Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q1 2022 (← Previous) (Next →)
Filing Date: May 16, 2022
Total Value: $4.992B (87.6% shares, 12.4% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | TRAVERE THERAPEUTICS INC | 45,000,000 | $474M | 9.5% | $10.54 | $10.54 | — | NOTE 2.250% 3/0 | 89422GAA5 |
| FOLD | AMICUS THERAPEUTICS INC | 27,555,845 | $261M | 5.2% | $9.47 | $7.24 | +29.4% | COM | 03152W109 |
| — | SPRINGWORKS THERAPEUTICS INC | 4,527,993 | $256M | 5.1% | $56.44 | $36.75 | — | COM | 85205L107 |
| LIANY | LIANBIO | 56,319,960 | $209M | 4.2% | $3.71 | $6.16 | — | SPONSORED ADS | 53000N108 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 12,201,261 | $203M | 4.1% | $16.65 * | $16.03 | -3.5% | COM | 462260100 |
| — | MIRATI THERAPEUTICS INC | 2,380,710 | $196M | 3.9% | $82.22 | $115.03 | — | COM | 60468T105 |
| — | AGILE THERAPEUTICS INC | 21,294,485 | $178M | 3.6% | $8.38 | $1.34 | — | COM | 00847L100 |
| — | CEREVEL THERAPEUTICS HLDNG I | 5,086,727 | $178M | 3.6% | $35.01 | $17.65 | — | COM | 15678U128 |
| — | HORIZON THERAPEUTICS PLC | 1,357,903 | $143M | 2.9% | $105.21 | $73.15 | — | SHS | G46188101 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 3,892,493 | $135M | 2.7% | $34.64 | $32.68 | — | COM | 37890U108 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 5,163,517 | $113M | 2.3% | $21.95 * | $25.18 | -19.6% | COM | 22663K107 |
| MGTX | MEIRAGTX HLDGS PLC | 6,948,277 | $96.2M | 1.9% | $13.85 * | $14.20 | +8.5% | COM | G59665102 |
| — | PROMETHEUS BIOSCIENCES INC | 2,440,582 | $92.16M | 1.8% | $37.76 | $16.70 | — | COM | 74349U108 |
| — | COLLEGIUM PHARMACEUTICAL INC | 9,500,000 | $89.47M | 1.8% | $9.42 | $8.98 | — | NOTE 2.625% 2/1 | 19459JAA2 |
| — | IVERIC BIO INC | 5,225,415 | $87.94M | 1.8% | $16.83 | $10.04 | — | COM | 46583P102 |
| — | VBI VACCINES INC CDA | 52,335,002 | $86.88M | 1.7% | $1.66 | $1.95 | — | COM NEW | 91822J103 |
| — | OUTSET MED INC | 1,883,399 | $85.51M | 1.7% | $45.40 | $49.95 | — | COM | 690145107 |
| APLS | APELLIS PHARMACEUTICALS INC | 1,481,700 | $75.28M | 1.5% | $50.81 * | $44.54 | -0.9% | COM | 03753U106 |
| XENE | XENON PHARMACEUTICALS INC | 2,411,447 | $73.72M | 1.5% | $30.57 * | $19.81 | +51.1% | COM | 98420N105 |
| — | ALBIREO PHARMA INC | 2,360,139 | $70.4M | 1.4% | $29.83 | $25.25 | — | COM | 01345P106 |
| — | RAPT THERAPEUTICS INC | 2,799,962 | $61.57M | 1.2% | $21.99 | $22.19 | — | COM | 75382E109 |
| CHRS | COHERUS BIOSCIENCES INC | 4,695,848 | $60.62M | 1.2% | $12.91 | $18.09 | -29.7% | COM | 19249H103 |
| RLAY | RELAY THERAPEUTICS INC | 1,943,097 | $58.16M | 1.2% | $29.93 * | $38.13 | -36.4% | COM | 75943R102 |
| — | BELLUS HEALTH INC NEW | 8,136,630 | $55.98M | 1.1% | $6.88 | $7.98 | — | COM NEW | 07987C204 |
| PRCT | PROCEPT BIOROBOTICS CORP | 1,488,284 | $52.08M | 1.0% | $34.99 * | $36.84 | -34.7% | COM | 74276L105 |
| CCCC | C4 THERAPEUTICS INC | 2,082,723 | $50.53M | 1.0% | $24.26 | $29.00 | -16.3% | COM STK | 12529R107 |
| TVTX | TRAVERE THERAPEUTICS INC | 1,845,555 | $47.56M | 1.0% | $25.77 * | $23.04 | +15.2% | COM | 89422G107 |
| — | ATHIRA PHARMA INC | 3,425,916 | $46.25M | 0.9% | $13.50 | $18.45 | — | COM | 04746L104 |
| — | COHERUS BIOSCIENCES INC | 4,500,000 | $44.6M | 0.9% | $9.91 | $10.23 | — | NOTE 1.500% 4/1 | 19249HAB9 |
| ALDX | ALDEYRA THERAPEUTICS INC | 9,903,879 | $44.02M | 0.9% | $4.45 * | $8.42 | -52.7% | COM | 01438T106 |
| — | CHEMOCENTRYX INC | 1,655,079 | $41.49M | 0.8% | $25.07 | $28.35 | — | COM | 16383L106 |
| — | CINCOR PHARMA INC | 2,319,117 | $40.68M | 0.8% | $17.54 | $17.54 | — | COM | 17240Y109 |
| — | INHIBRX INC | 1,781,235 | $39.69M | 0.8% | $22.28 | $28.94 | — | COM | 45720L107 |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | 9,111,151 | $39.54M | 0.8% | $4.34 * | $10.71 | -61.7% | COM | 63909J108 |
| BBIO | BRIDGEBIO PHARMA INC | 3,839,380 | $38.97M | 0.8% | $10.15 | $32.43 | -68.4% | COM | 10806X102 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 395,639 | $37.09M | 0.7% | $93.75 * | $49.72 | +70.5% | COM | 64125C109 |
| — | ZYMEWORKS INC | 5,325,615 | $34.88M | 0.7% | $6.55 | $21.79 | — | COM | 98985W102 |
| — | NEVRO CORP | 477,037 | $34.5M | 0.7% | $72.33 | $73.16 | — | COM | 64157F103 |
| PEN | PENUMBRA INC | 143,591 | $31.9M | 0.6% | $222.13 | $222.19 | 0.0% | COM | 70975L107 |
| — | MORPHIC HLDG INC | 767,327 | $30.81M | 0.6% | $40.15 | $40.72 | — | COM | 61775R105 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 450,374 | $30.35M | 0.6% | $67.39 * | $36.86 | +58.6% | COM | G31249108 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 180,079 | $29.41M | 0.6% | $163.29 * | $152.35 | 0.0% | COM | 02043Q107 |
| — | VERRICA PHARMACEUTICALS INC | 3,610,412 | $29.28M | 0.6% | $8.11 | $19.48 | — | COM | 92511W108 |
| — | DICE THERAPEUTICS INC | 1,515,361 | $28.99M | 0.6% | $19.13 | $22.00 | — | COM | 23345J104 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 278,286 | $27.3M | 0.5% | $98.12 * | $83.64 | +0.8% | COM | 558868105 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,678,090 | $26.61M | 0.5% | $15.86 * | $23.99 | -28.0% | COM | 77313F106 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 1,423,053 | $26.31M | 0.5% | $18.49 * | $16.03 | +19.8% | COM | 92790C104 |
| NUVL | NUVALENT INC | 1,751,601 | $24.33M | 0.5% | $13.89 * | $20.73 | -29.9% | COM | 670703107 |
| COGT | COGENT BIOSCIENCES INC | 3,188,750 | $23.88M | 0.5% | $7.49 * | $10.99 | -36.6% | COM | 19240Q201 |
| — | CAREMAX INC | 3,186,663 | $23.8M | 0.5% | $7.47 | $12.60 | — | COM CL A | 14171W103 |
| ZNTL | ZENTALIS PHARMACEUTICALS INC | 501,509 | $23.14M | 0.5% | $46.14 * | $74.06 | -27.2% | COM | 98943L107 |
| — | SINGULAR GENOMICS SYSTEMS IN | 3,655,207 | $23.06M | 0.5% | $6.31 | $24.49 | — | COM | 82933R100 |
| LEGN | LEGEND BIOTECH CORP | 616,141 | $22.39M | 0.4% | $36.34 | $39.49 | — | SPONSORED ADS | 52490G102 |
| — | LANDOS BIOPHARMA INC | 14,869,915 | $21.93M | 0.4% | $1.47 | $9.48 | — | COM | 515069102 |
| ADMA | ADMA BIOLOGICS INC | 11,933,387 | $21.84M | 0.4% | $1.83 * | $4.00 | -61.0% | COM | 000899104 |
| TARS | TARSUS PHARMACEUTICALS INC | 1,296,416 | $21.8M | 0.4% | $16.82 * | $28.48 | -34.9% | COM | 87650L103 |
| — | AXONICS INC | 341,211 | $21.36M | 0.4% | $62.60 | $62.60 | — | COM | 05465P101 |
| — | VERU INC | 4,361,998 | $21.07M | 0.4% | $4.83 | $6.58 | — | COM | 92536C103 |
| IMTX | IMMATICS N.V | 2,500,000 | $19.98M | 0.4% | $7.99 * | $10.53 | -13.5% | SHS | N44445109 |
| — | QUOTIENT LTD | 16,200,818 | $19.44M | 0.4% | $1.20 | $7.28 | — | SHS | G73268107 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 1,474,107 | $18.94M | 0.4% | $12.85 * | $22.45 | 0.0% | COM | 03237H101 |
| TMCI | TREACE MED CONCEPTS INC | 971,192 | $18.36M | 0.4% | $18.91 * | $31.83 | -38.9% | COM | 89455T109 |
| — | KRONOS BIO INC | 2,421,142 | $17.5M | 0.4% | $7.23 | $29.87 | — | COM | 50107A104 |
| — | SOLID BIOSCIENCES INC | 13,412,552 | $16.09M | 0.3% | $1.20 | $4.84 | — | COM | 83422E105 |
| — | VERONA PHARMA PLC | 3,044,303 | $15.19M | 0.3% | $4.99 | $6.17 | — | SPONSORED ADS | 925050106 |
| — | ISOPLEXIS CORP | 4,095,498 | $14.05M | 0.3% | $3.43 | $9.19 | — | COM | 465005106 |
| — | LEAP THERAPEUTICS INC | 7,951,448 | $13.91M | 0.3% | $1.75 | $1.68 | — | COM | 52187K101 |
| MGNX | MACROGENICS INC | 1,559,789 | $13.74M | 0.3% | $8.81 * | $20.23 | -45.4% | COM | 556099109 |
| LUNG | PULMONX CORP | 537,779 | $13.34M | 0.3% | $24.81 * | $36.52 | -29.3% | COM | 745848101 |
| AORT | ARTIVION INC | 615,703 | $13.16M | 0.3% | $21.38 * | $19.77 | -2.3% | COM | 228903100 |
| — | LYRA THERAPEUTICS INC | 3,222,560 | $12.96M | 0.3% | $4.02 | $11.34 | — | COM | 55234L105 |
| HCAT | HEALTH CATALYST INC | 493,662 | $12.9M | 0.3% | $26.13 * | $42.38 | -33.1% | COM | 42225T107 |
| RCUS | ARCUS BIOSCIENCES INC | 405,000 | $12.78M | 0.3% | $31.56 * | $33.51 | 0.0% | COM | 03969F109 |
| — | RAIN THERAPEUTICS INC | 2,483,619 | $12.59M | 0.3% | $5.07 | $15.54 | — | COM | 75082Q105 |
| — | SOMALOGIC INC | 1,500,000 | $12.03M | 0.2% | $8.02 | $12.39 | — | CLASS A COM | 83444K105 |
| — | ATHENEX INC | 13,532,467 | $11.22M | 0.2% | $0.83 | $14.52 | — | COM | 04685N103 |
| — | NANOSTRING TECHNOLOGIES INC | 1,000,000 | $11.04M | 0.2% | $11.04 | $16.19 | — | NOTE 2.625% 3/0 | 63009RAD1 |
| HLTHQ | CUE HEALTH INC | 1,580,607 | $10.2M | 0.2% | $6.45 | $11.81 | — | COM | 229790100 |
| ABSI | ABSCI CORPORATION | 1,190,952 | $10.04M | 0.2% | $8.43 * | $19.41 | -59.5% | COM | 00091E109 |
| — | BCLS ACQUISITION CORP | 1,000,000 | $9.87M | 0.2% | $9.87 | $11.14 | — | COM CL A | G0904B105 |
| — | SUMMIT HEALTHCRE ACQUISTN CO | 1,000,000 | $9.777M | 0.2% | $9.78 | $10.01 | — | UNIT 06/03/2026 | G8566R128 |
| — | RESEARCH ALLIANCE CORP II | 1,000,000 | $9.76M | 0.2% | $9.76 | $10.25 | — | COM CL A | 760873109 |
| — | ICOSAVAX INC | 1,379,137 | $9.709M | 0.2% | $7.04 | $29.59 | — | COM | 45114M109 |
| — | FUSION PHARMACEUTICALS INC | 1,227,017 | $9.534M | 0.2% | $7.77 | $16.08 | — | COM | 36118A100 |
| — | POINT BIOPHARMA GLOBAL INC | 1,193,995 | $9.516M | 0.2% | $7.97 | $7.69 | — | COM | 730541109 |
| NUVB | NUVATION BIO INC | 1,769,701 | $9.308M | 0.2% | $5.26 * | $11.18 | -49.8% | COM CL A | 67080N101 |
| — | ASTRIA THERAPEUTICS INC | 1,281,197 | $8.596M | 0.2% | $6.71 | $8.84 | — | COM | 04635X102 |
| EVH | EVOLENT HEALTH INC | 250,000 | $8.075M | 0.2% | $32.30 * | $26.18 | 0.0% | CL A | 30050B101 |
| — | SCIENCE 37 HOLDINGS INC | 1,500,000 | $8.025M | 0.2% | $5.35 | $12.47 | — | COM | 808644108 |
| NBTX | NANOBIOTIX SA | 1,059,800 | $7.885M | 0.2% | $7.44 | $16.50 | — | SPONSORED ADS | 63009J107 |
| — | SEMA4 HOLDINGS CORP | 2,500,000 | $7.675M | 0.2% | $3.07 | $7.59 | — | COM CL A | 81663L101 |
| — | CONCERT PHARMACEUTICALS INC | 2,150,641 | $7.247M | 0.1% | $3.37 | $12.16 | — | COM | 206022105 |
| FULC | FULCRUM THERAPEUTICS INC | 294,118 | $6.956M | 0.1% | $23.65 * | $10.11 | +40.0% | COM | 359616109 |
| ACAD | ACADIA PHARMACEUTICALS INC | 284,853 | $6.899M | 0.1% | $24.22 | $20.11 | +20.3% | COM | 004225108 |
| ACRS | ACLARIS THERAPEUTICS INC | 383,239 | $6.607M | 0.1% | $17.24 * | $20.30 | -32.8% | COM | 00461U105 |
| PYXS | PYXIS ONCOLOGY INC | 1,528,812 | $6.176M | 0.1% | $4.04 * | $11.45 | -36.2% | COMMON STOCK | 747324101 |
| — | ACCOLADE INC | 330,682 | $5.807M | 0.1% | $17.56 | $34.08 | — | COM | 00437E102 |
| — | PROVENTION BIO INC | 791,549 | $5.794M | 0.1% | $7.32 | $13.33 | — | COM | 74374N102 |
| PRVA | PRIVIA HEALTH GROUP INC | 213,423 | $5.705M | 0.1% | $26.73 * | $23.61 | 0.0% | COM | 74276R102 |
| — | MERUS N V | 209,046 | $5.527M | 0.1% | $26.44 | $31.80 | — | COM | N5749R100 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 556,047 | $5.516M | 0.1% | $9.92 * | $20.76 | -36.4% | COM | 23954D109 |
| CLOV | CLOVER HEALTH INVESTMENTS CO | 1,500,000 | $5.325M | 0.1% | $3.55 * | $11.28 | -74.3% | COM CL A | 18914F103 |
| HYPR | HYPERFINE INC | 1,500,000 | $5.31M | 0.1% | $3.54 * | $9.78 | -57.8% | COM CL A | 44916K106 |
| TYRA | TYRA BIOSCIENCES INC | 494,403 | $5.29M | 0.1% | $10.70 * | $19.11 | -37.9% | COM | 90240B106 |
| — | ENVVENO MEDICAL CORPORATION | 781,615 | $4.978M | 0.1% | $6.37 | $6.59 | — | COM | 29415J106 |
| — | DA32 LIFE SCNCE TEC ACQSTN C | 500,000 | $4.858M | 0.1% | $9.72 | $9.83 | — | CLASS A COM | 23312M106 |
| — | PEAR THERAPEUTICS INC | 926,232 | $4.677M | 0.1% | $5.05 | $6.20 | — | CLASS A COM | 704723105 |
| SGHT | SIGHT SCIENCES INC | 390,000 | $4.508M | 0.1% | $11.56 * | $32.87 | -53.2% | COM | 82657M105 |
| — | HEALTH SCIENCES ACQ CORP 2 | 450,000 | $4.46M | 0.1% | $9.91 | $11.00 | — | ORD SHS | G4411D109 |
| — | INVITAE CORP | 554,585 | $4.42M | 0.1% | $7.97 | $41.81 | — | COM | 46185L103 |
| IMRX | IMMUNEERING CORP | 681,051 | $4.406M | 0.1% | $6.47 * | $26.87 | -64.3% | CLASS A COM | 45254E107 |
| RLMD | RELMADA THERAPEUTICS INC | 151,350 | $4.085M | 0.1% | $26.99 * | $20.68 | 0.0% | COM | 75955J402 |
| — | INARI MED INC | 30,000 | $2.719M | 0.1% | $90.63 | $90.63 | — | COM | 45332Y109 |
| — | REVANCE THERAPEUTICS INC | 137,514 | $2.682M | 0.1% | $19.50 | $19.50 | — | COM | 761330109 |
| — | SONENDO INC | 668,505 | $2.681M | 0.1% | $4.01 | $5.76 | — | COM | 835431107 |
| — | ZYMERGEN INC | 883,332 | $2.553M | 0.1% | $2.89 | $40.01 | — | COM | 98985X100 |
| PRTA | PROTHENA CORP PLC | 65,144 | $2.382M | 0.0% | $36.57 | $31.20 | +15.5% | SHS | G72800108 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 596,942 | $2.334M | 0.0% | $3.91 * | $5.44 | 0.0% | COM | 00509G209 |
| TARA | PROTARA THERAPEUTICS INC | 383,526 | $1.96M | 0.0% | $5.11 * | $23.19 | -77.3% | COM STK | 74365U107 |
| — | DARIOHEALTH CORP | 327,869 | $1.915M | 0.0% | $5.84 | $19.26 | — | COM NEW | 23725P209 |
| — | GRAPHITE BIO INC | 325,854 | $1.662M | 0.0% | $5.10 | $30.73 | — | COM | 38870X104 |
| — | REATA PHARMACEUTICALS INC | 44,475 | $1.457M | 0.0% | $32.76 | $32.76 | — | CL A | 75615P103 |
| RACE | FERRARI N V | 6,200 | $1.352M | 0.0% | $218.06 * | $40.37 | +453.1% | COM | N3167Y103 |
| — | ONCORUS INC | 752,241 | $1.339M | 0.0% | $1.78 | $32.33 | — | COM | 68236R103 |
| RPID | RAPID MICRO BIOSYSTEMS INC | 190,745 | $1.295M | 0.0% | $6.79 * | $20.19 | -63.5% | CLASS A COM | 75340L104 |
| — | MOTUS GI HLDGS INC | 1,800,542 | $648K | 0.0% | $0.36 | $4.01 | — | COM | 62014P108 |
| — | NEPTUNE WELLNESS SOLUTIONS I | 2,000,000 | $445K | 0.0% | $0.22 | $3.20 | — | COM | 64079L105 |
| — | ROCKLEY PHOTONICS HOLDINGS L | 500,000 | $425K | 0.0% | $0.85 | $2.39 | — | *W EXP 08/11/202 | G7614L117 |
| BFLYW | BUTTERFLY NETWORK INC | 233,333 | $238K | 0.0% | $1.02 | $6.45 | — | *W EXP 02/12/202 | 124155110 |
| — | SOMALOGIC INC | 110,000 | $235K | 0.0% | $2.14 | $3.45 | — | *W EXP 08/31/202 | 83444K113 |
| — | SURROZEN INC | 77,723 | $234K | 0.0% | $3.01 | $7.08 | — | COM | 86889P109 |
| — | MINERVA SURGICAL INC | 50,268 | $226K | 0.0% | $4.50 | $5.14 | — | COM | 60343F106 |
| — | EQRX INC | 250,000 | $218K | 0.0% | $0.87 | $1.06 | — | *W EXP 12/17/202 | 26886C115 |
| — | CAREMAX INC | 60,000 | $114K | 0.0% | $1.90 | $4.72 | — | *W EXP 06/08/202 | 14171W111 |
| SRZNW | SURROZEN INC | 166,666 | $42,000 | 0.0% | $0.25 | $1.14 | — | *W EXP 08/01/203 | 86889P117 |