Sofinnova Investments, Inc. Quant / Systematic

Location: Menlo Park, CA

CIK: 0001631134 · Show all filings

Period: Q2 2025 (← Previous) (Next →)

Filing Date: Aug 14, 2025

Total Value: $1.635B (100.0% shares, 0.0% debt)

Holdings (63)

NTRA Natera Inc 16.0%
Value $262M Shares 1,550,280 Est. Cost $9.81 Unrealized +1488.7%
GILD Gilead Sciences Inc 7.1%
Value $116M Shares 1,050,308 Est. Cost $97.45 Unrealized +7.1%
LLY Eli Lilly and Co 4.6%
Value $75.63M Shares 97,018 Est. Cost $801.58 Unrealized -3.5%
JAZZ Jazz Pharmaceuticals PLC 4.5%
Value $73.66M Shares 694,096 Est. Cost $113.27 Unrealized -4.1%
VERA Vera Therapeutics Inc 4.0%
Value $65.83M Shares 2,793,987 Est. Cost $15.35 Unrealized +46.5%
IWM iShares TR 3.3%
Value $53.95M Shares 250,000 Est. Cost Unrealized
ABBV AbbVie Inc 3.0%
Value $49.35M Shares 265,850 Est. Cost $182.67 Unrealized 0.0%
IBB iShares TR 2.9%
Value $47.44M Shares 375,000 Est. Cost Unrealized
BSX Boston Scientific Corp 2.8%
Value $46.32M Shares 431,200 Est. Cost $101.18 Unrealized 0.0%
DXCM Dexcom Inc 2.8%
Value $45.71M Shares 523,694 Est. Cost $76.62 Unrealized +2.3%
IDYA IDEAYA Biosciences Inc 2.8%
Value $45.15M Shares 2,147,795 Est. Cost $25.35 Unrealized -24.3%
BBIO BridgeBio Pharma Inc 2.6%
Value $42.88M Shares 993,093 Est. Cost $34.41 Unrealized +5.7%
ISRG Intuitive Surgical Inc 2.3%
Value $38.39M Shares 70,642 Est. Cost $522.53 Unrealized +0.1%
RYTM Rhythm Pharmaceuticals Inc 2.3%
Value $37.03M Shares 586,010 Est. Cost $53.22 Unrealized +15.0%
AVBP Arrivent BioPharma Inc 2.3%
Value $36.94M Shares 1,696,752 Est. Cost $20.17 Unrealized +2.9%
ROIV Roivant Sciences Ltd 2.1%
Value $34.81M Shares 3,088,814 Est. Cost $10.83 Unrealized +0.1%
SLNO Soleno Therapeutics Inc 2.1%
Value $34.79M Shares 415,219 Est. Cost $45.28 Unrealized +65.3%
UTHR United Therapeutics Corp 2.1%
Value $34.05M Shares 118,513 Est. Cost $298.86 Unrealized 0.0%
INSM Insmed Inc 1.9%
Value $31.59M Shares 313,923 Est. Cost $51.55 Unrealized +48.3%
Akero Therapeutics Inc 1.8%
Value $29.28M Shares 548,788 Est. Cost $41.39 Unrealized
SUPN Supernus Pharmaceuticals Inc 1.5%
Value $25.19M Shares 799,253 Est. Cost $34.25 Unrealized -6.4%
ANAB AnaptysBio Inc 1.4%
Value $22.92M Shares 1,032,362 Est. Cost $17.55 Unrealized +19.3%
RAPP Rapport Therapeutics Inc 1.4%
Value $22.69M Shares 1,995,594 Est. Cost $23.12 Unrealized -54.1%
QURE Uniqure NV 1.3%
Value $21.72M Shares 1,558,356 Est. Cost $13.65 Unrealized -1.5%
Merus N V 1.3%
Value $21.28M Shares 404,562 Est. Cost $52.60 Unrealized
AZN AstraZeneca PLC 1.3%
Value $20.52M Shares 293,661 Est. Cost $69.88 Unrealized
PTCT PTC Therapeutics Inc 1.1%
Value $18.36M Shares 375,939 Est. Cost $49.90 Unrealized -4.9%
Inozyme Pharma Inc 1.0%
Value $17.12M Shares 4,280,308 Est. Cost $14.88 Unrealized
COGT Cogent Biosciences Inc 1.0%
Value $16.91M Shares 2,355,505 Est. Cost $7.16 Unrealized -22.5%
REPL Replimune Group Inc 1.0%
Value $16.78M Shares 1,806,529 Est. Cost $12.12 Unrealized -28.0%
RNAM Avidity Biosciences Inc 1.0%
Value $16.61M Shares 584,801 Est. Cost $30.72 Unrealized -3.0%
SMMT Summit Therapeutics Inc 0.9%
Value $14.9M Shares 700,000 Est. Cost Unrealized
SNDX Syndax Pharmaceuticals Inc 0.9%
Value $14.28M Shares 1,524,440 Est. Cost $16.13 Unrealized -31.8%
RYTM Rhythm Pharmaceuticals Inc 0.9%
Value $14.22M Shares 225,000 Est. Cost $53.22 Unrealized +15.0%
REPL Replimune Group Inc 0.9%
Value $13.94M Shares 1,500,000 Est. Cost $12.12 Unrealized -28.0%
Cidara Therapeutics Inc 0.7%
Value $12.23M Shares 251,031 Est. Cost $48.71 Unrealized
IMTX Immatics N.V 0.7%
Value $12.05M Shares 2,240,528 Est. Cost $5.85 Unrealized -15.2%
ROIV Roivant Sciences Ltd 0.7%
Value $11.27M Shares 1,000,000 Est. Cost $10.83 Unrealized +0.1%
EXAS Exact Sciences Corp 0.7%
Value $11.07M Shares 208,300 Est. Cost $50.80 Unrealized 0.0%
PHVS Pharvaris N V 0.6%
Value $10.31M Shares 585,532 Est. Cost $20.79 Unrealized -22.5%
INBX Inhibrx Biosciences Inc 0.6%
Value $10.11M Shares 708,678 Est. Cost $14.93 Unrealized -13.4%
RCUS Arcus Biosciences Inc 0.6%
Value $9.898M Shares 1,216,016 Est. Cost $11.15 Unrealized -23.4%
Y-mAbs Therapeutics Inc 0.6%
Value $9.896M Shares 2,194,278 Est. Cost $26.75 Unrealized
AXSM Axsome Therapeutics Inc 0.6%
Value $9.772M Shares 93,610 Est. Cost $80.00 Unrealized +32.4%
BIOA BioAge Labs Inc 0.6%
Value $9.519M Shares 2,304,901 Est. Cost $20.04 Unrealized -79.9%
EWTX Edgewise Therapeutics Inc 0.6%
Value $9.398M Shares 716,873 Est. Cost $16.17 Unrealized -10.8%
IMNM Immunome Inc 0.4%
Value $7.24M Shares 778,476 Est. Cost $18.47 Unrealized -55.6%
DYN Dyne Therapeutics Inc 0.4%
Value $5.854M Shares 614,865 Est. Cost $20.14 Unrealized -45.3%
SVRA Savara Inc 0.3%
Value $5.603M Shares 2,457,352 Est. Cost $4.16 Unrealized -34.7%
Cidara Therapeutics Inc 0.3%
Value $4.871M Shares 100,000 Est. Cost $48.71 Unrealized
COGT Cogent Biosciences Inc 0.3%
Value $4.739M Shares 660,000 Est. Cost $7.16 Unrealized -22.5%
APGE Apogee Therapeutics Inc 0.2%
Value $3.308M Shares 76,180 Est. Cost $38.04 Unrealized 0.0%
Nextcure Inc 0.1%
Value $1.229M Shares 2,671,856 Est. Cost $10.01 Unrealized
ESTA Establishment Labs Hldgs Inc 0.1%
Value $1.201M Shares 28,120 Est. Cost $47.17 Unrealized -26.1%
JBIO Jade Biosciences Inc 0.1%
Value $1.073M Shares 107,391 Est. Cost $33.31 Unrealized 0.0%
Metsera Inc 0.1%
Value $1.03M Shares 36,191 Est. Cost $27.22 Unrealized
SRRK Scholar Rock Hldg Corp 0.1%
Value $937K Shares 26,440 Est. Cost $38.47 Unrealized -18.4%
BOLT Bolt Biotherapeutics Inc 0.0%
Value $795K Shares 137,721 Est. Cost $6.62 Unrealized 0.0%
WVE Wave Life Sciences Ltd 0.0%
Value $766K Shares 117,903 Est. Cost $6.60 Unrealized 0.0%
GPCR Structure Therapeutics Inc 0.0%
Value $712K Shares 34,353 Est. Cost $34.06 Unrealized
PRAX Praxis Precision Medicines Inc 0.0%
Value $661K Shares 15,717 Est. Cost $62.45 Unrealized -39.0%
Ikena Oncology Inc 0.0%
Value $513K Shares 382,616 Est. Cost $2.66 Unrealized
IRON Disc Medicine Inc 0.0%
Value $387K Shares 7,312 Est. Cost $42.38 Unrealized +10.8%