Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q2 2021 (← Previous) (Next →)
Filing Date: Aug 17, 2021
Total Value: $7.706B
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | MIRATI THERAPEUTICS INC | 3,185,898 | $515M | 6.7% | $161.53 | $111.11 | — | COM | 60468T105 |
| BBIO | BRIDGEBIO PHARMA INC | 7,756,928 | $473M | 6.1% | $60.96 * | $32.43 | +76.1% | COM | 10806X102 |
| — | SPRINGWORKS THERAPEUTICS INC | 4,849,912 | $400M | 5.2% | $82.41 | $36.75 | — | COM | 85205L107 |
| — | RETROPHIN INC | 45,000,000 | $384M | 5.0% | $8.54 | $0.78 | — | NOTE 2.500% 9/1 | 761299AB2 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 10,959,772 | $285M | 3.7% | $26.02 | $15.79 | +64.6% | COM | 462260100 |
| FOLD | AMICUS THERAPEUTICS INC | 23,121,329 | $223M | 2.9% | $9.64 | $6.71 | +45.5% | COM | 03152W109 |
| — | COLLEGIUM PHARMACEUTICAL INC | 17,500,000 | $190M | 2.5% | $10.84 | $8.98 | — | NOTE 2.625% 2/1 | 19459JAA2 |
| — | HORIZON THERAPEUTICS PUB L | 1,985,002 | $186M | 2.4% | $93.64 | $73.15 | — | SHS | G46188101 |
| — | VBI VACCINES INC CDA | 55,042,465 | $184M | 2.4% | $3.35 | $1.95 | — | COM NEW | 91822J103 |
| — | LANDOS BIOPHARMA INC | 14,869,915 | $172M | 2.2% | $11.55 | $9.48 | — | COM | 515069102 |
| — | INVITAE CORP | 4,818,801 | $163M | 2.1% | $33.73 | $41.81 | — | COM | 46185L103 |
| — | NEVRO CORP | 9,000,000 | $156M | 2.0% | $17.36 | $13.50 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| — | ZYMEWORKS INC | 4,305,600 | $149M | 1.9% | $34.69 | $28.60 | — | COM | 98985W102 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 4,152,689 | $145M | 1.9% | $35.02 | $32.86 | — | COM | 37890U108 |
| — | NEVRO CORP | 818,760 | $136M | 1.8% | $165.79 | $89.62 | — | COM | 64157F103 |
| RCKT | ROCKET PHARMACEUTICALS INC | 2,751,603 | $122M | 1.6% | $44.29 | $23.99 | +81.0% | COM | 77313F106 |
| — | OUTSET MED INC | 2,387,535 | $119M | 1.5% | $49.98 | $50.00 | — | COM | 690145107 |
| — | CEREVEL THERAPEUTICS HLDNG I | 4,643,095 | $119M | 1.5% | $25.62 | $16.52 | — | COM | 15678U128 |
| ALDX | ALDEYRA THERAPEUTICS INC | 9,903,879 | $112M | 1.5% | $11.33 * | $8.42 | +42.8% | COM | 01438T106 |
| UTHR | UNITED THERAPEUTICS CORP DEL | 616,802 | $111M | 1.4% | $179.41 * | $183.72 | +3.7% | COM | 91307C102 |
| MGTX | MEIRAGTX HLDGS PLC | 6,948,277 | $108M | 1.4% | $15.50 * | $14.20 | +0.7% | COM | G59665102 |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | 8,911,151 | $90M | 1.2% | $10.10 * | $10.83 | 0.0% | COM | 63909J108 |
| CCCC | C4 THERAPEUTICS INC | 2,258,566 | $85.46M | 1.1% | $37.84 * | $29.00 | +23.5% | COM STK | 12529R107 |
| — | SINGULAR GENOMICS SYSTEMS IN | 3,082,870 | $84.72M | 1.1% | $27.48 | $27.48 | — | COM | 82933R100 |
| — | ALBIREO PHARMA INC | 2,360,139 | $83.03M | 1.1% | $35.18 | $25.25 | — | COM | 01345P106 |
| — | PROMETHEUS BIOSCIENCES INC | 3,314,032 | $81.39M | 1.1% | $24.56 | $16.70 | — | COM | 74349U108 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 811,832 | $79.01M | 1.0% | $97.32 | $49.72 | +92.8% | COM | 64125C109 |
| — | RAPT THERAPEUTICS INC | 2,475,660 | $78.7M | 1.0% | $31.79 | $20.64 | — | COM | 75382E109 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 3,963,517 | $74.71M | 1.0% | $18.85 * | $25.34 | -30.7% | COM | 22663K107 |
| RLAY | RELAY THERAPEUTICS INC | 2,018,097 | $73.84M | 1.0% | $36.59 * | $38.13 | -13.6% | COM | 75943R102 |
| BEAM | BEAM THERAPEUTICS INC | 537,635 | $69.2M | 0.9% | $128.71 * | $95.13 | -16.2% | COM | 07373V105 |
| — | ZYMERGEN INC | 1,633,332 | $65.35M | 0.8% | $40.01 | $40.01 | — | COM | 98985X100 |
| CHRS | COHERUS BIOSCIENCES INC | 4,697,612 | $64.97M | 0.8% | $13.83 * | $18.23 | -22.3% | COM | 19249H103 |
| — | ATHENEX INC | 13,532,467 | $62.52M | 0.8% | $4.62 | $14.52 | — | COM | 04685N103 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 700,408 | $61.17M | 0.8% | $87.34 * | $34.47 | +115.8% | COM | G31249108 |
| — | KADMON HLDGS INC | 15,711,334 | $60.8M | 0.8% | $3.87 | $4.45 | — | COM | 48283N106 |
| — | KRONOS BIO INC | 2,528,052 | $60.55M | 0.8% | $23.95 | $29.87 | — | COM | 50107A104 |
| — | QUOTIENT LTD | 16,200,818 | $58.97M | 0.8% | $3.64 | $7.28 | — | SHS | G73268107 |
| MGNX | MACROGENICS INC | 2,148,060 | $57.7M | 0.7% | $26.86 * | $20.23 | +44.8% | COM | 556099109 |
| MDT | MEDTRONIC PLC | 450,000 | $55.86M | 0.7% | $124.13 * | $109.50 | 0.0% | SHS | G5960L103 |
| — | MORPHIC HLDG INC | 938,140 | $53.84M | 0.7% | $57.39 | $40.72 | — | COM | 61775R105 |
| — | SOLID BIOSCIENCES INC | 13,412,552 | $49.09M | 0.6% | $3.66 | $4.84 | — | COM | 83422E105 |
| AVIR | ATEA PHARMACEUTICALS INC | 2,259,224 | $48.53M | 0.6% | $21.48 * | $32.23 | -6.8% | COM | 04683R106 |
| — | COHERUS BIOSCIENCES INC | 4,500,000 | $46.05M | 0.6% | $10.23 | $10.23 | — | NOTE 1.500% 4/1 | 19249HAB9 |
| — | CAREMAX INC | 3,320,000 | $42.83M | 0.6% | $12.90 | $12.90 | — | COM CL A | 14171W103 |
| — | DBV TECHNOLOGIES S A | 7,695,505 | $42.02M | 0.5% | $5.46 | $8.17 | — | SPONSORED ADR | 23306J101 |
| APLS | APELLIS PHARMACEUTICALS INC | 661,162 | $41.78M | 0.5% | $63.20 * | $51.60 | 0.0% | COM | 03753U106 |
| — | VERRICA PHARMACEUTICALS INC | 3,610,412 | $40.8M | 0.5% | $11.30 | $19.48 | — | COM | 92511W108 |
| — | RAIN THERAPEUTICS INC | 2,537,019 | $39.42M | 0.5% | $15.54 | $15.54 | — | COM | 75082Q105 |
| TMCI | TREACE MED CONCEPTS INC | 1,235,886 | $38.63M | 0.5% | $31.26 | $31.83 | 0.0% | COM | 89455T109 |
| TARS | TARSUS PHARMACEUTICALS INC | 1,296,416 | $37.57M | 0.5% | $28.98 * | $28.48 | +9.6% | COM | 87650L103 |
| AXSM | AXSOME THERAPEUTICS INC | 553,908 | $37.37M | 0.5% | $67.46 * | $60.01 | 0.0% | COM | 05464T104 |
| — | VERU INC | 4,451,342 | $35.92M | 0.5% | $8.07 | $6.58 | — | COM | 92536C103 |
| — | ATHIRA PHARMA INC | 3,425,916 | $35.08M | 0.5% | $10.24 | $18.45 | — | COM | 04746L104 |
| HCAT | HEALTH CATALYST INC | 566,084 | $31.42M | 0.4% | $55.51 * | $43.17 | +23.4% | COM | 42225T107 |
| XENE | XENON PHARMACEUTICALS INC | 1,678,973 | $31.26M | 0.4% | $18.62 | $17.98 | +2.5% | COM | 98420N105 |
| — | DICERNA PHARMACEUTICALS INC | 800,000 | $29.86M | 0.4% | $37.32 | $25.40 | — | COM | 253031108 |
| BCAB | BIOATLA INC | 685,519 | $29.05M | 0.4% | $42.38 * | $45.18 | 0.0% | COM | 09077B104 |
| EXAS | EXACT SCIENCES CORP | 233,523 | $29.03M | 0.4% | $124.31 * | $136.88 | -12.8% | COM | 30063P105 |
| IMTX | IMMATICS N.V | 2,500,000 | $29.02M | 0.4% | $11.61 | $10.53 | +11.5% | SHS | N44445109 |
| — | INARI MED INC | 310,437 | $28.96M | 0.4% | $93.28 | $52.14 | — | COM | 45332Y109 |
| — | IVERIC BIO INC | 4,585,512 | $28.93M | 0.4% | $6.31 | $6.13 | — | COM | 46583P102 |
| — | ACCELERON PHARMA INC | 226,760 | $28.46M | 0.4% | $125.49 | $125.49 | — | COM | 00434H108 |
| NUVB | NUVATION BIO INC | 3,041,004 | $28.31M | 0.4% | $9.31 * | $11.18 | +2.0% | COM CL A | 67080N101 |
| ATEC | ALPHATEC HLDGS INC | 1,800,180 | $27.58M | 0.4% | $15.32 | $15.74 | -2.0% | COM NEW | 02081G201 |
| TVTX | TRAVERE THERAPEUTICS INC | 1,845,555 | $26.93M | 0.3% | $14.59 * | $23.35 | -15.5% | COM | 89422G107 |
| — | GRAPHITE BIO INC | 875,093 | $26.89M | 0.3% | $30.73 | $30.73 | — | COM | 38870X104 |
| RNAM | AVIDITY BIOSCIENCES INC | 1,079,028 | $26.66M | 0.3% | $24.71 * | $28.83 | -19.3% | COM | 05370A108 |
| KOD | KODIAK SCIENCES INC | 286,041 | $26.6M | 0.3% | $93.00 * | $12.82 | +648.5% | COM | 50015M109 |
| ADMA | ADMA BIOLOGICS INC | 16,584,802 | $26.54M | 0.3% | $1.60 * | $4.00 | -56.0% | COM | 000899104 |
| RGEN | REPLIGEN CORP | 132,500 | $26.45M | 0.3% | $199.62 * | $193.99 | 0.0% | COM | 759916109 |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 315,141 | $26.1M | 0.3% | $82.82 * | $63.95 | +16.4% | COM | 04280A100 |
| — | LYRA THERAPEUTICS INC | 3,222,560 | $25.88M | 0.3% | $8.03 | $11.34 | — | COM | 55234L105 |
| COGT | COGENT BIOSCIENCES INC | 3,188,750 | $25.86M | 0.3% | $8.11 * | $10.99 | -23.1% | COM | 19240Q201 |
| PMVP | PMV PHARMACEUTICALS INC | 746,557 | $25.5M | 0.3% | $34.16 * | $37.57 | -11.1% | COM | 69353Y103 |
| — | INHIBRX INC | 907,090 | $24.96M | 0.3% | $27.52 | $27.52 | — | COM | 45720L107 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 742,699 | $24.84M | 0.3% | $33.44 * | $27.45 | 0.0% | COM NEW | 15117B202 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 978,277 | $23.13M | 0.3% | $23.64 * | $19.57 | +18.1% | COM | 19459J104 |
| — | FORTE BIOSCIENCES INC | 685,000 | $23.03M | 0.3% | $33.62 | $35.36 | — | COM | 34962G109 |
| STOK | STOKE THERAPEUTICS INC | 671,978 | $22.62M | 0.3% | $33.66 * | $26.85 | +31.6% | COM | 86150R107 |
| — | AGILE THERAPEUTICS INC | 15,919,925 | $21.17M | 0.3% | $1.33 | $1.63 | — | COM | 00847L100 |
| — | VYNE THERAPEUTICS INC | 5,773,954 | $20.27M | 0.3% | $3.51 | $6.85 | — | COM | 92941V209 |
| — | ONCORUS INC | 1,463,599 | $20.2M | 0.3% | $13.80 | $32.33 | — | COM | 68236R103 |
| CLOV | CLOVER HEALTH INVESTMENTS CO | 1,500,000 | $19.98M | 0.3% | $13.32 * | $11.28 | -13.0% | COM CL A | 18914F103 |
| — | VERONA PHARMA PLC | 2,888,889 | $18.89M | 0.2% | $6.54 | $6.24 | — | SPONSORED ADS | 925050106 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 756,047 | $17.21M | 0.2% | $22.77 * | $20.76 | 0.0% | COM | 23954D109 |
| — | 1LIFE HEALTHCARE INC | 516,044 | $17.06M | 0.2% | $33.06 | $32.21 | — | COM | 68269G107 |
| — | CM LIFE SCIENCES II INC | 1,250,000 | $16.81M | 0.2% | $13.45 | $12.80 | — | UNIT 02/25/2028 | 125842203 |
| TDOC | TELADOC HEALTH INC | 100,000 | $16.63M | 0.2% | $166.29 | — | — | CALL | 87918A105 |
| — | CATABASIS PHARMACEUTICALS IN | 7,687,185 | $16.22M | 0.2% | $2.11 | $2.31 | — | COM NEW | 14875P206 |
| — | NANOSTRING TECHNOLOGIES INC | 1,000,000 | $16.19M | 0.2% | $16.19 | $16.19 | — | NOTE 2.625% 3/0 | 63009RAD1 |
| IMCR | IMMUNOCORE HLDGS PLC | 400,000 | $15.62M | 0.2% | $39.05 | $42.57 | — | ADS | 45258D105 |
| — | THERAPEUTICS ACQUISITION COR | 1,500,000 | $15.4M | 0.2% | $10.27 | $14.38 | — | COM CL A | 88339T103 |
| — | NEPTUNE WELLNESS SOLUTIONS I | 12,849,706 | $15.03M | 0.2% | $1.17 | $3.20 | — | COM | 64079L105 |
| ACRS | ACLARIS THERAPEUTICS INC | 850,000 | $14.93M | 0.2% | $17.56 * | $20.30 | +11.9% | COM | 00461U105 |
| HYPR | HEALTHCOR CATALIO ACQU CORP | 1,500,000 | $14.78M | 0.2% | $9.85 | $9.92 | — | CL A SHRS | G44125105 |
| NBTX | NANOBIOTIX SA | 1,059,800 | $14.6M | 0.2% | $13.78 | $16.50 | — | SPONSORED ADS | 63009J107 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 794,506 | $14.53M | 0.2% | $18.29 * | $17.12 | 0.0% | COM | 92790C104 |
| ADPT | ADAPTIVE BIOTECHNOLOGIES COR | 352,804 | $14.42M | 0.2% | $40.86 * | $40.48 | -4.0% | COM | 00650F109 |
| VTRS | VIATRIS INC | 1,004,419 | $14.35M | 0.2% | $14.29 * | $13.33 | -11.0% | COM | 92556V106 |
| — | FUSION PHARMACEUTICALS INC | 1,775,167 | $14.34M | 0.2% | $8.08 | $16.08 | — | COM | 36118A100 |
| — | LEAP THERAPEUTICS INC | 8,476,496 | $13.9M | 0.2% | $1.64 | $1.68 | — | COM | 52187K101 |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | 491,332 | $13.87M | 0.2% | $28.23 * | $34.43 | -12.9% | COM | 413197104 |
| — | CM LIFE SCIENCES III INC | 1,250,000 | $13.69M | 0.2% | $10.95 | $10.95 | — | UNIT 04/30/2028 | 125841205 |
| — | ACCOLADE INC | 245,741 | $13.35M | 0.2% | $54.31 | $41.33 | — | COM | 00437E102 |
| CVRX | CVRX INC | 440,000 | $12.32M | 0.2% | $28.00 | $28.00 | 0.0% | COM | 126638105 |
| — | BCLS ACQUISITION CORP | 1,000,000 | $10.53M | 0.1% | $10.53 | $11.14 | — | COM CL A | G0904B105 |
| CTMX | CYTOMX THERAPEUTICS INC | 1,640,957 | $10.39M | 0.1% | $6.33 * | $17.25 | -54.9% | COM | 23284F105 |
| — | RESEARCH ALLIANCE CORP II | 1,000,000 | $10.14M | 0.1% | $10.14 | $10.25 | — | COM CL A | 760873109 |
| — | SUMMIT HEALTHCRE ACQUISTN CO | 1,000,000 | $10.01M | 0.1% | $10.01 | $10.01 | — | UNIT 06/03/2026 | G8566R128 |
| — | CODEX DNA INC | 425,000 | $9.35M | 0.1% | $22.00 | $22.00 | — | COM | 192003101 |
| — | CONCERT PHARMACEUTICALS INC | 2,150,641 | $9.075M | 0.1% | $4.22 | $12.16 | — | COM | 206022105 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 375,256 | $9.036M | 0.1% | $24.08 * | $41.28 | -25.8% | COM | 35104E100 |
| — | PROVENTION BIO INC | 948,481 | $7.996M | 0.1% | $8.43 | $13.33 | — | COM | 74374N102 |
| — | POSEIDA THERAPEUTICS INC | 787,745 | $7.893M | 0.1% | $10.02 | $8.87 | — | COM | 73730P108 |
| — | ACHILLES THERAPEUTICS PLC | 755,375 | $7.395M | 0.1% | $9.79 | $16.55 | — | SPONSORED ADS | 00449L102 |
| — | SILK RD MED INC | 147,133 | $7.042M | 0.1% | $47.86 | $44.75 | — | COM | 82710M100 |
| — | DARIOHEALTH CORP | 327,869 | $7.003M | 0.1% | $21.36 | $19.26 | — | COM NEW | 23725P209 |
| TSHA | TAYSHA GENE THERAPIES INC | 320,440 | $6.793M | 0.1% | $21.20 * | $23.52 | -2.0% | COM SHS | 877619106 |
| PRVA | PRIVIA HEALTH GROUP INC | 135,000 | $5.99M | 0.1% | $44.37 * | $36.59 | 0.0% | COM | 74276R102 |
| — | AKOYA BIOSCIENCES INC | 300,000 | $5.802M | 0.1% | $19.34 | $19.34 | — | COM | 00974H104 |
| — | BCTG ACQUISITION CORP | 500,000 | $5.69M | 0.1% | $11.38 | $10.36 | — | COM | 05492W103 |
| MREO | MEREO BIOPHARMA GROUP PLC | 1,696,068 | $5.377M | 0.1% | $3.17 | $3.37 | — | ADS | 589492107 |
| — | CONSONANCE HFW ACQUISITION C | 500,000 | $5.2M | 0.1% | $10.40 | $10.47 | — | UNIT 99/99/9999 | G2445M129 |
| PRTA | PROTHENA CORP PLC | 100,000 | $5.141M | 0.1% | $51.41 * | $31.20 | 0.0% | SHS | G72800108 |
| — | LONGVIEW ACQUISITION CORP II | 500,000 | $5.04M | 0.1% | $10.08 | $10.04 | — | UNIT 99/99/9999 | 54319Q204 |
| — | HEALTH SCIENCES ACQ CORP 2 | 450,000 | $4.59M | 0.1% | $10.20 | $11.00 | — | ORD SHS | G4411D109 |
| TARA | PROTARA THERAPEUTICS INC | 421,641 | $4.107M | 0.1% | $9.74 * | $23.19 | -51.2% | COM STK | 74365U107 |
| — | MERUS NV | 175,000 | $3.687M | 0.0% | $21.07 | $20.89 | — | COM | N5749R100 |
| — | AMERICAN WELL CORP | 290,000 | $3.648M | 0.0% | $12.58 | $29.06 | — | CL A | 03044L105 |
| RGNX | REGENXBIO INC | 89,283 | $3.469M | 0.0% | $38.85 * | $41.11 | -13.0% | COM | 75901B107 |
| — | CM LIFE SCIENCES INC | 227,000 | $3.18M | 0.0% | $14.01 | $14.50 | — | COM CL A | 18978W109 |
| FULC | FULCRUM THERAPEUTICS INC | 294,118 | $3.082M | 0.0% | $10.48 * | $10.11 | 0.0% | COM | 359616109 |
| — | LIFESCI ACQUISITION II CORP | 300,000 | $3M | 0.0% | $10.00 | $10.67 | — | COM | 53229E103 |
| GRTX | GALERA THERAPEUTICS INC | 254,664 | $2.503M | 0.0% | $9.83 * | $12.19 | -33.4% | COM | 36338D108 |
| — | FREQUENCY THERAPEUTICS INC | 222,222 | $2.213M | 0.0% | $9.96 | $16.61 | — | COM | 35803L108 |
| — | CEREVEL THERAPEUTICS HLDNG I | 133,066 | $1.914M | 0.0% | $14.38 | $4.31 | — | *W EXP 06/09/202 | 15678U102 |
| — | MOTUS GI HLDGS INC | 1,800,542 | $1.873M | 0.0% | $1.04 | $4.01 | — | COM | 62014P108 |
| — | SIGILON THERAPEUTICS INC | 125,000 | $1.341M | 0.0% | $10.73 | $48.03 | — | COM | 82657L107 |
| — | SIERRA ONCOLOGY INC | 66,655 | $1.298M | 0.0% | $19.47 | $9.96 | — | COM NEW | 82640U404 |
| RACE | FERRARI N V | 6,200 | $1.278M | 0.0% | $206.13 | $40.37 | +416.6% | COM | N3167Y103 |
| — | EIGER BIOPHARMACEUTICALS INC | 139,890 | $1.192M | 0.0% | $8.52 | $15.33 | — | COM | 28249U105 |
| BFLYW | BUTTERFLY NETWORK INC | 233,333 | $1.127M | 0.0% | $4.83 | $6.45 | — | *W EXP 02/12/202 | 124155110 |
| — | SC HEALTH CORP | 500,000 | $1.055M | 0.0% | $2.11 | $1.89 | — | *W EXP 99/99/999 | G78516401 |
| — | PLX PHARMA INC | 57,459 | $793K | 0.0% | $13.80 | $9.03 | — | COM | 72942A107 |
| TKNO | ALPHA TEKNOVA INC | 30,000 | $712K | 0.0% | $23.73 * | $25.30 | 0.0% | COM | 02080L102 |
| — | TCR2 THERAPEUTICS INC | 30,753 | $505K | 0.0% | $16.42 | $20.32 | — | COM | 87808K106 |
| PHVS | PHARVARIS NV | 27,000 | $503K | 0.0% | $18.63 * | $31.46 | -27.9% | COM | N69605108 |
| — | CAREMAX INC | 60,000 | $283K | 0.0% | $4.72 | $4.72 | — | *W EXP 06/08/202 | 14171W111 |
| — | RAPT THERAPEUTICS INC | 45,000 | $83,000 | 0.0% | $1.84 | $20.64 | — | PUT | 75382E109 |