Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q2 2022 (← Previous) (Next →)
Filing Date: Aug 15, 2022
Total Value: $3.193B (84.8% shares, 15.2% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | TRAVERE THERAPEUTICS INC | 45,000,000 | $456M | 14.3% | $10.13 | $10.54 | — | NOTE 2.250% 3/0 | 89422GAA5 |
| FOLD | AMICUS THERAPEUTICS INC | 26,895,532 | $289M | 9.0% | $10.74 * | $7.24 | +13.7% | COM | 03152W109 |
| — | MIRATI THERAPEUTICS INC | 2,866,863 | $192M | 6.0% | $67.13 | $106.91 | — | COM | 60468T105 |
| — | CEREVEL THERAPEUTICS HLDNG I | 5,086,727 | $134M | 4.2% | $26.44 | $17.65 | — | COM | 15678U128 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 11,826,299 | $131M | 4.1% | $11.04 * | $16.03 | -18.3% | COM | 462260100 |
| LIANY | LIANBIO | 56,560,211 | $122M | 3.8% | $2.16 | $6.16 | — | SPONSORED ADS | 53000N108 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 5,321,032 | $99.24M | 3.1% | $18.65 * | $25.03 | -20.3% | COM | 22663K107 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 3,015,054 | $96.33M | 3.0% | $31.95 | $32.68 | — | COM | 37890U108 |
| — | SPRINGWORKS THERAPEUTICS INC | 3,867,446 | $95.22M | 3.0% | $24.62 | $36.75 | — | COM | 85205L107 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 3,540,408 | $68.19M | 2.1% | $19.26 * | $16.28 | -27.1% | COM | 03237H101 |
| XENE | XENON PHARMACEUTICALS INC | 2,122,535 | $64.57M | 2.0% | $30.42 | $19.81 | +52.6% | COM | 98420N105 |
| MGTX | MEIRAGTX HLDGS PLC | 6,963,277 | $52.71M | 1.7% | $7.57 * | $14.20 | -31.7% | COM | G59665102 |
| — | LYRA THERAPEUTICS INC | 9,146,730 | $51.68M | 1.6% | $5.65 | $7.65 | — | COM | 55234L105 |
| — | BELLUS HEALTH INC NEW | 5,534,169 | $51.14M | 1.6% | $9.24 | $7.98 | — | COM NEW | 07987C204 |
| — | PROMETHEUS BIOSCIENCES INC | 1,682,242 | $47.49M | 1.5% | $28.23 | $16.70 | — | COM | 74349U108 |
| — | ALBIREO PHARMA INC | 2,360,139 | $46.87M | 1.5% | $19.86 | $25.25 | — | COM | 01345P106 |
| — | CINCOR PHARMA INC | 2,319,117 | $43.69M | 1.4% | $18.84 | $17.54 | — | COM | 17240Y109 |
| — | VBI VACCINES INC CDA | 52,335,002 | $42.31M | 1.3% | $0.81 | $1.95 | — | COM NEW | 91822J103 |
| — | SEAGEN INC | 224,000 | $39.63M | 1.2% | $176.94 | $176.94 | — | COM | 81181C104 |
| — | VERU INC | 3,500,000 | $39.55M | 1.2% | $11.30 | $6.58 | — | COM | 92536C103 |
| ALDX | ALDEYRA THERAPEUTICS INC | 9,903,879 | $39.52M | 1.2% | $3.99 * | $8.42 | -59.2% | COM | 01438T106 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 397,888 | $38.79M | 1.2% | $97.48 * | $49.72 | +85.6% | COM | 64125C109 |
| — | RAPT THERAPEUTICS INC | 1,913,791 | $34.93M | 1.1% | $18.25 | $22.19 | — | COM | 75382E109 |
| RLAY | RELAY THERAPEUTICS INC | 1,943,097 | $32.55M | 1.0% | $16.75 * | $38.13 | -43.8% | COM | 75943R102 |
| LLY | LILLY ELI & CO | 100,000 | $32.42M | 1.0% | $324.23 * | $290.91 | 0.0% | COM | 532457108 |
| — | COHERUS BIOSCIENCES INC | 4,500,000 | $29.48M | 0.9% | $6.55 | $10.23 | — | NOTE 1.500% 4/1 | 19249HAB9 |
| COGT | COGENT BIOSCIENCES INC | 3,088,972 | $27.86M | 0.9% | $9.02 * | $10.99 | -37.9% | COM | 19240Q201 |
| CHRS | COHERUS BIOSCIENCES INC | 3,645,471 | $26.39M | 0.8% | $7.24 * | $18.09 | -51.9% | COM | 19249H103 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 367,501 | $26.31M | 0.8% | $71.58 * | $81.18 | -9.5% | COM | 558868105 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 172,991 | $25.23M | 0.8% | $145.85 * | $152.35 | -6.9% | COM | 02043Q107 |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | 9,111,151 | $24.51M | 0.8% | $2.69 * | $10.71 | -65.2% | COM | 63909J108 |
| PRCT | PROCEPT BIOROBOTICS CORP | 749,700 | $24.51M | 0.8% | $32.69 * | $36.84 | -1.3% | COM | 74276L105 |
| ADMA | ADMA BIOLOGICS INC | 11,521,102 | $22.81M | 0.7% | $1.98 | $4.00 | -50.8% | COM | 000899104 |
| NUVL | NUVALENT INC | 1,655,007 | $22.44M | 0.7% | $13.56 * | $20.73 | -49.0% | COM | 670703107 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 405,759 | $22.07M | 0.7% | $54.38 * | $36.86 | +72.2% | COM | G31249108 |
| — | ZYMEWORKS INC | 4,132,534 | $21.9M | 0.7% | $5.30 | $21.79 | — | COM | 98985W102 |
| IMTX | IMMATICS N.V | 2,500,000 | $21.77M | 0.7% | $8.71 * | $10.53 | -24.9% | SHS | N44445109 |
| — | INHIBRX INC | 1,914,592 | $21.73M | 0.7% | $11.35 | $27.72 | — | COM | 45720L107 |
| ACLX | ARCELLX INC | 1,141,990 | $20.65M | 0.6% | $18.08 * | $12.90 | 0.0% | COMMON STOCK | 03940C100 |
| — | IVERIC BIO INC | 2,087,956 | $20.09M | 0.6% | $9.62 | $10.04 | — | COM | 46583P102 |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | 411,804 | $20.08M | 0.6% | $48.77 * | $45.02 | 0.0% | COM | 413197104 |
| TARS | TARSUS PHARMACEUTICALS INC | 1,296,416 | $18.93M | 0.6% | $14.60 * | $28.48 | -47.3% | COM | 87650L103 |
| AORT | ARTIVION INC | 929,705 | $17.55M | 0.5% | $18.88 * | $19.60 | -1.6% | COM | 228903100 |
| — | DICE THERAPEUTICS INC | 1,051,904 | $16.33M | 0.5% | $15.52 | $22.00 | — | COM | 23345J104 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,166,883 | $16.06M | 0.5% | $13.76 * | $23.99 | -50.3% | COM | 77313F106 |
| BBIO | BRIDGEBIO PHARMA INC | 1,697,033 | $15.41M | 0.5% | $9.08 * | $32.43 | -74.2% | COM | 10806X102 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 180,000 | $14.92M | 0.5% | $82.87 * | $79.62 | 0.0% | COM | 09061G101 |
| — | OUTSET MED INC | 998,727 | $14.84M | 0.5% | $14.86 | $49.95 | — | COM | 690145107 |
| — | ATHIRA PHARMA INC | 4,797,278 | $14.63M | 0.5% | $3.05 | $14.05 | — | COM | 04746L104 |
| APLS | APELLIS PHARMACEUTICALS INC | 321,300 | $14.53M | 0.5% | $45.22 | $44.54 | +2.4% | COM | 03753U106 |
| TVTX | TRAVERE THERAPEUTICS INC | 570,084 | $13.81M | 0.4% | $24.23 * | $23.04 | +9.1% | COM | 89422G107 |
| — | RAIN THERAPEUTICS INC | 2,483,619 | $13.81M | 0.4% | $5.56 | $15.54 | — | COM | 75082Q105 |
| — | SINGULAR GENOMICS SYSTEMS IN | 3,536,274 | $13.51M | 0.4% | $3.82 | $24.49 | — | COM | 82933R100 |
| TMCI | TREACE MED CONCEPTS INC | 941,192 | $13.5M | 0.4% | $14.34 * | $31.83 | -47.1% | COM | 89455T109 |
| — | VERONA PHARMA PLC | 2,915,146 | $12.21M | 0.4% | $4.19 | $6.17 | — | SPONSORED ADS | 925050106 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 971,832 | $11.24M | 0.4% | $11.57 * | $16.03 | -16.2% | COM | 92790C104 |
| — | CHEMOCENTRYX INC | 441,680 | $10.95M | 0.3% | $24.78 | $28.35 | — | COM | 16383L106 |
| — | CAREMAX INC | 3,000,000 | $10.89M | 0.3% | $3.63 | $12.60 | — | COM CL A | 14171W103 |
| — | LANDOS BIOPHARMA INC | 14,869,915 | $10.82M | 0.3% | $0.73 | $9.48 | — | COM | 515069102 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 556,047 | $9.953M | 0.3% | $17.90 * | $20.76 | -50.3% | COM | 23954D109 |
| — | VERRICA PHARMACEUTICALS INC | 5,038,983 | $9.675M | 0.3% | $1.92 | $14.50 | — | COM | 92511W108 |
| — | LEAP THERAPEUTICS INC | 7,951,448 | $9.144M | 0.3% | $1.15 | $1.68 | — | COM | 52187K101 |
| — | CONCERT PHARMACEUTICALS INC | 2,150,641 | $9.054M | 0.3% | $4.21 | $12.16 | — | COM | 206022105 |
| — | ISOPLEXIS CORP | 4,095,498 | $8.846M | 0.3% | $2.16 | $9.19 | — | COM | 465005106 |
| — | KRONOS BIO INC | 2,421,142 | $8.812M | 0.3% | $3.64 | $29.87 | — | COM | 50107A104 |
| — | HILLEVAX INC | 764,907 | $8.36M | 0.3% | $10.93 | $10.93 | — | COM | 43157M102 |
| — | SOLID BIOSCIENCES INC | 13,412,552 | $8.257M | 0.3% | $0.62 | $4.84 | — | COM | 83422E105 |
| PRVA | PRIVIA HEALTH GROUP INC | 273,423 | $7.962M | 0.2% | $29.12 * | $24.01 | +5.9% | COM | 74276R102 |
| — | REVANCE THERAPEUTICS INC | 572,514 | $7.912M | 0.2% | $13.82 | $15.18 | — | COM | 761330109 |
| — | MORPHIC HLDG INC | 363,197 | $7.881M | 0.2% | $21.70 | $40.72 | — | COM | 61775R105 |
| XBI | SPDR SER TR | 100,000 | $7.427M | 0.2% | $74.27 | — | — | Put | 78464A870 |
| — | POINT BIOPHARMA GLOBAL INC | 1,073,995 | $7.314M | 0.2% | $6.81 | $7.69 | — | COM | 730541109 |
| — | SOMALOGIC INC | 1,500,000 | $6.78M | 0.2% | $4.52 | $12.39 | — | CLASS A COM | 83444K105 |
| HCAT | HEALTH CATALYST INC | 465,162 | $6.74M | 0.2% | $14.49 * | $42.38 | -59.8% | COM | 42225T107 |
| — | SEMA4 HOLDINGS CORP | 5,000,000 | $6.3M | 0.2% | $1.26 | $4.42 | — | COM CL A | 81663L101 |
| — | ICOSAVAX INC | 1,042,850 | $5.976M | 0.2% | $5.73 | $29.59 | — | COM | 45114M109 |
| CCCC | C4 THERAPEUTICS INC | 766,231 | $5.777M | 0.2% | $7.54 * | $29.00 | -69.7% | COM STK | 12529R107 |
| NUVB | NUVATION BIO INC | 1,769,701 | $5.733M | 0.2% | $3.24 * | $11.18 | -61.0% | COM CL A | 67080N101 |
| — | ATHENEX INC | 13,532,467 | $5.54M | 0.2% | $0.41 | $14.52 | — | COM | 04685N103 |
| ACRS | ACLARIS THERAPEUTICS INC | 341,239 | $4.764M | 0.1% | $13.96 | $20.30 | -31.0% | COM | 00461U105 |
| NBTX | NANOBIOTIX | 1,059,800 | $4.027M | 0.1% | $3.80 | $16.50 | — | SPONSORED ADS | 63009J107 |
| — | QUOTIENT LTD | 16,200,818 | $3.888M | 0.1% | $0.24 | $7.28 | — | SHS | G73268107 |
| — | ASTRIA THERAPEUTICS INC | 1,281,197 | $3.843M | 0.1% | $3.00 | $8.84 | — | COM | 04635X102 |
| PYXS | PYXIS ONCOLOGY INC | 1,528,812 | $3.639M | 0.1% | $2.38 * | $11.45 | -76.7% | COMMON STOCK | 747324101 |
| MGNX | MACROGENICS INC | 1,227,202 | $3.62M | 0.1% | $2.95 * | $20.23 | -74.0% | COM | 556099109 |
| TYRA | TYRA BIOSCIENCES INC | 494,403 | $3.535M | 0.1% | $7.15 * | $19.11 | -58.3% | COM | 90240B106 |
| CLOV | CLOVER HEALTH INVESTMENTS CO | 1,500,000 | $3.21M | 0.1% | $2.14 * | $11.28 | -76.4% | COM CL A | 18914F103 |
| — | Y-MABS THERAPEUTICS INC | 212,018 | $3.208M | 0.1% | $15.13 | $15.13 | — | COM | 984241109 |
| — | SCIENCE 37 HOLDINGS INC | 1,500,000 | $3.015M | 0.1% | $2.01 | $12.47 | — | COM | 808644108 |
| ABSI | ABSCI CORPORATION | 894,346 | $2.969M | 0.1% | $3.32 * | $19.41 | -74.4% | COM | 00091E109 |
| — | ENVVENO MEDICAL CORPORATION | 781,615 | $2.954M | 0.1% | $3.78 | $6.59 | — | COM | 29415J106 |
| SAVA | CASSAVA SCIENCES INC | 100,000 | $2.812M | 0.1% | $28.12 | — | — | Put | 14817C107 |
| — | FUSION PHARMACEUTICALS INC | 1,052,445 | $2.621M | 0.1% | $2.49 | $16.08 | — | COM | 36118A100 |
| HYPR | HYPERFINE INC | 1,134,388 | $2.53M | 0.1% | $2.23 * | $9.78 | -69.9% | COM CL A | 44916K106 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 508,532 | $2.39M | 0.1% | $4.70 * | $5.44 | -30.9% | COM | 00509G209 |
| RLMD | RELMADA THERAPEUTICS INC | 121,350 | $2.304M | 0.1% | $18.99 * | $20.68 | +5.5% | COM | 75955J402 |
| — | DARIOHEALTH CORP | 327,869 | $2.013M | 0.1% | $6.14 | $19.26 | — | COM NEW | 23725P209 |
| FULC | FULCRUM THERAPEUTICS INC | 294,118 | $1.441M | 0.0% | $4.90 * | $10.11 | -3.3% | COM | 359616109 |
| — | PEAR THERAPEUTICS INC | 900,548 | $1.386M | 0.0% | $1.54 | $6.20 | — | CLASS A COM | 704723105 |
| RACE | FERRARI N V | 6,200 | $1.138M | 0.0% | $183.55 * | $40.37 | +393.0% | COM | N3167Y103 |
| — | SONENDO INC | 648,505 | $1.115M | 0.0% | $1.72 | $5.76 | — | COM | 835431107 |
| — | ZYMERGEN INC | 883,332 | $1.086M | 0.0% | $1.23 | $40.01 | — | COM | 98985X100 |
| TARA | PROTARA THERAPEUTICS INC | 290,051 | $850K | 0.0% | $2.93 * | $23.19 | -84.2% | COM STK | 74365U107 |
| — | AGILE THERAPEUTICS INC | 532,361 | $620K | 0.0% | $1.16 | $1.16 | — | COM NEW | 00847L209 |
| — | MOTUS GI HLDGS INC | 1,800,542 | $507K | 0.0% | $0.28 | $4.01 | — | COM | 62014P108 |
| — | PROVENTION BIO INC | 110,728 | $443K | 0.0% | $4.00 | $13.33 | — | COM | 74374N102 |
| — | EQRX INC | 250,000 | $203K | 0.0% | $0.81 | $1.06 | — | *W EXP 12/17/202 | 26886C115 |
| — | NEPTUNE WELLNESS SOLUTIONS I | 57,142 | $81,000 | 0.0% | $1.42 | $1.42 | — | COM NEW | 64079L204 |
| — | CAREMAX INC | 60,000 | $43,000 | 0.0% | $0.72 | $4.72 | — | *W EXP 06/08/202 | 14171W111 |
| SRZNW | SURROZEN INC | 166,666 | $32,000 | 0.0% | $0.19 | $1.14 | — | *W EXP 08/01/203 | 86889P117 |
| — | SURROZEN INC | 6,017 | $18,000 | 0.0% | $2.99 | $7.08 | — | COM | 86889P109 |