Location: Menlo Park, CA
CIK: 0001631134 · Show all filings
Period: Q4 2021 (← Previous) (Next →)
Filing Date: Feb 14, 2022
Total Value: $1.712B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| NTRA | Natera Inc | 3,102,960 | $290M | 16.9% | $93.39 * | $9.81 | +958.0% | COMM | 632307104 |
| — | Karuna Therapeutics, Inc. | 1,953,077 | $256M | 14.9% | $131.00 | $26.41 | — | COMM | 48576A100 |
| VERA | Vera Therapeutics, Inc. | 2,914,776 | $77.88M | 4.5% | $26.72 * | $15.54 | +42.3% | CL A | 92337R101 |
| RHHBY | Roche Holding AG | 1,369,011 | $70.76M | 4.1% | $51.69 | $51.69 | — | ADR | 771195104 |
| ASND | Ascendis Pharma A/S | 499,824 | $67.24M | 3.9% | $134.53 | $69.98 | — | ADR | 04351P101 |
| SPY | SPDR S&P 500 ETF Trust | 100,000 | $47.5M | 2.8% | $474.96 | — | — | Put | 78462F103 |
| — | Aerovate Therapeutics, Inc. | 3,758,686 | $44.31M | 2.6% | $11.79 | $22.83 | — | COMM | 008064107 |
| ABBV | Abbvie Inc | 312,018 | $42.25M | 2.5% | $135.40 * | $97.79 | +4.0% | COMM | 00287Y109 |
| QQQ | Invesco QQQ Trust Series 1 | 100,000 | $39.78M | 2.3% | $397.85 | — | — | Put | 46090E103 |
| — | Y-mAbs Therapeutics, Inc | 2,194,278 | $35.57M | 2.1% | $16.21 | $26.75 | — | COMM | 984241109 |
| IWM | iShares Russell 2000 ETF | 150,000 | $33.37M | 1.9% | $222.45 | — | — | Put | 464287655 |
| RGNX | Regenxbio Inc | 1,008,081 | $32.96M | 1.9% | $32.70 * | $34.35 | -0.9% | COMM | 75901B107 |
| TVTX | Travere Therapeutics Inc | 1,040,858 | $32.31M | 1.9% | $31.04 * | $24.05 | +17.1% | COMM | 89422G107 |
| UTHR | United Therapeutics Corp | 129,754 | $28.04M | 1.6% | $216.08 * | $97.02 | +102.3% | COMM | 91307C102 |
| HRTX | Heron Therapeutics Inc | 2,933,351 | $26.78M | 1.6% | $9.13 * | $13.62 | -25.0% | COMM | 427746102 |
| — | ChemoCentryx Inc | 731,222 | $26.62M | 1.6% | $36.41 | $29.48 | — | COMM | 16383L106 |
| — | Blueprint Medicines Corp | 245,182 | $26.26M | 1.5% | $107.11 | $103.92 | — | COMM | 09627Y109 |
| ALGN | Align Technology Inc | 38,159 | $25.08M | 1.5% | $657.17 * | $554.11 | +16.0% | COMM | 016255101 |
| — | Horizon Therapeutics PLC | 221,792 | $23.9M | 1.4% | $107.76 | $109.02 | — | COMM | G46188101 |
| GH | Guardant Health Inc | 232,563 | $23.26M | 1.4% | $100.02 * | $106.07 | -2.5% | COMM | 40131M109 |
| XNCR | Xencor Inc | 537,030 | $21.55M | 1.3% | $40.12 * | $37.91 | 0.0% | COMM | 98401F105 |
| CYTK | Cytokinetics Inc | 464,366 | $21.17M | 1.2% | $45.58 * | $22.36 | +72.5% | COMM | 23282W605 |
| BCRX | BioCryst Pharmaceuticals Inc | 1,510,473 | $20.92M | 1.2% | $13.85 * | $13.23 | 0.0% | COMM | 09058V103 |
| SNDX | Syndax Pharmaceuticals Inc | 951,226 | $20.82M | 1.2% | $21.89 * | $17.69 | +4.5% | COMM | 87164F105 |
| IRTC | iRhythm Technologies Inc | 168,882 | $19.88M | 1.2% | $117.69 * | $91.74 | 0.0% | COMM | 450056106 |
| DXCM | Dexcom Inc | 32,404 | $17.4M | 1.0% | $536.94 * | $97.33 | +47.6% | COMM | 252131107 |
| PTGX | Protagonist Therapeutics Inc | 482,257 | $16.49M | 1.0% | $34.20 * | $27.72 | +14.0% | COMM | 74366E102 |
| — | Inhibrx Inc | 368,679 | $16.1M | 0.9% | $43.67 | $43.67 | — | COMM | 45720L107 |
| — | Nextcure, Inc | 2,671,856 | $16.03M | 0.9% | $6.00 | $10.01 | — | COMM | 65343E108 |
| GRTX | Galera Therapeutics, Inc | 3,083,712 | $14.15M | 0.8% | $4.59 * | $12.19 | -72.9% | COMM | 36338D108 |
| — | Inozyme Pharma, Inc. | 2,028,308 | $13.83M | 0.8% | $6.82 | $26.29 | — | COMM | 45790W108 |
| IMTX | Immatics NV | 1,026,623 | $13.8M | 0.8% | $13.44 * | $11.81 | +5.8% | COMM | N44445109 |
| — | Bolt Biotherapeutics, Inc. | 2,754,437 | $13.5M | 0.8% | $4.90 | $32.91 | — | COMM | 097702104 |
| — | Iveric Bio Inc | 798,789 | $13.36M | 0.8% | $16.72 | $16.51 | — | COMM | 46583P102 |
| — | Nucana Plc | 5,599,999 | $13.33M | 0.8% | $2.38 | $9.47 | — | ADR | 67022C106 |
| — | Jounce Therapeutics Inc | 1,582,777 | $13.22M | 0.8% | $8.35 | $7.80 | — | COMM | 481116101 |
| — | ImmunoGen Inc | 1,749,882 | $12.98M | 0.8% | $7.42 | $7.42 | — | COMM | 45253H101 |
| — | Akouos, Inc. | 1,515,074 | $12.88M | 0.8% | $8.50 | $22.50 | — | COMM | 00973J101 |
| INSM | Insmed Inc | 441,773 | $12.03M | 0.7% | $27.24 * | $31.01 | -7.8% | COMM | 457669307 |
| FULC | Fulcrum Therapeutics Inc | 617,670 | $10.93M | 0.6% | $17.69 * | $19.74 | +0.4% | COMM | 359616109 |
| SRPT | Sarepta Therapeutics Inc | 120,732 | $10.87M | 0.6% | $90.05 * | $75.81 | +12.8% | COMM | 803607100 |
| CLDX | Celldex Therapeutics Inc | 271,533 | $10.49M | 0.6% | $38.64 * | $35.60 | +22.4% | COMM | 15117B202 |
| — | Checkmate Pharmaceuticals Inc | 3,606,707 | $10.35M | 0.6% | $2.87 | $11.51 | — | COMM | 162818108 |
| PTGX | Protagonist Therapeutics Inc | 300,600 | $10.28M | 0.6% | $34.20 * | $27.72 | +14.0% | Call | 74366E102 |
| QURE | Uniqure NV | 495,025 | $10.27M | 0.6% | $20.74 * | $29.82 | -3.8% | COMM | N90064101 |
| — | ObsEva SA | 4,749,623 | $9.452M | 0.6% | $1.99 | $13.49 | — | COMM | H5861P103 |
| VIR | Vir Biotechnology Inc | 200,000 | $8.374M | 0.5% | $41.87 | — | — | Put | 92764N102 |
| BMRN | Biomarin Pharmaceutical Inc | 87,322 | $7.715M | 0.5% | $88.35 * | $82.51 | 0.0% | COMM | 09061G101 |
| — | Zymeworks Inc | 392,712 | $6.437M | 0.4% | $16.39 | $29.04 | — | COMM | 98985W102 |
| — | Agenus Inc | 1,961,032 | $6.315M | 0.4% | $3.22 | $2.72 | — | COMM | 00847G705 |
| — | Nucana Plc | 2,400,000 | $5.712M | 0.3% | $2.38 | $4.99 | — | Ordinary Shares | GB00BYWYV |
| IFRX | Inflarx NV | 1,161,736 | $5.53M | 0.3% | $4.76 * | $4.02 | 0.0% | COMM | N44821101 |
| — | Adicet Bio Inc | 310,988 | $5.439M | 0.3% | $17.49 | $17.49 | — | COMM | 007002108 |
| PTCT | PTC Therapeutics Inc | 132,448 | $5.275M | 0.3% | $39.83 * | $47.53 | -19.5% | COMM | 69366J200 |
| KURA | Kura Oncology Inc | 369,173 | $5.168M | 0.3% | $14.00 * | $21.22 | -23.6% | COMM | 50127T109 |
| — | Sierra Oncology Inc | 212,281 | $4.615M | 0.3% | $21.74 | $21.89 | — | COMM | 82640U404 |
| AXSM | Axsome Therapeutics Inc | 100,000 | $3.778M | 0.2% | $37.78 | — | — | Put | 05464T104 |
| NVCR | Novocure Ltd | 50,000 | $3.754M | 0.2% | $75.08 | — | — | Call | G6674U108 |
| — | Intra-Cellular Therapies Inc | 56,915 | $2.979M | 0.2% | $52.34 | $27.53 | — | COMM | 46116X101 |
| KURA | Kura Oncology Inc | 175,000 | $2.45M | 0.1% | $14.00 * | $21.22 | -23.6% | Call | 50127T109 |
| — | Intercept Pharmaceuticals Inc | 150,400 | $2.45M | 0.1% | $16.29 | — | — | Call | 45845P108 |
| — | Cyteir Therapeutics Inc | 179,450 | $2.04M | 0.1% | $11.37 | $21.40 | — | COMM | 23284P103 |
| — | Marinus Pharmaceuticals Inc | 171,338 | $2.035M | 0.1% | $11.88 | $13.02 | — | COMM | 56854Q200 |
| — | Mink Therapeutics Inc | 345,499 | $1.541M | 0.1% | $4.46 | $4.46 | — | COMM | 603693102 |
| — | Aligos Therapeutics Inc | 127,791 | $1.517M | 0.1% | $11.87 | $27.22 | — | COMM | 01626L105 |
| — | Synlogic Inc. | 574,972 | $1.391M | 0.1% | $2.42 | $9.38 | — | COMM | 87166L100 |
| PDSB | PDS Biotechnology Corporation | 142,635 | $1.155M | 0.1% | $8.10 * | $8.36 | +28.7% | COMM | 70465T107 |
| — | Fusion Pharmaceuticals Inc | 78,066 | $326K | 0.0% | $4.18 | $7.92 | — | COMM | 36118A100 |
| PODD | Insulet Corp | 1,066 | $284K | 0.0% | $266.42 * | $270.80 | +7.1% | COMM | 45784P101 |
| EW | Edwards Lifesciences Corp | 1,406 | $182K | 0.0% | $129.45 * | $116.64 | 0.0% | COMM | 28176E108 |