GREAT POINT PARTNERS LLC Quant / Systematic

CIK: 0001281446 · Show all filings

Period: Q3 2020 (← Previous) (Next →)

Filing Date: Nov 16, 2020

Total Value ($000): $1,111,643 (100.0% shares, 0.0% debt)

Holdings (34)

IOVA IOVANCE BIOTHERAPEUTICS INC 11.5%

Value ($000) $127,618 Shares 3,876,600 Est. Cost $18.64 Unrealized +64.5%

— SAGE THERAPEUTICS INC 10.8%

Value ($000) $120,204 Shares 1,966,688 Est. Cost $46.88 Unrealized —

ACAD ACADIA PHARMACEUTICALS INC 7.1%

Value ($000) $79,264 Shares 1,921,563 Est. Cost $30.25 Unrealized +42.7%

— ARENA PHARMACEUTICALS INC 6.7%

Value ($000) $74,558 Shares 996,898 Est. Cost $56.72 Unrealized —

— ZYMEWORKS INC 6.6%

Value ($000) $73,033 Shares 1,567,900 Est. Cost $8101.10 Unrealized —

UTHR UNITED THERAPEUTICS CORP DEL 5.8%

Value ($000) $64,718 Shares 640,773 Est. Cost $85.83 Unrealized +27.8%

— CONSTELLATION PHARMCETICLS I 5.2%

Value ($000) $57,983 Shares 2,861,924 Est. Cost $35.95 Unrealized —

CYTK CYTOKINETICS INC 5.0%

Value ($000) $55,197 Shares 2,549,525 Est. Cost $18.91 Unrealized +23.7%

— GW PHARMACEUTICALS PLC 4.6%

Value ($000) $50,645 Shares 520,232 Est. Cost $93.52 Unrealized —

TGTX TG THERAPEUTICS INC 3.9%

Value ($000) $42,816 Shares 1,600,000 Est. Cost $9.56 Unrealized +140.7%

MGNX MACROGENICS INC 3.4%

Value ($000) $38,042 Shares 1,510,215 Est. Cost $17.37 Unrealized +57.2%

AUPH AURINIA PHARMACEUTICALS INC 3.3%

Value ($000) $36,609 Shares 2,485,327 Est. Cost $14.49 Unrealized 0.0%

— GLOBAL BLOOD THERAPEUTICS IN 3.3%

Value ($000) $36,154 Shares 655,676 Est. Cost $61.75 Unrealized —

— BIOHAVEN PHARMACTL HLDG CO L 2.5%

Value ($000) $28,279 Shares 435,000 Est. Cost $46.07 Unrealized —

VCEL VERICEL CORP 2.5%

Value ($000) $27,439 Shares 1,480,787 Est. Cost $13.53 Unrealized +22.3%

GKOS GLAUKOS CORP 2.0%

Value ($000) $22,091 Shares 446,097 Est. Cost $37.23 Unrealized +18.0%

GERN GERON CORP 1.5%

Value ($000) $16,853 Shares 9,685,528 Est. Cost $1.49 Unrealized +23.7%

PRTA PROTHENA CORP PLC 1.4%

Value ($000) $15,469 Shares 1,548,479 Est. Cost $10.02 Unrealized +20.1%

SGMO SANGAMO THERAPEUTICS INC 1.4%

Value ($000) $15,023 Shares 1,589,724 Est. Cost $8.53 Unrealized +26.8%

— CHEMOCENTRYX INC 1.2%

Value ($000) $13,877 Shares 253,230 Est. Cost $54.80 Unrealized —

— TRANSLATE BIO INC 1.2%

Value ($000) $12,839 Shares 943,339 Est. Cost $13.61 Unrealized —

ALLO ALLOGENE THERAPEUTICS INC 1.1%

Value ($000) $12,400 Shares 328,817 Est. Cost $37.70 Unrealized 0.0%

— INTERSECT ENT INC 1.1%

Value ($000) $12,199 Shares 747,926 Est. Cost $16.31 Unrealized —

IVA INVENTIVA SA 1.1%

Value ($000) $11,813 Shares 999,422 Est. Cost $11.82 Unrealized —

PBYI PUMA BIOTECHNOLOGY INC 1.0%

Value ($000) $11,120 Shares 1,102,073 Est. Cost $10.20 Unrealized -0.1%

— CALITHERA BIOSCIENCES INC 0.9%

Value ($000) $10,069 Shares 2,918,581 Est. Cost $4.87 Unrealized —

— KADMON HLDGS INC 0.9%

Value ($000) $9,800 Shares 2,500,000 Est. Cost $4.24 Unrealized —

VRAYQ VIEWRAY INC 0.8%

Value ($000) $9,295 Shares 2,655,763 Est. Cost $3.08 Unrealized -9.6%

LNTH LANTHEUS HLDGS INC 0.7%

Value ($000) $7,535 Shares 594,750 Est. Cost $13.71 Unrealized 0.0%

LQDA LIQUIDIA TECHNOLOGIES INC 0.5%

Value ($000) $5,853 Shares 1,189,607 Est. Cost $4.01 Unrealized +44.2%

CYTK CYTOKINETICS INC 0.5%

Value ($000) $5,477 Shares 253,000 Est. Cost $18.91 Unrealized +23.7%

— ABEONA THERAPEUTICS INC 0.4%

Value ($000) $3,971 Shares 3,892,921 Est. Cost $2.82 Unrealized —

— MILLENDO THERAPEUTICS INC 0.2%

Value ($000) $1,920 Shares 1,177,900 Est. Cost $7.64 Unrealized —

— OYSTER PT PHARMA INC 0.1%

Value ($000) $1,480 Shares 70,121 Est. Cost $28.88 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
IOVA	IOVANCE BIOTHERAPEUTICS INC	3,876,600	$127,618	11.5%	$18.64	+64.5%	COM	462260100
—	SAGE THERAPEUTICS INC	1,966,688	$120,204	10.8%	$46.88	—	COM	78667J108
ACAD	ACADIA PHARMACEUTICALS INC	1,921,563	$79,264	7.1%	$30.25	+42.7%	COM	004225108
—	ARENA PHARMACEUTICALS INC	996,898	$74,558	6.7%	$56.72	—	COM NEW	040047607
—	ZYMEWORKS INC	1,567,900	$73,033	6.6%	$8101.10	—	COM	98985W102
UTHR	UNITED THERAPEUTICS CORP DEL	640,773	$64,718	5.8%	$85.83	+27.8%	COM	91307C102
—	CONSTELLATION PHARMCETICLS I	2,861,924	$57,983	5.2%	$35.95	—	COM	210373106
CYTK	CYTOKINETICS INC	2,549,525	$55,197	5.0%	$18.91	+23.7%	COM NEW	23282W605
—	GW PHARMACEUTICALS PLC	520,232	$50,645	4.6%	$93.52	—	ADS	36197T103
TGTX	TG THERAPEUTICS INC	1,600,000	$42,816	3.9%	$9.56	+140.7%	COM	88322Q108
MGNX	MACROGENICS INC	1,510,215	$38,042	3.4%	$17.37	+57.2%	COM	556099109
AUPH	AURINIA PHARMACEUTICALS INC	2,485,327	$36,609	3.3%	$14.49	0.0%	COM	05156V102
—	GLOBAL BLOOD THERAPEUTICS IN	655,676	$36,154	3.3%	$61.75	—	COM	37890U108
—	BIOHAVEN PHARMACTL HLDG CO L	435,000	$28,279	2.5%	$46.07	—	COM	G11196105
VCEL	VERICEL CORP	1,480,787	$27,439	2.5%	$13.53	+22.3%	COM	92346J108
GKOS	GLAUKOS CORP	446,097	$22,091	2.0%	$37.23	+18.0%	COM	377322102
GERN	GERON CORP	9,685,528	$16,853	1.5%	$1.49	+23.7%	COM	374163103
PRTA	PROTHENA CORP PLC	1,548,479	$15,469	1.4%	$10.02	+20.1%	SHS	G72800108
SGMO	SANGAMO THERAPEUTICS INC	1,589,724	$15,023	1.4%	$8.53	+26.8%	COM	800677106
—	CHEMOCENTRYX INC	253,230	$13,877	1.2%	$54.80	—	COM	16383L106
—	TRANSLATE BIO INC	943,339	$12,839	1.2%	$13.61	—	COM	89374L104
ALLO	ALLOGENE THERAPEUTICS INC	328,817	$12,400	1.1%	$37.70	0.0%	COM	019770106
—	INTERSECT ENT INC	747,926	$12,199	1.1%	$16.31	—	COM	46071F103
IVA	INVENTIVA SA	999,422	$11,813	1.1%	$11.82	—	ADS	46124U107
PBYI	PUMA BIOTECHNOLOGY INC	1,102,073	$11,120	1.0%	$10.20	-0.1%	COM	74587V107
—	CALITHERA BIOSCIENCES INC	2,918,581	$10,069	0.9%	$4.87	—	COM	13089P101
—	KADMON HLDGS INC	2,500,000	$9,800	0.9%	$4.24	—	COM	48283N106
VRAYQ	VIEWRAY INC	2,655,763	$9,295	0.8%	$3.08	-9.6%	COM	92672L107
LNTH	LANTHEUS HLDGS INC	594,750	$7,535	0.7%	$13.71	0.0%	COM	516544103
LQDA	LIQUIDIA TECHNOLOGIES INC	1,189,607	$5,853	0.5%	$4.01	+44.2%	COM	53635D202
CYTK	CYTOKINETICS INC	253,000	$5,477	0.5%	$18.91	+23.7%	Put	23282W605
—	ABEONA THERAPEUTICS INC	3,892,921	$3,971	0.4%	$2.82	—	COM	00289Y107
—	MILLENDO THERAPEUTICS INC	1,177,900	$1,920	0.2%	$7.64	—	COM	60040X103
—	OYSTER PT PHARMA INC	70,121	$1,480	0.1%	$28.88	—	COM	69242L106