RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q3 2018 (← Previous) (Next →)

Filing Date: Nov 14, 2018

Total Value: $1.871B (100.0% shares, 0.0% debt)

Holdings (26)

WVE WAVE LIFE SCIENCES LTD 20.1%

Value $376M Shares 7,512,049 Share Price $50.00 * Est. Cost/Share $16.44 Unrealized @ Report Date +174.5%

ASND ASCENDIS PHARMA A S 16.1%

Value $300M Shares 4,240,536 Share Price $70.86 Est. Cost/Share $17.96 Unrealized @ Report Date —

— SOLID BIOSCIENCES INC 6.8%

Value $127M Shares 2,689,444 Share Price $47.18 Est. Cost/Share $7.50 Unrealized @ Report Date —

— ENDOCYTE INC 5.9%

Value $110M Shares 6,196,143 Share Price $17.76 Est. Cost/Share $8.59 Unrealized @ Report Date —

— ZOGENIX INC 5.0%

Value $93.19M Shares 1,878,768 Share Price $49.60 Est. Cost/Share $29.66 Unrealized @ Report Date —

— MYOVANT SCIENCES LTD 4.9%

Value $91.65M Shares 3,451,859 Share Price $26.55 Est. Cost/Share $14.71 Unrealized @ Report Date —

BCRX BIOCRYST PHARMACEUTICALS 3.8%

Value $70.46M Shares 9,234,692 Share Price $7.63 * Est. Cost/Share $7.23 Unrealized @ Report Date -7.1%

— RA PHARMACEUTICALS INC 3.7%

Value $69.68M Shares 3,851,808 Share Price $18.09 Est. Cost/Share $8.78 Unrealized @ Report Date —

IFRX INFLARX NV 3.6%

Value $67.54M Shares 1,967,848 Share Price $34.32 * Est. Cost/Share $20.89 Unrealized @ Report Date +54.4%

— IMMUNOMEDICS INC 3.5%

Value $64.98M Shares 3,119,778 Share Price $20.83 Est. Cost/Share $23.67 Unrealized @ Report Date —

— DICERNA PHARMACEUTICALS INC 3.2%

Value $60.02M Shares 3,933,489 Share Price $15.26 Est. Cost/Share $18.43 Unrealized @ Report Date —

RYTM RHYTHM PHARMACEUTICALS INC 3.0%

Value $56.89M Shares 1,950,332 Share Price $29.17 * Est. Cost/Share $28.23 Unrealized @ Report Date +11.9%

ARVN ARVINAS INC 2.8%

Value $52.95M Shares 3,138,412 Share Price $16.87 * Est. Cost/Share $16.46 Unrealized @ Report Date 0.0%

— SAGE THERAPEUTICS INC 2.7%

Value $49.57M Shares 350,933 Share Price $141.25 Est. Cost/Share $164.71 Unrealized @ Report Date —

CRNX CRINETICS PHARMACEUTICALS INC 2.6%

Value $48.73M Shares 1,701,017 Share Price $28.65 * Est. Cost/Share $29.69 Unrealized @ Report Date 0.0%

TGTX TG THERAPEUTICS INC 2.5%

Value $45.91M Shares 8,198,337 Share Price $5.60 * Est. Cost/Share $12.35 Unrealized @ Report Date -7.5%

— MOMENTA PHARMACEUTICALS INC 2.2%

Value $40.98M Shares 1,558,357 Share Price $26.30 Est. Cost/Share $20.45 Unrealized @ Report Date —

KALV KALVISTA PHARMACEUTICALS INC 1.7%

Value $31.86M Shares 1,441,070 Share Price $22.11 * Est. Cost/Share $9.16 Unrealized @ Report Date +47.5%

— EIDOS THERAPEUTICS INC 1.2%

Value $21.58M Shares 2,162,671 Share Price $9.98 Est. Cost/Share $20.34 Unrealized @ Report Date —

— KALA PHARMACEUTICALS INC 1.1%

Value $20.86M Shares 2,113,236 Share Price $9.87 Est. Cost/Share $22.84 Unrealized @ Report Date —

— PROGENICS PHARMACEUTICALS INC 1.0%

Value $19M Shares 3,030,303 Share Price $6.27 Est. Cost/Share $6.27 Unrealized @ Report Date —

— SCPHARMACEUTICALS INC 0.9%

Value $16.77M Shares 2,857,143 Share Price $5.87 Est. Cost/Share $12.09 Unrealized @ Report Date —

APLS APELLIS PHARMACEUTICALS INC 0.9%

Value $16M Shares 900,000 Share Price $17.78 * Est. Cost/Share $14.72 Unrealized @ Report Date +25.6%

IOVA IOVANCE BIOTHERAPEUTICS INC 0.7%

Value $12.61M Shares 1,121,153 Share Price $11.25 * Est. Cost/Share $14.93 Unrealized @ Report Date -4.9%

— GLYCOMIMETICS INC 0.2%

Value $3.651M Shares 253,547 Share Price $14.40 Est. Cost/Share $16.23 Unrealized @ Report Date —

— PROTEON THERAPEUTICS INC 0.1%

Value $2.608M Shares 1,337,462 Share Price $1.95 Est. Cost/Share $1.53 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	7,512,049	$376M	20.1%	$50.00 *	$16.44	+174.5%	SHS	Y95308105
ASND	ASCENDIS PHARMA A S	4,240,536	$300M	16.1%	$70.86	$17.96	—	SPONSORED ADR	04351P101
—	SOLID BIOSCIENCES INC	2,689,444	$127M	6.8%	$47.18	$7.50	—	COM	83422E105
—	ENDOCYTE INC	6,196,143	$110M	5.9%	$17.76	$8.59	—	COM	29269A102
—	ZOGENIX INC	1,878,768	$93.19M	5.0%	$49.60	$29.66	—	COM NEW	98978L204
—	MYOVANT SCIENCES LTD	3,451,859	$91.65M	4.9%	$26.55	$14.71	—	COM	G637AM102
BCRX	BIOCRYST PHARMACEUTICALS	9,234,692	$70.46M	3.8%	$7.63 *	$7.23	-7.1%	COM	09058V103
—	RA PHARMACEUTICALS INC	3,851,808	$69.68M	3.7%	$18.09	$8.78	—	COM	74933V108
IFRX	INFLARX NV	1,967,848	$67.54M	3.6%	$34.32 *	$20.89	+54.4%	COM	N44821101
—	IMMUNOMEDICS INC	3,119,778	$64.98M	3.5%	$20.83	$23.67	—	COM	452907108
—	DICERNA PHARMACEUTICALS INC	3,933,489	$60.02M	3.2%	$15.26	$18.43	—	COM	253031108
RYTM	RHYTHM PHARMACEUTICALS INC	1,950,332	$56.89M	3.0%	$29.17 *	$28.23	+11.9%	COM	76243J105
ARVN	ARVINAS INC	3,138,412	$52.95M	2.8%	$16.87 *	$16.46	0.0%	COM	04335A105
—	SAGE THERAPEUTICS INC	350,933	$49.57M	2.7%	$141.25	$164.71	—	COM	78667J108
CRNX	CRINETICS PHARMACEUTICALS INC	1,701,017	$48.73M	2.6%	$28.65 *	$29.69	0.0%	COM	22663K107
TGTX	TG THERAPEUTICS INC	8,198,337	$45.91M	2.5%	$5.60 *	$12.35	-7.5%	COM	88322Q108
—	MOMENTA PHARMACEUTICALS INC	1,558,357	$40.98M	2.2%	$26.30	$20.45	—	COM	60877T100
KALV	KALVISTA PHARMACEUTICALS INC	1,441,070	$31.86M	1.7%	$22.11 *	$9.16	+47.5%	COM	483497103
—	EIDOS THERAPEUTICS INC	2,162,671	$21.58M	1.2%	$9.98	$20.34	—	COM	28249H104
—	KALA PHARMACEUTICALS INC	2,113,236	$20.86M	1.1%	$9.87	$22.84	—	COM	483119103
—	PROGENICS PHARMACEUTICALS INC	3,030,303	$19M	1.0%	$6.27	$6.27	—	COM	743187106
—	SCPHARMACEUTICALS INC	2,857,143	$16.77M	0.9%	$5.87	$12.09	—	COM	810648105
APLS	APELLIS PHARMACEUTICALS INC	900,000	$16M	0.9%	$17.78 *	$14.72	+25.6%	COM	03753U106
IOVA	IOVANCE BIOTHERAPEUTICS INC	1,121,153	$12.61M	0.7%	$11.25 *	$14.93	-4.9%	COM	462260100
—	GLYCOMIMETICS INC	253,547	$3.651M	0.2%	$14.40	$16.23	—	COM	38000Q102
—	PROTEON THERAPEUTICS INC	1,337,462	$2.608M	0.1%	$1.95	$1.53	—	COM	74371L109