Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q2 2019 (← Previous) (Next →)
Filing Date: Aug 14, 2019
Total Value: $4.358B (99.8% shares, 0.2% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| NBIX | NEUROCRINE BIOSCIENCES INC | 4,023,862 | $340M | 7.8% | $84.43 * | $39.11 | +110.0% | COM | 64125C109 |
| — | GLOBAL BLOOD THERAPEUTICS INC | 5,775,726 | $304M | 7.0% | $52.60 | $31.95 | — | COM | 37890U108 |
| — | MIRATI THERAPEUTICS INC | 2,899,606 | $299M | 6.9% | $103.00 | $89.70 | — | COM | 60468T105 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 11,915,127 | $292M | 6.7% | $24.52 * | $9.56 | +57.6% | COM | 462260100 |
| FOLD | AMICUS THERAPEUTICS INC | 21,509,486 | $268M | 6.2% | $12.48 | $6.01 | +111.1% | COM | 03152W109 |
| — | ATHENEX INC | 9,822,118 | $188M | 4.3% | $19.10 | $15.21 | — | COM | 04685N103 |
| BBIO | BRIDGEBIO PHARMA INC | 6,706,268 | $181M | 4.2% | $26.97 | $27.26 | 0.0% | COM | 10806X102 |
| — | ZOGENIX INC | 3,507,223 | $168M | 3.8% | $47.78 | $16.63 | — | COM | 98978L204 |
| MGTX | MEIRAGTX HOLDINGS PLC | 6,007,746 | $156M | 3.6% | $25.93 * | $13.56 | +52.3% | COM | G59665102 |
| — | AMARIN CORPORATION PLC | 6,201,269 | $120M | 2.8% | $19.39 | $15.44 | — | SPONS ADR NEW | 023111206 |
| — | BLUEPRINT MEDICINES CORP | 1,212,731 | $114M | 2.6% | $94.33 | $65.89 | — | COM | 09627Y109 |
| — | QUOTIENT LTD | 10,789,054 | $101M | 2.3% | $9.35 | $7.33 | — | SHS | G73268107 |
| — | ARENA PHARMACEUTICALS INC | 1,380,171 | $80.92M | 1.9% | $58.63 | $43.70 | — | COM NEW | 040047607 |
| — | RETROPHIN INC | 3,772,582 | $75.79M | 1.7% | $20.09 | $16.80 | — | COM | 761299106 |
| — | NEVRO CORP | 1,137,765 | $73.76M | 1.7% | $64.83 | $63.98 | — | COM | 64157F103 |
| CRNX | CRINETICS PHARMACEUTICALS INC | 2,587,953 | $64.7M | 1.5% | $25.00 | $29.69 | -16.6% | COM | 22663K107 |
| — | MYOKARDIA INC | 1,100,511 | $55.18M | 1.3% | $50.14 | $32.88 | — | COM | 62857M105 |
| — | ALBIREO PHARMA INC | 1,704,330 | $54.95M | 1.3% | $32.24 | $24.69 | — | COM | 01345P106 |
| ASND | ASCENDIS PHARMA A S | 473,475 | $54.52M | 1.3% | $115.15 | $68.34 | — | SPONSORED ADR | 04351P101 |
| — | ZYMEWORKS INC | 2,368,890 | $52.12M | 1.2% | $22.00 | $19.22 | — | COM | 98985W102 |
| — | DOVA PHARMACEUTICALS INC | 3,553,060 | $50.1M | 1.1% | $14.10 | $23.49 | — | COM | 25985T102 |
| RGNX | REGENXBIO INC | 970,997 | $49.88M | 1.1% | $51.37 * | $38.79 | +28.7% | COM | 75901B107 |
| MMSI | MERIT MEDICAL SYSTEMS INC | 817,209 | $48.67M | 1.1% | $59.56 * | $43.97 | +30.4% | COM | 589889104 |
| — | ARRAY BIOPHARMA INC | 1,038,390 | $48.11M | 1.1% | $46.33 | $24.38 | — | COM | 04269X105 |
| VRAYQ | VIEWRAY INC | 5,455,243 | $48.06M | 1.1% | $8.81 * | $9.17 | -11.4% | COM | 92672L107 |
| ADMA | ADMA BIOLOGICS INC | 11,521,102 | $44.59M | 1.0% | $3.87 * | $4.23 | +4.3% | COM | 000899104 |
| ALLO | ALLOGENE THERAPEUTICS INC | 1,543,790 | $41.45M | 1.0% | $26.85 * | $26.57 | +4.9% | COM | 019770106 |
| — | VERRICA PHARMACEUTICALS INC | 3,410,412 | $39.63M | 0.9% | $11.62 | $19.73 | — | COM | 92511W108 |
| KOD | KODIAK SCIENCES INC | 3,135,199 | $36.68M | 0.8% | $11.70 * | $8.85 | +0.5% | COM | 50015M109 |
| — | MOMENTA PHARMACEUTICALS INC | 2,905,000 | $36.17M | 0.8% | $12.45 | $11.17 | — | COM | 60877T100 |
| — | SPARK THERAPEUTICS INC | 350,000 | $35.83M | 0.8% | $102.38 | $102.38 | — | COM | 84652J103 |
| CTMX | CYTOMX THERAPEUTICS INC | 3,153,923 | $35.39M | 0.8% | $11.22 * | $17.48 | -40.0% | COM | 23284F105 |
| EHTH | EHEALTH INC | 385,982 | $33.23M | 0.8% | $86.10 * | $54.08 | +24.4% | COM | 28238P109 |
| — | VAPOTHERM INC | 1,404,470 | $32.3M | 0.7% | $23.00 | $20.29 | — | COM | 922107107 |
| — | INVITAE CORP | 1,343,491 | $31.57M | 0.7% | $23.50 | $10.95 | — | COM | 46185L103 |
| — | NEPTUNE WELLNESS SOLUTIONS INC | 8,891,452 | $29.98M | 0.7% | $3.37 | $3.88 | — | COM | 64079L105 |
| — | DBV TECHNOLOGIES S A | 3,609,084 | $29.67M | 0.7% | $8.22 | $12.08 | — | SPONSORED ADR | 23306J101 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,977,412 | $29.66M | 0.7% | $15.00 * | $17.16 | +1.7% | COM | 77313F106 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 1,260,528 | $27.72M | 0.6% | $21.99 * | $24.75 | -3.5% | COM | G31249108 |
| — | CYMABAY THERAPEUTICS INC | 3,862,821 | $27.66M | 0.6% | $7.16 | $10.41 | — | COM | 23257D103 |
| — | KADMON HOLDINGS INC | 13,165,746 | $27.12M | 0.6% | $2.06 | $4.47 | — | COM | 48283N106 |
| — | CONCERT PHARMACEUTICALS INC | 2,204,641 | $26.46M | 0.6% | $12.00 | $12.16 | — | COM | 206022105 |
| — | PROTAGONIST THERAPEUTICS INC | 2,071,297 | $25.08M | 0.6% | $12.11 | $10.55 | — | COM | 4366E1029 |
| — | VBI VACCINES INC | 25,951,556 | $24.61M | 0.6% | $0.95 | $2.29 | — | COM | 91822J103 |
| — | SOLID BIOSCIENCES INC | 3,927,222 | $22.58M | 0.5% | $5.75 | $5.75 | — | COM | 83422E105 |
| QURE | UNIQURE N.V | 281,820 | $22.02M | 0.5% | $78.15 * | $28.36 | +124.7% | COM | N90064101 |
| — | EIDOS THERAPEUTICS INC | 686,992 | $21.35M | 0.5% | $31.08 | $20.34 | — | COM | 28249H104 |
| TDOC | TELADOC HEALTH INC | 307,021 | $20.39M | 0.5% | $66.41 * | $61.07 | -4.6% | COM | 87918A105 |
| STOK | STOKE THERAPEUTICS INC | 671,978 | $19.6M | 0.4% | $29.17 * | $26.85 | 0.0% | COM | 86150R107 |
| ALDX | ALDEYRA THERAPEUTICS INC | 3,085,458 | $18.51M | 0.4% | $6.00 * | $6.64 | +13.4% | COM | 01438T106 |
| — | TURNING POINT THERAPEUTICS I | 424,968 | $17.3M | 0.4% | $40.70 | $40.70 | — | COM | 90041T108 |
| — | MOLECULAR TEMPLATES INC | 1,974,133 | $16.48M | 0.4% | $8.35 | $5.56 | — | COM | 608550109 |
| — | MARKER THERAPEUTICS INC | 2,000,000 | $15.84M | 0.4% | $7.92 | $5.55 | — | COM | 57055L107 |
| BHC | BAUSCH HEALTH COS INC | 600,000 | $15.13M | 0.3% | $25.22 * | $23.88 | -0.6% | COM | 071734107 |
| UROV | UROVANT SCIENCES LTD | 1,875,426 | $14.84M | 0.3% | $7.91 | $9.05 | — | COM | G9381B108 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 285,000 | $13.77M | 0.3% | $48.30 * | $44.30 | 0.0% | COM | 00650F109 |
| — | MORPHIC HOLDING INC | 650,000 | $12.88M | 0.3% | $19.82 | $19.82 | — | COM | 61775R105 |
| — | MOTUS GI HLDGS INC | 4,210,542 | $12.76M | 0.3% | $3.03 | $4.01 | — | COM | 62014P108 |
| — | AXONICS MODULATION TECHNOLOGIES INC | 285,502 | $11.7M | 0.3% | $40.97 | $14.56 | — | COM | 05465P101 |
| IDYA | IDEAYA BIOSCIENCES INC | 1,141,484 | $11.37M | 0.3% | $9.96 * | $10.88 | 0.0% | COM | 45166A102 |
| — | FOAMIX PHARMACEUTICALS LTD | 4,661,824 | $11.1M | 0.3% | $2.38 | $5.40 | — | SHS | M46135105 |
| — | MEI PHARMA INC | 4,400,440 | $11M | 0.3% | $2.50 | $2.64 | — | COM NEW | 55279B202 |
| — | AGILE THERAPEUTICS INC | 8,426,750 | $10.44M | 0.2% | $1.24 | $1.51 | — | COM | 00847L100 |
| — | FIAT CHRYSLER AUTOMOBILES N | 62,000 | $10.01M | 0.2% | $161.42 | $14.84 | — | SHS | N31739102 |
| ALEC | ALECTOR INC | 511,731 | $9.325M | 0.2% | $18.22 * | $18.92 | +7.3% | COM | 014442107 |
| — | ANI PHARMACEUTICALS INC | 7,500,000 | $8.992M | 0.2% | $1.20 | $1.05 | — | NOTE 3.000% 12/0 | 00182CAA1 |
| DXCM | DEXCOM INC | 60,000 | $8.99M | 0.2% | $149.83 * | $31.43 | 0.0% | COM | 252131107 |
| — | AQUESTIVE THERAPEUTICS INC | 2,113,400 | $8.876M | 0.2% | $4.20 | $6.30 | — | COM | 3843E1047 |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | 330,738 | $8.765M | 0.2% | $26.50 * | $7.12 | +208.3% | COM | 04280A100 |
| — | ACORDA THERAPEUTICS INC | 1,127,318 | $8.647M | 0.2% | $7.67 | $7.67 | — | COM | 00484M106 |
| — | SHOCKWAVE MEDICAL INC | 150,000 | $8.564M | 0.2% | $57.09 | $33.47 | — | COM | 82489T104 |
| — | SERES THERAPEUTICS INC | 2,500,000 | $8.05M | 0.2% | $3.22 | $3.22 | — | COM | 81750R102 |
| — | SYNLOGIC INC | 867,852 | $7.897M | 0.2% | $9.10 | $16.39 | — | COM | 87166L100 |
| — | INTERCEPT PHARMACEUTICALS INC | 97,600 | $7.766M | 0.2% | $79.57 | $79.57 | — | COM | 45845P108 |
| — | ORCHARD THERAPEUTICS PLC | 521,800 | $7.299M | 0.2% | $13.99 | $15.73 | — | ADS | 68570P101 |
| THC | TENET HEALTHCARE CORP | 300,633 | $6.211M | 0.1% | $20.66 * | $23.05 | 0.0% | COM | 88033G407 |
| — | VOCERA COMMUNICATIONS INC | 194,400 | $6.205M | 0.1% | $31.92 | $31.85 | — | COM | 92857F107 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 262,970 | $5.785M | 0.1% | $22.00 * | $26.65 | -5.2% | COM | 76243J105 |
| — | TRANSLATE BIO INC | 435,000 | $5.494M | 0.1% | $12.63 | $12.65 | — | COM | 89374L104 |
| — | ROCKWELL MEDICAL INC | 1,500,000 | $4.515M | 0.1% | $3.01 | $3.01 | — | COM | 774374102 |
| — | HEALTH SCIENCES ACQUISITIONS CORP | 400,000 | $4.241M | 0.1% | $10.60 | $10.60 | — | UNIT 04/01/2024 | 42227C201 |
| TWST | TWIST BIOSCIENCE CORP | 110,856 | $3.216M | 0.1% | $29.01 * | $26.45 | 0.0% | COM | 90184D100 |
| — | VERU INC | 1,445,000 | $3.078M | 0.1% | $2.13 | $1.43 | — | COM | 92536C103 |
| — | ACASTI PHARMA INC | 1,779,882 | $2.029M | 0.0% | $1.14 | $0.83 | — | CL A NEW | 00430K402 |
| AORT | CRYOLIFE INC | 50,000 | $1.497M | 0.0% | $29.94 | $28.53 | +4.0% | COM | 228903100 |
| — | SIERRA ONCOLOGY INC | 2,666,190 | $1.493M | 0.0% | $0.56 | $2.12 | — | COM | 82640U107 |
| — | EIGER BIOPHARMACEUTICALS INC | 139,890 | $1.482M | 0.0% | $10.59 | $15.33 | — | COM | 28249U105 |
| AXSM | AXSOME THERAPEUTICS INC | 53,879 | $1.387M | 0.0% | $25.74 * | $9.29 | +115.9% | COM | 05464T104 |
| RACE | FERRARI N.V. | 6,200 | $1.001M | 0.0% | $161.45 * | $40.37 | +256.6% | COM | N3167Y103 |
| VYGR | VOYAGER THERAPEUTICS INC | 36,573 | $996K | 0.0% | $27.23 | $27.23 | — | COM | 92915B106 |
| — | MEDICINES CO | 19,532 | $712K | 0.0% | $36.45 | $36.45 | — | COM | 584688105 |
| — | ABEONA THERAPEUTICS INC | 659,636 | $620K | 0.0% | $0.94 | $3.40 | — | *W EXP 12/24/201 | 00289Y115 |
| GH | GUARDANT HEALTH INC | 6,617 | $571K | 0.0% | $86.29 * | $76.37 | 0.0% | COM | 40131M109 |
| LAB | FLUIDIGM CORP | 46,030 | $567K | 0.0% | $12.32 * | $10.54 | +20.8% | COM | 34385P108 |
| — | ALLENA PHARMACEUTICALS INC | 132,300 | $538K | 0.0% | $4.07 | $10.06 | — | COM | 018119107 |
| — | ZIOPHARM ONCOLOGY INC | 90,498 | $528K | 0.0% | $5.83 | $5.83 | — | COM | 98973P101 |
| MREO | MEREO BIOPHARMA GROUP PLC | 179,419 | $452K | 0.0% | $2.52 | $2.52 | — | ADS | 589492107 |
| — | CONFORMIS INC | 100,000 | $436K | 0.0% | $4.36 | $4.36 | — | COM | 0717E1010 |
| TNDM | TANDEM DIABETES CARE INC | 6,422 | $414K | 0.0% | $64.47 | $35.31 | +82.8% | COM | 875372203 |
| NTRA | NATERA INC | 14,549 | $401K | 0.0% | $27.56 * | $22.06 | 0.0% | COM | 632307104 |
| XBI | SPDR SERIES TRUST | 200,000 | $70,000 | 0.0% | $0.35 | — | — | Put | 78464A870 |
| BIIB | BIOGEN INC | 200,000 | $65,000 | 0.0% | $0.33 | — | — | Call | 09062X103 |
| — | OUTLOOK THERAPEUTICS INC | 420,875 | $46,000 | 0.0% | $0.11 | $0.17 | — | *W EXP 02/18/202 | 69012T115 |
| — | SOLID BIOSCIENCES INC | 200 | $23,000 | 0.0% | $115.00 | $5.75 | — | Call | 83422E105 |