GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q2 2020 (← Previous) (Next →)

Filing Date: Aug 14, 2020

Total Value: $1.251B (100.0% shares, 0.0% debt)

Holdings (36)

— CONSTELLATION PHARMCETICLS I 8.4%

Value $105M Shares 3,480,000 Est. Cost $35.95 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 8.2%

Value $102M Shares 3,724,976 Est. Cost $18.15 Unrealized +81.1%

— ZYMEWORKS INC 7.4%

Value $92.87M Shares 2,574,688 Est. Cost $8101.10 Unrealized —

ACAD ACADIA PHARMACEUTICALS INC 7.0%

Value $87.49M Shares 1,804,993 Est. Cost $29.42 Unrealized +63.2%

— SAGE THERAPEUTICS INC 7.0%

Value $87.42M Shares 2,102,368 Est. Cost $46.88 Unrealized —

— ARENA PHARMACEUTICALS INC 6.6%

Value $81.99M Shares 1,302,399 Est. Cost $56.72 Unrealized —

UTHR UNITED THERAPEUTICS CORP DEL 6.0%

Value $75.02M Shares 620,000 Est. Cost $85.03 Unrealized +32.3%

TGTX TG THERAPEUTICS INC 5.2%

Value $64.69M Shares 3,320,808 Est. Cost $9.56 Unrealized +68.5%

— BIOHAVEN PHARMACTL HLDG CO L 4.9%

Value $61.48M Shares 840,900 Est. Cost $46.07 Unrealized —

— GW PHARMACEUTICALS PLC 4.4%

Value $55.22M Shares 450,000 Est. Cost $92.92 Unrealized —

AKBA AKEBIA THERAPEUTICS INC 3.8%

Value $47.67M Shares 3,510,073 Est. Cost $10.35 Unrealized 0.0%

MGNX MACROGENICS INC 3.3%

Value $41.88M Shares 1,500,000 Est. Cost $17.37 Unrealized 0.0%

CYTK CYTOKINETICS INC 2.9%

Value $35.84M Shares 1,520,635 Est. Cost $15.87 Unrealized +18.1%

— GLOBAL BLOOD THERAPEUTICS IN 2.7%

Value $34.23M Shares 542,200 Est. Cost $63.13 Unrealized —

GERN GERON CORP 2.7%

Value $33.57M Shares 15,398,079 Est. Cost $1.49 Unrealized 0.0%

VCEL VERICEL CORP 1.8%

Value $22.25M Shares 1,610,154 Est. Cost $13.53 Unrealized 0.0%

PRTA PROTHENA CORP PLC 1.7%

Value $21.79M Shares 2,082,841 Est. Cost $10.02 Unrealized +10.9%

— NEXTCURE INC 1.7%

Value $21.43M Shares 999,666 Est. Cost $53.71 Unrealized —

— ABEONA THERAPEUTICS INC 1.7%

Value $21.03M Shares 7,213,012 Est. Cost $2.82 Unrealized —

GKOS GLAUKOS CORP 1.5%

Value $19.21M Shares 500,000 Est. Cost $37.23 Unrealized 0.0%

— MOLECULAR TEMPLATES INC 1.5%

Value $18.55M Shares 1,345,397 Est. Cost $13.91 Unrealized —

PTCT PTC THERAPEUTICS INC 1.3%

Value $16.74M Shares 330,000 Est. Cost $28.65 Unrealized +71.5%

— AXONICS MODULATION TECHNOLOG 1.3%

Value $16.13M Shares 459,503 Est. Cost $27.39 Unrealized —

SGMO SANGAMO THERAPEUTICS INC 1.1%

Value $14.16M Shares 1,579,891 Est. Cost $8.53 Unrealized +8.7%

CTMX CYTOMX THERAPEUTICS INC 1.0%

Value $12.07M Shares 1,448,604 Est. Cost $9.06 Unrealized +2.5%

— CALITHERA BIOSCIENCES INC 1.0%

Value $11.94M Shares 2,261,700 Est. Cost $5.28 Unrealized —

LQDA LIQUIDIA TECHNOLOGIES INC 0.9%

Value $10.76M Shares 1,277,955 Est. Cost $4.01 Unrealized +89.1%

ARVN ARVINAS INC 0.5%

Value $6.825M Shares 203,500 Est. Cost $29.28 Unrealized +45.0%

DNLI DENALI THERAPEUTICS INC 0.5%

Value $6.77M Shares 280,000 Est. Cost $23.51 Unrealized 0.0%

VRAYQ VIEWRAY INC 0.5%

Value $6.213M Shares 2,773,811 Est. Cost $3.08 Unrealized -30.7%

— OYSTER PT PHARMA INC 0.5%

Value $6.199M Shares 214,631 Est. Cost $28.88 Unrealized —

— ACCELERON PHARMA INC 0.4%

Value $5.531M Shares 58,056 Est. Cost $18289.17 Unrealized —

— KADMON HLDGS INC 0.3%

Value $3.459M Shares 675,679 Est. Cost $5.12 Unrealized —

— MILLENDO THERAPEUTICS INC 0.2%

Value $2.571M Shares 1,460,697 Est. Cost $7.64 Unrealized —

PBYI PUMA BIOTECHNOLOGY INC 0.1%

Value $965K Shares 92,502 Est. Cost $10.35 Unrealized 0.0%

— NEOLEUKIN THERAPEUTICS INC 0.0%

Value $233K Shares 14,065 Est. Cost $11.38 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	CONSTELLATION PHARMCETICLS I	3,480,000	$105M	8.4%	$35.95	—	COM	210373106
IOVA	IOVANCE BIOTHERAPEUTICS INC	3,724,976	$102M	8.2%	$18.15	+81.1%	COM	462260100
—	ZYMEWORKS INC	2,574,688	$92.87M	7.4%	$8101.10	—	COM	98985W102
ACAD	ACADIA PHARMACEUTICALS INC	1,804,993	$87.49M	7.0%	$29.42	+63.2%	COM	004225108
—	SAGE THERAPEUTICS INC	2,102,368	$87.42M	7.0%	$46.88	—	COM	78667J108
—	ARENA PHARMACEUTICALS INC	1,302,399	$81.99M	6.6%	$56.72	—	COM NEW	040047607
UTHR	UNITED THERAPEUTICS CORP DEL	620,000	$75.02M	6.0%	$85.03	+32.3%	COM	91307C102
TGTX	TG THERAPEUTICS INC	3,320,808	$64.69M	5.2%	$9.56	+68.5%	COM	88322Q108
—	BIOHAVEN PHARMACTL HLDG CO L	840,900	$61.48M	4.9%	$46.07	—	COM	G11196105
—	GW PHARMACEUTICALS PLC	450,000	$55.22M	4.4%	$92.92	—	ADS	36197T103
AKBA	AKEBIA THERAPEUTICS INC	3,510,073	$47.67M	3.8%	$10.35	0.0%	COM	00972D105
MGNX	MACROGENICS INC	1,500,000	$41.88M	3.3%	$17.37	0.0%	COM	556099109
CYTK	CYTOKINETICS INC	1,520,635	$35.84M	2.9%	$15.87	+18.1%	COM NEW	23282W605
—	GLOBAL BLOOD THERAPEUTICS IN	542,200	$34.23M	2.7%	$63.13	—	COM	37890U108
GERN	GERON CORP	15,398,079	$33.57M	2.7%	$1.49	0.0%	COM	374163103
VCEL	VERICEL CORP	1,610,154	$22.25M	1.8%	$13.53	0.0%	COM	92346J108
PRTA	PROTHENA CORP PLC	2,082,841	$21.79M	1.7%	$10.02	+10.9%	SHS	G72800108
—	NEXTCURE INC	999,666	$21.43M	1.7%	$53.71	—	COM	65343E108
—	ABEONA THERAPEUTICS INC	7,213,012	$21.03M	1.7%	$2.82	—	COM	00289Y107
GKOS	GLAUKOS CORP	500,000	$19.21M	1.5%	$37.23	0.0%	COM	377322102
—	MOLECULAR TEMPLATES INC	1,345,397	$18.55M	1.5%	$13.91	—	COM	608550109
PTCT	PTC THERAPEUTICS INC	330,000	$16.74M	1.3%	$28.65	+71.5%	COM	69366J200
—	AXONICS MODULATION TECHNOLOG	459,503	$16.13M	1.3%	$27.39	—	COM	05465P101
SGMO	SANGAMO THERAPEUTICS INC	1,579,891	$14.16M	1.1%	$8.53	+8.7%	COM	800677106
CTMX	CYTOMX THERAPEUTICS INC	1,448,604	$12.07M	1.0%	$9.06	+2.5%	COM	23284F105
—	CALITHERA BIOSCIENCES INC	2,261,700	$11.94M	1.0%	$5.28	—	COM	13089P101
LQDA	LIQUIDIA TECHNOLOGIES INC	1,277,955	$10.76M	0.9%	$4.01	+89.1%	COM	53635D202
ARVN	ARVINAS INC	203,500	$6.825M	0.5%	$29.28	+45.0%	Call	04335A105
DNLI	DENALI THERAPEUTICS INC	280,000	$6.77M	0.5%	$23.51	0.0%	COM	24823R105
VRAYQ	VIEWRAY INC	2,773,811	$6.213M	0.5%	$3.08	-30.7%	COM	92672L107
—	OYSTER PT PHARMA INC	214,631	$6.199M	0.5%	$28.88	—	COM	69242L106
—	ACCELERON PHARMA INC	58,056	$5.531M	0.4%	$18289.17	—	COM	00434H108
—	KADMON HLDGS INC	675,679	$3.459M	0.3%	$5.12	—	COM	48283N106
—	MILLENDO THERAPEUTICS INC	1,460,697	$2.571M	0.2%	$7.64	—	COM	60040X103
PBYI	PUMA BIOTECHNOLOGY INC	92,502	$965K	0.1%	$10.35	0.0%	COM	74587V107
—	NEOLEUKIN THERAPEUTICS INC	14,065	$233K	0.0%	$11.38	—	COM	64049K104