Frazier Life Sciences Management, L.P. Diversified Active

CIK: 0001892134 · Show all filings

Period: Q1 2022 (Next →)

Filing Date: May 16, 2022

Total Value ($000): $1,173,379 (100.0% shares, 0.0% debt)

Holdings (42)

ARQT ARCUTIS BIOTHERAPEUTICS INC 13.8%

Value ($000) $162,443 Shares 8,434,232 Est. Cost $16.92 Unrealized 0.0%

PHAT PHATHOM PHARMACEUTICALS INC 6.8%

Value ($000) $79,311 Shares 5,827,415 Est. Cost $16.15 Unrealized 0.0%

MIRM MIRUM PHARMACEUTICALS INC 6.7%

Value ($000) $78,543 Shares 3,566,912 Est. Cost $20.40 Unrealized 0.0%

— SIERRA ONCOLOGY INC 6.4%

Value ($000) $75,067 Shares 2,342,198 Est. Cost $32.05 Unrealized —

KRYS KRYSTAL BIOTECH INC 4.9%

Value ($000) $57,640 Shares 866,250 Est. Cost $62.42 Unrealized 0.0%

— IMAGO BIOSCIENCES INC 4.9%

Value ($000) $57,256 Shares 2,971,274 Est. Cost $19.27 Unrealized —

PCVX VAXCYTE INC 4.8%

Value ($000) $55,776 Shares 2,309,554 Est. Cost $21.85 Unrealized 0.0%

SNDX SYNDAX PHARMACEUTICALS INC 4.7%

Value ($000) $55,536 Shares 3,195,403 Est. Cost $16.84 Unrealized 0.0%

— CHINOOK THERAPEUTICS INC 3.8%

Value ($000) $44,369 Shares 2,712,041 Est. Cost $16.36 Unrealized —

— IVERIC BIO INC 3.5%

Value ($000) $40,755 Shares 2,421,563 Est. Cost $16.83 Unrealized —

— ALPINE IMMUNE SCIENCES INC 3.2%

Value ($000) $37,546 Shares 4,185,757 Est. Cost $8.97 Unrealized —

VRDN VIRIDIAN THERAPEUTICS INC 2.7%

Value ($000) $32,164 Shares 1,739,530 Est. Cost $19.21 Unrealized 0.0%

CRNX CRINETICS PHARMACEUTICALS IN 2.6%

Value ($000) $31,055 Shares 1,414,823 Est. Cost $20.24 Unrealized 0.0%

BCYC BICYCLE THERAPEUTICS PLC 2.3%

Value ($000) $26,483 Shares 603,521 Est. Cost $43.88 Unrealized —

TARS TARSUS PHARMACEUTICALS INC 2.0%

Value ($000) $23,837 Shares 1,417,157 Est. Cost $18.56 Unrealized 0.0%

KALV KALVISTA PHARMACEUTICALS INC 2.0%

Value ($000) $23,174 Shares 1,572,192 Est. Cost $14.37 Unrealized 0.0%

ANAB ANAPTYSBIO INC 1.9%

Value ($000) $22,259 Shares 899,700 Est. Cost $30.26 Unrealized 0.0%

— GRITSTONE BIO INC 1.8%

Value ($000) $21,578 Shares 5,237,348 Est. Cost $4.12 Unrealized —

COGT COGENT BIOSCIENCES INC 1.7%

Value ($000) $19,862 Shares 2,651,754 Est. Cost $6.96 Unrealized 0.0%

ARVN ARVINAS INC 1.6%

Value ($000) $18,193 Shares 270,331 Est. Cost $68.16 Unrealized 0.0%

— TRICIDA INC 1.5%

Value ($000) $17,115 Shares 2,082,093 Est. Cost $8.22 Unrealized —

SLN SILENCE THERAPEUTICS PLC 1.4%

Value ($000) $16,742 Shares 881,173 Est. Cost $19.00 Unrealized —

— MERUS N V 1.4%

Value ($000) $16,630 Shares 628,979 Est. Cost $26.44 Unrealized —

AUTL AUTOLUS THERAPEUTICS PLC 1.3%

Value ($000) $15,624 Shares 3,746,857 Est. Cost $4.17 Unrealized —

— PASSAGE BIO INC 1.3%

Value ($000) $15,529 Shares 5,009,219 Est. Cost $3.10 Unrealized —

— PARDES BIOSCIENCES INC 1.3%

Value ($000) $15,025 Shares 2,081,007 Est. Cost $7.22 Unrealized —

— FRAZIER LIFESCIENCES ACQU CO 1.3%

Value ($000) $14,995 Shares 1,501,000 Est. Cost $9.99 Unrealized —

NTLA INTELLIA THERAPEUTICS INC 1.3%

Value ($000) $14,802 Shares 203,684 Est. Cost $84.72 Unrealized 0.0%

— SUTRO BIOPHARMA INC 1.2%

Value ($000) $14,603 Shares 1,776,479 Est. Cost $8.22 Unrealized —

TYRA TYRA BIOSCIENCES INC 1.2%

Value ($000) $14,206 Shares 1,327,665 Est. Cost $11.87 Unrealized 0.0%

REPL REPLIMUNE GROUP INC 1.0%

Value ($000) $12,171 Shares 716,762 Est. Cost $18.87 Unrealized 0.0%

— GRACELL BIOTECHNOLOGIES INC 0.7%

Value ($000) $8,029 Shares 3,445,973 Est. Cost $2.33 Unrealized —

ACRS ACLARIS THERAPEUTICS INC 0.6%

Value ($000) $7,040 Shares 408,329 Est. Cost $13.64 Unrealized 0.0%

— AVADEL PHARMACEUTICALS PLC 0.6%

Value ($000) $6,501 Shares 951,814 Est. Cost $6.83 Unrealized —

— MOLECULAR TEMPLATES INC 0.4%

Value ($000) $4,740 Shares 1,374,047 Est. Cost $3.45 Unrealized —

— ESSA PHARMA INC 0.4%

Value ($000) $4,282 Shares 692,910 Est. Cost $6.18 Unrealized —

— APTINYX INC 0.4%

Value ($000) $4,275 Shares 1,883,244 Est. Cost $2.27 Unrealized —

IMVT IMMUNOVANT INC 0.3%

Value ($000) $3,228 Shares 585,759 Est. Cost $6.23 Unrealized 0.0%

SRRK SCHOLAR ROCK HLDG CORP 0.2%

Value ($000) $2,011 Shares 156,000 Est. Cost $17.08 Unrealized 0.0%

— CEREVEL THERAPEUTICS HLDNG I 0.2%

Value ($000) $1,955 Shares 55,835 Est. Cost $35.01 Unrealized —

— EPIZYME INC 0.1%

Value ($000) $850 Shares 739,369 Est. Cost $1.15 Unrealized —

— NABRIVA THERAPEUTICS PLC 0.0%

Value ($000) $179 Shares 425,650 Est. Cost $0.42 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ARQT	ARCUTIS BIOTHERAPEUTICS INC	8,434,232	$162,443	13.8%	$16.92	0.0%	COM	03969K108
PHAT	PHATHOM PHARMACEUTICALS INC	5,827,415	$79,311	6.8%	$16.15	0.0%	COM	71722W107
MIRM	MIRUM PHARMACEUTICALS INC	3,566,912	$78,543	6.7%	$20.40	0.0%	COM	604749101
—	SIERRA ONCOLOGY INC	2,342,198	$75,067	6.4%	$32.05	—	COM NEW	82640U404
KRYS	KRYSTAL BIOTECH INC	866,250	$57,640	4.9%	$62.42	0.0%	COM	501147102
—	IMAGO BIOSCIENCES INC	2,971,274	$57,256	4.9%	$19.27	—	COM	45250K107
PCVX	VAXCYTE INC	2,309,554	$55,776	4.8%	$21.85	0.0%	COM	92243G108
SNDX	SYNDAX PHARMACEUTICALS INC	3,195,403	$55,536	4.7%	$16.84	0.0%	COM	87164F105
—	CHINOOK THERAPEUTICS INC	2,712,041	$44,369	3.8%	$16.36	—	COM	16961L106
—	IVERIC BIO INC	2,421,563	$40,755	3.5%	$16.83	—	COM	46583P102
—	ALPINE IMMUNE SCIENCES INC	4,185,757	$37,546	3.2%	$8.97	—	COM	02083G100
VRDN	VIRIDIAN THERAPEUTICS INC	1,739,530	$32,164	2.7%	$19.21	0.0%	COM	92790C104
CRNX	CRINETICS PHARMACEUTICALS IN	1,414,823	$31,055	2.6%	$20.24	0.0%	COM	22663K107
BCYC	BICYCLE THERAPEUTICS PLC	603,521	$26,483	2.3%	$43.88	—	SPONSORED ADS	088786108
TARS	TARSUS PHARMACEUTICALS INC	1,417,157	$23,837	2.0%	$18.56	0.0%	COM	87650L103
KALV	KALVISTA PHARMACEUTICALS INC	1,572,192	$23,174	2.0%	$14.37	0.0%	COM	483497103
ANAB	ANAPTYSBIO INC	899,700	$22,259	1.9%	$30.26	0.0%	COM	032724106
—	GRITSTONE BIO INC	5,237,348	$21,578	1.8%	$4.12	—	COM	39868T105
COGT	COGENT BIOSCIENCES INC	2,651,754	$19,862	1.7%	$6.96	0.0%	COM	19240Q201
ARVN	ARVINAS INC	270,331	$18,193	1.6%	$68.16	0.0%	COM	04335A105
—	TRICIDA INC	2,082,093	$17,115	1.5%	$8.22	—	COM	89610F101
SLN	SILENCE THERAPEUTICS PLC	881,173	$16,742	1.4%	$19.00	—	ADS	82686Q101
—	MERUS N V	628,979	$16,630	1.4%	$26.44	—	COM	N5749R100
AUTL	AUTOLUS THERAPEUTICS PLC	3,746,857	$15,624	1.3%	$4.17	—	SPON ADS	05280R100
—	PASSAGE BIO INC	5,009,219	$15,529	1.3%	$3.10	—	COM	702712100
—	PARDES BIOSCIENCES INC	2,081,007	$15,025	1.3%	$7.22	—	COM	69945Q105
—	FRAZIER LIFESCIENCES ACQU CO	1,501,000	$14,995	1.3%	$9.99	—	UNIT 12/09/2025	G3710A121
NTLA	INTELLIA THERAPEUTICS INC	203,684	$14,802	1.3%	$84.72	0.0%	COM	45826J105
—	SUTRO BIOPHARMA INC	1,776,479	$14,603	1.2%	$8.22	—	COM	869367102
TYRA	TYRA BIOSCIENCES INC	1,327,665	$14,206	1.2%	$11.87	0.0%	COM	90240B106
REPL	REPLIMUNE GROUP INC	716,762	$12,171	1.0%	$18.87	0.0%	COM	76029N106
—	GRACELL BIOTECHNOLOGIES INC	3,445,973	$8,029	0.7%	$2.33	—	SPONSORED ADS	38406L103
ACRS	ACLARIS THERAPEUTICS INC	408,329	$7,040	0.6%	$13.64	0.0%	COM	00461U105
—	AVADEL PHARMACEUTICALS PLC	951,814	$6,501	0.6%	$6.83	—	SPONSORED ADR	05337M104
—	MOLECULAR TEMPLATES INC	1,374,047	$4,740	0.4%	$3.45	—	COM	608550109
—	ESSA PHARMA INC	692,910	$4,282	0.4%	$6.18	—	COM NEW	29668H708
—	APTINYX INC	1,883,244	$4,275	0.4%	$2.27	—	COM	03836N103
IMVT	IMMUNOVANT INC	585,759	$3,228	0.3%	$6.23	0.0%	COM	45258J102
SRRK	SCHOLAR ROCK HLDG CORP	156,000	$2,011	0.2%	$17.08	0.0%	COM	80706P103
—	CEREVEL THERAPEUTICS HLDNG I	55,835	$1,955	0.2%	$35.01	—	COM	15678U128
—	EPIZYME INC	739,369	$850	0.1%	$1.15	—	COM	29428V104
—	NABRIVA THERAPEUTICS PLC	425,650	$179	0.0%	$0.42	—	SHS	G63637113