EcoR1 Capital, LLC Quant / Systematic

CIK: 0001587114 · Show all filings

Period: Q1 2023 (← Previous) (Next →)

Filing Date: May 15, 2023

Total Value ($000): $3,105,402 (100.0% shares, 0.0% debt)

Holdings (58)

PRTA PROTHENA CORP PLC 18.1%
Value ($000) $561,490 Shares 11,584,280 Est. Cost $11.63 Unrealized +354.1%
SRPT SAREPTA THERAPEUTICS INC 13.3%
Value ($000) $413,415 Shares 2,999,453 Est. Cost $76.84 Unrealized +68.8%
APLS APELLIS PHARMACEUTICALS INC 11.6%
Value ($000) $359,591 Shares 5,451,647 Est. Cost $41.28 Unrealized +39.8%
GLPG GALAPAGOS NV 5.3%
Value ($000) $164,013 Shares 4,244,645 Est. Cost $52.43 Unrealized —
ANAB ANAPTYSBIO INC 5.3%
Value ($000) $163,657 Shares 7,521,024 Est. Cost $23.15 Unrealized +5.0%
XNCR XENCOR INC 4.7%
Value ($000) $147,329 Shares 5,282,516 Est. Cost $33.50 Unrealized -8.0%
— MORPHIC HLDG INC 4.7%
Value ($000) $144,800 Shares 3,846,966 Est. Cost $29.75 Unrealized —
RVMD REVOLUTION MEDICINES INC 3.7%
Value ($000) $115,928 Shares 5,352,183 Est. Cost $21.45 Unrealized +14.8%
ACAD ACADIA PHARMACEUTICALS INC 3.6%
Value ($000) $112,760 Shares 5,991,479 Est. Cost $22.11 Unrealized -13.9%
ARVN ARVINAS INC 3.3%
Value ($000) $101,570 Shares 3,717,788 Est. Cost $54.94 Unrealized -42.5%
ZYME ZYMEWORKS INC 2.9%
Value ($000) $91,191 Shares 10,087,473 Est. Cost $7.45 Unrealized +17.1%
— SPRINGWORKS THERAPEUTICS INC 2.9%
Value ($000) $89,066 Shares 3,460,208 Est. Cost $28.53 Unrealized —
KURA KURA ONCOLOGY INC 2.6%
Value ($000) $81,187 Shares 6,638,371 Est. Cost $18.76 Unrealized -33.5%
RLAY RELAY THERAPEUTICS INC 2.2%
Value ($000) $68,578 Shares 4,163,824 Est. Cost $28.03 Unrealized -36.0%
JANX JANUX THERAPEUTICS INC 1.5%
Value ($000) $46,446 Shares 3,838,486 Est. Cost $18.73 Unrealized -11.1%
VYGR VOYAGER THERAPEUTICS INC 1.0%
Value ($000) $29,695 Shares 3,851,507 Est. Cost $3.51 Unrealized —
DYN DYNE THERAPEUTICS INC 0.9%
Value ($000) $26,754 Shares 2,322,384 Est. Cost $11.57 Unrealized +12.2%
— NGM BIOPHARMACEUTICALS INC 0.8%
Value ($000) $26,257 Shares 6,435,518 Est. Cost $5.88 Unrealized —
ALEC ALECTOR INC 0.8%
Value ($000) $25,110 Shares 4,056,548 Est. Cost $19.56 Unrealized -58.4%
KYMR KYMERA THERAPEUTICS INC 0.8%
Value ($000) $23,588 Shares 796,093 Est. Cost $26.36 Unrealized +22.4%
EWTX EDGEWISE THERAPEUTICS INC 0.8%
Value ($000) $23,300 Shares 3,493,194 Est. Cost $18.91 Unrealized -51.0%
NUVB NUVATION BIO INC 0.7%
Value ($000) $23,068 Shares 13,896,543 Est. Cost $11.16 Unrealized -81.8%
ALLO ALLOGENE THERAPEUTICS INC 0.7%
Value ($000) $22,172 Shares 4,488,200 Est. Cost $8.88 Unrealized -27.8%
CNTA CENTESSA PHARMACEUTICALS PLC 0.7%
Value ($000) $21,632 Shares 5,618,779 Est. Cost $4.55 Unrealized —
CRNX CRINETICS PHARMACEUTICALS IN 0.7%
Value ($000) $21,364 Shares 1,330,263 Est. Cost $22.08 Unrealized -16.2%
— GRAPHITE BIO INC 0.7%
Value ($000) $20,919 Shares 8,538,446 Est. Cost $3.82 Unrealized —
AVIR ATEA PHARMACEUTICALS INC 0.7%
Value ($000) $20,719 Shares 6,184,861 Est. Cost $14.25 Unrealized -71.5%
— ADICET BIO INC 0.7%
Value ($000) $20,510 Shares 3,560,700 Est. Cost $8.94 Unrealized —
ORIC ORIC PHARMACEUTICALS INC 0.6%
Value ($000) $19,483 Shares 3,418,068 Est. Cost $30.24 Unrealized -82.7%
TNGX TANGO THERAPEUTICS INC 0.5%
Value ($000) $16,596 Shares 4,201,414 Est. Cost $6.32 Unrealized -8.2%
OVID OVID THERAPEUTICS INC 0.5%
Value ($000) $15,783 Shares 6,117,400 Est. Cost $3.32 Unrealized -28.6%
— CHINOOK THERAPEUTICS INC 0.3%
Value ($000) $10,314 Shares 445,550 Est. Cost $16.36 Unrealized —
— GENERATION BIO CO 0.3%
Value ($000) $8,413 Shares 1,956,579 Est. Cost $4.30 Unrealized —
— POSEIDA THERAPEUTICS INC 0.3%
Value ($000) $8,162 Shares 2,650,000 Est. Cost $3.53 Unrealized —
— THIRD HARMONIC BIO INC 0.2%
Value ($000) $7,425 Shares 1,802,122 Est. Cost $4.12 Unrealized —
PRME PRIME MEDICINE INC 0.2%
Value ($000) $7,380 Shares 600,000 Est. Cost $18.06 Unrealized -9.8%
PRQR PROQR THRAPEUTICS N V 0.2%
Value ($000) $6,183 Shares 2,902,715 Est. Cost $3.06 Unrealized 0.0%
BEAM BEAM THERAPEUTICS INC 0.2%
Value ($000) $6,081 Shares 198,591 Est. Cost $39.47 Unrealized 0.0%
ARQT ARCUTIS BIOTHERAPEUTICS INC 0.1%
Value ($000) $4,569 Shares 415,322 Est. Cost $16.92 Unrealized -14.5%
MGNX MACROGENICS INC 0.1%
Value ($000) $4,440 Shares 619,192 Est. Cost $4.10 Unrealized +46.8%
— ALIGOS THERAPEUTICS INC 0.1%
Value ($000) $3,451 Shares 3,948,360 Est. Cost $2.37 Unrealized —
CGEM CULLINAN ONCOLOGY INC 0.1%
Value ($000) $2,521 Shares 246,410 Est. Cost $11.34 Unrealized -2.8%
— TEMPEST THERAPEUTICS INC 0.1%
Value ($000) $2,393 Shares 1,031,268 Est. Cost $2.15 Unrealized —
BDTX BLACK DIAMOND THERAPEUTICS I 0.1%
Value ($000) $2,251 Shares 1,191,094 Est. Cost $2.18 Unrealized +5.4%
— SURFACE ONCOLOGY INC 0.1%
Value ($000) $2,154 Shares 3,082,959 Est. Cost $2.94 Unrealized —
ERAS ERASCA INC 0.1%
Value ($000) $2,042 Shares 678,441 Est. Cost $20.63 Unrealized -82.4%
— EUCRATES BIOMEDICAL ACQU COR 0.1%
Value ($000) $2,028 Shares 200,000 Est. Cost $9.98 Unrealized —
— HOOKIPA PHARMA INC 0.1%
Value ($000) $1,820 Shares 2,473,489 Est. Cost $2.28 Unrealized —
— NUVATION BIO INC 0.1%
Value ($000) $1,599 Shares 963,333 Est. Cost $10.45 Unrealized —
— GRACELL BIOTECHNOLOGIES INC 0.0%
Value ($000) $1,486 Shares 798,948 Est. Cost $2.66 Unrealized —
NAMSW NEWAMSTERDAM PHARMA COMPANY 0.0%
Value ($000) $884 Shares 66,665 Est. Cost $10.90 Unrealized —
— EUCRATES BIOMEDICAL ACQU COR 0.0%
Value ($000) $676 Shares 66,666 Est. Cost $9.90 Unrealized —
— KRONOS BIO INC 0.0%
Value ($000) $477 Shares 326,780 Est. Cost $29.87 Unrealized —
— SELECTA BIOSCIENCES INC 0.0%
Value ($000) $278 Shares 200,000 Est. Cost $1.31 Unrealized —
— CAREMAX INC 0.0%
Value ($000) $267 Shares 100,000 Est. Cost $12.90 Unrealized —
— CYTEIR THERAPEUTICS INC 0.0%
Value ($000) $80 Shares 43,823 Est. Cost $1.82 Unrealized —
SRZNW SURROZEN INC 0.0%
Value ($000) $40 Shares 66,665 Est. Cost $7.07 Unrealized —
— ITEOS THERAPEUTICS INC 0.0%
Value ($000) $18 Shares 1,300 Est. Cost $21.93 Unrealized —