RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q4 2018 (← Previous) (Next →)

Filing Date: Feb 14, 2019

Total Value: $1.718B (100.0% shares, 0.0% debt)

Holdings (25)

WVE WAVE LIFE SCIENCES LTD 18.4%

Value $316M Shares 7,512,049 Share Price $42.04 * Est. Cost/Share $16.44 Unrealized @ Report Date +170.5%

ASND ASCENDIS PHARMA A S 15.5%

Value $266M Shares 4,240,536 Share Price $62.65 Est. Cost/Share $17.96 Unrealized @ Report Date —

— SYNTHORX INC 9.8%

Value $169M Shares 9,724,598 Share Price $17.38 Est. Cost/Share $17.38 Unrealized @ Report Date —

— ZOGENIX INC 5.1%

Value $86.85M Shares 2,382,168 Share Price $36.46 Est. Cost/Share $31.10 Unrealized @ Report Date —

BCRX BIOCRYST PHARMACEUTICALS 5.0%

Value $86.03M Shares 10,660,349 Share Price $8.07 * Est. Cost/Share $7.30 Unrealized @ Report Date +6.5%

— ORCHARD THERAPEUTICS PLC 4.4%

Value $76.23M Shares 4,845,933 Share Price $15.73 Est. Cost/Share $15.73 Unrealized @ Report Date —

IFRX INFLARX NV 4.4%

Value $75.83M Shares 2,085,089 Share Price $36.37 * Est. Cost/Share $21.44 Unrealized @ Report Date +43.6%

— SOLID BIOSCIENCES INC 4.2%

Value $72.08M Shares 2,689,444 Share Price $26.80 Est. Cost/Share $7.50 Unrealized @ Report Date —

— MYOVANT SCIENCES LTD 3.5%

Value $60.91M Shares 3,711,549 Share Price $16.41 Est. Cost/Share $14.83 Unrealized @ Report Date —

— EIDOS THERAPEUTICS INC 3.4%

Value $59.21M Shares 2,162,671 Share Price $27.38 Est. Cost/Share $20.34 Unrealized @ Report Date —

CRNX CRINETICS PHARMACEUTICALS INC 3.3%

Value $56.24M Shares 1,875,209 Share Price $29.99 * Est. Cost/Share $29.55 Unrealized @ Report Date -4.7%

RYTM RHYTHM PHARMACEUTICALS INC 3.1%

Value $52.42M Shares 1,950,332 Share Price $26.88 * Est. Cost/Share $28.23 Unrealized @ Report Date -2.1%

— IMMUNOMEDICS INC 2.5%

Value $43.12M Shares 3,021,466 Share Price $14.27 Est. Cost/Share $23.67 Unrealized @ Report Date —

ARVN ARVINAS INC 2.3%

Value $40.33M Shares 3,138,412 Share Price $12.85 * Est. Cost/Share $16.46 Unrealized @ Report Date -3.6%

— RA PHARMACEUTICALS INC 2.0%

Value $33.96M Shares 4,858,260 Share Price $6.99 Est. Cost/Share $8.41 Unrealized @ Report Date —

TGTX TG THERAPEUTICS INC 2.0%

Value $33.61M Shares 8,198,337 Share Price $4.10 * Est. Cost/Share $12.35 Unrealized @ Report Date -59.7%

KALV KALVISTA PHARMACEUTICALS INC 1.7%

Value $28.46M Shares 1,441,070 Share Price $19.75 Est. Cost/Share $9.16 Unrealized @ Report Date +119.4%

— MOMENTA PHARMACEUTICALS INC 1.6%

Value $28.24M Shares 2,558,357 Share Price $11.04 Est. Cost/Share $16.77 Unrealized @ Report Date —

— DICERNA PHARMACEUTICALS INC 1.5%

Value $26.26M Shares 2,456,669 Share Price $10.69 Est. Cost/Share $18.43 Unrealized @ Report Date —

— EIGER BIOPHARMACEUTICALS INC 1.4%

Value $24.54M Shares 2,415,458 Share Price $10.16 Est. Cost/Share $10.16 Unrealized @ Report Date —

IOVA IOVANCE BIOTHERAPEUTICS INC 1.4%

Value $24.08M Shares 2,720,452 Share Price $8.85 * Est. Cost/Share $11.82 Unrealized @ Report Date -18.4%

MRNA MODERNA INC 1.3%

Value $23.12M Shares 1,514,326 Share Price $15.27 * Est. Cost/Share $16.43 Unrealized @ Report Date 0.0%

— KALA PHARMACEUTICALS INC 1.3%

Value $22.19M Shares 4,537,478 Share Price $4.89 Est. Cost/Share $13.25 Unrealized @ Report Date —

— SCPHARMACEUTICALS INC 0.6%

Value $10.74M Shares 2,857,143 Share Price $3.76 Est. Cost/Share $12.09 Unrealized @ Report Date —

— PROTEON THERAPEUTICS INC 0.2%

Value $3.036M Shares 1,337,462 Share Price $2.27 Est. Cost/Share $1.53 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	7,512,049	$316M	18.4%	$42.04 *	$16.44	+170.5%	SHS	Y95308105
ASND	ASCENDIS PHARMA A S	4,240,536	$266M	15.5%	$62.65	$17.96	—	SPONSORED ADR	04351P101
—	SYNTHORX INC	9,724,598	$169M	9.8%	$17.38	$17.38	—	COM	87167A103
—	ZOGENIX INC	2,382,168	$86.85M	5.1%	$36.46	$31.10	—	COM NEW	98978L204
BCRX	BIOCRYST PHARMACEUTICALS	10,660,349	$86.03M	5.0%	$8.07 *	$7.30	+6.5%	COM	09058V103
—	ORCHARD THERAPEUTICS PLC	4,845,933	$76.23M	4.4%	$15.73	$15.73	—	ADS	68570P101
IFRX	INFLARX NV	2,085,089	$75.83M	4.4%	$36.37 *	$21.44	+43.6%	COM	N44821101
—	SOLID BIOSCIENCES INC	2,689,444	$72.08M	4.2%	$26.80	$7.50	—	COM	83422E105
—	MYOVANT SCIENCES LTD	3,711,549	$60.91M	3.5%	$16.41	$14.83	—	COM	G637AM102
—	EIDOS THERAPEUTICS INC	2,162,671	$59.21M	3.4%	$27.38	$20.34	—	COM	28249H104
CRNX	CRINETICS PHARMACEUTICALS INC	1,875,209	$56.24M	3.3%	$29.99 *	$29.55	-4.7%	COM	22663K107
RYTM	RHYTHM PHARMACEUTICALS INC	1,950,332	$52.42M	3.1%	$26.88 *	$28.23	-2.1%	COM	76243J105
—	IMMUNOMEDICS INC	3,021,466	$43.12M	2.5%	$14.27	$23.67	—	COM	452907108
ARVN	ARVINAS INC	3,138,412	$40.33M	2.3%	$12.85 *	$16.46	-3.6%	COM	04335A105
—	RA PHARMACEUTICALS INC	4,858,260	$33.96M	2.0%	$6.99	$8.41	—	COM	74933V108
TGTX	TG THERAPEUTICS INC	8,198,337	$33.61M	2.0%	$4.10 *	$12.35	-59.7%	COM	88322Q108
KALV	KALVISTA PHARMACEUTICALS INC	1,441,070	$28.46M	1.7%	$19.75	$9.16	+119.4%	COM	483497103
—	MOMENTA PHARMACEUTICALS INC	2,558,357	$28.24M	1.6%	$11.04	$16.77	—	COM	60877T100
—	DICERNA PHARMACEUTICALS INC	2,456,669	$26.26M	1.5%	$10.69	$18.43	—	COM	253031108
—	EIGER BIOPHARMACEUTICALS INC	2,415,458	$24.54M	1.4%	$10.16	$10.16	—	COM	28249U105
IOVA	IOVANCE BIOTHERAPEUTICS INC	2,720,452	$24.08M	1.4%	$8.85 *	$11.82	-18.4%	COM	462260100
MRNA	MODERNA INC	1,514,326	$23.12M	1.3%	$15.27 *	$16.43	0.0%	COM	60770K107
—	KALA PHARMACEUTICALS INC	4,537,478	$22.19M	1.3%	$4.89	$13.25	—	COM	483119103
—	SCPHARMACEUTICALS INC	2,857,143	$10.74M	0.6%	$3.76	$12.09	—	COM	810648105
—	PROTEON THERAPEUTICS INC	1,337,462	$3.036M	0.2%	$2.27	$1.53	—	COM	74371L109