EcoR1 Capital, LLC Quant / Systematic

CIK: 0001587114 · Show all filings

Period: Q4 2022 (← Previous) (Next →)

Filing Date: Feb 14, 2023

Total Value ($000): $3,285,597 (100.0% shares, 0.0% debt)

Holdings (66)

PRTA PROTHENA CORP PLC 21.2%
Value ($000) $697,953 Shares 11,584,280 Est. Cost $11.63 Unrealized +403.3%
SRPT SAREPTA THERAPEUTICS INC 11.8%
Value ($000) $388,669 Shares 2,999,453 Est. Cost $76.84 Unrealized +50.8%
APLS APELLIS PHARMACEUTICALS INC 8.2%
Value ($000) $268,035 Shares 5,183,431 Est. Cost $40.43 Unrealized +31.2%
ANAB ANAPTYSBIO INC 7.1%
Value ($000) $233,077 Shares 7,521,024 Est. Cost $23.15 Unrealized +22.0%
GLPG GALAPAGOS NV 5.0%
Value ($000) $165,570 Shares 3,730,730 Est. Cost $54.33 Unrealized —
XNCR XENCOR INC 4.2%
Value ($000) $137,557 Shares 5,282,516 Est. Cost $33.50 Unrealized -16.5%
ARVN ARVINAS INC 3.3%
Value ($000) $106,848 Shares 3,123,300 Est. Cost $59.39 Unrealized -29.2%
RVMD REVOLUTION MEDICINES INC 3.2%
Value ($000) $106,207 Shares 4,458,731 Est. Cost $20.81 Unrealized +2.2%
— MORPHIC HLDG INC 3.2%
Value ($000) $105,704 Shares 3,951,566 Est. Cost $29.75 Unrealized —
ACAD ACADIA PHARMACEUTICALS INC 2.9%
Value ($000) $95,384 Shares 5,991,479 Est. Cost $22.11 Unrealized -29.3%
— SPRINGWORKS THERAPEUTICS INC 2.7%
Value ($000) $90,000 Shares 3,460,208 Est. Cost $28.53 Unrealized —
KURA KURA ONCOLOGY INC 2.5%
Value ($000) $82,382 Shares 6,638,371 Est. Cost $18.76 Unrealized -22.5%
ZLAB ZAI LAB LTD 2.0%
Value ($000) $66,241 Shares 2,157,686 Est. Cost $42.44 Unrealized —
RLAY RELAY THERAPEUTICS INC 1.9%
Value ($000) $62,208 Shares 4,163,824 Est. Cost $28.03 Unrealized -31.7%
ZYME ZYMEWORKS DEL INC 1.8%
Value ($000) $59,489 Shares 7,568,573 Est. Cost $7.03 Unrealized 0.0%
ALEC ALECTOR INC 1.1%
Value ($000) $37,442 Shares 4,056,548 Est. Cost $19.56 Unrealized -55.4%
— NGM BIOPHARMACEUTICALS INC 1.0%
Value ($000) $32,306 Shares 6,435,518 Est. Cost $5.88 Unrealized —
— ADICET BIO INC 1.0%
Value ($000) $31,833 Shares 3,560,700 Est. Cost $8.94 Unrealized —
EWTX EDGEWISE THERAPEUTICS INC 1.0%
Value ($000) $31,229 Shares 3,493,194 Est. Cost $18.91 Unrealized -50.4%
TNGX TANGO THERAPEUTICS INC 0.9%
Value ($000) $30,460 Shares 4,201,414 Est. Cost $6.32 Unrealized +11.2%
AVIR ATEA PHARMACEUTICALS INC 0.9%
Value ($000) $29,749 Shares 6,184,861 Est. Cost $14.25 Unrealized -64.5%
VYGR VOYAGER THERAPEUTICS INC 0.9%
Value ($000) $28,999 Shares 4,753,907 Est. Cost $3.51 Unrealized —
ALLO ALLOGENE THERAPEUTICS INC 0.9%
Value ($000) $28,231 Shares 4,488,200 Est. Cost $8.88 Unrealized +4.3%
DYN DYNE THERAPEUTICS INC 0.8%
Value ($000) $26,916 Shares 2,322,384 Est. Cost $11.57 Unrealized 0.0%
NUVB NUVATION BIO INC 0.8%
Value ($000) $26,681 Shares 13,896,543 Est. Cost $11.16 Unrealized -81.9%
CRNX CRINETICS PHARMACEUTICALS IN 0.7%
Value ($000) $24,344 Shares 1,330,263 Est. Cost $22.08 Unrealized -20.2%
ORIC ORIC PHARMACEUTICALS INC 0.6%
Value ($000) $20,132 Shares 3,418,068 Est. Cost $30.24 Unrealized -88.8%
KYMR KYMERA THERAPEUTICS INC 0.6%
Value ($000) $19,870 Shares 796,093 Est. Cost $26.36 Unrealized +1.2%
— GRAPHITE BIO INC 0.6%
Value ($000) $18,964 Shares 5,712,096 Est. Cost $4.50 Unrealized —
JANX JANUX THERAPEUTICS INC 0.6%
Value ($000) $18,719 Shares 1,421,319 Est. Cost $22.27 Unrealized -34.3%
— CHINOOK THERAPEUTICS INC 0.6%
Value ($000) $18,078 Shares 690,000 Est. Cost $16.36 Unrealized —
CNTA CENTESSA PHARMACEUTICALS PLC 0.5%
Value ($000) $16,220 Shares 5,232,279 Est. Cost $4.60 Unrealized —
— POSEIDA THERAPEUTICS INC 0.4%
Value ($000) $14,045 Shares 2,650,000 Est. Cost $3.53 Unrealized —
VTYX VENTYX BIOSCIENCES INC 0.4%
Value ($000) $13,116 Shares 400,000 Est. Cost $18.95 Unrealized +56.3%
OVID OVID THERAPEUTICS INC 0.3%
Value ($000) $11,378 Shares 6,117,400 Est. Cost $3.32 Unrealized -48.7%
PRME PRIME MEDICINE INC 0.3%
Value ($000) $11,148 Shares 600,000 Est. Cost $18.06 Unrealized 0.0%
CGEM CULLINAN ONCOLOGY INC 0.3%
Value ($000) $10,920 Shares 1,035,038 Est. Cost $11.34 Unrealized +7.1%
— 2SEVENTY BIO INC 0.3%
Value ($000) $10,715 Shares 1,143,494 Est. Cost $21.76 Unrealized —
GERN GERON CORP 0.3%
Value ($000) $9,749 Shares 4,028,507 Est. Cost $1.60 Unrealized +40.3%
— AVEO PHARMACEUTICALS INC 0.3%
Value ($000) $9,725 Shares 650,489 Est. Cost $6.56 Unrealized —
BCAB BIOATLA INC 0.3%
Value ($000) $9,277 Shares 1,124,439 Est. Cost $8.30 Unrealized 0.0%
DSGN DESIGN THERAPEUTICS INC 0.3%
Value ($000) $9,079 Shares 884,903 Est. Cost $22.94 Unrealized -40.9%
— GRACELL BIOTECHNOLOGIES INC 0.2%
Value ($000) $7,689 Shares 3,343,202 Est. Cost $2.66 Unrealized —
MGNX MACROGENICS INC 0.2%
Value ($000) $7,498 Shares 1,117,455 Est. Cost $4.10 Unrealized +33.7%
IMTX IMMATICS N.V 0.2%
Value ($000) $6,472 Shares 743,000 Est. Cost $10.34 Unrealized 0.0%
ARQT ARCUTIS BIOTHERAPEUTICS INC 0.2%
Value ($000) $6,147 Shares 415,322 Est. Cost $16.92 Unrealized +3.3%
— PRECISION BIOSCIENCES INC 0.2%
Value ($000) $5,993 Shares 5,035,971 Est. Cost $1.60 Unrealized —
— HEALTH SCIENCES ACQ CORP 2 0.1%
Value ($000) $3,992 Shares 400,000 Est. Cost $11.00 Unrealized —
— SELECTA BIOSCIENCES INC 0.1%
Value ($000) $3,955 Shares 3,500,000 Est. Cost $1.31 Unrealized —
— PRAXIS PRECISION MEDICINES I 0.1%
Value ($000) $3,773 Shares 1,585,324 Est. Cost $2.30 Unrealized —
— ALIGOS THERAPEUTICS INC 0.1%
Value ($000) $3,762 Shares 3,948,360 Est. Cost $2.37 Unrealized —
ABEO ABEONA THERAPEUTICS INC 0.1%
Value ($000) $3,348 Shares 1,086,956 Est. Cost $3.74 Unrealized 0.0%
— SURFACE ONCOLOGY INC 0.1%
Value ($000) $3,218 Shares 3,924,713 Est. Cost $2.94 Unrealized —
ERAS ERASCA INC 0.1%
Value ($000) $2,924 Shares 678,441 Est. Cost $20.63 Unrealized -67.1%
— HOOKIPA PHARMA INC 0.1%
Value ($000) $2,004 Shares 2,473,489 Est. Cost $2.28 Unrealized —
— EUCRATES BIOMEDICAL ACQU COR 0.1%
Value ($000) $1,998 Shares 200,000 Est. Cost $9.98 Unrealized —
— NUVATION BIO INC 0.1%
Value ($000) $1,850 Shares 963,333 Est. Cost $10.45 Unrealized —
— ARYA SCIENCES ACQU CORP IV 0.0%
Value ($000) $1,515 Shares 150,000 Est. Cost $10.47 Unrealized —
— TEMPEST THERAPEUTICS INC 0.0%
Value ($000) $1,186 Shares 1,031,268 Est. Cost $2.15 Unrealized —
— ITEOS THERAPEUTICS INC 0.0%
Value ($000) $791 Shares 40,480 Est. Cost $21.93 Unrealized —
NAMSW NEWAMSTERDAM PHARMA COMPANY 0.0%
Value ($000) $727 Shares 66,665 Est. Cost $10.90 Unrealized —
— EUCRATES BIOMEDICAL ACQU COR 0.0%
Value ($000) $666 Shares 66,666 Est. Cost $9.90 Unrealized —
— KRONOS BIO INC 0.0%
Value ($000) $529 Shares 326,780 Est. Cost $29.87 Unrealized —
BDTX BLACK DIAMOND THERAPEUTICS I 0.0%
Value ($000) $508 Shares 282,131 Est. Cost $1.80 Unrealized 0.0%
— CAREMAX INC 0.0%
Value ($000) $365 Shares 100,000 Est. Cost $12.90 Unrealized —
SRZNW SURROZEN INC 0.0%
Value ($000) $39 Shares 66,665 Est. Cost $7.07 Unrealized —