GREAT POINT PARTNERS LLC Quant / Systematic

CIK: 0001281446 · Show all filings

Period: Q3 2021 (← Previous) (Next →)

Filing Date: Nov 15, 2021

Total Value ($000): $429,472 (100.0% shares, 0.0% debt)

Holdings (36)

EXEL EXELIXIS INC 7.5%

Value ($000) $32,239 Shares 1,525,000 Est. Cost $21.82 Unrealized -14.9%

— ARENA PHARMACEUTICALS INC 7.4%

Value ($000) $31,601 Shares 530,670 Est. Cost $60.39 Unrealized —

— KADMON HLDGS INC 6.8%

Value ($000) $29,396 Shares 3,375,000 Est. Cost $4.16 Unrealized —

BCAB BIOATLA INC 5.8%

Value ($000) $24,847 Shares 844,002 Est. Cost $38.96 Unrealized 0.0%

RCKT ROCKET PHARMACEUTICALS INC 5.3%

Value ($000) $22,866 Shares 765,000 Est. Cost $38.30 Unrealized -5.0%

MGNX MACROGENICS INC 4.9%

Value ($000) $20,940 Shares 1,000,000 Est. Cost $18.17 Unrealized +32.6%

— DICERNA PHARMACEUTICALS INC 3.8%

Value ($000) $16,128 Shares 799,999 Est. Cost $20.16 Unrealized —

UTHR UNITED THERAPEUTICS CORP DEL 3.7%

Value ($000) $15,997 Shares 86,667 Est. Cost $100.63 Unrealized +95.7%

VRTX VERTEX PHARMACEUTICALS INC 3.6%

Value ($000) $15,418 Shares 85,000 Est. Cost $195.24 Unrealized 0.0%

TVTX TRAVERE THERAPEUTICS INC 3.5%

Value ($000) $15,156 Shares 625,000 Est. Cost $24.05 Unrealized -23.6%

ANAB ANAPTYSBIO INC 3.5%

Value ($000) $14,904 Shares 549,545 Est. Cost $24.35 Unrealized +4.2%

CYTK CYTOKINETICS INC 3.3%

Value ($000) $13,990 Shares 391,429 Est. Cost $29.44 Unrealized 0.0%

BIIB BIOGEN INC 3.1%

Value ($000) $13,442 Shares 47,500 Est. Cost $288.02 Unrealized +13.8%

URGN UROGEN PHARMA LTD 2.9%

Value ($000) $12,615 Shares 750,000 Est. Cost $15.85 Unrealized 0.0%

DYN DYNE THERAPEUTICS INC 2.8%

Value ($000) $12,099 Shares 745,000 Est. Cost $18.70 Unrealized -5.2%

— SAGE THERAPEUTICS INC 2.8%

Value ($000) $11,920 Shares 269,010 Est. Cost $46.70 Unrealized —

XENE XENON PHARMACEUTICALS INC 2.5%

Value ($000) $10,696 Shares 700,000 Est. Cost $17.38 Unrealized 0.0%

— TRICIDA INC 2.1%

Value ($000) $9,159 Shares 1,974,000 Est. Cost $4.49 Unrealized —

PBYI PUMA BIOTECHNOLOGY INC 2.1%

Value ($000) $9,113 Shares 1,300,000 Est. Cost $10.19 Unrealized -26.5%

OLMA OLEMA PHARMACEUTICALS INC 2.1%

Value ($000) $9,070 Shares 329,086 Est. Cost $28.46 Unrealized -5.1%

— NEKTAR THERAPEUTICS 2.1%

Value ($000) $9,064 Shares 504,691 Est. Cost $17.96 Unrealized —

ACRS ACLARIS THERAPEUTICS INC 2.1%

Value ($000) $9,000 Shares 500,000 Est. Cost $16.03 Unrealized 0.0%

RFL RAFAEL HLDGS INC 2.0%

Value ($000) $8,780 Shares 285,714 Est. Cost $45.91 Unrealized 0.0%

— MAGENTA THERAPEUTICS INC 2.0%

Value ($000) $8,518 Shares 1,170,000 Est. Cost $9.65 Unrealized —

CTMX CYTOMX THERAPEUTICS INC 1.8%

Value ($000) $7,635 Shares 1,500,000 Est. Cost $6.98 Unrealized -23.3%

— RIGEL PHARMACEUTICALS INC 1.7%

Value ($000) $7,187 Shares 1,980,000 Est. Cost $4.17 Unrealized —

— AEGLEA BIOTHERAPEUTICS INC 1.7%

Value ($000) $7,155 Shares 900,000 Est. Cost $7.50 Unrealized —

PHAT PHATHOM PHARMACEUTICALS INC 1.7%

Value ($000) $7,090 Shares 220,863 Est. Cost $33.23 Unrealized 0.0%

APLS APELLIS PHARMACEUTICALS INC 1.5%

Value ($000) $6,592 Shares 200,000 Est. Cost — Unrealized —

— KINIKSA PHARMACEUTICALS LTD 1.3%

Value ($000) $5,467 Shares 480,000 Est. Cost $11.39 Unrealized —

PCVX VAXCYTE INC 0.6%

Value ($000) $2,488 Shares 98,061 Est. Cost $24.24 Unrealized 0.0%

— REPARE THERAPEUTICS INC 0.6%

Value ($000) $2,444 Shares 93,137 Est. Cost $31.18 Unrealized —

COLL COLLEGIUM PHARMACEUTICAL INC 0.6%

Value ($000) $2,395 Shares 121,342 Est. Cost $21.69 Unrealized -0.3%

FOLD AMICUS THERAPEUTICS INC 0.6%

Value ($000) $2,378 Shares 249,000 Est. Cost $9.76 Unrealized +4.8%

IFRX INFLARX NV 0.3%

Value ($000) $1,429 Shares 551,918 Est. Cost $5.12 Unrealized -48.6%

PRQR PROQR THRAPEUTICS N V 0.1%

Value ($000) $254 Shares 30,336 Est. Cost $6.53 Unrealized 0.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
EXEL	EXELIXIS INC	1,525,000	$32,239	7.5%	$21.82	-14.9%	COM	30161Q104
—	ARENA PHARMACEUTICALS INC	530,670	$31,601	7.4%	$60.39	—	COM NEW	040047607
—	KADMON HLDGS INC	3,375,000	$29,396	6.8%	$4.16	—	COM	48283N106
BCAB	BIOATLA INC	844,002	$24,847	5.8%	$38.96	0.0%	COM	09077B104
RCKT	ROCKET PHARMACEUTICALS INC	765,000	$22,866	5.3%	$38.30	-5.0%	COM	77313F106
MGNX	MACROGENICS INC	1,000,000	$20,940	4.9%	$18.17	+32.6%	COM	556099109
—	DICERNA PHARMACEUTICALS INC	799,999	$16,128	3.8%	$20.16	—	COM	253031108
UTHR	UNITED THERAPEUTICS CORP DEL	86,667	$15,997	3.7%	$100.63	+95.7%	COM	91307C102
VRTX	VERTEX PHARMACEUTICALS INC	85,000	$15,418	3.6%	$195.24	0.0%	COM	92532F100
TVTX	TRAVERE THERAPEUTICS INC	625,000	$15,156	3.5%	$24.05	-23.6%	COM	89422G107
ANAB	ANAPTYSBIO INC	549,545	$14,904	3.5%	$24.35	+4.2%	COM	032724106
CYTK	CYTOKINETICS INC	391,429	$13,990	3.3%	$29.44	0.0%	COM NEW	23282W605
BIIB	BIOGEN INC	47,500	$13,442	3.1%	$288.02	+13.8%	COM	09062X103
URGN	UROGEN PHARMA LTD	750,000	$12,615	2.9%	$15.85	0.0%	COM	M96088105
DYN	DYNE THERAPEUTICS INC	745,000	$12,099	2.8%	$18.70	-5.2%	COM	26818M108
—	SAGE THERAPEUTICS INC	269,010	$11,920	2.8%	$46.70	—	COM	78667J108
XENE	XENON PHARMACEUTICALS INC	700,000	$10,696	2.5%	$17.38	0.0%	COM	98420N105
—	TRICIDA INC	1,974,000	$9,159	2.1%	$4.49	—	COM	89610F101
PBYI	PUMA BIOTECHNOLOGY INC	1,300,000	$9,113	2.1%	$10.19	-26.5%	COM	74587V107
OLMA	OLEMA PHARMACEUTICALS INC	329,086	$9,070	2.1%	$28.46	-5.1%	COM	68062P106
—	NEKTAR THERAPEUTICS	504,691	$9,064	2.1%	$17.96	—	COM	640268108
ACRS	ACLARIS THERAPEUTICS INC	500,000	$9,000	2.1%	$16.03	0.0%	COM	00461U105
RFL	RAFAEL HLDGS INC	285,714	$8,780	2.0%	$45.91	0.0%	COM CL B	75062E106
—	MAGENTA THERAPEUTICS INC	1,170,000	$8,518	2.0%	$9.65	—	COM	55910K108
CTMX	CYTOMX THERAPEUTICS INC	1,500,000	$7,635	1.8%	$6.98	-23.3%	COM	23284F105
—	RIGEL PHARMACEUTICALS INC	1,980,000	$7,187	1.7%	$4.17	—	COM NEW	766559603
—	AEGLEA BIOTHERAPEUTICS INC	900,000	$7,155	1.7%	$7.50	—	COM	00773J103
PHAT	PHATHOM PHARMACEUTICALS INC	220,863	$7,090	1.7%	$33.23	0.0%	COM	71722W107
APLS	APELLIS PHARMACEUTICALS INC	200,000	$6,592	1.5%	—	—	Call	03753U106
—	KINIKSA PHARMACEUTICALS LTD	480,000	$5,467	1.3%	$11.39	—	COM CL A	G5269C101
PCVX	VAXCYTE INC	98,061	$2,488	0.6%	$24.24	0.0%	COM	92243G108
—	REPARE THERAPEUTICS INC	93,137	$2,444	0.6%	$31.18	—	COM	760273102
COLL	COLLEGIUM PHARMACEUTICAL INC	121,342	$2,395	0.6%	$21.69	-0.3%	COM	19459J104
FOLD	AMICUS THERAPEUTICS INC	249,000	$2,378	0.6%	$9.76	+4.8%	COM	03152W109
IFRX	INFLARX NV	551,918	$1,429	0.3%	$5.12	-48.6%	COM	N44821101
PRQR	PROQR THRAPEUTICS N V	30,336	$254	0.1%	$6.53	0.0%	SHS EURO	N71542109