RA CAPITAL MANAGEMENT, L.P. Diversified Active

CIK: 0001346824 · Show all filings

Period: Q4 2018 (← Previous) (Next →)

Filing Date: Feb 14, 2019

Total Value ($000): $1,717,985 (100.0% shares, 0.0% debt)

Holdings (25)

WVE WAVE LIFE SCIENCES LTD 18.4%

Value ($000) $315,807 Shares 7,512,049 Est. Cost $16.44 Unrealized +170.5%

ASND ASCENDIS PHARMA A S 15.5%

Value ($000) $265,670 Shares 4,240,536 Est. Cost $17.96 Unrealized —

— SYNTHORX INC 9.8%

Value ($000) $169,014 Shares 9,724,598 Est. Cost $17.38 Unrealized —

— ZOGENIX INC 5.1%

Value ($000) $86,854 Shares 2,382,168 Est. Cost $31.10 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 5.0%

Value ($000) $86,029 Shares 10,660,349 Est. Cost $7.30 Unrealized +6.5%

— ORCHARD THERAPEUTICS PLC 4.4%

Value ($000) $76,227 Shares 4,845,933 Est. Cost $15.73 Unrealized —

IFRX INFLARX NV 4.4%

Value ($000) $75,835 Shares 2,085,089 Est. Cost $21.44 Unrealized +43.6%

— SOLID BIOSCIENCES INC 4.2%

Value ($000) $72,077 Shares 2,689,444 Est. Cost $7.50 Unrealized —

— MYOVANT SCIENCES LTD 3.5%

Value ($000) $60,907 Shares 3,711,549 Est. Cost $14.83 Unrealized —

— EIDOS THERAPEUTICS INC 3.4%

Value ($000) $59,206 Shares 2,162,671 Est. Cost $20.34 Unrealized —

CRNX CRINETICS PHARMACEUTICALS INC 3.3%

Value ($000) $56,238 Shares 1,875,209 Est. Cost $29.55 Unrealized -4.7%

RYTM RHYTHM PHARMACEUTICALS INC 3.1%

Value ($000) $52,425 Shares 1,950,332 Est. Cost $28.23 Unrealized -2.1%

— IMMUNOMEDICS INC 2.5%

Value ($000) $43,116 Shares 3,021,466 Est. Cost $23.67 Unrealized —

ARVN ARVINAS INC 2.3%

Value ($000) $40,329 Shares 3,138,412 Est. Cost $16.46 Unrealized -3.6%

— RA PHARMACEUTICALS INC 2.0%

Value ($000) $33,963 Shares 4,858,260 Est. Cost $8.41 Unrealized —

TGTX TG THERAPEUTICS INC 2.0%

Value ($000) $33,613 Shares 8,198,337 Est. Cost $12.35 Unrealized -59.7%

KALV KALVISTA PHARMACEUTICALS INC 1.7%

Value ($000) $28,461 Shares 1,441,070 Est. Cost $9.16 Unrealized +119.4%

— MOMENTA PHARMACEUTICALS INC 1.6%

Value ($000) $28,244 Shares 2,558,357 Est. Cost $16.77 Unrealized —

— DICERNA PHARMACEUTICALS INC 1.5%

Value ($000) $26,262 Shares 2,456,669 Est. Cost $18.43 Unrealized —

— EIGER BIOPHARMACEUTICALS INC 1.4%

Value ($000) $24,541 Shares 2,415,458 Est. Cost $10.16 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 1.4%

Value ($000) $24,076 Shares 2,720,452 Est. Cost $11.82 Unrealized -18.4%

MRNA MODERNA INC 1.3%

Value ($000) $23,124 Shares 1,514,326 Est. Cost $16.43 Unrealized 0.0%

— KALA PHARMACEUTICALS INC 1.3%

Value ($000) $22,188 Shares 4,537,478 Est. Cost $13.25 Unrealized —

— SCPHARMACEUTICALS INC 0.6%

Value ($000) $10,743 Shares 2,857,143 Est. Cost $12.09 Unrealized —

— PROTEON THERAPEUTICS INC 0.2%

Value ($000) $3,036 Shares 1,337,462 Est. Cost $1.53 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	7,512,049	$315,807	18.4%	$16.44	+170.5%	SHS	Y95308105
ASND	ASCENDIS PHARMA A S	4,240,536	$265,670	15.5%	$17.96	—	SPONSORED ADR	04351P101
—	SYNTHORX INC	9,724,598	$169,014	9.8%	$17.38	—	COM	87167A103
—	ZOGENIX INC	2,382,168	$86,854	5.1%	$31.10	—	COM NEW	98978L204
BCRX	BIOCRYST PHARMACEUTICALS	10,660,349	$86,029	5.0%	$7.30	+6.5%	COM	09058V103
—	ORCHARD THERAPEUTICS PLC	4,845,933	$76,227	4.4%	$15.73	—	ADS	68570P101
IFRX	INFLARX NV	2,085,089	$75,835	4.4%	$21.44	+43.6%	COM	N44821101
—	SOLID BIOSCIENCES INC	2,689,444	$72,077	4.2%	$7.50	—	COM	83422E105
—	MYOVANT SCIENCES LTD	3,711,549	$60,907	3.5%	$14.83	—	COM	G637AM102
—	EIDOS THERAPEUTICS INC	2,162,671	$59,206	3.4%	$20.34	—	COM	28249H104
CRNX	CRINETICS PHARMACEUTICALS INC	1,875,209	$56,238	3.3%	$29.55	-4.7%	COM	22663K107
RYTM	RHYTHM PHARMACEUTICALS INC	1,950,332	$52,425	3.1%	$28.23	-2.1%	COM	76243J105
—	IMMUNOMEDICS INC	3,021,466	$43,116	2.5%	$23.67	—	COM	452907108
ARVN	ARVINAS INC	3,138,412	$40,329	2.3%	$16.46	-3.6%	COM	04335A105
—	RA PHARMACEUTICALS INC	4,858,260	$33,963	2.0%	$8.41	—	COM	74933V108
TGTX	TG THERAPEUTICS INC	8,198,337	$33,613	2.0%	$12.35	-59.7%	COM	88322Q108
KALV	KALVISTA PHARMACEUTICALS INC	1,441,070	$28,461	1.7%	$9.16	+119.4%	COM	483497103
—	MOMENTA PHARMACEUTICALS INC	2,558,357	$28,244	1.6%	$16.77	—	COM	60877T100
—	DICERNA PHARMACEUTICALS INC	2,456,669	$26,262	1.5%	$18.43	—	COM	253031108
—	EIGER BIOPHARMACEUTICALS INC	2,415,458	$24,541	1.4%	$10.16	—	COM	28249U105
IOVA	IOVANCE BIOTHERAPEUTICS INC	2,720,452	$24,076	1.4%	$11.82	-18.4%	COM	462260100
MRNA	MODERNA INC	1,514,326	$23,124	1.3%	$16.43	0.0%	COM	60770K107
—	KALA PHARMACEUTICALS INC	4,537,478	$22,188	1.3%	$13.25	—	COM	483119103
—	SCPHARMACEUTICALS INC	2,857,143	$10,743	0.6%	$12.09	—	COM	810648105
—	PROTEON THERAPEUTICS INC	1,337,462	$3,036	0.2%	$1.53	—	COM	74371L109