Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q2 2024 (← Previous) (Next →)
Filing Date: Aug 16, 2024
Total Value: $4.152B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | CEREVEL THERAPEUTICS HLDNG I | 10,794,876 | $441M | 10.6% | $40.89 | $25.62 | — | COM | 15678U128 |
| FOLD | AMICUS THERAPEUTICS INC | 28,057,456 | $278M | 6.7% | $9.92 * | $7.36 | +39.4% | COM | 03152W109 |
| ACLX | ARCELLX INC | 3,889,739 | $215M | 5.2% | $55.19 | $24.76 | +119.6% | COMMON STOCK | 03940C100 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 25,933,142 | $208M | 5.0% | $8.02 * | $11.96 | -10.4% | COM | 462260100 |
| NUVL | NUVALENT INC | 2,549,077 | $193M | 4.7% | $75.86 * | $30.85 | +130.6% | COM | 670703107 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 3,446,579 | $142M | 3.4% | $41.06 * | $34.92 | +14.3% | COM | 76243J105 |
| PCVX | VAXCYTE INC | 1,862,608 | $141M | 3.4% | $75.51 * | $53.61 | +27.0% | COM | 92243G108 |
| SLNO | SOLENO THERAPEUTICS INC | 3,204,976 | $131M | 3.1% | $40.80 * | $6.32 | +570.1% | COM | 834203309 |
| — | INTRA-CELLULAR THERAPIES INC | 1,716,407 | $118M | 2.8% | $68.49 | $69.08 | — | COM | 46116X101 |
| IMTX | IMMATICS N.V | 8,086,159 | $93.96M | 2.3% | $11.62 * | $10.98 | +2.6% | SHS | N44445109 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 649,909 | $89.47M | 2.2% | $137.67 | $120.49 | +13.8% | COM | 64125C109 |
| APGE | APOGEE THERAPEUTICS INC | 2,105,636 | $82.86M | 2.0% | $39.35 * | $24.99 | +94.2% | COM | 03770N101 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 264,600 | $74.13M | 1.8% | $280.16 * | $189.75 | +25.4% | COM | 558868105 |
| AORT | ARTIVION INC | 2,793,703 | $71.66M | 1.7% | $25.65 * | $19.16 | +17.0% | COM | 228903100 |
| SYRE | SPYRE THERAPEUTICS INC | 3,031,018 | $71.26M | 1.7% | $23.51 * | $16.88 | +99.8% | COM NEW | 00773J202 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 1,476,203 | $66.12M | 1.6% | $44.79 * | $27.14 | +70.2% | COM | 22663K107 |
| EOLS | EVOLUS INC | 5,753,798 | $62.43M | 1.5% | $10.85 * | $10.21 | +20.5% | COM | 30052C107 |
| — | SPRINGWORKS THERAPEUTICS INC | 1,652,962 | $62.27M | 1.5% | $37.67 | $38.38 | — | COM | 85205L107 |
| — | CARGO THERAPEUTICS INC | 3,683,004 | $60.47M | 1.5% | $16.42 | $22.72 | — | COM | 14179K101 |
| — | ASTRIA THERAPEUTICS INC | 6,485,420 | $59.02M | 1.4% | $9.10 | $11.36 | — | COM | 04635X102 |
| NTRA | NATERA INC | 530,000 | $57.39M | 1.4% | $108.29 * | $49.41 | +105.6% | COM | 632307104 |
| — | VERRICA PHARMACEUTICALS INC | 7,099,182 | $51.75M | 1.2% | $7.29 | $12.42 | — | COM | 92511W108 |
| BHVN | BIOHAVEN LTD | 1,485,232 | $51.55M | 1.2% | $34.71 * | $25.94 | +52.4% | COM | G1110E107 |
| IMVT | IMMUNOVANT INC | 1,923,786 | $50.79M | 1.2% | $26.40 * | $23.03 | +23.5% | COM | 45258J102 |
| MGTX | MEIRAGTX HLDGS PLC | 11,331,103 | $47.67M | 1.1% | $4.21 * | $11.20 | -55.0% | COM | G59665102 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 1,268,735 | $43.96M | 1.1% | $34.65 * | $25.37 | +15.5% | COM | 74366E102 |
| SLDB | SOLID BIOSCIENCES INC | 6,906,646 | $39.16M | 0.9% | $5.67 * | $7.94 | +12.8% | COM NEW | 83422E204 |
| CELC | CELCUITY INC | 2,362,279 | $38.69M | 0.9% | $16.38 * | $13.53 | +23.7% | COM | 15102K100 |
| MDT | MEDTRONIC PLC | 490,665 | $38.62M | 0.9% | $78.71 | $77.49 | +0.7% | SHS | G5960L103 |
| VKTX | VIKING THERAPEUTICS INC | 721,377 | $38.24M | 0.9% | $53.01 * | $44.50 | +47.3% | COM | 92686J106 |
| — | APPLIED THERAPEUTICS INC | 8,005,000 | $37.38M | 0.9% | $4.67 | $5.04 | — | COM | 03828A101 |
| AXSM | AXSOME THERAPEUTICS INC | 459,111 | $36.96M | 0.9% | $80.50 * | $71.10 | +4.1% | COM | 05464T104 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 3,933,307 | $35.52M | 0.9% | $9.03 | $10.81 | — | SPONSORED ADS | 152309100 |
| TARS | TARSUS PHARMACEUTICALS INC | 1,296,416 | $35.24M | 0.8% | $27.18 * | $28.48 | +18.0% | COM | 87650L103 |
| — | VERONA PHARMA PLC | 2,433,725 | $35.19M | 0.8% | $14.46 | $12.90 | — | SPONSORED ADS | 925050106 |
| — | AKERO THERAPEUTICS INC | 1,499,897 | $35.19M | 0.8% | $23.46 | $36.99 | — | COM | 00973Y108 |
| EWTX | EDGEWISE THERAPEUTICS INC | 1,856,417 | $33.43M | 0.8% | $18.01 * | $13.77 | +26.7% | COM | 28036F105 |
| ACRV | ACRIVON THERAPEUTICS INC | 5,360,858 | $31.09M | 0.7% | $5.80 * | $10.66 | -24.4% | COMMON STOCK | 004890109 |
| PRAX | PRAXIS PRECISION MEDICINES I | 750,230 | $31.03M | 0.7% | $41.36 * | $44.86 | +5.3% | COM NEW | 74006W207 |
| ADMA | ADMA BIOLOGICS INC | 2,771,000 | $30.98M | 0.7% | $11.18 * | $3.92 | +113.9% | COM | 000899104 |
| BBIO | BRIDGEBIO PHARMA INC | 1,215,346 | $30.78M | 0.7% | $25.33 * | $30.14 | -9.3% | COM | 10806X102 |
| ALDX | ALDEYRA THERAPEUTICS INC | 9,275,851 | $30.7M | 0.7% | $3.31 * | $7.81 | -49.8% | COM | 01438T106 |
| NAUT | NAUTILUS BIOTECHNOLOGY INC | 12,594,211 | $29.47M | 0.7% | $2.34 * | $8.54 | -69.4% | COM | 63909J108 |
| CTNM | CONTINEUM THERAPEUTICS INC | 1,566,668 | $27.59M | 0.7% | $17.61 * | $16.10 | 0.0% | CL A | 21217B100 |
| ISRG | INTUITIVE SURGICAL INC | 61,800 | $27.49M | 0.7% | $444.85 * | $334.77 | +19.0% | COM NEW | 46120E602 |
| ARVN | ARVINAS INC | 1,027,749 | $27.36M | 0.7% | $26.62 * | $37.87 | -15.9% | COM | 04335A105 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,246,597 | $26.84M | 0.6% | $21.53 * | $20.82 | +10.3% | COM | 77313F106 |
| IRON | DISC MEDICINE INC | 553,437 | $24.94M | 0.6% | $45.07 * | $39.61 | -14.2% | COM | 254604101 |
| LIVN | LIVANOVA PLC | 444,000 | $24.34M | 0.6% | $54.82 * | $53.60 | +6.3% | SHS | G5509L101 |
| CGON | CG ONCOLOGY INC | 733,695 | $23.16M | 0.6% | $31.57 * | $40.84 | -15.1% | COM | 156944100 |
| XENE | XENON PHARMACEUTICALS INC | 583,256 | $22.74M | 0.5% | $38.99 * | $26.63 | +50.1% | COM | 98420N105 |
| OCUL | OCULAR THERAPEUTIX INC | 3,324,468 | $22.74M | 0.5% | $6.84 * | $7.10 | -13.0% | COM | 67576A100 |
| PEPG | PEPGEN INC | 1,410,438 | $22.51M | 0.5% | $15.96 * | $11.81 | +21.4% | COM | 713317105 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 1,631,828 | $21.23M | 0.5% | $13.01 * | $19.17 | -27.8% | COM | 92790C104 |
| OBIO | ORCHESTRA BIOMED HLDGS INC | 2,545,881 | $20.75M | 0.5% | $8.15 * | $10.64 | -45.6% | COM | 68572M106 |
| — | MERUS N V | 300,000 | $17.75M | 0.4% | $59.17 | $59.17 | — | COM | N5749R100 |
| RAPP | RAPPORT THERAPEUTICS INC | 748,183 | $17.4M | 0.4% | $23.26 | $23.15 | 0.0% | COM | 75383L102 |
| TYRA | TYRA BIOSCIENCES INC | 1,007,367 | $16.11M | 0.4% | $15.99 * | $17.64 | -2.4% | COM | 90240B106 |
| INBX | INHIBRX BIOSCIENCES INC | 1,064,026 | $15.08M | 0.4% | $14.17 * | $15.62 | 0.0% | COM | 45720N103 |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 1,558,500 | $14.49M | 0.3% | $9.30 * | $8.28 | +9.2% | COM | 03969K108 |
| — | ATHIRA PHARMA INC | 5,402,964 | $14.32M | 0.3% | $2.65 | $12.75 | — | COM | 04746L104 |
| ZYME | ZYMEWORKS INC | 1,667,711 | $14.19M | 0.3% | $8.51 * | $7.69 | +15.7% | COM | 98985Y108 |
| CGEM | CULLINAN THERAPEUTICS INC | 749,916 | $13.08M | 0.3% | $17.44 * | $21.29 | 0.0% | COM | 230031106 |
| PRCT | PROCEPT BIOROBOTICS CORP | 210,659 | $12.87M | 0.3% | $61.09 * | $47.60 | +25.0% | COM | 74276L105 |
| INSM | INSMED INC | 180,000 | $12.06M | 0.3% | $67.00 * | $38.78 | 0.0% | COM PAR $.01 | 457669307 |
| BCYC | BICYCLE THERAPEUTICS PLC | 572,000 | $11.58M | 0.3% | $20.24 | $20.24 | — | SPONSORED ADS | 088786108 |
| ICLR | ICON PLC | 31,250 | $9.796M | 0.2% | $313.47 | $313.39 | 0.0% | SHS | G4705A100 |
| TEM | TEMPUS AI INC | 275,000 | $9.625M | 0.2% | $35.00 * | $30.66 | 0.0% | CL A | 88023B103 |
| AVBP | ARRIVENT BIOPHARMA INC | 415,000 | $7.698M | 0.2% | $18.55 * | $20.17 | -11.6% | COM | 04272N102 |
| ENGN | ENGENE HOLDINGS INC | 800,000 | $7.544M | 0.2% | $9.43 * | $12.24 | +4.8% | COM | 29286M105 |
| SPRY | ARS PHARMACEUTICALS INC | 867,319 | $7.381M | 0.2% | $8.51 * | $7.46 | +19.0% | COM | 82835W108 |
| ARGX | ARGENX SE | 15,600 | $6.709M | 0.2% | $430.04 | $430.04 | — | SPONSORED ADR | 04016X101 |
| ALLO | ALLOGENE THERAPEUTICS INC | 2,725,000 | $6.349M | 0.2% | $2.33 * | $2.95 | 0.0% | COM | 019770106 |
| — | VERU INC | 7,063,277 | $5.942M | 0.1% | $0.84 | $0.81 | — | COM | 92536C103 |
| KALV | KALVISTA PHARMACEUTICALS INC | 500,000 | $5.89M | 0.1% | $11.78 | $13.33 | -12.5% | COM | 483497103 |
| RXRX | RECURSION PHARMACEUTICALS IN | 769,230 | $5.769M | 0.1% | $7.50 * | $8.72 | 0.0% | CL A | 75629V104 |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 640,274 | $5.57M | 0.1% | $8.70 * | $11.40 | +22.6% | COM NEW | 30233G209 |
| IMVT | IMMUNOVANT INC | 200,000 | $5.28M | 0.1% | $26.40 * | $23.03 | +23.5% | Call | 45258J102 |
| BBOT | HELIX ACQUISITION CORP II | 500,000 | $5.11M | 0.1% | $10.22 | $10.35 | -0.6% | CL A ORD SHS | G4444H101 |
| MREO | MEREO BIOPHARMA GROUP PLC | 1,253,250 | $4.512M | 0.1% | $3.60 | $3.60 | — | SPON ADS | 589492107 |
| CABA | CABALETTA BIO INC | 585,045 | $4.376M | 0.1% | $7.48 * | $12.38 | -1.0% | COM | 12674W109 |
| DTIL | PRECISION BIOSCIENCES INC | 426,293 | $4.148M | 0.1% | $9.73 * | $12.24 | -3.7% | COM NEW | 74019P207 |
| SKYE | SKYE BIOSCIENCE INC | 500,000 | $4.005M | 0.1% | $8.01 * | $11.84 | 0.0% | COM NEW | 83086J200 |
| TRIB | TRINITY BIOTECH PLC | 1,800,000 | $3.834M | 0.1% | $2.13 | $2.04 | — | SPONS ARD NEW | 896438504 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 35,205 | $3.789M | 0.1% | $107.64 * | $112.42 | -9.1% | COM | 450056106 |
| — | LYRA THERAPEUTICS INC | 12,757,562 | $3.534M | 0.1% | $0.28 | $6.65 | — | COM | 55234L105 |
| — | BIODESIX INC | 2,173,880 | $3.326M | 0.1% | $1.53 | $1.53 | — | COM | 09075X108 |
| — | ENVVENO MEDICAL CORPORATION | 623,315 | $3.272M | 0.1% | $5.25 | $6.59 | — | COM | 29415J106 |
| FHTX | FOGHORN THERAPEUTICS INC | 544,000 | $3.128M | 0.1% | $5.75 * | $5.96 | 0.0% | COM | 344174107 |
| NBTX | NANOBIOTIX | 555,066 | $2.775M | 0.1% | $5.00 | $16.50 | — | SPONSORED ADS | 63009J107 |
| SAVA | CASSAVA SCIENCES INC | 183,000 | $2.26M | 0.1% | $12.35 | — | — | Put | 14817C107 |
| ABSI | ABSCI CORPORATION | 700,000 | $2.156M | 0.1% | $3.08 * | $4.51 | +2.9% | COM | 00091E109 |
| XBI | SPDR SER TR | 22,665 | $2.101M | 0.1% | $92.71 | $92.71 | — | S&P BIOTECH | 78464A870 |
| — | X4 PHARMACEUTICALS INC | 3,545,454 | $2.056M | 0.0% | $0.58 | $0.87 | — | COM | 98420X103 |
| — | FORTE BIOSCIENCES INC | 3,265,359 | $1.753M | 0.0% | $0.54 | $0.66 | — | COM | 34962G109 |
| — | REVANCE THERAPEUTICS INC | 600,000 | $1.542M | 0.0% | $2.57 | $4.92 | — | COM | 761330109 |
| GPCR | STRUCTURE THERAPEUTICS INC | 34,852 | $1.369M | 0.0% | $39.27 | $39.27 | — | SPONSORED ADS | 86366E106 |
| NVAX | NOVAVAX INC | 100,000 | $1.266M | 0.0% | $12.66 | — | — | Put | 670002401 |
| FATE | FATE THERAPEUTICS INC | 345,575 | $1.133M | 0.0% | $3.28 * | $4.38 | 0.0% | COM | 31189P102 |
| KYTX | KYVERNA THERAPEUTICS INC | 150,000 | $1.125M | 0.0% | $7.50 * | $27.84 | -45.1% | COM | 501976104 |
| EGRX | EAGLE PHARMACEUTICALS INC | 173,365 | $971K | 0.0% | $5.60 * | $4.36 | 0.0% | COM | 269796108 |
| — | VBI VACCINES INC CDA | 1,261,710 | $833K | 0.0% | $0.66 | $3.29 | — | COM NEW | 91822J202 |
| TCMD | TACTILE SYS TECHNOLOGY INC | 62,639 | $748K | 0.0% | $11.94 * | $14.84 | -9.3% | COM | 87357P100 |
| SYRS | SYROS PHARMACEUTICALS INC | 116,754 | $602K | 0.0% | $5.16 | $6.91 | -24.0% | COM NEW | 87184Q206 |
| — | SINGULAR GENOMICS SYSTEMS IN | 70,896 | $599K | 0.0% | $8.45 | $8.45 | — | COM NEW | 82933R308 |
| — | CAREMAX INC | 122,643 | $342K | 0.0% | $2.79 | $4.82 | — | CL A NEW | 14171W202 |
| AXGN | AXOGEN INC | 30,421 | $220K | 0.0% | $7.24 * | $9.65 | -29.2% | COM | 05463X106 |
| RVMDW | REVOLUTION MEDICINES INC | 250,000 | $25,525 | 0.0% | $0.10 | $0.33 | — | *W EXP 12/17/202 | 76155X118 |
| SRZNW | SURROZEN INC | 166,666 | $2,767 | 0.0% | $0.02 | $1.14 | — | *W EXP 08/01/203 | 86889P117 |
| — | CAREMAX INC | 60,000 | $846 | 0.0% | $0.01 | $4.72 | — | *W EXP 06/08/202 | 14171W111 |