CENTURY THERAPEUTICS INC

Ticker: IPSC CUSIP: 15673T100 Class: Common Stock

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

New Positions (7)

Point72 Asset Management, L.P.
Value ($000) $5,931 Shares 5,961,631
ADAGE CAPITAL PARTNERS GP, L.L.C.
Value ($000) $1,829 Shares 1,838,700
Scientech Research LLC
Value ($000) $12 Shares 12,355
SIMPLEX TRADING, LLC
Value ($000) $2 Shares 2,397
ALGERT GLOBAL LLC
Value ($000) $0 Shares 76,800
WELLS FARGO & COMPANY/MN
Value ($000) $0 Shares 40
Smartleaf Asset Management LLC
Value ($000) $0 Shares 1

Increased Positions (8)

DAFNA Capital Management LLC
Value ($000) $2,779 (+227.4%) Shares 2,793,586 (+63.9%)
TWO SIGMA INVESTMENTS, LP
Value ($000) $1,488 (+227.9%) Shares 1,495,916 (+64.1%)
TWO SIGMA ADVISERS, LP
Value ($000) $1,261 (+195.3%) Shares 1,267,700 (+47.8%)
UBS Group AG
Value ($000) $213 (+126940.5%) Shares 214,501 (+63550.1%)
NORTHERN TRUST CORP
Value ($000) $105 (+213.2%) Shares 105,052 (+56.8%)
GEODE CAPITAL MANAGEMENT, LLC
Value ($000) $454 (+104.6%) Shares 456,115 (+2.4%)
JPMORGAN CHASE & CO
Value ($000) $3 (+286.0%) Shares 3,077 (+93.2%)
ACADIAN ASSET MANAGEMENT LLC
Value ($000) $1 (+238.7%) Shares 1,217,103 (+69.1%)

Decreased Positions (14)

RENAISSANCE TECHNOLOGIES LLC
Value ($000) $1,342 (+4.2%) Shares 1,349,200 (-47.8%)
GSA CAPITAL PARTNERS LLP
Value ($000) $0 (+10.0%) Shares 333,199 (-44.8%)
MILLENNIUM MANAGEMENT LLC
Value ($000) $607 (+63.9%) Shares 610,387 (-17.9%)
FMR LLC
Value ($000) $71 (-25.6%) Shares 71,540 (-62.8%)
BARCLAYS PLC
Value ($000) $0 (-100.0%) Shares 1 (-100.0%)
CITADEL ADVISORS LLC
Value ($000) $318 (+76.9%) Shares 319,457 (-11.5%)
SUSQUEHANNA INTERNATIONAL GROUP, LLP
Value ($000) $50 (+47.4%) Shares 50,104 (-26.2%)
XTX Topco Ltd
Value ($000) $15 (+11.1%) Shares 15,333 (-44.4%)
JANE STREET GROUP, LLC
Value ($000) $45 (+53.7%) Shares 45,194 (-23.1%)
CITIGROUP INC
Value ($000) $0 (-99.9%) Shares 1 (-100.0%)
Advisors Asset Management, Inc.
Value ($000) $8 (+97.4%) Shares 8,313 (-1.2%)
BANK OF AMERICA CORP /DE/
Value ($000) $1 (+75.2%) Shares 525 (-12.2%)
BNP PARIBAS ARBITRAGE, SA
Value ($000) $1 (+95.5%) Shares 1,447 (-2.1%)
ROYAL BANK OF CANADA
Value ($000) $0 Shares 69 (-2.8%)

Exited Positions (15)

Bain Capital Life Sciences Investors, LLC
Value ($000) $1,762 Shares 3,538,609
TANG CAPITAL MANAGEMENT LLC
Value ($000) $448 Shares 900,000
Squarepoint Ops LLC
Value ($000) $118 Shares 236,053
GOLDMAN SACHS GROUP INC
Value ($000) $30 Shares 60,682
MARSHALL WACE, LLP
Value ($000) $27 Shares 54,161
Qube Research & Technologies Ltd
Value ($000) $9 Shares 17,501
Tower Research Capital LLC (TRC)
Value ($000) $7 Shares 13,116
Jain Global LLC
Value ($000) $6 Shares 11,241
AQR CAPITAL MANAGEMENT LLC
Value ($000) $5 Shares 10,660
Advisory Services Network, LLC
Value ($000) $0 Shares 407
MORGAN STANLEY
Value ($000) $0 Shares 118
EverSource Wealth Advisors, LLC
Value ($000) $0 Shares 28
HRT FINANCIAL LP
Value ($000) $0 Shares 18,113
IFP Advisors, Inc
Value ($000) $0 Shares 6
CWM, LLC
Value ($000) $0 Shares 254