Location: Baltimore, MD
CIK: 0001595725 · Show all filings
Period: Q3 2023 (← Previous) (Next →)
Filing Date: Nov 14, 2023
Total Value: $3.733B (99.8% shares, 0.2% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| HUM | HUMANA INC | 436,500 | $212M | 5.7% | $373.18 | +22.4% | COM | 444859102 |
| IMCR | IMMUNOCORE HLDGS PLC | 2,943,710 | $153M | 4.1% | $42.88 | — | ADS | 45258D105 |
| AGL | AGILON HEALTH INC | 8,292,500 | $147M | 3.9% | $33.37 | -45.9% | COM | 00857U107 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,236,000 | $139M | 3.7% | $78.19 | +34.7% | COM | 64125C109 |
| — | BLUEPRINT MEDICINES CORP | 2,685,294 | $135M | 3.6% | $60.87 | — | COM | 09627Y109 |
| ARGX | ARGENX SE | 259,000 | $127M | 3.4% | $153.41 | — | SPONSORED ADR | 04016X101 |
| PEN | PENUMBRA INC | 503,750 | $122M | 3.3% | $176.21 | +57.6% | COM | 70975L107 |
| UNH | UNITEDHEALTH GROUP INC | 230,000 | $116M | 3.1% | $219.29 | +114.3% | COM | 91324P102 |
| EVH | EVOLENT HEALTH INC | 3,865,000 | $105M | 2.8% | $24.98 | +11.3% | CL A | 30050B101 |
| ISRG | INTUITIVE SURGICAL INC | 298,500 | $87.25M | 2.3% | $264.69 | +18.0% | COM NEW | 46120E602 |
| — | KARUNA THERAPEUTICS INC | 505,433 | $85.46M | 2.3% | $94.75 | — | COM | 48576A100 |
| IDXX | IDEXX LABS INC | 194,500 | $85.05M | 2.3% | $335.38 | +48.7% | COM | 45168D104 |
| — | SEAGEN INC | 400,200 | $84.9M | 2.3% | $158.76 | — | COM | 81181C104 |
| WST | WEST PHARMACEUTICAL SVSC INC | 202,000 | $75.79M | 2.0% | $294.97 | +30.3% | COM | 955306105 |
| — | AKERO THERAPEUTICS INC | 1,419,150 | $71.78M | 1.9% | $30.42 | — | COM | 00973Y108 |
| EXAS | EXACT SCIENCES CORP | 1,018,250 | $69.47M | 1.9% | $54.17 | +56.6% | COM | 30063P105 |
| AGIO | AGIOS PHARMACEUTICALS INC | 2,710,061 | $67.07M | 1.8% | $40.40 | -34.5% | COM | 00847X104 |
| ALGN | ALIGN TECHNOLOGY INC | 217,000 | $66.25M | 1.8% | $313.91 | +10.1% | COM | 016255101 |
| ACHC | ACADIA HEALTHCARE COMPANY IN | 908,000 | $63.84M | 1.7% | $51.17 | +46.0% | COM | 00404A109 |
| BSX | BOSTON SCIENTIFIC CORP | 1,160,000 | $61.25M | 1.6% | $52.40 | +0.1% | COM | 101137107 |
| PODD | INSULET CORP | 380,000 | $60.61M | 1.6% | $185.50 | +20.7% | COM | 45784P101 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,820,733 | $57.54M | 1.5% | $14.40 | +90.1% | COM | 604749101 |
| — | CEREVEL THERAPEUTICS HLDNG I | 2,529,116 | $55.21M | 1.5% | $24.09 | — | COM | 15678U128 |
| DXCM | DEXCOM INC | 584,000 | $54.49M | 1.5% | $97.26 | +15.9% | COM | 252131107 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1,476,441 | $52.64M | 1.4% | $63.87 | -38.0% | COM | 90400D108 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 279,500 | $49.5M | 1.3% | $99.88 | +91.3% | COM | 02043Q107 |
| — | MIRATI THERAPEUTICS INC | 1,131,207 | $49.28M | 1.3% | $69.12 | — | COM | 60468T105 |
| SRPT | SAREPTA THERAPEUTICS INC | 392,000 | $47.52M | 1.3% | $62.74 | +80.2% | COM | 803607100 |
| EW | EDWARDS LIFESCIENCES CORP | 647,300 | $44.84M | 1.2% | $62.58 | +28.4% | COM | 28176E108 |
| FRPT | FRESHPET INC | 662,500 | $43.65M | 1.2% | $60.72 | +18.1% | COM | 358039105 |
| XENE | XENON PHARMACEUTICALS INC | 1,178,002 | $40.24M | 1.1% | $22.63 | +65.3% | COM | 98420N105 |
| ASND | ASCENDIS PHARMA A/S | 425,500 | $39.84M | 1.1% | $85.24 | — | SPONSORED ADR | 04351P101 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 1,597,123 | $36.61M | 1.0% | $15.80 | +41.8% | COM | 76243J105 |
| PHR | PHREESIA INC | 1,776,391 | $33.18M | 0.9% | $28.24 | -4.7% | COM | 71944F106 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 350,750 | $33.06M | 0.9% | $69.45 | +46.4% | COM | 450056106 |
| PCRX | PACIRA BIOSCIENCES INC | 1,055,500 | $32.38M | 0.9% | $48.41 | -25.5% | COM | 695127100 |
| — | ACCOLADE INC | 2,913,000 | $30.82M | 0.8% | $21.45 | — | COM | 00437E102 |
| LEGN | LEGEND BIOTECH CORP | 458,265 | $30.78M | 0.8% | $40.20 | — | SPONSORED ADS | 52490G102 |
| ZLAB | ZAI LAB LTD | 1,237,023 | $30.07M | 0.8% | $56.75 | — | ADR | 98887Q104 |
| PRTA | PROTHENA CORP PLC | 614,298 | $29.64M | 0.8% | $17.26 | +244.1% | SHS | G72800108 |
| — | HORIZON THERAPEUTICS PUB L | 255,500 | $29.56M | 0.8% | $83.28 | — | SHS | G46188101 |
| — | SHOCKWAVE MED INC | 147,500 | $29.37M | 0.8% | $106.01 | — | COM | 82489T104 |
| — | ABCAM PLC | 1,275,000 | $28.85M | 0.8% | $19.14 | — | ADS | 000380204 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 196,369 | $28.68M | 0.8% | $51.77 | +263.5% | COM | 558868105 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 1,545,016 | $28.29M | 0.8% | $31.47 | -32.8% | COM | 03237H101 |
| ACRS | ACLARIS THERAPEUTICS INC | 3,960,449 | $27.13M | 0.7% | $10.84 | -21.2% | COM | 00461U105 |
| — | DYNAVAX TECHNOLOGIES CORP | 1,813,758 | $26.79M | 0.7% | $7.97 | — | COM NEW | 268158201 |
| XLV | SELECT SECTOR SPDR TR | 200,000 | $25.75M | 0.7% | $128.24 | — | SBI HEALTHCARE | 81369Y209 |
| LFST | LIFESTANCE HEALTH GROUP INC | 3,670,000 | $25.21M | 0.7% | $15.87 | -48.9% | COM | 53228F101 |
| IMVT | IMMUNOVANT INC | 644,344 | $24.74M | 0.7% | $22.60 | 0.0% | COM | 45258J102 |
| — | OLINK HLDG AB | 1,676,500 | $24.73M | 0.7% | $22.11 | — | SPONSORED ADS | 680710100 |
| AZTA | AZENTA INC | 477,500 | $23.97M | 0.6% | $61.29 | -18.0% | COM | 114340102 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 264,500 | $23.4M | 0.6% | $85.70 | +3.8% | COM | 09061G101 |
| — | NEVRO CORP | 1,211,600 | $23.29M | 0.6% | $75.15 | — | COM | 64157F103 |
| IMTX | IMMATICS N.V | 1,875,466 | $21.72M | 0.6% | $9.14 | +30.5% | SHS | N44445109 |
| KYMR | KYMERA THERAPEUTICS INC | 1,504,351 | $20.91M | 0.6% | $30.99 | -35.1% | COM | 501575104 |
| WRBY | WARBY PARKER INC | 1,575,000 | $20.73M | 0.6% | $34.96 | -62.8% | CL A COM | 93403J106 |
| RVMD | REVOLUTION MEDICINES INC | 725,152 | $20.07M | 0.5% | $24.78 | +19.7% | COM | 76155X100 |
| — | MERUS N V | 838,428 | $19.77M | 0.5% | $25.15 | — | COM | N5749R100 |
| AMGN | AMGEN INC | 68,000 | $18.28M | 0.5% | $231.86 | 0.0% | COM | 031162100 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 2,551,226 | $18.06M | 0.5% | $10.39 | -30.8% | COM | 09058V103 |
| IRON | DISC MEDICINE INC | 363,468 | $17.08M | 0.5% | $47.82 | +4.6% | COM | 254604101 |
| TVTX | TRAVERE THERAPEUTICS INC | 1,807,742 | $16.16M | 0.4% | $21.49 | -34.3% | COM | 89422G107 |
| — | INOZYME PHARMA INC | 3,681,174 | $15.46M | 0.4% | $9.28 | — | COM | 45790W108 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 500,101 | $13.76M | 0.4% | $30.25 | +3.6% | COM NEW | 15117B202 |
| FOLD | AMICUS THERAPEUTICS INC | 1,063,806 | $12.94M | 0.3% | $11.48 | +12.4% | COM | 03152W109 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 562,000 | $12.56M | 0.3% | $15.97 | +42.8% | COM | 19459J104 |
| — | IMMUNOGEN INC | 759,365 | $12.05M | 0.3% | $16.31 | — | COM | 45253H101 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 2,812,579 | $11.67M | 0.3% | $6.18 | 0.0% | COM | 00509G209 |
| MLYS | MINERALYS THERAPEUTICS INC | 1,167,492 | $11.1M | 0.3% | $16.83 | -22.5% | COM | 603170101 |
| CMPX | COMPASS THERAPEUTICS INC | 5,513,788 | $10.86M | 0.3% | $3.31 | -25.3% | COM | 20454B104 |
| KRYS | KRYSTAL BIOTECH INC | 90,560 | $10.5M | 0.3% | $114.33 | +6.7% | COM | 501147102 |
| MREO | MEREO BIOPHARMA GROUP PLC | 7,676,481 | $9.903M | 0.3% | $2.58 | — | SPON ADS | 589492107 |
| EDAP | EDAP TMS S A | 1,360,000 | $9.547M | 0.3% | $7.66 | — | SPONSORED ADR | 268311107 |
| INSP | INSPIRE MED SYS INC | 44,500 | $8.831M | 0.2% | $252.20 | 0.0% | COM | 457730109 |
| — | RENEO PHARMACEUTICALS INC | 1,143,185 | $8.705M | 0.2% | $9.31 | — | COM | 75974E103 |
| PLRX | PLIANT THERAPEUTICS INC | 491,221 | $8.518M | 0.2% | $28.47 | -39.1% | COM | 729139105 |
| LUNG | PULMONX CORP | 652,400 | $6.739M | 0.2% | $45.31 | -74.4% | COM | 745848101 |
| — | ICOSAVAX INC | 868,409 | $6.73M | 0.2% | $26.02 | — | COM | 45114M109 |
| SGMT | SAGIMET BIOSCIENCES INC | 738,355 | $6.498M | 0.2% | $13.31 | 0.0% | COM SER A | 786700104 |
| AURA | AURA BIOSCIENCES INC | 722,896 | $6.484M | 0.2% | $17.87 | -39.8% | COM | 05153U107 |
| — | SPRUCE BIOSCIENCES INC | 2,728,125 | $6.166M | 0.2% | $15.23 | — | COM | 85209E109 |
| RLAY | RELAY THERAPEUTICS INC | 673,966 | $5.668M | 0.2% | $33.24 | -67.6% | COM | 75943R102 |
| MGNX | MACROGENICS INC | 1,178,796 | $5.493M | 0.1% | $16.87 | -70.5% | COM | 556099109 |
| NVAX | NOVAVAX INC | 647,700 | $4.689M | 0.1% | $37.34 | -78.6% | COM NEW | 670002401 |
| — | MERSANA THERAPEUTICS INC | 3,403,133 | $4.322M | 0.1% | $13.04 | — | COM | 59045L106 |
| CYTK | CYTOKINETICS INC | 134,252 | $3.955M | 0.1% | $41.02 | -18.8% | COM NEW | 23282W605 |
| AUPH | AURINIA PHARMACEUTICALS INC | 479,540 | $3.726M | 0.1% | $13.26 | -26.3% | COM | 05156V102 |
| — | GOSSAMER BIO INC | 9,573,000 | $3.708M | 0.1% | $1.01 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| FULC | FULCRUM THERAPEUTICS INC | 727,673 | $3.231M | 0.1% | $14.24 | -69.3% | COM | 359616109 |
| HCAT | HEALTH CATALYST INC | 307,500 | $3.112M | 0.1% | $33.08 | -63.9% | COM | 42225T107 |
| XLO | XILIO THERAPEUTICS INC | 1,440,759 | $3.04M | 0.1% | $14.70 | -81.9% | COM | 98422T100 |
| GOSS | GOSSAMER BIO INC | 3,266,960 | $2.721M | 0.1% | $2.62 | -56.0% | COM | 38341P102 |
| BEAM | BEAM THERAPEUTICS INC | 111,430 | $2.68M | 0.1% | $39.75 | -32.6% | COM | 07373V105 |
| — | TRAVERE THERAPEUTICS INC | 3,250,000 | $2.677M | 0.1% | $0.79 | — | NOTE 2.500% 9/1 | 761299AB2 |
| — | VIGIL NEUROSCIENCE INC | 471,958 | $2.544M | 0.1% | $7.03 | — | COM | 92673K108 |
| BMEA | BIOMEA FUSION INC | 181,147 | $2.493M | 0.1% | $15.37 | +17.3% | COM | 09077A106 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 2,787,845 | $2.175M | 0.1% | $7.10 | — | SPONDS ADR | 00653A107 |
| — | ESSA PHARMA INC | 677,005 | $2.092M | 0.1% | $22.67 | — | COM NEW | 29668H708 |
| — | APPLIED THERAPEUTICS INC | 808,809 | $2.014M | 0.1% | $23.69 | — | COM | 03828A101 |
| SYRE | AEGLEA BIOTHERAPEUTICS INC | 136,556 | $1.673M | 0.0% | $13.22 | 0.0% | COM NEW | 00773J202 |
| — | NEUROCRINE BIOSCIENCES INC | 1,000,000 | $1.498M | 0.0% | $1.45 | — | NOTE 2.250% 5/1 | 64125CAD1 |
| CYPH | LEAP THERAPEUTICS INC | 1,074,517 | $1.483M | 0.0% | $5.02 | -53.7% | COM NEW | 52187K200 |
| — | ACELYRIN INC | 141,876 | $1.443M | 0.0% | $20.90 | — | COM | 00445A100 |
| FATE | FATE THERAPEUTICS INC | 612,215 | $1.298M | 0.0% | $21.03 | -84.2% | COM | 31189P102 |
| CGEN | COMPUGEN LTD | 1,289,990 | $1.2M | 0.0% | $6.12 | -82.0% | ORD | M25722105 |
| — | THESEUS PHARMACEUTICALS INC | 437,329 | $1.176M | 0.0% | $12.68 | — | COM | 88369M101 |
| DSGN | DESIGN THERAPEUTICS INC | 460,391 | $1.087M | 0.0% | $26.33 | -82.3% | COM | 25056L103 |
| — | VINCERX PHARMA INC | 891,719 | $901K | 0.0% | $12.19 | — | COM NEW | 92731L106 |
| — | KINNATE BIOPHARMA INC | 405,811 | $568K | 0.0% | $24.53 | — | COM | 49705R105 |
| — | NEVRO CORP | 500,000 | $472K | 0.0% | $1.37 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| NKTX | NKARTA INC | 331,571 | $461K | 0.0% | $26.66 | -92.9% | COM | 65487U108 |
| CRVO | CERVOMED INC | 80,033 | $370K | 0.0% | $5.04 | 0.0% | COM | 15713L109 |
| — | INVITAE CORP | 585,659 | $354K | 0.0% | $19.23 | — | COM | 46185L103 |
| TLPH | ACELRX PHARMACEUTICALS INC | 316,460 | $184K | 0.0% | $2.81 | -66.0% | COM NEW | 00444T209 |
| — | TEMPEST THERAPEUTICS INC | 536,214 | $163K | 0.0% | $7.50 | — | COM | 87978U108 |
| — | ATRECA INC | 362,530 | $94,620 | 0.0% | $13.90 | — | CL A COM | 04965G109 |
| SPRO | SPERO THERAPEUTICS INC | 57,373 | $69,421 | 0.0% | $11.75 | -88.2% | COM | 84833T103 |
| — | GAMIDA CELL LTD | 52,015 | $53,575 | 0.0% | $3.36 | — | SHS | M47364100 |
| — | NUVATION BIO INC | 134,028 | $13,403 | 0.0% | $2.67 | — | *W EXP 07/07/202 | 67080N119 |