Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q2 2023 (← Previous) (Next →)
Filing Date: Aug 24, 2023
Total Value: $3.455B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| FOLD | AMICUS THERAPEUTICS INC | 27,662,917 | $347M | 10.1% | $12.56 * | $7.31 | +62.3% | COM | 03152W109 |
| — | CEREVEL THERAPEUTICS HLDNG I | 10,088,385 | $321M | 9.3% | $31.79 | $24.16 | — | COM | 15678U128 |
| LIANY | LIANBIO | 57,558,451 | $131M | 3.8% | $2.28 | $6.09 | — | SPONSORED ADS | 53000N108 |
| ACLX | ARCELLX INC | 4,016,397 | $127M | 3.7% | $31.62 * | $21.79 | +75.5% | COMMON STOCK | 03940C100 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 4,873,919 | $105M | 3.0% | $21.57 * | $20.97 | +28.8% | COM | 03237H101 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 14,036,410 | $98.82M | 2.9% | $7.04 | $12.84 | -44.2% | COM | 462260100 |
| ALDX | ALDEYRA THERAPEUTICS INC | 11,350,085 | $95.23M | 2.8% | $8.39 * | $8.11 | +21.4% | COM | 01438T106 |
| — | INHIBRX INC | 3,624,182 | $94.08M | 2.7% | $25.96 | $23.99 | — | COM | 45720L107 |
| — | VERONA PHARMA PLC | 4,397,116 | $92.96M | 2.7% | $21.14 | $12.90 | — | SPONSORED ADS | 925050106 |
| NUVL | NUVALENT INC | 2,194,821 | $92.56M | 2.7% | $42.17 * | $22.77 | +66.0% | COM | 670703107 |
| — | AKERO THERAPEUTICS INC | 1,940,675 | $90.61M | 2.6% | $46.69 | $43.66 | — | COM | 00973Y108 |
| PCVX | VAXCYTE INC | 1,614,122 | $80.61M | 2.3% | $49.94 * | $41.49 | +14.3% | COM | 92243G108 |
| MGTX | MEIRAGTX HLDGS PLC | 11,331,103 | $76.15M | 2.2% | $6.72 * | $11.20 | -42.6% | COM | G59665102 |
| APLS | APELLIS PHARMACEUTICALS INC | 812,037 | $73.98M | 2.1% | $91.10 * | $66.74 | +29.3% | COM | 03753U106 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 302,987 | $69.99M | 2.0% | $231.00 * | $90.28 | +200.0% | COM | 558868105 |
| — | REATA PHARMACEUTICALS INC | 670,206 | $68.33M | 2.0% | $101.96 | $90.92 | — | CL A | 75615P103 |
| TMCI | TREACE MED CONCEPTS INC | 2,217,250 | $56.72M | 1.6% | $25.58 | $25.52 | +1.2% | COM | 89455T109 |
| — | LYRA THERAPEUTICS INC | 12,757,562 | $52.43M | 1.5% | $4.11 | $6.65 | — | COM | 55234L105 |
| VIR | VIR BIOTECHNOLOGY INC | 1,958,264 | $48.04M | 1.4% | $24.53 * | $25.15 | -0.1% | COM | 92764N102 |
| IMVT | IMMUNOVANT INC | 2,523,783 | $47.88M | 1.4% | $18.97 | $17.70 | +5.3% | COM | 45258J102 |
| XENE | XENON PHARMACEUTICALS INC | 1,223,377 | $47.1M | 1.4% | $38.50 * | $19.81 | +100.6% | COM | 98420N105 |
| ADMA | ADMA BIOLOGICS INC | 11,900,255 | $43.91M | 1.3% | $3.69 | $3.92 | -5.5% | COM | 000899104 |
| — | RAPT THERAPEUTICS INC | 2,288,493 | $42.79M | 1.2% | $18.70 | $21.27 | — | COM | 75382E109 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 1,776,386 | $42.26M | 1.2% | $23.79 * | $21.18 | +21.1% | COM | 92790C104 |
| MDT | MEDTRONIC PLC | 467,000 | $41.14M | 1.2% | $88.10 * | $79.38 | 0.0% | SHS | G5960L103 |
| — | CYMABAY THERAPEUTICS INC | 3,733,255 | $40.88M | 1.2% | $10.95 | $8.27 | — | COM | 23257D103 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 1,469,761 | $40.59M | 1.2% | $27.62 * | $19.62 | +27.6% | COM | 74366E102 |
| — | SPRINGWORKS THERAPEUTICS INC | 1,537,431 | $40.31M | 1.2% | $26.22 | $36.75 | — | COM | 85205L107 |
| IMTX | IMMATICS N.V | 3,491,500 | $40.29M | 1.2% | $11.54 * | $10.48 | -10.9% | SHS | N44445109 |
| ACRV | ACRIVON THERAPEUTICS INC | 3,007,858 | $38.98M | 1.1% | $12.96 * | $12.69 | -4.7% | COMMON STOCK | 004890109 |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | 9,111,151 | $35.26M | 1.0% | $3.87 * | $10.71 | -73.1% | COM | 63909J108 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 1,946,937 | $35.08M | 1.0% | $18.02 * | $25.03 | -20.3% | COM | 22663K107 |
| IRON | DISC MEDICINE INC | 742,838 | $32.98M | 1.0% | $44.40 * | $35.48 | 0.0% | COM | 254604101 |
| ROIV | ROIVANT SCIENCES LTD | 3,131,736 | $31.57M | 0.9% | $10.08 * | $6.64 | +34.6% | SHS | G76279101 |
| COGT | COGENT BIOSCIENCES INC | 2,659,470 | $31.49M | 0.9% | $11.84 * | $11.14 | +3.0% | COM | 19240Q201 |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | 891,370 | $31.37M | 0.9% | $35.19 | $35.70 | -3.3% | COM | 413197104 |
| BBIO | BRIDGEBIO PHARMA INC | 1,748,933 | $30.08M | 0.9% | $17.20 * | $30.14 | -50.1% | COM | 10806X102 |
| ESTA | ESTABLISHMENT LABS HLDGS INC | 424,924 | $29.15M | 0.8% | $68.61 | $43.69 | +58.1% | COM | G31249108 |
| — | VERRICA PHARMACEUTICALS INC | 5,038,983 | $29.07M | 0.8% | $5.77 | $14.50 | — | COM | 92511W108 |
| ILMN | ILLUMINA INC | 145,000 | $27.19M | 0.8% | $187.49 * | $202.41 | 0.0% | COM | 452327109 |
| ARGX | ARGENX SE | 69,000 | $26.89M | 0.8% | $389.73 | $389.73 | — | SPONSORED ADR | 04016X101 |
| — | MIRATI THERAPEUTICS INC | 719,103 | $25.98M | 0.8% | $36.13 | $106.91 | — | COM | 60468T105 |
| RLAY | RELAY THERAPEUTICS INC | 1,943,097 | $24.41M | 0.7% | $12.56 | $38.13 | -67.4% | COM | 75943R102 |
| TARS | TARSUS PHARMACEUTICALS INC | 1,296,416 | $23.43M | 0.7% | $18.07 * | $28.48 | -44.2% | COM | 87650L103 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,168,363 | $23.22M | 0.7% | $19.87 | $20.80 | -2.8% | COM | 77313F106 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 263,207 | $22.81M | 0.7% | $86.68 * | $91.36 | +3.0% | COM | 09061G101 |
| ZYME | ZYMEWORKS INC | 2,416,232 | $20.88M | 0.6% | $8.64 * | $7.03 | +27.4% | COM | 98985Y108 |
| CABA | CABALETTA BIO INC | 1,545,000 | $19.95M | 0.6% | $12.91 * | $8.98 | +20.9% | COM | 12674W109 |
| — | OUTSET MED INC | 902,360 | $19.73M | 0.6% | $21.87 | $45.00 | — | COM | 690145107 |
| NTRA | NATERA INC | 405,269 | $19.72M | 0.6% | $48.66 * | $47.83 | +6.7% | COM | 632307104 |
| AXSM | AXSOME THERAPEUTICS INC | 271,493 | $19.51M | 0.6% | $71.86 * | $73.77 | 0.0% | COM | 05464T104 |
| SLDB | SOLID BIOSCIENCES INC | 3,495,933 | $18.32M | 0.5% | $5.24 * | $6.55 | -14.1% | COM NEW | 83422E204 |
| — | ASTRIA THERAPEUTICS INC | 2,189,462 | $18.24M | 0.5% | $8.33 | $11.35 | — | COM | 04635X102 |
| AORT | ARTIVION INC | 931,352 | $16.01M | 0.5% | $17.19 * | $19.72 | -25.3% | COM | 228903100 |
| BMEA | BIOMEA FUSION INC | 716,441 | $15.73M | 0.5% | $21.95 * | $22.74 | +37.7% | COM | 09077A106 |
| — | INTRA-CELLULAR THERAPIES INC | 245,800 | $15.56M | 0.5% | $63.32 | $63.32 | — | COM | 46116X101 |
| MIRM | MIRUM PHARMACEUTICALS INC | 601,566 | $15.56M | 0.5% | $25.87 * | $22.79 | +16.7% | COM | 604749101 |
| TCMD | TACTILE SYS TECHNOLOGY INC | 602,377 | $15.02M | 0.4% | $24.93 * | $13.93 | +49.2% | COM | 87357P100 |
| OBIO | ORCHESTRA BIOMED HLDGS INC | 2,052,868 | $14.37M | 0.4% | $7.00 * | $11.58 | +31.0% | COM | 68572M106 |
| — | ATHIRA PHARMA INC | 4,797,278 | $14.15M | 0.4% | $2.95 | $14.05 | — | COM | 04746L104 |
| AXGN | AXOGEN INC | 1,464,822 | $13.37M | 0.4% | $9.13 * | $10.29 | -9.4% | COM | 05463X106 |
| — | FUSION PHARMACEUTICALS INC | 2,751,395 | $12.85M | 0.4% | $4.67 | $3.77 | — | COM | 36118A100 |
| PRTA | PROTHENA CORP PLC | 184,615 | $12.61M | 0.4% | $68.28 * | $32.48 | +98.6% | SHS | G72800108 |
| — | CAREMAX INC | 3,817,404 | $11.87M | 0.3% | $3.11 | $10.31 | — | COM CL A | 14171W103 |
| SLNO | SOLENO THERAPEUTICS INC | 2,207,753 | $9.471M | 0.3% | $4.29 | $4.30 | 0.0% | COM | 834203309 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 100,050 | $9.435M | 0.3% | $94.30 * | $49.72 | +96.5% | COM | 64125C109 |
| TERN | TERNS PHARMACEUTICALS INC | 1,075,000 | $9.406M | 0.3% | $8.75 * | $9.56 | +22.0% | Put | 880881107 |
| SRPT | SAREPTA THERAPEUTICS INC | 81,074 | $9.285M | 0.3% | $114.52 * | $110.00 | +17.1% | COM | 803607100 |
| BHVN | BIOHAVEN LTD | 320,820 | $7.674M | 0.2% | $23.92 * | $17.21 | 0.0% | COM | G1110E107 |
| VKTX | VIKING THERAPEUTICS INC | 441,147 | $7.151M | 0.2% | $16.21 * | $10.33 | +102.8% | COM | 92686J106 |
| — | X4 PHARMACEUTICALS INC | 3,545,454 | $6.878M | 0.2% | $1.94 | $0.87 | — | COM | 98420X103 |
| — | IVERIC BIO INC | 168,000 | $6.609M | 0.2% | $39.34 | $10.04 | — | COM | 46583P102 |
| — | LANDOS BIOPHARMA INC | 1,486,991 | $6.256M | 0.2% | $4.21 | $4.21 | — | COM NEW | 515069201 |
| TYRA | TYRA BIOSCIENCES INC | 360,000 | $6.131M | 0.2% | $17.03 * | $19.11 | -24.1% | COM | 90240B106 |
| NBTX | NANOBIOTIX | 1,059,800 | $5.373M | 0.2% | $5.07 | $16.50 | — | SPONSORED ADS | 63009J107 |
| — | VBI VACCINES INC CDA | 1,381,355 | $4.545M | 0.1% | $3.29 | $3.29 | — | COM NEW | 91822J202 |
| — | ACELYRIN INC | 200,000 | $4.18M | 0.1% | $20.90 | $20.90 | — | COM | 00445A100 |
| — | SOMALOGIC INC | 1,500,000 | $3.465M | 0.1% | $2.31 | $12.39 | — | CLASS A COM | 83444K105 |
| — | KRONOS BIO INC | 1,752,745 | $3.015M | 0.1% | $1.72 | $29.87 | — | COM | 50107A104 |
| QTRX | QUANTERIX CORP | 130,000 | $2.932M | 0.1% | $22.55 * | $12.78 | +39.5% | COM | 74766Q101 |
| — | ENVVENO MEDICAL CORPORATION | 781,615 | $2.407M | 0.1% | $3.08 | $6.59 | — | COM | 29415J106 |
| — | SINGULAR GENOMICS SYSTEMS IN | 2,363,214 | $1.961M | 0.1% | $0.83 | $24.49 | — | COM | 82933R100 |
| CYPH | LEAP THERAPEUTICS INC | 586,733 | $1.836M | 0.1% | $3.13 * | $5.02 | 0.0% | COM NEW | 52187K200 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 300,000 | $1.417M | 0.0% | $4.72 | — | — | Put | 03969K108 |
| TVTX | TRAVERE THERAPEUTICS INC | 90,748 | $1.394M | 0.0% | $15.36 * | $23.04 | -21.1% | COM | 89422G107 |
| — | MIRATI THERAPEUTICS INC | 200,000 | $690K | 0.0% | $3.45 | $106.91 | — | Call | 60468T105 |
| — | POINT BIOPHARMA GLOBAL INC | 500,000 | $675K | 0.0% | $1.35 | — | — | Put | 730541109 |
| — | VERONA PHARMA PLC | 500,000 | $675K | 0.0% | $1.35 | $12.90 | — | Call | 925050106 |
| XBI | SPDR SER TR | 150,000 | $138K | 0.0% | $0.92 | — | — | Put | 78464A870 |
| — | VERU INC | 89,878 | $107K | 0.0% | $1.19 | $6.17 | — | COM | 92536C103 |
| — | MOTUS GI HLDGS INC | 90,027 | $60,318 | 0.0% | $0.67 | $2.45 | — | COM NEW | 62014P405 |
| — | EQRX INC | 250,000 | $42,500 | 0.0% | $0.17 | $1.06 | — | *W EXP 12/17/202 | 26886C115 |
| — | CAREMAX INC | 60,000 | $23,400 | 0.0% | $0.39 | $4.72 | — | *W EXP 06/08/202 | 14171W111 |
| — | BIOXCEL THERAPEUTICS INC | 439,500 | $10,987 | 0.0% | $0.02 | — | — | Call | 09075P105 |
| SRZNW | SURROZEN INC | 166,666 | $10,000 | 0.0% | $0.06 | $1.14 | — | *W EXP 08/01/203 | 86889P117 |