Location: San Francisco, CA
CIK: 0001587114 · Show all filings
Period: Q4 2022 (← Previous) (Next →)
Filing Date: Feb 14, 2023
Total Value: $3.286B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| PRTA | PROTHENA CORP PLC | 11,584,280 | $698M | 21.2% | $11.63 | +403.3% | SHS | G72800108 |
| SRPT | SAREPTA THERAPEUTICS INC | 2,999,453 | $389M | 11.8% | $76.84 | +50.8% | COM | 803607100 |
| APLS | APELLIS PHARMACEUTICALS INC | 5,183,431 | $268M | 8.2% | $40.43 | +31.2% | COM | 03753U106 |
| ANAB | ANAPTYSBIO INC | 7,521,024 | $233M | 7.1% | $23.15 | +22.0% | COM | 032724106 |
| GLPG | GALAPAGOS NV | 3,730,730 | $166M | 5.0% | $54.33 | — | SPON ADR | 36315X101 |
| XNCR | XENCOR INC | 5,282,516 | $138M | 4.2% | $33.50 | -16.5% | COM | 98401F105 |
| ARVN | ARVINAS INC | 3,123,300 | $107M | 3.3% | $59.39 | -29.2% | COM | 04335A105 |
| RVMD | REVOLUTION MEDICINES INC | 4,458,731 | $106M | 3.2% | $20.81 | +2.2% | COM | 76155X100 |
| — | MORPHIC HLDG INC | 3,951,566 | $106M | 3.2% | $29.75 | — | COM | 61775R105 |
| ACAD | ACADIA PHARMACEUTICALS INC | 5,991,479 | $95.38M | 2.9% | $22.11 | -29.3% | COM | 004225108 |
| — | SPRINGWORKS THERAPEUTICS INC | 3,460,208 | $90M | 2.7% | $28.53 | — | COM | 85205L107 |
| KURA | KURA ONCOLOGY INC | 6,638,371 | $82.38M | 2.5% | $18.76 | -22.5% | COM | 50127T109 |
| ZLAB | ZAI LAB LTD | 2,157,686 | $66.24M | 2.0% | $42.44 | — | ADR | 98887Q104 |
| RLAY | RELAY THERAPEUTICS INC | 4,163,824 | $62.21M | 1.9% | $28.03 | -31.7% | COM | 75943R102 |
| ZYME | ZYMEWORKS DEL INC | 7,568,573 | $59.49M | 1.8% | $7.03 | 0.0% | COM ADDED | 98985Y108 |
| ALEC | ALECTOR INC | 4,056,548 | $37.44M | 1.1% | $19.56 | -55.4% | COM | 014442107 |
| — | NGM BIOPHARMACEUTICALS INC | 6,435,518 | $32.31M | 1.0% | $5.88 | — | COM | 62921N105 |
| — | ADICET BIO INC | 3,560,700 | $31.83M | 1.0% | $8.94 | — | COM | 007002108 |
| EWTX | EDGEWISE THERAPEUTICS INC | 3,493,194 | $31.23M | 1.0% | $18.91 | -50.4% | COM | 28036F105 |
| TNGX | TANGO THERAPEUTICS INC | 4,201,414 | $30.46M | 0.9% | $6.32 | +11.2% | COM | 87583X109 |
| AVIR | ATEA PHARMACEUTICALS INC | 6,184,861 | $29.75M | 0.9% | $14.25 | -64.5% | COM | 04683R106 |
| VYGR | VOYAGER THERAPEUTICS INC | 4,753,907 | $29M | 0.9% | $3.51 | — | COM | 92915B106 |
| ALLO | ALLOGENE THERAPEUTICS INC | 4,488,200 | $28.23M | 0.9% | $8.88 | +4.3% | COM | 019770106 |
| DYN | DYNE THERAPEUTICS INC | 2,322,384 | $26.92M | 0.8% | $11.57 | 0.0% | COM | 26818M108 |
| NUVB | NUVATION BIO INC | 13,896,543 | $26.68M | 0.8% | $11.16 | -81.9% | COM CL A | 67080N101 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 1,330,263 | $24.34M | 0.7% | $22.08 | -20.2% | COM | 22663K107 |
| ORIC | ORIC PHARMACEUTICALS INC | 3,418,068 | $20.13M | 0.6% | $30.24 | -88.8% | COM | 68622P109 |
| KYMR | KYMERA THERAPEUTICS INC | 796,093 | $19.87M | 0.6% | $26.36 | +1.2% | COM | 501575104 |
| — | GRAPHITE BIO INC | 5,712,096 | $18.96M | 0.6% | $4.50 | — | COM | 38870X104 |
| JANX | JANUX THERAPEUTICS INC | 1,421,319 | $18.72M | 0.6% | $22.27 | -34.3% | COM | 47103J105 |
| — | CHINOOK THERAPEUTICS INC | 690,000 | $18.08M | 0.6% | $16.36 | — | COM | 16961L106 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 5,232,279 | $16.22M | 0.5% | $4.60 | — | SPONSORED ADS | 152309100 |
| — | POSEIDA THERAPEUTICS INC | 2,650,000 | $14.04M | 0.4% | $3.53 | — | COM | 73730P108 |
| VTYX | VENTYX BIOSCIENCES INC | 400,000 | $13.12M | 0.4% | $18.95 | +56.3% | COM | 92332V107 |
| OVID | OVID THERAPEUTICS INC | 6,117,400 | $11.38M | 0.3% | $3.32 | -48.7% | COM | 690469101 |
| PRME | PRIME MEDICINE INC | 600,000 | $11.15M | 0.3% | $18.06 | 0.0% | COM ADDED | 74168J101 |
| CGEM | CULLINAN ONCOLOGY INC | 1,035,038 | $10.92M | 0.3% | $11.34 | +7.1% | COM | 230031106 |
| — | 2SEVENTY BIO INC | 1,143,494 | $10.71M | 0.3% | $21.76 | — | COMMON STOCK | 901384107 |
| GERN | GERON CORP | 4,028,507 | $9.749M | 0.3% | $1.60 | +40.3% | COM | 374163103 |
| — | AVEO PHARMACEUTICALS INC | 650,489 | $9.725M | 0.3% | $6.56 | — | COM NEW | 053588307 |
| BCAB | BIOATLA INC | 1,124,439 | $9.277M | 0.3% | $8.30 | 0.0% | COM | 09077B104 |
| DSGN | DESIGN THERAPEUTICS INC | 884,903 | $9.079M | 0.3% | $22.94 | -40.9% | COM | 25056L103 |
| — | GRACELL BIOTECHNOLOGIES INC | 3,343,202 | $7.689M | 0.2% | $2.66 | — | SPONSORED ADS | 38406L103 |
| MGNX | MACROGENICS INC | 1,117,455 | $7.498M | 0.2% | $4.10 | +33.7% | COM | 556099109 |
| IMTX | IMMATICS N.V | 743,000 | $6.472M | 0.2% | $10.34 | 0.0% | SHS | N44445109 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 415,322 | $6.147M | 0.2% | $16.92 | +3.3% | COM | 03969K108 |
| — | PRECISION BIOSCIENCES INC | 5,035,971 | $5.993M | 0.2% | $1.60 | — | COM | 74019P108 |
| — | HEALTH SCIENCES ACQ CORP 2 | 400,000 | $3.992M | 0.1% | $11.00 | — | ORD SHS | G4411D109 |
| — | SELECTA BIOSCIENCES INC | 3,500,000 | $3.955M | 0.1% | $1.31 | — | COM | 816212104 |
| — | PRAXIS PRECISION MEDICINES I | 1,585,324 | $3.773M | 0.1% | $2.30 | — | COM | 74006W108 |
| — | ALIGOS THERAPEUTICS INC | 3,948,360 | $3.762M | 0.1% | $2.37 | — | COM | 01626L105 |
| ABEO | ABEONA THERAPEUTICS INC | 1,086,956 | $3.348M | 0.1% | $3.74 | 0.0% | COM NEW | 00289Y206 |
| — | SURFACE ONCOLOGY INC | 3,924,713 | $3.218M | 0.1% | $2.94 | — | COM | 86877M209 |
| ERAS | ERASCA INC | 678,441 | $2.924M | 0.1% | $20.63 | -67.1% | COM | 29479A108 |
| — | HOOKIPA PHARMA INC | 2,473,489 | $2.004M | 0.1% | $2.28 | — | COM | 43906K100 |
| — | EUCRATES BIOMEDICAL ACQU COR | 200,000 | $1.998M | 0.1% | $9.98 | — | SHS | G3141W106 |
| — | NUVATION BIO INC | 963,333 | $1.85M | 0.1% | $10.45 | — | *W EXP 07/07/202 | 67080N119 |
| — | ARYA SCIENCES ACQU CORP IV | 150,000 | $1.515M | 0.0% | $10.47 | — | CL A | G31659108 |
| — | TEMPEST THERAPEUTICS INC | 1,031,268 | $1.186M | 0.0% | $2.15 | — | COM | 87978U108 |
| — | ITEOS THERAPEUTICS INC | 40,480 | $791K | 0.0% | $21.93 | — | COM | 46565G104 |
| NAMSW | NEWAMSTERDAM PHARMA COMPANY | 66,665 | $727K | 0.0% | $10.90 | — | *W EXP 11/22/202 ADDED | N62509117 |
| — | EUCRATES BIOMEDICAL ACQU COR | 66,666 | $666K | 0.0% | $9.90 | — | *W EXP 10/23/202 | G3141W122 |
| — | KRONOS BIO INC | 326,780 | $529K | 0.0% | $29.87 | — | COM | 50107A104 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 282,131 | $508K | 0.0% | $1.80 | 0.0% | COM | 09203E105 |
| — | CAREMAX INC | 100,000 | $365K | 0.0% | $12.90 | — | *W EXP 06/08/202 | 14171W111 |
| SRZNW | SURROZEN INC | 66,665 | $38,792 | 0.0% | $7.07 | — | *W EXP 08/01/203 | 86889P117 |