GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q1 2020 (← Previous) (Next →)

Filing Date: May 15, 2020

Total Value: $957M (100.0% shares, 0.0% debt)

Holdings (36)

ACAD ACADIA PHARMACEUTICALS INC 8.8%

Value $84.32M Shares 1,995,747 Est. Cost $29.42 Unrealized +40.1%

— ZYMEWORKS INC 8.6%

Value $82.46M Shares 2,324,688 Est. Cost $8968.42 Unrealized —

PTCT PTC THERAPEUTICS INC 8.2%

Value $78.67M Shares 1,763,387 Est. Cost $28.65 Unrealized +75.7%

IOVA IOVANCE BIOTHERAPEUTICS INC 7.5%

Value $71.47M Shares 2,387,606 Est. Cost $9.91 Unrealized +167.6%

— CONSTELLATION PHARMCETICLS I 6.5%

Value $62.15M Shares 1,977,502 Est. Cost $40.43 Unrealized —

UTHR UNITED THERAPEUTICS CORP DEL 5.5%

Value $52.75M Shares 556,252 Est. Cost $81.88 Unrealized +16.1%

— SAGE THERAPEUTICS INC 5.5%

Value $52.4M Shares 1,824,479 Est. Cost $47.69 Unrealized —

— NEXTCURE INC 5.1%

Value $48.67M Shares 1,312,956 Est. Cost $53.71 Unrealized —

— ACCELERON PHARMA INC 5.0%

Value $48.14M Shares 535,627 Est. Cost $18289.17 Unrealized —

— GW PHARMACEUTICALS PLC 4.1%

Value $39.41M Shares 450,000 Est. Cost $92.92 Unrealized —

— BIOHAVEN PHARMACTL HLDG CO L 3.6%

Value $34.03M Shares 1,000,000 Est. Cost $34.03 Unrealized —

— ABIOMED INC 3.3%

Value $31.38M Shares 216,144 Est. Cost $145.16 Unrealized —

— MOMENTA PHARMACEUTICALS INC 2.8%

Value $26.64M Shares 979,400 Est. Cost $162.34 Unrealized —

TGTX TG THERAPEUTICS INC 2.6%

Value $25.15M Shares 2,556,324 Est. Cost $7.60 Unrealized +66.1%

— MYOKARDIA INC 2.4%

Value $23.44M Shares 500,000 Est. Cost $46.88 Unrealized —

PRTA PROTHENA CORP PLC 2.3%

Value $22.29M Shares 2,082,841 Est. Cost $10.02 Unrealized +20.9%

— BIOHAVEN PHARMACTL HLDG CO L 2.1%

Value $19.8M Shares 581,905 Est. Cost $34.03 Unrealized —

— MYOKARDIA INC 1.8%

Value $17.07M Shares 364,163 Est. Cost $46.88 Unrealized —

— ARENA PHARMACEUTICALS INC 1.7%

Value $16.27M Shares 387,499 Est. Cost $42.00 Unrealized —

— ABEONA THERAPEUTICS INC 1.6%

Value $15.15M Shares 7,213,012 Est. Cost $2.82 Unrealized —

— CHEMOCENTRYX INC 1.5%

Value $14.36M Shares 357,379 Est. Cost $40.18 Unrealized —

— AXONICS MODULATION TECHNOLOG 1.4%

Value $13.8M Shares 542,929 Est. Cost $27.39 Unrealized —

— MOLECULAR TEMPLATES INC 1.1%

Value $10.96M Shares 825,000 Est. Cost $13.99 Unrealized —

TGTX TG THERAPEUTICS INC 1.0%

Value $9.84M Shares 1,000,000 Est. Cost $7.60 Unrealized +66.1%

— MILLENDO THERAPEUTICS INC 1.0%

Value $9.133M Shares 1,729,759 Est. Cost $7.64 Unrealized —

CYTK CYTOKINETICS INC 0.8%

Value $7.83M Shares 664,097 Est. Cost $12.16 Unrealized +4.9%

VRAYQ VIEWRAY INC 0.7%

Value $6.935M Shares 2,773,811 Est. Cost $3.08 Unrealized -8.1%

LQDA LIQUIDIA TECHNOLOGIES INC 0.6%

Value $6.019M Shares 1,277,955 Est. Cost $4.01 Unrealized +23.5%

AXSM AXSOME THERAPEUTICS INC 0.6%

Value $5.889M Shares 100,100 Est. Cost $81.38 Unrealized +0.1%

ARVN ARVINAS INC 0.5%

Value $4.769M Shares 118,330 Est. Cost $29.28 Unrealized +59.8%

— MENLO THERAPEUTICS INC 0.5%

Value $4.427M Shares 1,652,013 Est. Cost $7.51 Unrealized —

ARVN ARVINAS INC 0.4%

Value $4.171M Shares 103,500 Est. Cost $29.28 Unrealized +59.8%

SGMO SANGAMO THERAPEUTICS INC 0.4%

Value $4.035M Shares 633,505 Est. Cost $7.42 Unrealized 0.0%

KURA KURA ONCOLOGY INC 0.2%

Value $1.788M Shares 179,700 Est. Cost $12.73 Unrealized -10.1%

CTMX CYTOMX THERAPEUTICS INC 0.1%

Value $1.072M Shares 139,718 Est. Cost $6.97 Unrealized 0.0%

— NEOLEUKIN THERAPEUTICS INC 0.0%

Value $459K Shares 40,347 Est. Cost $11.38 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ACAD	ACADIA PHARMACEUTICALS INC	1,995,747	$84.32M	8.8%	$29.42	+40.1%	COM	004225108
—	ZYMEWORKS INC	2,324,688	$82.46M	8.6%	$8968.42	—	COM	98985W102
PTCT	PTC THERAPEUTICS INC	1,763,387	$78.67M	8.2%	$28.65	+75.7%	COM	69366J200
IOVA	IOVANCE BIOTHERAPEUTICS INC	2,387,606	$71.47M	7.5%	$9.91	+167.6%	COM	462260100
—	CONSTELLATION PHARMCETICLS I	1,977,502	$62.15M	6.5%	$40.43	—	COM	210373106
UTHR	UNITED THERAPEUTICS CORP DEL	556,252	$52.75M	5.5%	$81.88	+16.1%	COM	91307C102
—	SAGE THERAPEUTICS INC	1,824,479	$52.4M	5.5%	$47.69	—	COM	78667J108
—	NEXTCURE INC	1,312,956	$48.67M	5.1%	$53.71	—	COM	65343E108
—	ACCELERON PHARMA INC	535,627	$48.14M	5.0%	$18289.17	—	COM	00434H108
—	GW PHARMACEUTICALS PLC	450,000	$39.41M	4.1%	$92.92	—	ADS	36197T103
—	BIOHAVEN PHARMACTL HLDG CO L	1,000,000	$34.03M	3.6%	$34.03	—	Call	G11196105
—	ABIOMED INC	216,144	$31.38M	3.3%	$145.16	—	COM	003654100
—	MOMENTA PHARMACEUTICALS INC	979,400	$26.64M	2.8%	$162.34	—	COM	60877T100
TGTX	TG THERAPEUTICS INC	2,556,324	$25.15M	2.6%	$7.60	+66.1%	COM	88322Q108
—	MYOKARDIA INC	500,000	$23.44M	2.4%	$46.88	—	Call	62857M105
PRTA	PROTHENA CORP PLC	2,082,841	$22.29M	2.3%	$10.02	+20.9%	SHS	G72800108
—	BIOHAVEN PHARMACTL HLDG CO L	581,905	$19.8M	2.1%	$34.03	—	COM	G11196105
—	MYOKARDIA INC	364,163	$17.07M	1.8%	$46.88	—	COM	62857M105
—	ARENA PHARMACEUTICALS INC	387,499	$16.27M	1.7%	$42.00	—	COM NEW	040047607
—	ABEONA THERAPEUTICS INC	7,213,012	$15.15M	1.6%	$2.82	—	COM	00289Y107
—	CHEMOCENTRYX INC	357,379	$14.36M	1.5%	$40.18	—	COM	16383L106
—	AXONICS MODULATION TECHNOLOG	542,929	$13.8M	1.4%	$27.39	—	COM	05465P101
—	MOLECULAR TEMPLATES INC	825,000	$10.96M	1.1%	$13.99	—	COM	608550109
TGTX	TG THERAPEUTICS INC	1,000,000	$9.84M	1.0%	$7.60	+66.1%	Call	88322Q108
—	MILLENDO THERAPEUTICS INC	1,729,759	$9.133M	1.0%	$7.64	—	COM	60040X103
CYTK	CYTOKINETICS INC	664,097	$7.83M	0.8%	$12.16	+4.9%	COM NEW	23282W605
VRAYQ	VIEWRAY INC	2,773,811	$6.935M	0.7%	$3.08	-8.1%	COM	92672L107
LQDA	LIQUIDIA TECHNOLOGIES INC	1,277,955	$6.019M	0.6%	$4.01	+23.5%	COM	53635D202
AXSM	AXSOME THERAPEUTICS INC	100,100	$5.889M	0.6%	$81.38	+0.1%	COM	05464T104
ARVN	ARVINAS INC	118,330	$4.769M	0.5%	$29.28	+59.8%	COM	04335A105
—	MENLO THERAPEUTICS INC	1,652,013	$4.427M	0.5%	$7.51	—	COM	586858102
ARVN	ARVINAS INC	103,500	$4.171M	0.4%	$29.28	+59.8%	Call	04335A105
SGMO	SANGAMO THERAPEUTICS INC	633,505	$4.035M	0.4%	$7.42	0.0%	COM	800677106
KURA	KURA ONCOLOGY INC	179,700	$1.788M	0.2%	$12.73	-10.1%	COM	50127T109
CTMX	CYTOMX THERAPEUTICS INC	139,718	$1.072M	0.1%	$6.97	0.0%	COM	23284F105
—	NEOLEUKIN THERAPEUTICS INC	40,347	$459K	0.0%	$11.38	—	COM	64049K104