Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q3 2019 (← Previous) (Next →)
Filing Date: Nov 14, 2019
Total Value: $3.712B (99.8% shares, 0.2% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| NBIX | NEUROCRINE BIOSCIENCES INC | 4,059,900 | $366M | 9.9% | $90.11 * | $39.11 | +138.9% | COM | 64125C109 |
| — | GLOBAL BLOOD THERAPEUTICS INC | 5,875,726 | $285M | 7.7% | $48.52 | $32.23 | — | COM | 37890U108 |
| — | MIRATI THERAPEUTICS INC | 3,314,606 | $258M | 7.0% | $77.91 | $88.23 | — | COM | 60468T105 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 11,014,702 | $200M | 5.4% | $18.20 * | $9.56 | +131.4% | COM | 462260100 |
| FOLD | AMICUS THERAPEUTICS INC | 24,609,700 | $197M | 5.3% | $8.02 * | $6.62 | +63.9% | COM | 03152W109 |
| BBIO | BRIDGEBIO PHARMA INC | 6,706,268 | $144M | 3.9% | $21.47 * | $27.26 | +1.5% | COM | 10806X102 |
| — | ZOGENIX INC | 3,264,152 | $131M | 3.5% | $40.04 | $16.63 | — | COM | 98978L204 |
| — | ATHENEX INC | 10,735,245 | $131M | 3.5% | $12.16 | $14.95 | — | COM | 04685N103 |
| — | AMARIN CORPORATION PLC | 7,636,079 | $116M | 3.1% | $15.16 | $15.39 | — | SPONS ADR NEW | 023111206 |
| — | DOVA PHARMACEUTICALS INC | 3,708,705 | $104M | 2.8% | $27.95 | $23.68 | — | COM | 25985T102 |
| MGTX | MEIRAGTX HOLDINGS PLC | 6,433,277 | $103M | 2.8% | $15.95 * | $14.20 | +63.9% | COM | G59665102 |
| — | QUOTIENT LTD | 10,789,054 | $83.83M | 2.3% | $7.77 | $7.33 | — | SHS | G73268107 |
| — | NEVRO CORP | 974,773 | $83.8M | 2.3% | $85.97 | $63.98 | — | COM | 64157F103 |
| — | SOLID BIOSCIENCES INC | 6,749,803 | $69.79M | 1.9% | $10.34 | $7.67 | — | COM | 83422E105 |
| — | SPRINGWORKS THERAPEUTICS INC | 3,217,522 | $69.75M | 1.9% | $21.68 | $21.68 | — | COM | 85205L107 |
| — | BLUEPRINT MEDICINES CORP | 883,264 | $64.89M | 1.7% | $73.47 | $65.89 | — | COM | 09627Y109 |
| — | ZYMEWORKS INC | 2,388,890 | $59.24M | 1.6% | $24.80 | $19.22 | — | COM | 98985W102 |
| — | MYOKARDIA INC | 1,130,511 | $58.96M | 1.6% | $52.15 | $33.39 | — | COM | 62857M105 |
| ADMA | ADMA BIOLOGICS INC | 11,521,102 | $51.27M | 1.4% | $4.45 * | $4.23 | -1.3% | COM | 000899104 |
| — | VERRICA PHARMACEUTICALS INC | 3,410,412 | $50.34M | 1.4% | $14.76 | $19.73 | — | COM | 92511W108 |
| — | NEPTUNE WELLNESS SOLUTIONS INC | 13,436,906 | $47.84M | 1.3% | $3.56 | $3.77 | — | COM | 64079L105 |
| — | VBI VACCINES INC | 45,951,556 | $45.95M | 1.2% | $1.00 | $1.73 | — | COM | 91822J103 |
| KOD | KODIAK SCIENCES INC | 3,135,199 | $45.08M | 1.2% | $14.38 * | $8.85 | +47.5% | COM | 50015M109 |
| — | ARENA PHARMACEUTICALS INC | 953,129 | $43.62M | 1.2% | $45.77 | $43.70 | — | COM NEW | 040047607 |
| ALLO | ALLOGENE THERAPEUTICS INC | 1,543,790 | $42.08M | 1.1% | $27.25 * | $26.57 | +7.2% | COM | 019770106 |
| CRNX | CRINETICS PHARMACEUTICALS INC | 2,587,953 | $38.92M | 1.0% | $15.04 * | $29.69 | -34.5% | COM | 22663K107 |
| — | RETROPHIN INC | 3,270,571 | $37.91M | 1.0% | $11.59 | $16.80 | — | COM | 761299106 |
| — | MOMENTA PHARMACEUTICALS INC | 2,905,000 | $37.65M | 1.0% | $12.96 | $11.17 | — | COM | 60877T100 |
| — | ALBIREO PHARMA INC | 1,704,330 | $34.09M | 0.9% | $20.00 | $24.69 | — | COM | 01345P106 |
| — | FOAMIX PHARMACEUTICALS LTD | 11,203,881 | $34.06M | 0.9% | $3.04 | $4.02 | — | COM | M46135105 |
| — | SPARK THERAPEUTICS INC | 350,000 | $33.94M | 0.9% | $96.98 | $102.38 | — | COM | 84652J103 |
| — | KADMON HOLDINGS INC | 13,165,746 | $33.18M | 0.9% | $2.52 | $4.47 | — | COM | 48283N106 |
| — | DBV TECHNOLOGIES SA | 3,609,084 | $31.04M | 0.8% | $8.60 | $12.08 | — | SPONSORED ADR | 23306J101 |
| — | PROTAGONIST THERAPEUTICS INC | 2,071,297 | $24.88M | 0.7% | $12.01 | $10.55 | — | COM | 4366E1029 |
| — | EIDOS THERAPEUTICS INC | 686,992 | $24.71M | 0.7% | $35.97 | $20.34 | — | COM | 28249H104 |
| CTMX | CYTOMX THERAPEUTICS INC | 3,253,923 | $24.01M | 0.6% | $7.38 * | $17.25 | -42.8% | COM | 23284F105 |
| ESTA | ESTABLISHMENT LABS HOLDINGS INC | 1,260,528 | $23.84M | 0.6% | $18.91 * | $24.75 | -13.1% | COM | G31249108 |
| — | INVITAE CORP | 1,198,182 | $23.09M | 0.6% | $19.27 | $10.95 | — | COM | 46185L103 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,977,412 | $23.04M | 0.6% | $11.65 * | $17.16 | -27.7% | COM | 77313F106 |
| — | TURNING POINT THERAPEUTICS I | 597,190 | $22.45M | 0.6% | $37.60 | $39.81 | — | COM | 90041T108 |
| — | Y-MABS THERAPEUTICS INC | 854,940 | $22.28M | 0.6% | $26.06 | $26.06 | — | COM | 984241109 |
| RGNX | REGENXBIO INC | 608,000 | $21.64M | 0.6% | $35.60 * | $38.79 | +4.4% | COM | 75901B107 |
| BIO | BIO-RAD LABORATORIES INC SHS-A- | 65,000 | $21.63M | 0.6% | $332.74 | $326.21 | 0.0% | COM | 090572207 |
| UROV | UROVANT SCIENCES LTD | 2,246,547 | $21.27M | 0.6% | $9.47 | $9.12 | — | COM | G9381B108 |
| EHTH | EHEALTH INC | 255,089 | $17.04M | 0.5% | $66.79 * | $54.08 | +66.8% | COM | 28238P109 |
| — | VAPOTHERM INC | 1,764,470 | $16.71M | 0.5% | $9.47 | $18.08 | — | COM | 922107107 |
| ALDX | ALDEYRA THERAPEUTICS INC | 3,085,458 | $16.26M | 0.4% | $5.27 * | $6.64 | -18.9% | COM | 01438T106 |
| MMSI | MERIT MEDICAL SYSTEMS INC | 528,788 | $16.11M | 0.4% | $30.46 * | $43.97 | -8.0% | COM | 589889104 |
| STOK | STOKE THERAPEUTICS DEAL SHARES | 671,978 | $14.44M | 0.4% | $21.49 * | $26.85 | +3.8% | COM | 86150R107 |
| — | MOLECULAR TEMPLATES INC | 1,974,133 | $13.01M | 0.4% | $6.59 | $5.56 | — | COM | 608550109 |
| — | CONCERT PHARMACEUTICALS INC | 2,194,641 | $12.9M | 0.3% | $5.88 | $12.16 | — | COM | 206022105 |
| — | AGILE THERAPEUTICS INC | 10,726,750 | $12.71M | 0.3% | $1.18 | $1.44 | — | COM | 00847L100 |
| — | MORPHIC HOLDING INC | 650,000 | $11.77M | 0.3% | $18.11 | $19.82 | — | COM | 61775R105 |
| TXG | 10X GENOMICS INC | 220,000 | $11.09M | 0.3% | $50.40 * | $55.34 | 0.0% | CL A COM | 88025U109 |
| SCPE/U | SC HEALTH CORP | 1,000,000 | $10.35M | 0.3% | $10.35 | $10.35 | — | UNIT 99/99/9999 | G78516302 |
| — | MARKER THERAPEUTICS INC | 2,000,000 | $10.22M | 0.3% | $5.11 | $5.55 | — | COM | 57055L107 |
| IDYA | IDEAYA BIOSCIENCES INC | 1,141,484 | $9.584M | 0.3% | $8.40 * | $10.88 | -29.8% | COM | 45166A102 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 295,000 | $9.116M | 0.2% | $30.90 * | $44.18 | -7.6% | COM | 00650F109 |
| — | MOTUS GI HLDGS INC | 4,210,542 | $8.336M | 0.2% | $1.98 | $4.01 | — | COM | 62014P108 |
| — | CYMABAY THERAPEUTICS INC | 1,520,355 | $7.784M | 0.2% | $5.12 | $10.41 | — | COM | 23257D103 |
| — | TELADOC HEALTH INC | 5,000,000 | $7.398M | 0.2% | $1.48 | $1.48 | — | NOTE 1.375% 5/1 | 87918AAC9 |
| — | MEI PHARMA INC | 4,400,440 | $7.392M | 0.2% | $1.68 | $2.64 | — | COM NEW | 55279B202 |
| ALEC | ALECTOR INC | 511,731 | $7.379M | 0.2% | $14.42 * | $18.92 | -4.6% | COM | 014442107 |
| VRAYQ | VIEWRAY INC | 2,451,748 | $7.11M | 0.2% | $2.90 * | $9.17 | -35.4% | COM | 92672L107 |
| ZBH | ZIMMER BIOMET HLDGS INC | 50,000 | $6.864M | 0.2% | $137.28 * | $122.61 | 0.0% | COM | 98956P102 |
| — | AQUESTIVE THERAPEUTICS INC | 2,113,400 | $6.72M | 0.2% | $3.18 | $6.30 | — | COM | 3843E1047 |
| HCAT | HEALTH CATALYST INC | 210,924 | $6.674M | 0.2% | $31.64 * | $39.36 | 0.0% | COM | 42225T107 |
| — | INTERCEPT PHARMACEUTICALS INC | 97,600 | $6.477M | 0.2% | $66.36 | $79.57 | — | COM | 45845P108 |
| — | ORCHARD THERAPETICS PLC | 521,800 | $6.198M | 0.2% | $11.88 | $15.73 | — | ADS | 68570P101 |
| — | SELECT INTERIOR CONCEPTS INC | 440,000 | $5.707M | 0.2% | $12.97 | $12.97 | — | CL A | 816120307 |
| — | PROVENTION BIO INC | 666,322 | $4.548M | 0.1% | $6.83 | $6.83 | — | COM | 74374N102 |
| — | CERNER CORP | 65,000 | $4.431M | 0.1% | $68.17 | $68.17 | — | COM | 156782104 |
| — | TRANSLATE BIO INC | 435,000 | $4.311M | 0.1% | $9.91 | $12.65 | — | COM | 89374L104 |
| — | HEALTH SCIENCES ACQUISITIONS CORP | 400,000 | $4.292M | 0.1% | $10.73 | $10.60 | — | UNIT 04/01/2024 | 42227C201 |
| ATEC | ALPHATEC HOLDINGS INC | 850,000 | $4.267M | 0.1% | $5.02 * | $5.20 | 0.0% | COM NEW | 02081G201 |
| FULC | FULCRUM THERAPEUTICS INC | 600,000 | $3.984M | 0.1% | $6.64 * | $11.06 | 0.0% | COM | 359616109 |
| — | VERU INC | 1,650,000 | $3.564M | 0.1% | $2.16 | $1.52 | — | COM | 92536C103 |
| TWST | TWIST BIOSCIENCE CORP | 145,856 | $3.483M | 0.1% | $23.88 * | $27.08 | +7.3% | COM | 90184D100 |
| — | ACASTI PHARMA INC | 1,779,882 | $3.364M | 0.1% | $1.89 | $0.83 | — | CL A NEW | 00430K402 |
| ONC | BEIGENE LTD | 400,000 | $2.698M | 0.1% | $6.75 | — | — | Put | 07725L102 |
| — | VOCERA COMMUNICATIONS INC | 99,804 | $2.46M | 0.1% | $24.65 | $31.85 | — | COM | 92857F107 |
| — | CORREVIO PHARMA CORP | 1,000,000 | $2M | 0.1% | $2.00 | $2.00 | — | COM | 22026V105 |
| XBI | SPDR SERIES TRUST | 900,000 | $1.604M | 0.0% | $1.78 | — | — | Put | 78464A870 |
| — | SEATTLE GENETICS INC | 17,000 | $1.452M | 0.0% | $85.41 | $85.41 | — | COM | 812578102 |
| — | EIGER BIOPHARMACEUTICALS INC | 139,890 | $1.433M | 0.0% | $10.24 | $15.33 | — | COM | 28249U105 |
| AORT | CRYOLIFE INC | 50,000 | $1.358M | 0.0% | $27.16 * | $28.53 | -0.8% | COM | 228903100 |
| AXSM | AXSOME THERAPEUTICS INC | 53,879 | $1.091M | 0.0% | $20.25 * | $9.29 | +176.7% | COM | 05464T104 |
| — | SIERRA ONCOLOGY INC | 2,666,190 | $1.041M | 0.0% | $0.39 | $2.12 | — | COM | 82640U107 |
| — | MEDICINES CO | 19,532 | $977K | 0.0% | $50.02 | $36.45 | — | COM | 584688105 |
| RACE | FERRARI N.V. | 6,200 | $955K | 0.0% | $154.03 * | $40.37 | +295.3% | COM | N3167Y103 |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | 30,738 | $866K | 0.0% | $28.17 * | $7.12 | +315.7% | COM | 04280A100 |
| — | FIAT CHRYSLER AUTOMOBILES N | 62,000 | $802K | 0.0% | $12.94 | $14.84 | — | SHS | N31739102 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 200,000 | $750K | 0.0% | $3.75 | — | — | Put | 09061G101 |
| NVCR | NOVOCURE LTD | 9,489 | $710K | 0.0% | $74.82 * | $79.97 | 0.0% | ORD SHS | G6674U108 |
| — | ZYNERBA PHARMACEUTICALS INC | 200,000 | $635K | 0.0% | $3.17 | — | — | Put | 98986X109 |
| MREO | MEREO BIOPHARMA GROUP PLC | 179,419 | $534K | 0.0% | $2.98 | $2.52 | — | ADS | 589492107 |
| MEDP | MEDPACE HLDGS INC | 6,328 | $532K | 0.0% | $84.07 * | $75.56 | 0.0% | COM | 58506Q109 |
| — | KARYOPHARM THERAPEUTICS INC | 54,645 | $526K | 0.0% | $9.63 | $9.63 | — | COM | 48576U106 |
| — | ALLENA PHARMACEUTICALS INC | 132,300 | $521K | 0.0% | $3.94 | $10.06 | — | COM | 018119107 |
| — | ALLAKOS INC | 6,444 | $507K | 0.0% | $78.68 | $78.68 | — | COM | 01671P100 |
| NTRA | NATERA INC | 14,549 | $477K | 0.0% | $32.79 * | $22.06 | +34.0% | COM | 632307104 |
| — | ARQULE INC | 54,500 | $391K | 0.0% | $7.17 | $7.17 | — | COM | 4269E1073 |
| TNDM | TANDEM DIABETES CARE INC | 6,422 | $379K | 0.0% | $59.02 * | $35.31 | +80.8% | COM | 875372203 |
| — | G1 THERAPEUTICS INC | 15,702 | $358K | 0.0% | $22.80 | $22.80 | — | COM | 3621LQ109 |
| — | RA PHARMACEUTICALS INC | 14,455 | $342K | 0.0% | $23.66 | $23.66 | — | COM | 74933V108 |
| — | MIRATI THERAPEUTICS INC | 100,000 | $145K | 0.0% | $1.45 | $88.23 | — | Put | 60468T105 |
| — | ABEONA THERAPEUTICS INC | 659,636 | $145K | 0.0% | $0.22 | $3.40 | — | W EXP 12/24/201 | 00289Y115 |
| — | CONFORMIS INC | 50,000 | $93,000 | 0.0% | $1.86 | $1.86 | — | COM | 20717E101 |
| — | OUTLOOK THERAPEUTICS INC | 420,875 | $48,000 | 0.0% | $0.11 | $0.17 | — | *W EXP 02/18/202 | 69012T115 |