5AM Venture Management, LLC Long-Term Concentrated

Location: San Francisco, CA

CIK: 0001799883 · Show all filings

Period: Q4 2022 (← Previous) (Next →)

Filing Date: Feb 14, 2023

Total Value: $372M (100.0% shares, 0.0% debt)

Holdings (21)

— CINCOR PHARMA INC 16.3%

Value $60.68M Shares 4,937,646 Est. Cost $19.40 Unrealized —

TRDA ENTRADA THERAPEUTICS INC 16.0%

Value $59.6M Shares 4,408,379 Est. Cost $17.12 Unrealized —

— VOR BIOPHARMA INC 11.4%

Value $42.31M Shares 6,361,723 Est. Cost $43.10 Unrealized —

— RALLYBIO CORP 6.6%

Value $24.51M Shares 3,730,724 Est. Cost $17.58 Unrealized —

IDYA IDEAYA BIOSCIENCES INC 5.8%

Value $21.74M Shares 1,196,298 Est. Cost $7.13 Unrealized +135.8%

— PEAR THERAPEUTICS INC 5.3%

Value $19.76M Shares 16,744,113 Est. Cost $6.20 Unrealized —

— SCPHARMACEUTICALS INC 5.3%

Value $19.61M Shares 2,734,852 Est. Cost $5.92 Unrealized —

CRNX CRINETICS PHARMACEUTICALS IN 4.2%

Value $15.78M Shares 862,286 Est. Cost $19.04 Unrealized -7.4%

RNAM AVIDITY BIOSCIENCES INC 4.0%

Value $14.77M Shares 665,555 Est. Cost $18.92 Unrealized -21.2%

IRON DISC MEDICINE INC 3.1%

Value $11.7M Shares 588,442 Est. Cost $49.79 Unrealized 0.0%

ANAB ANAPTYSBIO INC 3.0%

Value $11.09M Shares 357,733 Est. Cost $28.24 Unrealized 0.0%

ARVN ARVINAS INC 2.9%

Value $10.95M Shares 320,000 Est. Cost $29.28 Unrealized +43.7%

— IMPEL NEUROPHARMA INC 2.9%

Value $10.82M Shares 2,884,791 Est. Cost $8.85 Unrealized —

COGT COGENT BIOSCIENCES INC 2.5%

Value $9.137M Shares 790,440 Est. Cost $6.91 Unrealized +79.3%

VRDN VIRIDIAN THERAPEUTICS INC 2.4%

Value $8.763M Shares 300,000 Est. Cost $17.98 Unrealized +28.2%

— IVERIC BIO INC 2.2%

Value $8.235M Shares 384,626 Est. Cost $16.46 Unrealized —

PHVS PHARVARIS N V 1.8%

Value $6.611M Shares 587,600 Est. Cost $18.63 Unrealized -71.8%

JANX JANUX THERAPEUTICS INC 1.6%

Value $5.877M Shares 446,266 Est. Cost $22.27 Unrealized -34.3%

— HOMOLOGY MEDICINES INC 1.5%

Value $5.715M Shares 4,535,919 Est. Cost $20.70 Unrealized —

— FIBROGEN INC 1.0%

Value $3.614M Shares 225,583 Est. Cost $16.02 Unrealized —

— CIDARA THERAPEUTICS INC 0.2%

Value $858K Shares 1,134,511 Est. Cost $3.84 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	CINCOR PHARMA INC	4,937,646	$60.68M	16.3%	$19.40	—	COM	17240Y109
TRDA	ENTRADA THERAPEUTICS INC	4,408,379	$59.6M	16.0%	$17.12	—	COM	29384C108
—	VOR BIOPHARMA INC	6,361,723	$42.31M	11.4%	$43.10	—	COM	929033108
—	RALLYBIO CORP	3,730,724	$24.51M	6.6%	$17.58	—	COM	75120L100
IDYA	IDEAYA BIOSCIENCES INC	1,196,298	$21.74M	5.8%	$7.13	+135.8%	COM	45166A102
—	PEAR THERAPEUTICS INC	16,744,113	$19.76M	5.3%	$6.20	—	CLASS A COM	704723105
—	SCPHARMACEUTICALS INC	2,734,852	$19.61M	5.3%	$5.92	—	COM	810648105
CRNX	CRINETICS PHARMACEUTICALS IN	862,286	$15.78M	4.2%	$19.04	-7.4%	COM	22663K107
RNAM	AVIDITY BIOSCIENCES INC	665,555	$14.77M	4.0%	$18.92	-21.2%	COM	05370A108
IRON	DISC MEDICINE INC	588,442	$11.7M	3.1%	$49.79	0.0%	COM	254604101
ANAB	ANAPTYSBIO INC	357,733	$11.09M	3.0%	$28.24	0.0%	COM	032724106
ARVN	ARVINAS INC	320,000	$10.95M	2.9%	$29.28	+43.7%	COM	04335A105
—	IMPEL NEUROPHARMA INC	2,884,791	$10.82M	2.9%	$8.85	—	COM	45258K109
COGT	COGENT BIOSCIENCES INC	790,440	$9.137M	2.5%	$6.91	+79.3%	COM	19240Q201
VRDN	VIRIDIAN THERAPEUTICS INC	300,000	$8.763M	2.4%	$17.98	+28.2%	COM	92790C104
—	IVERIC BIO INC	384,626	$8.235M	2.2%	$16.46	—	COM	46583P102
PHVS	PHARVARIS N V	587,600	$6.611M	1.8%	$18.63	-71.8%	COM	N69605108
JANX	JANUX THERAPEUTICS INC	446,266	$5.877M	1.6%	$22.27	-34.3%	COM	47103J105
—	HOMOLOGY MEDICINES INC	4,535,919	$5.715M	1.5%	$20.70	—	COM	438083107
—	FIBROGEN INC	225,583	$3.614M	1.0%	$16.02	—	COM	31572Q808
—	CIDARA THERAPEUTICS INC	1,134,511	$858K	0.2%	$3.84	—	COM	171757107