Location: Baltimore, MD
CIK: 0001595725 · Show all filings
Period: Q2 2023 (← Previous) (Next →)
Filing Date: Aug 14, 2023
Total Value: $4.203B (99.8% shares, 0.2% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| HUM | HUMANA INC | 470,000 | $210M | 5.0% | $373.18 | +30.8% | COM | 444859102 |
| IMCR | IMMUNOCORE HLDGS PLC | 3,028,410 | $182M | 4.3% | $42.88 | — | ADS | 45258D105 |
| PODD | INSULET CORP | 559,000 | $161M | 3.8% | $185.50 | +63.7% | COM | 45784P101 |
| AGL | AGILON HEALTH INC | 8,282,500 | $144M | 3.4% | $33.37 | -32.6% | COM | 00857U107 |
| — | BLUEPRINT MEDICINES CORP | 2,186,672 | $138M | 3.3% | $63.29 | — | COM | 09627Y109 |
| ARGX | ARGENX SE | 350,000 | $136M | 3.2% | $153.41 | — | SPONSORED ADR | 04016X101 |
| PEN | PENUMBRA INC | 366,000 | $126M | 3.0% | $138.03 | +122.5% | COM | 70975L107 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,279,500 | $121M | 2.9% | $78.19 | +25.0% | COM | 64125C109 |
| EVH | EVOLENT HEALTH INC | 3,803,500 | $115M | 2.7% | $24.94 | +29.7% | CL A | 30050B101 |
| UNH | UNITEDHEALTH GROUP INC | 230,000 | $111M | 2.6% | $219.29 | +112.0% | COM | 91324P102 |
| — | KARUNA THERAPEUTICS INC | 493,527 | $107M | 2.5% | $92.95 | — | COM | 48576A100 |
| ISRG | INTUITIVE SURGICAL INC | 298,500 | $102M | 2.4% | $264.69 | +14.3% | COM NEW | 46120E602 |
| IDXX | IDEXX LABS INC | 194,500 | $97.68M | 2.3% | $335.38 | +42.9% | COM | 45168D104 |
| EXAS | EXACT SCIENCES CORP | 943,500 | $88.59M | 2.1% | $51.74 | +50.8% | COM | 30063P105 |
| — | CEREVEL THERAPEUTICS HLDNG I | 2,513,916 | $79.92M | 1.9% | $24.09 | — | COM | 15678U128 |
| WST | WEST PHARMACEUTICAL SVSC INC | 202,000 | $77.26M | 1.8% | $294.97 | +20.3% | COM | 955306105 |
| — | SEAGEN INC | 400,200 | $77.02M | 1.8% | $158.76 | — | COM | 81181C104 |
| ALGN | ALIGN TECHNOLOGY INC | 217,000 | $76.74M | 1.8% | $313.91 | +1.4% | COM | 016255101 |
| AGIO | AGIOS PHARMACEUTICALS INC | 2,686,167 | $76.07M | 1.8% | $40.40 | -38.4% | COM | 00847X104 |
| — | AKERO THERAPEUTICS INC | 1,550,754 | $72.4M | 1.7% | $30.42 | — | COM | 00973Y108 |
| ACHC | ACADIA HEALTHCARE COMPANY IN | 908,000 | $72.31M | 1.7% | $51.17 | +41.2% | COM | 00404A109 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 345,000 | $65.53M | 1.6% | $99.88 | +98.5% | COM | 02043Q107 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1,384,269 | $63.86M | 1.5% | $65.48 | -29.2% | COM | 90400D108 |
| DXCM | DEXCOM INC | 490,500 | $63.03M | 1.5% | $94.31 | +28.2% | COM | 252131107 |
| EW | EDWARDS LIFESCIENCES CORP | 645,900 | $60.93M | 1.4% | $62.58 | +38.9% | COM | 28176E108 |
| — | ABCAM PLC | 2,405,000 | $58.85M | 1.4% | $19.14 | — | ADS | 000380204 |
| PRTA | PROTHENA CORP PLC | 753,462 | $51.45M | 1.2% | $17.26 | +273.6% | SHS | G72800108 |
| — | HORIZON THERAPEUTICS PUB L | 495,000 | $50.91M | 1.2% | $83.28 | — | SHS | G46188101 |
| SRPT | SAREPTA THERAPEUTICS INC | 425,000 | $48.67M | 1.2% | $62.74 | +105.3% | COM | 803607100 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,820,733 | $47.1M | 1.1% | $14.40 | +84.7% | COM | 604749101 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 199,218 | $46.02M | 1.1% | $51.77 | +423.1% | COM | 558868105 |
| XENE | XENON PHARMACEUTICALS INC | 1,178,002 | $45.35M | 1.1% | $22.63 | +75.6% | COM | 98420N105 |
| FRPT | FRESHPET INC | 662,500 | $43.6M | 1.0% | $60.72 | +7.9% | COM | 358039105 |
| PCRX | PACIRA BIOSCIENCES INC | 1,035,000 | $41.47M | 1.0% | $48.65 | -15.0% | COM | 695127100 |
| ACRS | ACLARIS THERAPEUTICS INC | 3,961,849 | $41.08M | 1.0% | $10.84 | -16.5% | COM | 00461U105 |
| — | MIRATI THERAPEUTICS INC | 1,121,647 | $40.53M | 1.0% | $69.12 | — | COM | 60468T105 |
| PHR | PHREESIA INC | 1,305,000 | $40.47M | 1.0% | $28.73 | +9.0% | COM | 71944F106 |
| — | ACCOLADE INC | 2,820,000 | $37.99M | 0.9% | $21.81 | — | COM | 00437E102 |
| ASND | ASCENDIS PHARMA A/S | 425,500 | $37.98M | 0.9% | $85.24 | — | SPONSORED ADR | 04351P101 |
| KYMR | KYMERA THERAPEUTICS INC | 1,487,551 | $34.2M | 0.8% | $31.12 | -7.9% | COM | 501575104 |
| ZLAB | ZAI LAB LTD | 1,222,423 | $33.9M | 0.8% | $57.13 | — | ADR | 98887Q104 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 1,544,616 | $33.32M | 0.8% | $31.47 | -14.2% | COM | 03237H101 |
| — | SHOCKWAVE MED INC | 115,100 | $32.85M | 0.8% | $79.81 | — | COM | 82489T104 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 309,450 | $32.28M | 0.8% | $65.15 | +84.3% | COM | 450056106 |
| LEGN | LEGEND BIOTECH CORP | 458,265 | $31.63M | 0.8% | $40.20 | — | SPONSORED ADS | 52490G102 |
| — | OLINK HLDG AB | 1,654,000 | $31.01M | 0.7% | $22.21 | — | SPONSORED ADS | 680710100 |
| — | NEVRO CORP | 1,211,400 | $30.79M | 0.7% | $75.15 | — | COM | 64157F103 |
| IMTX | IMMATICS N.V | 2,536,144 | $29.27M | 0.7% | $9.14 | +2.1% | SHS | N44445109 |
| CNMD | CONMED CORP | 205,000 | $27.86M | 0.7% | $114.00 | +4.3% | COM | 207410101 |
| XLV | SELECT SECTOR SPDR TR | 200,000 | $26.55M | 0.6% | $128.24 | — | SBI HEALTHCARE | 81369Y209 |
| LFST | LIFESTANCE HEALTH GROUP INC | 2,900,000 | $26.48M | 0.6% | $17.93 | -53.6% | COM | 53228F101 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 1,597,123 | $26.34M | 0.6% | $15.80 | +14.3% | COM | 76243J105 |
| TVTX | TRAVERE THERAPEUTICS INC | 1,527,720 | $23.47M | 0.6% | $22.84 | -20.4% | COM | 89422G107 |
| — | DYNAVAX TECHNOLOGIES CORP | 1,813,758 | $23.43M | 0.6% | $7.97 | — | COM NEW | 268158201 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 264,500 | $22.93M | 0.5% | $85.70 | +9.8% | COM | 09061G101 |
| AZTA | AZENTA INC | 469,900 | $21.93M | 0.5% | $61.47 | -28.8% | COM | 114340102 |
| MLYS | MINERALYS THERAPEUTICS INC | 1,167,492 | $19.91M | 0.5% | $16.83 | -11.2% | COM | 603170101 |
| — | INOZYME PHARMA INC | 3,428,084 | $19.09M | 0.5% | $9.66 | — | COM | 45790W108 |
| RVMD | REVOLUTION MEDICINES INC | 702,712 | $18.8M | 0.4% | $24.62 | -0.4% | COM | 76155X100 |
| BMEA | BIOMEA FUSION INC | 836,898 | $18.37M | 0.4% | $15.37 | +103.6% | COM | 09077A106 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 2,497,193 | $17.58M | 0.4% | $10.45 | -23.2% | COM | 09058V103 |
| CMPX | COMPASS THERAPEUTICS INC | 5,513,788 | $17.53M | 0.4% | $3.31 | -5.1% | COM | 20454B104 |
| IRON | DISC MEDICINE INC | 363,468 | $16.14M | 0.4% | $47.82 | -25.8% | COM | 254604101 |
| WRBY | WARBY PARKER INC | 1,325,000 | $15.49M | 0.4% | $39.11 | -70.9% | CL A COM | 93403J106 |
| — | CHINOOK THERAPEUTICS INC | 396,280 | $15.23M | 0.4% | $15.86 | — | COM | 16961L106 |
| CYTK | CYTOKINETICS INC | 447,600 | $14.6M | 0.3% | $41.02 | -9.8% | COM NEW | 23282W605 |
| BSX | BOSTON SCIENTIFIC CORP | 267,500 | $14.47M | 0.3% | $52.23 | 0.0% | COM | 101137107 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 421,615 | $14.31M | 0.3% | $30.05 | +12.2% | COM NEW | 15117B202 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 650,000 | $13.97M | 0.3% | $15.97 | +42.2% | COM | 19459J104 |
| FOLD | AMICUS THERAPEUTICS INC | 1,063,806 | $13.36M | 0.3% | $11.48 | +3.4% | COM | 03152W109 |
| — | MERUS N V | 478,531 | $12.6M | 0.3% | $26.33 | — | COM | N5749R100 |
| AURA | AURA BIOSCIENCES INC | 1,019,757 | $12.59M | 0.3% | $17.87 | -40.2% | COM | 05153U107 |
| HCAT | HEALTH CATALYST INC | 929,900 | $11.62M | 0.3% | $33.08 | -64.0% | COM | 42225T107 |
| — | MERSANA THERAPEUTICS INC | 3,403,133 | $11.2M | 0.3% | $13.04 | — | COM | 59045L106 |
| EDAP | EDAP TMS S A | 1,186,300 | $10.94M | 0.3% | $7.76 | — | SPONSORED ADR | 268311107 |
| BHVN | BIOHAVEN LTD | 401,624 | $9.607M | 0.2% | $12.49 | +37.8% | COM | G1110E107 |
| MREO | MEREO BIOPHARMA GROUP PLC | 7,042,391 | $9.296M | 0.2% | $2.70 | — | SPON ADS | 589492107 |
| PLRX | PLIANT THERAPEUTICS INC | 491,221 | $8.901M | 0.2% | $28.47 | -16.9% | COM | 729139105 |
| — | ICOSAVAX INC | 868,409 | $8.623M | 0.2% | $26.02 | — | COM | 45114M109 |
| LUNG | PULMONX CORP | 652,400 | $8.553M | 0.2% | $45.31 | -73.0% | COM | 745848101 |
| RLAY | RELAY THERAPEUTICS INC | 673,966 | $8.465M | 0.2% | $33.24 | -62.6% | COM | 75943R102 |
| — | RENEO PHARMACEUTICALS INC | 1,143,185 | $7.499M | 0.2% | $9.31 | — | COM | 75974E103 |
| GH | GUARDANT HEALTH INC | 200,000 | $7.16M | 0.2% | $42.73 | -32.8% | COM | 40131M109 |
| ANAB | ANAPTYSBIO INC | 341,637 | $6.949M | 0.2% | $28.23 | -28.2% | COM | 032724106 |
| MGNX | MACROGENICS INC | 1,123,096 | $6.009M | 0.1% | $17.45 | -64.7% | COM | 556099109 |
| — | SPRUCE BIOSCIENCES INC | 2,728,125 | $5.865M | 0.1% | $15.23 | — | COM | 85209E109 |
| NVCR | NOVOCURE LTD | 125,000 | $5.188M | 0.1% | $37.58 | +65.2% | ORD SHS | G6674U108 |
| AUPH | AURINIA PHARMACEUTICALS INC | 479,540 | $4.642M | 0.1% | $13.26 | -21.7% | COM | 05156V102 |
| — | VIGIL NEUROSCIENCE INC | 471,958 | $4.436M | 0.1% | $7.03 | — | COM | 92673K108 |
| KRYS | KRYSTAL BIOTECH INC | 34,901 | $4.097M | 0.1% | $102.10 | 0.0% | COM | 501147102 |
| — | THESEUS PHARMACEUTICALS INC | 437,329 | $4.08M | 0.1% | $12.68 | — | COM | 88369M101 |
| NVAX | NOVAVAX INC | 536,700 | $3.988M | 0.1% | $43.41 | -81.9% | COM NEW | 670002401 |
| — | PARATEK PHARMACEUTICALS INC | 1,734,037 | $3.832M | 0.1% | $6.08 | — | COM | 699374302 |
| XLO | XILIO THERAPEUTICS INC | 1,440,759 | $3.775M | 0.1% | $14.70 | -79.3% | COM | 98422T100 |
| BEAM | BEAM THERAPEUTICS INC | 111,430 | $3.558M | 0.1% | $39.75 | -18.4% | COM | 07373V105 |
| CYPH | LEAP THERAPEUTICS INC | 1,074,517 | $3.363M | 0.1% | $5.02 | 0.0% | COM NEW | 52187K200 |
| — | ACELYRIN INC | 141,876 | $2.965M | 0.1% | $20.90 | — | COM | 00445A100 |
| FATE | FATE THERAPEUTICS INC | 612,215 | $2.914M | 0.1% | $21.03 | -73.8% | COM | 31189P102 |
| DSGN | DESIGN THERAPEUTICS INC | 460,391 | $2.9M | 0.1% | $26.33 | -76.8% | COM | 25056L103 |
| — | GOSSAMER BIO INC | 9,573,000 | $2.889M | 0.1% | $1.01 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| — | TRAVERE THERAPEUTICS INC | 3,250,000 | $2.857M | 0.1% | $0.79 | — | NOTE 2.500% 9/1 | 761299AB2 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 563,233 | $2.844M | 0.1% | $2.04 | 0.0% | COM | 09203E105 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 2,787,845 | $2.579M | 0.1% | $7.10 | — | SPONDS ADR | 00653A107 |
| FULC | FULCRUM THERAPEUTICS INC | 727,673 | $2.401M | 0.1% | $14.24 | -79.4% | COM | 359616109 |
| — | KINNATE BIOPHARMA INC | 746,973 | $2.263M | 0.1% | $24.53 | — | COM | 49705R105 |
| — | IMMUNOGEN INC | 112,620 | $2.125M | 0.1% | $18.87 | — | COM | 45253H101 |
| — | INVITAE CORP | 1,650,495 | $1.865M | 0.0% | $19.23 | — | COM | 46185L103 |
| — | ESSA PHARMA INC | 663,317 | $1.791M | 0.0% | $23.07 | — | COM NEW | 29668H708 |
| — | AEGLEA BIOTHERAPEUTICS INC | 3,413,906 | $1.538M | 0.0% | $4.00 | — | COM | 00773J103 |
| CGEN | COMPUGEN LTD | 1,289,990 | $1.471M | 0.0% | $6.12 | -85.8% | ORD | M25722105 |
| — | GAMIDA CELL LTD | 715,023 | $1.38M | 0.0% | $3.36 | — | SHS | M47364100 |
| GOSS | GOSSAMER BIO INC | 1,100,274 | $1.32M | 0.0% | $5.50 | -77.4% | COM | 38341P102 |
| — | NEUROCRINE BIOSCIENCES INC | 1,000,000 | $1.276M | 0.0% | $1.45 | — | NOTE 2.250% 5/1 | 64125CAD1 |
| — | VINCERX PHARMA INC | 891,719 | $1.159M | 0.0% | $12.19 | — | COM NEW | 92731L106 |
| — | APPLIED THERAPEUTICS INC | 780,791 | $999K | 0.0% | $24.45 | — | COM | 03828A101 |
| SPRO | SPERO THERAPEUTICS INC | 669,533 | $971K | 0.0% | $11.75 | -85.4% | COM | 84833T103 |
| ALT | ALTIMMUNE INC | 223,255 | $788K | 0.0% | $14.76 | -69.6% | COM NEW | 02155H200 |
| NKTX | NKARTA INC | 331,571 | $726K | 0.0% | $26.66 | -83.5% | COM | 65487U108 |
| — | TEMPEST THERAPEUTICS INC | 536,214 | $681K | 0.0% | $7.50 | — | COM | 87978U108 |
| — | NEVRO CORP | 500,000 | $462K | 0.0% | $1.37 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| — | ATRECA INC | 362,530 | $355K | 0.0% | $13.90 | — | CL A COM | 04965G109 |
| TLPH | ACELRX PHARMACEUTICALS INC | 316,460 | $351K | 0.0% | $2.81 | -68.9% | COM NEW | 00444T209 |
| — | NUVATION BIO INC | 134,028 | $22,167 | 0.0% | $2.67 | — | *W EXP 07/07/202 | 67080N119 |