Location: Menlo Park, CA
CIK: 0001631134 · Show all filings
Period: Q1 2022 (← Previous) (Next →)
Filing Date: May 16, 2022
Total Value: $1.318B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | Karuna Therapeutics, Inc. | 1,953,077 | $248M | 18.8% | $126.79 | $26.41 | — | COMM | 48576A100 |
| NTRA | Natera Inc | 3,102,960 | $126M | 9.6% | $40.68 * | $9.81 | +512.6% | COMM | 632307104 |
| — | Cincor Pharma, Inc. | 5,573,949 | $97.77M | 7.4% | $17.54 | $17.54 | — | COMM | 17240Y109 |
| VERA | Vera Therapeutics, Inc. | 3,181,442 | $74.73M | 5.7% | $23.49 * | $16.04 | +34.1% | CL A | 92337R101 |
| — | Aerovate Therapeutics, Inc. | 3,758,686 | $68.9M | 5.2% | $18.33 | $22.83 | — | COMM | 008064107 |
| QQQ | Invesco QQQ Trust Series 1 | 175,000 | $63.45M | 4.8% | $362.54 | — | — | Put | 46090E103 |
| ASND | Ascendis Pharma A/S | 499,824 | $58.66M | 4.5% | $117.36 | $69.98 | — | ADR | 04351P101 |
| AZN | AstraZeneca PLC | 553,903 | $36.75M | 2.8% | $66.34 | $66.34 | — | ADR | 046353108 |
| UTHR | United Therapeutics Corp | 199,183 | $35.73M | 2.7% | $179.41 * | $129.60 | +47.0% | COMM | 91307C102 |
| IWM | iShares Russell 2000 ETF | 150,000 | $30.79M | 2.3% | $205.27 | — | — | Put | 464287655 |
| — | Y-mAbs Therapeutics, Inc | 2,194,278 | $26.07M | 2.0% | $11.88 | $26.75 | — | COMM | 984241109 |
| VRTX | Vertex Pharmaceuticals Inc | 95,003 | $24.79M | 1.9% | $260.97 * | $237.33 | 0.0% | COMM | 92532F100 |
| — | Horizon Therapeutics PLC | 232,894 | $24.5M | 1.9% | $105.21 | $108.84 | — | COMM | G46188101 |
| DXCM | Dexcom Inc | 40,265 | $20.6M | 1.6% | $511.61 * | $99.68 | +9.7% | COMM | 252131107 |
| RGNX | Regenxbio Inc | 614,085 | $20.38M | 1.5% | $33.19 * | $34.35 | -19.1% | COMM | 75901B107 |
| ZTS | Zoetis Inc | 106,574 | $20.1M | 1.5% | $188.59 | $190.28 | 0.0% | COMM | 98978V103 |
| — | Reata Pharmaceuticals Inc | 602,545 | $19.74M | 1.5% | $32.76 | $32.76 | — | COMM | 75615P103 |
| — | Sierra Oncology Inc | 572,297 | $18.34M | 1.4% | $32.05 | $28.28 | — | COMM | 82640U404 |
| XBI | Spdr S&P Biotech Etf | 200,000 | $17.98M | 1.4% | $89.88 | — | — | Put | 78464A870 |
| — | Iveric Bio Inc | 1,021,211 | $17.19M | 1.3% | $16.83 | $16.58 | — | COMM | 46583P102 |
| TVTX | Travere Therapeutics Inc | 658,249 | $16.96M | 1.3% | $25.77 * | $24.05 | +10.4% | COMM | 89422G107 |
| GH | Guardant Health Inc | 239,995 | $15.9M | 1.2% | $66.24 * | $104.91 | -34.8% | COMM | 40131M109 |
| — | ChemoCentryx Inc | 573,684 | $14.38M | 1.1% | $25.07 | $29.48 | — | COMM | 16383L106 |
| BMRN | Biomarin Pharmaceutical Inc | 176,533 | $13.61M | 1.0% | $77.10 * | $83.10 | +0.7% | COMM | 09061G101 |
| — | Nextcure, Inc | 2,671,856 | $12.98M | 1.0% | $4.86 | $10.01 | — | COMM | 65343E108 |
| PTGX | Protagonist Therapeutics Inc | 547,441 | $12.96M | 1.0% | $23.68 * | $27.77 | +1.4% | COMM | 74366E102 |
| SNDX | Syndax Pharmaceuticals Inc | 717,064 | $12.46M | 0.9% | $17.38 * | $17.69 | -4.8% | COMM | 87164F105 |
| — | Checkmate Pharmaceuticals Inc | 3,606,707 | $11.51M | 0.9% | $3.19 | $11.51 | — | COMM | 162818108 |
| — | Inhibrx Inc | 514,640 | $11.47M | 0.9% | $22.28 | $37.60 | — | COMM | 45720L107 |
| IMTX | Immatics NV | 1,268,063 | $10.13M | 0.8% | $7.99 * | $11.29 | -19.3% | COMM | N44445109 |
| — | Jounce Therapeutics Inc | 1,481,219 | $10.06M | 0.8% | $6.79 | $7.80 | — | COMM | 481116101 |
| — | CTI Biopharma Corp | 1,952,691 | $9.119M | 0.7% | $4.67 | $4.67 | — | COMM | 12648L601 |
| — | Adicet Bio Inc | 416,289 | $8.313M | 0.6% | $19.97 | $18.12 | — | COMM | 007002108 |
| — | Inozyme Pharma, Inc. | 2,028,308 | $8.296M | 0.6% | $4.09 | $26.29 | — | COMM | 45790W108 |
| — | Bolt Biotherapeutics, Inc. | 2,754,437 | $7.547M | 0.6% | $2.74 | $32.91 | — | COMM | 097702104 |
| — | ChemoCentryx Inc | 300,000 | $7.521M | 0.6% | $25.07 | — | — | Call | 16383L906 |
| GRTX | Galera Therapeutics, Inc | 3,083,712 | $7.339M | 0.6% | $2.38 * | $12.19 | -78.6% | COMM | 36338D108 |
| XNCR | Xencor Inc | 273,992 | $7.31M | 0.6% | $26.68 * | $37.91 | -14.9% | COMM | 98401F105 |
| — | Akouos, Inc. | 1,515,074 | $7.197M | 0.5% | $4.75 | $22.50 | — | COMM | 00973J101 |
| BCYC | Bicycle Therapeutics PLC | 163,559 | $7.177M | 0.5% | $43.88 | $43.88 | — | ADR | 088786108 |
| — | ObsEva SA | 4,749,623 | $7.172M | 0.5% | $1.51 | $13.49 | — | COMM | H5861P103 |
| SRPT | Sarepta Therapeutics Inc | 88,880 | $6.943M | 0.5% | $78.12 | $75.81 | +1.0% | COMM | 803607100 |
| — | ImmunoGen Inc | 1,428,169 | $6.798M | 0.5% | $4.76 | $7.42 | — | COMM | 45253H101 |
| — | Nucana Plc | 5,599,999 | $5.594M | 0.4% | $1.00 | $9.47 | — | ADR | 67022C106 |
| FULC | Fulcrum Therapeutics Inc | 229,509 | $5.428M | 0.4% | $23.65 * | $19.74 | -28.3% | COMM | 359616109 |
| PTGX | Protagonist Therapeutics Inc | 200,000 | $4.736M | 0.4% | $23.68 * | $27.77 | +1.4% | Call | 74366E102 |
| GERN | Geron Corp | 1,904,762 | $2.59M | 0.2% | $1.36 * | $1.11 | 0.0% | COMM | 374163103 |
| PFE | Pfizer Inc | 49,378 | $2.556M | 0.2% | $51.76 * | $42.47 | 0.0% | COMM | 717081103 |
| — | Nucana Plc | 2,400,000 | $2.398M | 0.2% | $1.00 | $4.99 | — | Ordinary Shares | GB00BYWYV |
| CYTK | Cytokinetics Inc | 62,944 | $2.317M | 0.2% | $36.81 * | $22.36 | +58.9% | COMM | 23282W605 |
| — | Intercept Pharmaceuticals Inc | 100,000 | $1.627M | 0.1% | $16.27 | — | — | Call | 45845P108 |
| — | Synlogic Inc. | 574,972 | $1.38M | 0.1% | $2.40 | $9.38 | — | COMM | 87166L100 |
| GERN | Geron Corp | 1,000,000 | $1.36M | 0.1% | $1.36 * | $1.11 | 0.0% | Call | 374163103 |
| AMLX | Amylyx Pharmaceuticals Inc | 100,000 | $1.285M | 0.1% | $12.85 * | $22.45 | 0.0% | COMM | 03237H101 |
| PDSB | PDS Biotechnology Corporation | 142,635 | $883K | 0.1% | $6.19 | $8.36 | -25.7% | COMM | 70465T107 |
| — | Mink Therapeutics Inc | 331,002 | $745K | 0.1% | $2.25 | $4.46 | — | COMM | 603693102 |
| — | Fusion Pharmaceuticals Inc | 78,066 | $607K | 0.0% | $7.78 | $7.92 | — | COMM | 36118A100 |
| PODD | Insulet Corp | 1,066 | $284K | 0.0% | $266.42 * | $270.80 | -9.4% | COMM | 45784P101 |
| PTCT | PTC Therapeutics Inc | 3,480 | $130K | 0.0% | $37.36 * | $47.53 | -18.9% | COMM | 69366J200 |
| INSM | Insmed Inc | 5,368 | $126K | 0.0% | $23.47 | $31.01 | -25.1% | COMM | 457669307 |
| HRTX | Heron Therapeutics Inc | 11,060 | $63,000 | 0.0% | $5.70 * | $13.62 | -46.3% | COMM | 427746102 |