COMM | 00847X104 |
| — | Reata Pharmaceuticals Inc | 79,601 | $11.27M | 0.6% | $141.53 | $110.30 | — | COMM | 75615P103 |
| QURE | Uniqure NV | 324,303 | $9.989M | 0.6% | $30.80 * | $35.84 | -6.5% | COMM | N90064101 |
| AMGN | Amgen Inc | 40,500 | $9.872M | 0.6% | $243.75 * | $205.57 | +3.4% | COMM | 031162100 |
| CYTK | Cytokinetics Inc | 481,323 | $9.525M | 0.5% | $19.79 * | $20.93 | +12.2% | COMM | 23282W605 |
| KURA | Kura Oncology Inc | 444,372 | $9.265M | 0.5% | $20.85 * | $22.88 | +8.5% | COMM | 50127T109 |
| — | Nucana Biomed Ltd | 2,400,000 | $6.648M | 0.4% | $2.77 | $4.99 | — | Ordinary Shares | GB00BYWYV |
| MGNX | MacroGenics Inc | 234,504 | $6.299M | 0.4% | $26.86 * | $27.33 | +7.2% | COMM | 556099109 |
| — | ChemoCentryx Inc | 465,637 | $6.235M | 0.4% | $13.39 | $27.69 | — | COMM | 16383L106 |
| — | Marinus Pharmaceuticals Inc | 346,160 | $6.21M | 0.4% | $17.94 | $13.05 | — | COMM | 56854Q200 |
| CHRS | Coherus BioSciences | 434,555 | $6.01M | 0.3% | $13.83 * | $10.94 | +29.4% | COMM | 19249H103 |
| — | Cyteir Therapeutics, Inc. | 265,000 | $5.671M | 0.3% | $21.40 | $21.40 | — | COMM | 23284P103 |
| — | FibroGen, Inc. | 200,000 | $5.326M | 0.3% | $26.63 | — | — | Put | 31572Q958 |
| IMTX | Immatics NV | 443,370 | $5.148M | 0.3% | $11.61 | $10.88 | +7.9% | COMM | N44445109 |
| — | Amarin Corp | 1,170,584 | $5.127M | 0.3% | $4.38 | $7.81 | — | ADR | 023111206 |
| — | TCR2 Therapeutics Inc | 296,282 | $4.862M | 0.3% | $16.41 | $25.43 | — | COMM | 87808K106 |
| CLDX | Celldex Therapeutics, Inc. | 134,724 | $4.505M | 0.3% | $33.44 * | $27.45 | 0.0% | COMM | 15117B202 |
| MIRM | Mirum Pharmaceuticals Inc | 259,465 | $4.486M | 0.3% | $17.29 * | $17.49 | +2.5% | COMM | 604749101 |
| — | Jounce Therapeutics Inc | 624,756 | $4.248M | 0.2% | $6.80 | $6.96 | — | COMM | 481116101 |
| FATE | Fate Therapeutics Inc | 46,386 | $4.026M | 0.2% | $86.79 * | $80.81 | -0.3% | COMM | 31189P102 |
| — | Aligos Therapeutics Inc | 164,051 | $3.344M | 0.2% | $20.38 | $27.65 | — | COMM | 01626L105 |
| — | ChemoCentryx Inc | 215,000 | $2.879M | 0.2% | $13.39 | — | — | Call | 16383L906 |
| — | Otonomy Inc | 1,251,256 | $2.79M | 0.2% | $2.23 | $3.81 | — | COMM | 68906L105 |
| REPL | Replimune Group Inc | 71,661 | $2.753M | 0.2% | $38.42 * | $38.04 | -10.1% | COMM | 76029N106 |
| BCRX | BioCryst Pharmaceuticals Inc | 158,609 | $2.508M | 0.1% | $15.81 * | $4.01 | +238.6% | COMM | 09058V103 |
| — | ACADIA Pharmaceuticals Inc | 100,000 | $2.439M | 0.1% | $24.39 | — | — | Call | 004225908 |
| — | TCR2 Therapeutics Inc | 139,700 | $2.292M | 0.1% | $16.41 | — | — | Put | 87808K956 |
| — | Synlogic Inc. | 574,972 | $2.237M | 0.1% | $3.89 | $9.38 | — | COMM | 87166L100 |
| SVRA | Savara Inc | 1,278,424 | $2.173M | 0.1% | $1.70 * | $1.71 | +5.1% | COMM | 805111101 |
| PDSB | PDS Biotechnology Corporation | 142,635 | $1.79M | 0.1% | $12.55 * | $8.36 | -6.6% | COMM | 70465T107 |
| — | CTI BioPharma Corp | 171,619 | $429K | 0.0% | $2.50 | $2.50 | — | COMM | 12648L601 |
| — | Sierra Oncology, Inc. | 2,500 | $49,000 | 0.0% | $19.60 | $19.60 | — | COMM | 82640U404 |