Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q4 2013 (← Previous) (Next →)
Filing Date: Feb 14, 2014
Total Value: $833M (99.9% shares, 0.1% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | CELGENE CORP | 509,200 | $86.03M | 10.3% | $168.96 | $151.32 | — | COM | 151020104 |
| — | ACELRX PHARMACEUTICALS INC | 6,574,060 | $74.35M | 8.9% | $11.31 | $9.69 | — | COM | 00444T100 |
| SRPT | SAREPTA THERAPEUTICS INC | 3,484,579 | $70.98M | 8.5% | $20.37 * | $34.57 | -14.0% | COM | 803607100 |
| VRTX | VERTEX PHARMACEUTICALS INC | 811,728 | $60.31M | 7.2% | $74.30 * | $73.30 | -5.0% | COM | 92532F100 |
| — | TESARO INC | 1,446,570 | $40.85M | 4.9% | $28.24 | $35.09 | — | COM | 881569107 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 4,183,737 | $39.08M | 4.7% | $9.34 * | $12.28 | -20.6% | COM | 64125C109 |
| — | AEGERION PHARMACEUTICALS INC | 447,785 | $31.77M | 3.8% | $70.96 | $70.96 | — | COM | 00767E102 |
| — | COVIDIEN PLC | 374,826 | $25.53M | 3.1% | $68.10 | $64.41 | — | SHS | G2554F113 |
| EXAS | EXACT SCIENCES CORP | 1,969,903 | $23.03M | 2.8% | $11.69 | $11.03 | +4.0% | COM | 30063P105 |
| — | MANNKIND CORP | 3,795,000 | $19.77M | 2.4% | $5.21 | $5.25 | — | COM | 56400P201 |
| MGNX | MACROGENICS INC | 717,705 | $19.69M | 2.4% | $27.43 * | $26.16 | 0.0% | COM | 556099109 |
| — | WALGREEN CO | 322,000 | $18.5M | 2.2% | $57.44 | $55.32 | — | COM | 931422109 |
| ABBV | ABBVIE INC | 350,000 | $18.48M | 2.2% | $52.81 * | $30.39 | 0.0% | COM | 00287Y109 |
| — | DYAX CORP | 2,332,674 | $17.57M | 2.1% | $7.53 | $7.53 | — | COM | 26746E103 |
| — | NEPTUNE TECHNOLOGIES BIORESO | 5,900,444 | $17.11M | 2.1% | $2.90 | $3.22 | — | COM | 64077P108 |
| — | MYLAN INC | 392,500 | $17.04M | 2.0% | $43.40 | $38.17 | — | COM | 628530107 |
| XNCR | XENCOR INC | 1,568,672 | $14.34M | 1.7% | $9.14 * | $8.58 | 0.0% | COM | 98401F105 |
| INCY | INCYTE CORP | 268,800 | $13.61M | 1.6% | $50.63 * | $43.51 | 0.0% | COM | 45337C102 |
| SRPT | Sarepta Therapeutics Inc | 650,000 | $13.24M | 1.6% | $20.37 * | $34.57 | -14.0% | Put | 803607100 |
| BIIB | BIOGEN IDEC INC | 40,000 | $11.19M | 1.3% | $279.75 * | $258.65 | 0.0% | COM | 09062X103 |
| — | CIGNA CORPORATION | 125,000 | $10.94M | 1.3% | $87.48 | $76.85 | — | COM | 125509109 |
| — | SPECTRANETICS CORP | 346,254 | $8.656M | 1.0% | $25.00 | $22.19 | — | COM | 84760C107 |
| — | RELYPSA INC | 341,200 | $8.53M | 1.0% | $25.00 | $25.00 | — | COM | 759531106 |
| — | ANACOR PHARMACEUTICALS INC | 487,542 | $8.181M | 1.0% | $16.78 | $16.78 | — | COM | 32420101 |
| — | HEALTH NET INC | 272,775 | $8.094M | 1.0% | $29.67 | $31.70 | — | COM | 42222G108 |
| — | HEARTWARE INTL INC | 84,900 | $7.977M | 1.0% | $93.96 | $92.74 | — | COM | 422368100 |
| — | CHELSEA THERAPEUTICS INTL LT | 1,701,639 | $7.538M | 0.9% | $4.43 | $2.30 | — | COM | 163428105 |
| — | RETROPHIN INC | 1,052,692 | $7.368M | 0.9% | $7.00 | $7.00 | — | COM | 761299106 |
| — | CELL THERAPEUTICS INC | 3,715,000 | $7.133M | 0.9% | $1.92 | $1.62 | — | COM NPV NEW 2012 | 150934883 |
| — | GENTIUM S P A | 120,000 | $6.852M | 0.8% | $57.10 | $57.10 | — | SPONSORED ADR | 37250B104 |
| CVS | CVS CAREMARK CORPORATION | 89,330 | $6.393M | 0.8% | $71.57 * | $46.22 | +0.2% | COM | 126650100 |
| — | ZELTIQ AESTHETICS INC | 305,593 | $5.779M | 0.7% | $18.91 | $18.47 | — | COM | 98933Q108 |
| ARNI | ARNO THERAPEUTICS | 2,034,721 | $5.697M | 0.7% | $2.80 * | $3.14 | 0.0% | COM | 042564203 |
| — | TARO PHARMACEUTICAL INDS LTD | 56,602 | $5.598M | 0.7% | $98.90 | $98.90 | — | SHS | M8737E108 |
| — | AERIE PHARMACEUTICALS INC | 300,000 | $5.388M | 0.6% | $17.96 | $17.96 | — | COM | 00771V108 |
| — | ACASTI PHARMA INC | 4,389,685 | $5.236M | 0.6% | $1.19 | $1.23 | — | CL A SHS | 00430K105 |
| — | ENDOCYTE INC | 671,300 | $5.234M | 0.6% | $7.80 | $11.23 | — | COM | 29269A102 |
| — | CAPITAL SR LIVING CORP | 208,753 | $5.008M | 0.6% | $23.99 | $23.90 | — | COM | 140475104 |
| INFIQ | INFINITY PHARMACEUTICALS INC | 350,000 | $4.834M | 0.6% | $13.81 * | $20.70 | -31.8% | COM | 45665G303 |
| — | ATHERSYS INC | 1,700,887 | $4.252M | 0.5% | $2.50 | $1.66 | — | COM | 04744L106 |
| — | ALLIQUA | 557,491 | $4.041M | 0.5% | $7.25 | $7.25 | — | COM | 019621200 |
| GILD | GILEAD SCIENCES INC | 50,000 | $3.758M | 0.5% | $75.16 * | $36.68 | +31.9% | COM | 375558103 |
| — | TANDEM DIABETES CARE INC | 125,600 | $3.236M | 0.4% | $25.76 | $25.76 | — | COM | 875372104 |
| — | VERASTEM INC | 220,000 | $2.517M | 0.3% | $11.44 | $12.45 | — | COM | 92337C104 |
| — | OPHTHOTECH CORP | 75,000 | $2.426M | 0.3% | $32.35 | $32.35 | — | COM | 683745103 |
| — | MGC DIAGNOSTICS CORP | 179,619 | $2.274M | 0.3% | $12.66 | $8.48 | — | COM | 552768103 |
| — | CHIMERIX INC | 150,000 | $2.262M | 0.3% | $15.08 | $15.08 | — | COM | 16934W106 |
| RGEN | REPLIGEN CORP | 165,000 | $2.251M | 0.3% | $13.64 | — | — | Put | 759916109 |
| — | ZOGENIX INC | 650,000 | $2.236M | 0.3% | $3.44 | $3.44 | — | COM | 98978L105 |
| — | FIVE PRIME THERAPEUTICS INC | 132,500 | $2.225M | 0.3% | $16.79 | $16.79 | — | COM | 33830X104 |
| — | ENDOCYTE INC | 200,000 | $2.138M | 0.3% | $10.69 | $11.23 | — | Put | 29269A102 |
| — | ENDOCYTE INC | 200,000 | $2.138M | 0.3% | $10.69 | $11.23 | — | Call | 29269A102 |
| — | AUXILIUM PHARMACEUTICALS INC | 100,000 | $2.074M | 0.2% | $20.74 | $20.74 | — | COM | 05334D107 |
| — | CHAMPION ONCOLOGY | 1,625,744 | $1.95M | 0.2% | $1.20 | $1.20 | — | COM | 15870P109 |
| ZBH | ZIMMER HLDGS INC | 20,000 | $1.864M | 0.2% | $93.20 * | $78.29 | 0.0% | COM | 98956P102 |
| — | CLOVIS ONCOLOGY INC | 30,585 | $1.843M | 0.2% | $60.26 | $65.27 | — | COM | 189464100 |
| — | IDENIX PHARMACEUTICALS INC | 300,000 | $1.794M | 0.2% | $5.98 | — | — | Call | 45166R204 |
| — | NEOSTEM INC | 229,593 | $1.566M | 0.2% | $6.82 | $8.55 | — | COM PAR $.001 | 640650404 |
| BCRX | BIOCRYST PHARMACEUTICALS | 197,500 | $1.501M | 0.2% | $7.60 * | $5.12 | +23.8% | COM | 09058V103 |
| — | SANTARUS INC | 45,400 | $1.451M | 0.2% | $31.96 | $21.05 | — | COM | 802817304 |
| — | SHIRE PLC | 10,000 | $1.413M | 0.2% | $141.30 | $141.30 | — | SPONSORED ADR | 82481R106 |
| — | ANTHERA PHARMACEUTICALS INC | 431,456 | $1.325M | 0.2% | $3.07 | $4.02 | — | COM NEW | 03674U201 |
| — | REPROS THERAPEUTICS INC | 71,879 | $1.315M | 0.2% | $18.29 | $25.78 | — | COM NEW | 76028H209 |
| DXCM | DEXCOM INC | 30,000 | $1.062M | 0.1% | $35.40 * | $6.33 | +24.9% | COM | 252131107 |
| — | TRANSGENOMIC INC | 2,207,500 | $1.004M | 0.1% | $0.45 | $0.38 | — | COM | 89365k206 |
| — | CURIS INC | 350,000 | $987K | 0.1% | $2.82 | $2.82 | — | COM | 231269101 |
| — | VIVUS INC | 100,000 | $908K | 0.1% | $9.08 | — | — | Put | 928551100 |
| — | ONCOTHYREON INC | 500,000 | $880K | 0.1% | $1.76 | $2.05 | — | COM | 682324108 |
| MDXG | MIMEDX GROUP INC | 100,000 | $874K | 0.1% | $8.74 * | $6.12 | 0.0% | COM | 602496101 |
| — | UROPLASTY INC | 313,989 | $857K | 0.1% | $2.73 | $2.11 | — | COM NEW | 917277204 |
| UTHR | UNITED THERAPEUTICS CORP DEL | 7,000 | $792K | 0.1% | $113.14 * | $90.18 | 0.0% | COM | 91307C102 |
| — | OREXIGEN THERAPEUTICS INC | 750,000 | $732K | 0.1% | $0.98 | $0.98 | — | NOTE 2.750%12/0 | 686164AA2 |
| — | SURGICAL CARE AFFILIATES INC | 20,000 | $697K | 0.1% | $34.85 | $34.85 | — | COM | 86881L106 |
| — | NANOSPHERE INC | 295,000 | $676K | 0.1% | $2.29 | $2.00 | — | COM | 63009F105 |
| HOLX | HOLOGIC INC | 25,000 | $559K | 0.1% | $22.36 | — | — | Call | 436440101 |
| — | BLUEBIRD BIO INC | 20,000 | $420K | 0.1% | $21.00 | $21.00 | — | COM | 09609G100 |
| — | NEWCASTLE INVT CORP | 70,000 | $402K | 0.0% | $5.74 | $5.74 | — | COM | 65105M108 |
| — | MEDGENICS INC | 61,263 | $367K | 0.0% | $5.99 | $3.80 | — | COM NEW | 58436Q203 |
| — | ATHENAHEALTH INC | 2,500 | $336K | 0.0% | $134.40 | — | — | Call | 04685W103 |
| — | STEMCELLS INC | 271,600 | $334K | 0.0% | $1.23 | $1.59 | — | COM NEW | 85857R204 |
| — | XENOPORT INC | 50,000 | $288K | 0.0% | $5.76 | $5.68 | — | COM | 98411C100 |
| — | CUTERA INC | 22,400 | $228K | 0.0% | $10.18 | $9.41 | — | COM | 232109108 |
| — | LANNET INC | 6,744 | $223K | 0.0% | $33.07 | $33.07 | — | COM | 516012101 |
| ILMN | ILLUMINA INC | 2,000 | $221K | 0.0% | $110.50 * | $91.59 | 0.0% | COM | 452327109 |
| — | INSYS THERAPEUTICS INC NEW | 5,722 | $221K | 0.0% | $38.62 | $38.62 | — | COM NEW | 45824V209 |
| — | MEDIDATA SOLUTIONS INC | 3,642 | $220K | 0.0% | $60.41 | $60.41 | — | COM | 58471A105 |
| MYGN | MYRIAD GENETICS INC | 10,000 | $210K | 0.0% | $21.00 | — | — | Put | 62855J104 |
| — | NAVIDEA BIOPHARMACEUTICALS I | 100,000 | $207K | 0.0% | $2.07 | — | — | Put | 63937X103 |
| — | TORNIER N V | 10,000 | $188K | 0.0% | $18.80 | $18.80 | — | SHS | N87237108 |
| — | PAIN THERAPEUTICS INC | 35,506 | $172K | 0.0% | $4.84 | $4.84 | — | COM | 69562K100 |
| CNC | CENTENE CORP DEL | 2,610 | $154K | 0.0% | $59.00 * | $14.45 | +3.5% | COM | 15135B101 |
| — | ASTRAZENECA PLC | 2,558 | $152K | 0.0% | $59.42 | $59.42 | — | SPONSORED ADR | 46353108 |
| — | HILL ROM HLDGS INC | 3,687 | $152K | 0.0% | $41.23 | $41.23 | — | COM | 431475102 |
| DVA | DAVITA HEALTHCARE PARTNERS I | 2,382 | $151K | 0.0% | $63.39 * | $57.33 | +2.4% | COM | 23918K108 |
| — | IMPAX LABORATORIES INC | 5,962 | $150K | 0.0% | $25.16 | $25.16 | — | COM | 45256B101 |
| — | OMNICARE INC | 2,492 | $150K | 0.0% | $60.19 | $54.03 | — | COM | 681904108 |
| — | ALERE INC | 4,127 | $149K | 0.0% | $36.10 | $29.49 | — | COM | 01449J105 |
| — | ANALOGIC CORP | 1,644 | $146K | 0.0% | $88.81 | $88.81 | — | COM PAR $0.05 | 32657207 |
| — | EXPRESS SCRIPTS HLDG CO | 2,080 | $146K | 0.0% | $70.19 | $70.19 | — | COM | 30219G108 |
| LAB | FLUIDIGM CORP DEL | 2,030 | $78,000 | 0.0% | $38.42 * | $29.45 | 0.0% | COM | 34385P108 |
| — | ENDO HEALTH SOLUTIONS INC | 1,138 | $77,000 | 0.0% | $67.66 | $67.66 | — | COM | 29264F205 |
| PBYI | PUMA BIOTECHNOLOGY INC | 735 | $76,000 | 0.0% | $103.40 * | $58.69 | 0.0% | COM | 74587V107 |
| — | RITE AID CORP | 14,924 | $76,000 | 0.0% | $5.09 | $5.09 | — | COM | 767754104 |
| — | AFFYMETRIX INC | 8,538 | $73,000 | 0.0% | $8.55 | $8.55 | — | COM | 00826T108 |
| GERN | GERON CORP | 4,684 | $22,000 | 0.0% | $4.70 * | $4.29 | 0.0% | COM | 374163103 |
| AXGN | AXOGEN INC | 4,500 | $20,000 | 0.0% | $4.44 * | $3.83 | +6.1% | COM | 05463X106 |
| — | IMMUNOMEDICS INC | 2,853 | $13,000 | 0.0% | $4.56 | $5.44 | — | COM | 452907108 |
| — | COMBIMATRIX CORPORATION | 5,000 | $3,000 | 0.0% | $0.60 | $0.20 | — | *W EXP 05/01/201 | 20009T121 |
| — | STEMLINE THERAPEUTICS INC | 38 | $1,000 | 0.0% | $26.32 | $23.84 | — | COM | 85858C107 |