Frazier Life Sciences Management, L.P. Diversified Active

CIK: 0001892134 · Show all filings

Period: Q2 2022 (← Previous) (Next →)

Filing Date: Aug 10, 2022

Total Value ($000): $1,059,640 (100.0% shares, 0.0% debt)

Holdings (41)

ARQT ARCUTIS BIOTHERAPEUTICS INC 17.0%

Value ($000) $179,733 Shares 8,434,232 Est. Cost $16.92 Unrealized +21.3%

— HILLEVAX INC 9.6%

Value ($000) $101,493 Shares 9,285,682 Est. Cost $10.93 Unrealized —

KRYS KRYSTAL BIOTECH INC 6.8%

Value ($000) $71,924 Shares 1,095,407 Est. Cost $62.37 Unrealized -0.3%

MIRM MIRUM PHARMACEUTICALS INC 6.6%

Value ($000) $69,412 Shares 3,566,912 Est. Cost $20.40 Unrealized +15.6%

— CHINOOK THERAPEUTICS INC 5.9%

Value ($000) $62,877 Shares 3,595,026 Est. Cost $16.64 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 5.8%

Value ($000) $61,480 Shares 3,195,403 Est. Cost $16.84 Unrealized -1.1%

PHAT PHATHOM PHARMACEUTICALS INC 4.6%

Value ($000) $49,183 Shares 5,827,415 Est. Cost $16.15 Unrealized -36.4%

— SIERRA ONCOLOGY INC 4.5%

Value ($000) $47,876 Shares 870,636 Est. Cost $32.05 Unrealized —

— IMAGO BIOSCIENCES INC 3.8%

Value ($000) $39,785 Shares 2,971,274 Est. Cost $19.27 Unrealized —

PCVX VAXCYTE INC 3.7%

Value ($000) $38,894 Shares 1,787,405 Est. Cost $21.85 Unrealized +5.9%

CRNX CRINETICS PHARMACEUTICALS IN 2.5%

Value ($000) $26,386 Shares 1,414,823 Est. Cost $20.24 Unrealized -1.4%

TARS TARSUS PHARMACEUTICALS INC 2.5%

Value ($000) $26,098 Shares 1,787,527 Est. Cost $17.82 Unrealized -15.8%

— ALPINE IMMUNE SCIENCES INC 2.4%

Value ($000) $25,409 Shares 2,985,757 Est. Cost $8.97 Unrealized —

— TRICIDA INC 1.9%

Value ($000) $20,155 Shares 2,082,093 Est. Cost $8.22 Unrealized —

COGT COGENT BIOSCIENCES INC 1.8%

Value ($000) $18,889 Shares 2,094,154 Est. Cost $6.96 Unrealized -2.0%

ANAB ANAPTYSBIO INC 1.7%

Value ($000) $18,264 Shares 899,700 Est. Cost $30.26 Unrealized -26.8%

— GRACELL BIOTECHNOLOGIES INC 1.6%

Value ($000) $17,114 Shares 3,111,551 Est. Cost $2.33 Unrealized —

KALV KALVISTA PHARMACEUTICALS INC 1.5%

Value ($000) $15,470 Shares 1,572,192 Est. Cost $14.37 Unrealized -23.2%

— MERUS N V 1.4%

Value ($000) $15,259 Shares 673,979 Est. Cost $26.19 Unrealized —

— FRAZIER LIFESCIENCES ACQU CO 1.4%

Value ($000) $14,815 Shares 1,501,000 Est. Cost $9.99 Unrealized —

REPL REPLIMUNE GROUP INC 1.3%

Value ($000) $14,094 Shares 806,267 Est. Cost $18.60 Unrealized -11.7%

— GRITSTONE BIO INC 1.2%

Value ($000) $12,674 Shares 5,237,348 Est. Cost $4.12 Unrealized —

ARVN ARVINAS INC 1.1%

Value ($000) $12,010 Shares 285,331 Est. Cost $67.21 Unrealized -25.3%

— PASSAGE BIO INC 1.1%

Value ($000) $11,822 Shares 5,009,219 Est. Cost $3.10 Unrealized —

VRDN VIRIDIAN THERAPEUTICS INC 1.1%

Value ($000) $11,342 Shares 980,302 Est. Cost $19.21 Unrealized -30.1%

AUTL AUTOLUS THERAPEUTICS PLC 1.0%

Value ($000) $10,604 Shares 3,746,857 Est. Cost $4.17 Unrealized —

NTLA INTELLIA THERAPEUTICS INC 1.0%

Value ($000) $10,543 Shares 203,684 Est. Cost $84.72 Unrealized -40.1%

SLN SILENCE THERAPEUTICS PLC 1.0%

Value ($000) $10,442 Shares 881,173 Est. Cost $19.00 Unrealized —

TYRA TYRA BIOSCIENCES INC 0.9%

Value ($000) $9,832 Shares 1,375,065 Est. Cost $11.74 Unrealized -32.1%

— SUTRO BIOPHARMA INC 0.9%

Value ($000) $9,255 Shares 1,776,479 Est. Cost $8.22 Unrealized —

ACRS ACLARIS THERAPEUTICS INC 0.5%

Value ($000) $5,700 Shares 408,329 Est. Cost $13.64 Unrealized +2.7%

— CEREVEL THERAPEUTICS HLDNG I 0.5%

Value ($000) $5,348 Shares 202,260 Est. Cost $28.81 Unrealized —

TRVI TREVI THERAPEUTICS INC 0.3%

Value ($000) $3,292 Shares 1,171,627 Est. Cost $2.46 Unrealized 0.0%

— PARDES BIOSCIENCES INC 0.2%

Value ($000) $2,596 Shares 845,636 Est. Cost $7.22 Unrealized —

IMVT IMMUNOVANT INC 0.2%

Value ($000) $2,284 Shares 585,759 Est. Cost $6.23 Unrealized -30.6%

— ESSA PHARMA INC 0.2%

Value ($000) $2,183 Shares 692,910 Est. Cost $6.18 Unrealized —

— IVERIC BIO INC 0.2%

Value ($000) $1,635 Shares 170,000 Est. Cost $16.83 Unrealized —

— MOLECULAR TEMPLATES INC 0.1%

Value ($000) $1,253 Shares 1,374,047 Est. Cost $3.45 Unrealized —

— EPIZYME INC 0.1%

Value ($000) $1,087 Shares 739,369 Est. Cost $1.15 Unrealized —

— APTINYX INC 0.1%

Value ($000) $1,051 Shares 1,883,244 Est. Cost $2.27 Unrealized —

— NABRIVA THERAPEUTICS PLC 0.0%

Value ($000) $77 Shares 425,650 Est. Cost $0.42 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ARQT	ARCUTIS BIOTHERAPEUTICS INC	8,434,232	$179,733	17.0%	$16.92	+21.3%	COM	03969K108
—	HILLEVAX INC	9,285,682	$101,493	9.6%	$10.93	—	COM	43157M102
KRYS	KRYSTAL BIOTECH INC	1,095,407	$71,924	6.8%	$62.37	-0.3%	COM	501147102
MIRM	MIRUM PHARMACEUTICALS INC	3,566,912	$69,412	6.6%	$20.40	+15.6%	COM	604749101
—	CHINOOK THERAPEUTICS INC	3,595,026	$62,877	5.9%	$16.64	—	COM	16961L106
SNDX	SYNDAX PHARMACEUTICALS INC	3,195,403	$61,480	5.8%	$16.84	-1.1%	COM	87164F105
PHAT	PHATHOM PHARMACEUTICALS INC	5,827,415	$49,183	4.6%	$16.15	-36.4%	COM	71722W107
—	SIERRA ONCOLOGY INC	870,636	$47,876	4.5%	$32.05	—	COM NEW	82640U404
—	IMAGO BIOSCIENCES INC	2,971,274	$39,785	3.8%	$19.27	—	COM	45250K107
PCVX	VAXCYTE INC	1,787,405	$38,894	3.7%	$21.85	+5.9%	COM	92243G108
CRNX	CRINETICS PHARMACEUTICALS IN	1,414,823	$26,386	2.5%	$20.24	-1.4%	COM	22663K107
TARS	TARSUS PHARMACEUTICALS INC	1,787,527	$26,098	2.5%	$17.82	-15.8%	COM	87650L103
—	ALPINE IMMUNE SCIENCES INC	2,985,757	$25,409	2.4%	$8.97	—	COM	02083G100
—	TRICIDA INC	2,082,093	$20,155	1.9%	$8.22	—	COM	89610F101
COGT	COGENT BIOSCIENCES INC	2,094,154	$18,889	1.8%	$6.96	-2.0%	COM	19240Q201
ANAB	ANAPTYSBIO INC	899,700	$18,264	1.7%	$30.26	-26.8%	COM	032724106
—	GRACELL BIOTECHNOLOGIES INC	3,111,551	$17,114	1.6%	$2.33	—	SPONSORED ADS	38406L103
KALV	KALVISTA PHARMACEUTICALS INC	1,572,192	$15,470	1.5%	$14.37	-23.2%	COM	483497103
—	MERUS N V	673,979	$15,259	1.4%	$26.19	—	COM	N5749R100
—	FRAZIER LIFESCIENCES ACQU CO	1,501,000	$14,815	1.4%	$9.99	—	UNIT 12/09/2025	G3710A121
REPL	REPLIMUNE GROUP INC	806,267	$14,094	1.3%	$18.60	-11.7%	COM	76029N106
—	GRITSTONE BIO INC	5,237,348	$12,674	1.2%	$4.12	—	COM	39868T105
ARVN	ARVINAS INC	285,331	$12,010	1.1%	$67.21	-25.3%	COM	04335A105
—	PASSAGE BIO INC	5,009,219	$11,822	1.1%	$3.10	—	COM	702712100
VRDN	VIRIDIAN THERAPEUTICS INC	980,302	$11,342	1.1%	$19.21	-30.1%	COM	92790C104
AUTL	AUTOLUS THERAPEUTICS PLC	3,746,857	$10,604	1.0%	$4.17	—	SPON ADS	05280R100
NTLA	INTELLIA THERAPEUTICS INC	203,684	$10,543	1.0%	$84.72	-40.1%	COM	45826J105
SLN	SILENCE THERAPEUTICS PLC	881,173	$10,442	1.0%	$19.00	—	ADS	82686Q101
TYRA	TYRA BIOSCIENCES INC	1,375,065	$9,832	0.9%	$11.74	-32.1%	COM	90240B106
—	SUTRO BIOPHARMA INC	1,776,479	$9,255	0.9%	$8.22	—	COM	869367102
ACRS	ACLARIS THERAPEUTICS INC	408,329	$5,700	0.5%	$13.64	+2.7%	COM	00461U105
—	CEREVEL THERAPEUTICS HLDNG I	202,260	$5,348	0.5%	$28.81	—	COM	15678U128
TRVI	TREVI THERAPEUTICS INC	1,171,627	$3,292	0.3%	$2.46	0.0%	COM	89532M101
—	PARDES BIOSCIENCES INC	845,636	$2,596	0.2%	$7.22	—	COM	69945Q105
IMVT	IMMUNOVANT INC	585,759	$2,284	0.2%	$6.23	-30.6%	COM	45258J102
—	ESSA PHARMA INC	692,910	$2,183	0.2%	$6.18	—	COM NEW	29668H708
—	IVERIC BIO INC	170,000	$1,635	0.2%	$16.83	—	COM	46583P102
—	MOLECULAR TEMPLATES INC	1,374,047	$1,253	0.1%	$3.45	—	COM	608550109
—	EPIZYME INC	739,369	$1,087	0.1%	$1.15	—	COM	29428V104
—	APTINYX INC	1,883,244	$1,051	0.1%	$2.27	—	COM	03836N103
—	NABRIVA THERAPEUTICS PLC	425,650	$77	0.0%	$0.42	—	SHS	G63637113