Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q2 2017 (← Previous) (Next →)
Filing Date: Aug 14, 2017
Total Value: $1.987B (99.6% shares, 0.4% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| FOLD | AMICUS THERAPEUTICS INC | 17,296,672 | $174M | 8.8% | $10.07 * | $3.99 | +101.7% | COM | 03152W109 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 3,577,589 | $165M | 8.3% | $46.00 * | $25.71 | +88.7% | COM | 64125C109 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 1,832,761 | $146M | 7.4% | $79.76 * | $52.98 | +20.6% | COM | 02043Q107 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 3,933,927 | $108M | 5.4% | $27.35 | $27.36 | — | COM | 37890U108 |
| — | VERSARTIS INC | 4,407,317 | $76.91M | 3.9% | $17.45 | $14.64 | — | COM | 92529L102 |
| — | LA JOLLA PHARMACEUTICAL CO | 2,157,011 | $64.21M | 3.2% | $29.77 | $22.99 | — | COM PAR $.0001 2 | 503459604 |
| PBYI | PUMA BIOTECHNOLOGY INC | 733,320 | $64.09M | 3.2% | $87.40 * | $55.94 | 0.0% | COM | 74587V107 |
| — | RETROPHIN INC | 2,672,309 | $51.82M | 2.6% | $19.39 | $14.79 | — | COM | 761299106 |
| — | TESARO INC | 359,551 | $50.29M | 2.5% | $139.86 | $72.96 | — | COM | 881569107 |
| — | ZOGENIX INC | 3,448,302 | $50M | 2.5% | $14.50 | $12.45 | — | COM NEW | 98978L204 |
| — | CORIUM INTL INC | 5,847,133 | $43.62M | 2.2% | $7.46 | $5.97 | — | COM | 21887L107 |
| — | NXSTAGE MEDICAL INC | 1,555,523 | $39M | 2.0% | $25.07 | $22.78 | — | COM | 67072V103 |
| — | DOVA PHARMACEUTICALS INC | 1,706,499 | $38.04M | 1.9% | $22.29 | $22.29 | — | COM | 25985T102 |
| SRPT | SAREPTA THERAPEUTICS | 1,089,961 | $36.74M | 1.8% | $33.71 * | $24.99 | +30.3% | COM | 803607100 |
| VRTX | VERTEX PHARMACEUTICALS INC | 277,352 | $35.74M | 1.8% | $128.87 * | $94.81 | +27.0% | COM | 92532F100 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 4,363,114 | $32.07M | 1.6% | $7.35 * | $6.36 | 0.0% | COM | 462260100 |
| — | RADIUS HEALTH INC | 645,873 | $29.21M | 1.5% | $45.23 | $43.12 | — | COM NEW | 750469207 |
| — | VBI VACCINES IN | 6,565,843 | $28.56M | 1.4% | $4.35 | $3.25 | — | COM NEW | 91822J103 |
| XNCR | XENCOR INC | 1,293,095 | $27.3M | 1.4% | $21.11 * | $11.62 | +92.9% | COM | 98401F105 |
| EVH | EVOLENT HEALTH INC | 1,074,327 | $27.23M | 1.4% | $25.35 * | $17.81 | +35.1% | CL A | 30050B101 |
| RGNX | REGENXBIO INC | 1,371,186 | $27.08M | 1.4% | $19.75 | $19.87 | -2.5% | COM | 75901B107 |
| — | QUOTIENT LTD | 3,714,486 | $26.01M | 1.3% | $7.00 | $9.26 | — | SHS | G73268107 |
| ANAB | ANAPTYSBIO INC | 952,269 | $22.79M | 1.1% | $23.93 * | $23.45 | +7.2% | COM | 032724106 |
| — | BLUEPRINT MEDICINES CORP | 444,661 | $22.53M | 1.1% | $50.67 | $31.50 | — | COM | 09627Y109 |
| — | AVEXIS INC | 271,181 | $22.28M | 1.1% | $82.16 | $45.07 | — | COM | 05366U100 |
| — | SAGE THERAPEUTICS INC | 275,000 | $21.9M | 1.1% | $79.64 | — | — | Call | 78667J108 |
| — | ACCELERON PHARMA INC | 711,259 | $21.61M | 1.1% | $30.39 | $28.52 | — | COM | 00434H108 |
| CTMX | CYTOMX THERAPEUTICS INC | 1,390,381 | $21.55M | 1.1% | $15.50 * | $12.53 | +20.3% | COM | 23284F105 |
| — | DBV TECHNOLOGIES S A | 591,765 | $21.13M | 1.1% | $35.71 | $34.37 | — | SPONSORED ADR | 23306J101 |
| — | KADMON HLDGS INC | 5,185,847 | $20.17M | 1.0% | $3.89 | $5.20 | — | COM | 48283N106 |
| ISRG | INTUITIVE SURGICAL INC | 20,695 | $19.36M | 1.0% | $935.35 * | $96.11 | 0.0% | COM NEW | 46120E602 |
| HUM | HUMANA INC | 78,093 | $18.79M | 0.9% | $240.62 * | $203.63 | +3.4% | COM | 444859102 |
| — | ALBIREO PHARMA INC | 845,000 | $17.41M | 0.9% | $20.60 | $20.60 | — | COM | 01345P106 |
| GLPG | GALAPAGOS NV | 226,405 | $17.32M | 0.9% | $76.52 | $67.75 | — | SPON ADR | 36315X101 |
| — | SELECTA BIOSCIENCES INC | 797,325 | $15.83M | 0.8% | $19.86 | $18.81 | — | COM | 816212104 |
| AKBA | AKEBIA THERAPEUTICS INC | 1,100,000 | $15.81M | 0.8% | $14.37 * | $12.48 | +1.5% | COM | 00972D105 |
| — | AVADEL PHARMACEUTICALS PLC | 1,429,114 | $15.76M | 0.8% | $11.03 | $10.39 | — | SPONSORED ADR | 05337M104 |
| — | MYOKARDIA INC | 553,154 | $14.49M | 0.7% | $26.20 | $15.01 | — | COM | 62857M105 |
| — | ANTARES PHARMA INC | 4,267,253 | $13.74M | 0.7% | $3.22 | $2.61 | — | COM | 036642106 |
| — | AUDENTES THERAPEUTICS INC | 707,500 | $13.53M | 0.7% | $19.13 | $19.12 | — | COM | 05070R104 |
| ALDX | ALDEYRA THERAPEUTICS INC | 2,885,458 | $13.42M | 0.7% | $4.65 | $6.73 | -31.7% | COM | 01438T106 |
| — | AVEO PHARMACEUTICALS INC | 6,010,660 | $13.34M | 0.7% | $2.22 | $1.03 | — | COM | 053588109 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 85,572 | $13.31M | 0.7% | $155.49 | $138.36 | +10.5% | SHS USD | G50871105 |
| — | AXOVANT SCIENCES LTD | 572,700 | $13.28M | 0.7% | $23.19 | $18.72 | — | COM | G0750W104 |
| WVE | WAVE LIFE SCIENCES LTD | 662,798 | $12.33M | 0.6% | $18.60 * | $17.06 | +26.3% | SHS | Y95308105 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 282,857 | $12.02M | 0.6% | $42.49 * | $27.34 | +33.2% | COM | 450056106 |
| — | ZYNERBA PHARMACEUTICALS INC | 100,000 | $10.16M | 0.5% | $101.64 | $12.65 | — | Put | 98986X109 |
| ARGX | ARGENX SE | 450,000 | $9.544M | 0.5% | $21.21 | $21.21 | — | SPONSORED ADR | 04016X101 |
| ARDX | ARDELYX INC | 1,810,581 | $9.233M | 0.5% | $5.10 * | $12.08 | -29.8% | COM | 039697107 |
| — | ASSEMBLY BIOSCIENCES INC | 441,833 | $9.124M | 0.5% | $20.65 | $7.21 | — | COM | 045396108 |
| — | RADIUS HEALTH INC | 200,000 | $9.046M | 0.5% | $45.23 | $43.12 | — | Put | 750469207 |
| — | CAPITAL SR LIVING CORP | 530,173 | $8.064M | 0.4% | $15.21 | $19.70 | — | COM | 140475104 |
| — | ACELRX PHARMACEUTICALS INC | 3,731,342 | $8.022M | 0.4% | $2.15 | $9.69 | — | COM | 00444T100 |
| — | ANI PHARMACEUTICALS INC | 7,500,000 | $7.908M | 0.4% | $1.05 | $1.05 | — | NOTE 3.000%12/0 | 00182CAA1 |
| EGRX | EAGLE PHARMACEUTICALS INC | 100,000 | $7.889M | 0.4% | $78.89 * | $81.78 | 0.0% | COM | 269796108 |
| — | CORBUS PHARMACEUTICALS HLDGS | 1,232,500 | $7.764M | 0.4% | $6.30 | $2.85 | — | COM | 21833P103 |
| — | AXOVANT SCIENCES LTD | 300,000 | $6.957M | 0.4% | $23.19 | $18.72 | — | Call | G0750W104 |
| QURE | UNIQURE NV | 1,090,119 | $6.748M | 0.3% | $6.19 * | $18.17 | -70.3% | SHS | N90064101 |
| — | VIVEVE MED INC | 890,468 | $6.394M | 0.3% | $7.18 | $6.33 | — | COM NEW | 92852W204 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 100,000 | $6.211M | 0.3% | $62.11 | — | — | Call | 90400D108 |
| — | INVITAE CORP | 649,500 | $6.209M | 0.3% | $9.56 | $8.36 | — | COM | 46185L103 |
| — | ZYMEWORKS INC | 730,768 | $6.101M | 0.3% | $8.35 | $8.35 | — | COM | 98985W102 |
| ANIP | ANI PHARMACEUTICALS INC | 125,399 | $5.869M | 0.3% | $46.80 * | $60.02 | -19.6% | COM | 00182C103 |
| — | CLEARSIDE BIOMEDICAL INC | 620,181 | $5.649M | 0.3% | $9.11 | $7.22 | — | COM | 185063104 |
| UNH | UNITEDHEALTH GROUP INC | 28,480 | $5.281M | 0.3% | $185.43 * | $143.13 | +6.7% | COM | 91324P102 |
| — | FOAMIX PHARMACEUTICALS LTD | 1,117,324 | $5.184M | 0.3% | $4.64 | $7.58 | — | SHS | M46135105 |
| URGN | UROGEN PHARMA LTD | 269,014 | $4.858M | 0.2% | $18.06 * | $17.36 | 0.0% | COM | M96088105 |
| — | ABEONA THERAPEUTICS INC | 1,259,636 | $4.285M | 0.2% | $3.40 | $3.40 | — | *W EXP 12/24/201 | 00289Y115 |
| — | SIERRA ONCOLOGY INC | 3,655,186 | $4.277M | 0.2% | $1.17 | $1.53 | — | COM | 82640U107 |
| — | FORWARD PHARMA A/S | 194,718 | $3.959M | 0.2% | $20.33 | $18.28 | — | SPONSORED ADR | 34986J105 |
| — | NEPTUNE TECHNOLOGIES BIORESO | 6,519,634 | $3.801M | 0.2% | $0.58 | $3.13 | — | COM | 64077P108 |
| EXAS | EXACT SCIENCES CORP | 100,000 | $3.537M | 0.2% | $35.37 * | $19.82 | +55.8% | COM | 30063P105 |
| — | PFENEX INC | 845,973 | $3.392M | 0.2% | $4.01 | $13.00 | — | COM | 717071104 |
| — | HISTOGENICS CORP | 1,777,777 | $3.182M | 0.2% | $1.79 | $3.21 | — | COM | 43358V109 |
| — | BIOHAVEN PHARMACTL HLDG CO L | 120,000 | $3M | 0.2% | $25.00 | $25.00 | — | COM | G11196105 |
| ADMA | ADMA BIOLOGICS INC | 721,102 | $2.769M | 0.1% | $3.84 * | $6.35 | -36.7% | COM | 000899104 |
| — | ABEONA THERAPEUTICS INC | 422,873 | $2.706M | 0.1% | $6.40 | $4.32 | — | COM | 00289Y107 |
| — | OCERA THERAPEUTICS INC | 2,038,880 | $2.365M | 0.1% | $1.16 | $1.31 | — | COM | 67552A108 |
| — | VERONA PHARMA PLC | 200,000 | $2.331M | 0.1% | $11.65 | $11.65 | — | SPONSORED ADS | 925050106 |
| XENE | XENON PHARMACEUTICALS INC | 723,853 | $2.28M | 0.1% | $3.15 * | $9.34 | -58.2% | COM | 98420N105 |
| — | MGC DIAGNOSTICS CORP | 252,327 | $2.14M | 0.1% | $8.48 | $8.55 | — | COM | 552768103 |
| — | BLUEBIRD BIO INC | 20,000 | $2.101M | 0.1% | $105.05 | $101.76 | — | COM | 09609G100 |
| — | ADAMIS PHARMACEUTICALS CORP | 400,000 | $2.08M | 0.1% | $5.20 | $5.20 | — | COM NEW | 00547W208 |
| — | PSIVIDA CORP | 1,149,556 | $1.966M | 0.1% | $1.71 | $2.93 | — | COM | 74440J101 |
| — | CURIS INC | 951,201 | $1.798M | 0.1% | $1.89 | $2.36 | — | COM | 231269101 |
| — | BRAINSTORM CELL THERAPEUTICS | 400,000 | $1.66M | 0.1% | $4.15 | $4.15 | — | COM NEW | 10501E201 |
| — | ALLIQUA BIOMEDICAL INC | 4,233,951 | $1.566M | 0.1% | $0.37 | $0.64 | — | COM NEW | 019621200 |
| — | CARA THERAPEUTICS INC | 100,000 | $1.539M | 0.1% | $15.39 | — | — | Call | 140755109 |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 847,458 | $1.372M | 0.1% | $1.62 | $1.98 | -18.4% | COM | 04280A100 |
| — | AFFIMED N V | 668,214 | $1.369M | 0.1% | $2.05 | $2.48 | — | COM | N01045108 |
| — | EIGER BIOPHARMACEUTICALS INC | 157,679 | $1.245M | 0.1% | $7.90 | $15.33 | — | COM | 28249U105 |
| EXEL | EXELIXIS SHARES | 46,361 | $1.142M | 0.1% | $24.63 * | $14.43 | +46.7% | COM | 30161Q104 |
| LNTH | LANTHEUS HLDGS INC | 53,763 | $949K | 0.0% | $17.65 * | $6.62 | +122.2% | COM | 516544103 |
| OSUR | ORASURE TECHNOLOGIES INC | 54,729 | $945K | 0.0% | $17.27 * | $10.91 | +32.0% | COM | 68554V108 |
| CSBR | CHAMPIONS ONCOLOGY INC | 366,973 | $943K | 0.0% | $2.57 | $6.08 | -57.1% | COM NEW | 15870P307 |
| — | AZURRX BIOPHARMA INC | 227,272 | $916K | 0.0% | $4.03 | $4.74 | — | COM | 05502L105 |
| — | WELLCARE HEALTH PLANS INC | 5,056 | $908K | 0.0% | $179.59 | $94.74 | — | COM | 94946T106 |
| — | ONCOBIOLOGICS INC | 837,886 | $837K | 0.0% | $1.00 | $3.40 | — | COM | 68235M105 |
| — | HESKA CORP | 7,300 | $745K | 0.0% | $102.05 | $104.53 | — | COM RESTRC NEW | 42805E306 |
| — | OXFORD IMMUNOTEC GLOBAL PLC | 44,106 | $741K | 0.0% | $16.80 | $16.80 | — | ORD SHS | G6855A103 |
| — | LHC GROUP INC | 10,730 | $728K | 0.0% | $67.85 | $54.15 | — | COM | 50187A107 |
| EW | EDWARDS LIFESCIENCES CORP | 6,088 | $719K | 0.0% | $118.10 * | $36.50 | 0.0% | COM | 28176E108 |
| INCY | INCYTE CORP | 5,619 | $707K | 0.0% | $125.82 | $84.26 | +51.0% | COM | 45337C102 |
| — | ZOSANO PHARMA CORP | 500,000 | $705K | 0.0% | $1.41 | $1.90 | — | COM | 98979H103 |
| — | FIAT CHRYSLER AUTOMOBILES N | 62,000 | $659K | 0.0% | $10.63 | $14.53 | — | SHS | N31738102 |
| — | HILL ROM HLDGS INC | 7,930 | $631K | 0.0% | $79.57 | $62.01 | — | COM | 431475102 |
| — | ACORDA THERAPEUTICS INC | 31,786 | $626K | 0.0% | $19.69 | $19.69 | — | COM | 00484M106 |
| CNC | CENTENE CORP DEL | 7,726 | $617K | 0.0% | $79.86 * | $33.47 | +12.8% | COM | 15135B101 |
| — | ACHAOGEN INC | 27,551 | $599K | 0.0% | $21.74 | $24.72 | — | COM | 004449104 |
| VNDA | VANDA PHARMACEUTICALS INC | 36,232 | $591K | 0.0% | $16.31 * | $14.25 | +1.1% | COM | 921659108 |
| MOH | MOLINA HEALTHCARE INC | 8,140 | $563K | 0.0% | $69.16 * | $61.36 | 0.0% | COM | 60855R100 |
| RACE | FERRARI N V | 6,200 | $533K | 0.0% | $85.97 * | $40.37 | +102.9% | COM | N3167Y103 |
| — | PROTEON THERAPEUTICS INC | 334,116 | $518K | 0.0% | $1.55 | $8.74 | — | COM | 74371L109 |
| ICLR | ICON PLC | 5,187 | $507K | 0.0% | $97.74 * | $88.44 | 0.0% | SHS | G4705A100 |
| — | INC RESH HLDGS INC | 8,532 | $499K | 0.0% | $58.49 | $58.49 | — | CL A | 45329R109 |
| — | CIDARA THERAPEUTICS INC | 62,110 | $465K | 0.0% | $7.49 | $12.72 | — | COM | 171757107 |
| — | DIPLOMAT PHARMACY INC | 30,658 | $454K | 0.0% | $14.81 | $14.81 | — | COM | 25456K101 |
| — | PORTOLA PHARMACEUTICALS INC | 7,870 | $442K | 0.0% | $56.16 | $39.19 | — | COM | 737010108 |
| VYGR | VOYAGER THERAPEUTICS INC | 34,604 | $310K | 0.0% | $8.96 | $8.96 | — | COM | 92915B106 |
| — | CUTERA INC | 11,981 | $310K | 0.0% | $25.87 | $20.68 | — | COM | 232109108 |
| — | PERNIX THERAPEUTICS HLDGS IN | 1,000,000 | $282K | 0.0% | $0.28 | $0.20 | — | DBCV 4.250% 4/0 | 71426VAK4 |
| — | ACASTI PHARMA INC | 186,559 | $247K | 0.0% | $1.32 | $2.51 | — | COM | 00430K402 |
| ARNI | ARNO THERAPEUTICS INC | 4,177,577 | $208K | 0.0% | $0.05 | $0.59 | -93.9% | COM | 042564203 |
| — | ONCOBIOLOGICS INC | 462,500 | $80,000 | 0.0% | $0.17 | $0.46 | — | W EXP 02/18/201 | 68235M113 |
| — | ONCOBIOLOGICS INC | 462,500 | $42,000 | 0.0% | $0.09 | $0.66 | — | *W EXP 05/18/201 | 68235M121 |
| — | PEREGRINE PHARMACEUTICALS IN | 24,332 | $15,000 | 0.0% | $0.62 | $0.37 | — | COM NEW | 713661304 |