Location: New York, NY
CIK: 0001224962 · Show all filings
Period: Q1 2014 (← Previous) (Next →)
Filing Date: May 15, 2014
Total Value: $952M (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | ACELRX PHARMACEUTICALS INC | 6,574,060 | $78.95M | 8.3% | $9.69 | — | COM | 00444T100 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 4,619,367 | $74.37M | 7.8% | $12.74 | +34.3% | COM | 64125C109 |
| SRPT | SAREPTA THERAPEUTICS INC | 2,878,979 | $69.18M | 7.3% | $34.57 | -26.2% | COM | 803607100 |
| VRTX | VERTEX PHARMACEUTICALS INC | 581,728 | $41.14M | 4.3% | $73.30 | +8.1% | COM | 92532F100 |
| — | TESARO INC | 1,230,070 | $36.26M | 3.8% | $35.09 | — | COM | 881569107 |
| — | CELGENE CORP | 206,200 | $28.79M | 3.0% | $151.32 | — | COM | 151020104 |
| — | LION BIOTECHNOLOGIES | 3,000,000 | $28.32M | 3.0% | $9.44 | — | COM | 53619R102 |
| EXAS | EXACT SCIENCES CORP | 1,825,150 | $25.86M | 2.7% | $11.03 | +22.5% | COM | 30063P105 |
| HRTX | HERON THERAPEUTICS INC | 1,762,426 | $24.52M | 2.6% | $12.60 | 0.0% | COM | 427746102 |
| — | DYAX CORP | 2,562,674 | $23.01M | 2.4% | $7.66 | — | COM | 26746E103 |
| — | RETROPHIN INC | 1,044,292 | $22.14M | 2.3% | $7.00 | — | COM | 761299106 |
| VRTX | VERTEX PHARMACEUTICALS INC | 300,000 | $21.22M | 2.2% | $73.30 | +8.1% | Put | 92532F100 |
| — | WALGREEN CO | 304,419 | $20.1M | 2.1% | $55.32 | — | COM | 931422109 |
| — | COVIDIEN PLC | 262,900 | $19.36M | 2.0% | $64.41 | — | SHS | G2554F113 |
| PTCT | PTC THERAPEUTICS | 671,736 | $17.56M | 1.8% | $26.87 | 0.0% | COM | 69366J200 |
| XNCR | XENCOR INC | 1,488,672 | $17.46M | 1.8% | $8.58 | +22.5% | COM | 98401F105 |
| — | NEPTUNE TECHNOLOGIES BIORESO | 6,700,444 | $16.55M | 1.7% | $3.13 | — | COM | 64077P108 |
| ACAD | ACADIA PHARMACEUTICALS INC | 666,000 | $16.2M | 1.7% | $25.30 | 0.0% | COM | 004225108 |
| — | VERSARTIS INC | 501,266 | $15.06M | 1.6% | $30.05 | — | COM | 92529L102 |
| SGMO | SANGAMO BIOSCIENCES INC | 800,000 | $14.46M | 1.5% | $19.28 | 0.0% | COM | 800677106 |
| PRTA | PROTHENA CORP PLC | 350,000 | $13.41M | 1.4% | $32.24 | 0.0% | SHS | G72800108 |
| — | ANACOR PHARMACEUTICALS INC | 647,015 | $12.95M | 1.4% | $20.01 | — | COM | 032420101 |
| EXAS | EXACT SCIENCES CORP | 900,000 | $12.75M | 1.3% | $11.03 | +22.5% | Put | 30063P105 |
| MGNX | MACROGENICS INC | 448,945 | $12.49M | 1.3% | $26.16 | +35.0% | COM | 556099109 |
| — | CLOVIS ONCOLOGY INC | 172,217 | $11.93M | 1.3% | $68.56 | — | COM | 189464100 |
| — | ZELTIQ AESTHETICS INC | 586,013 | $11.5M | 1.2% | $19.02 | — | COM | 98933Q108 |
| — | MYLAN INC | 232,500 | $11.35M | 1.2% | $38.17 | — | COM | 628530107 |
| — | TARO PHARMACEUTICAL INDS LTD | 97,011 | $10.77M | 1.1% | $103.94 | — | SHS | M8737E108 |
| — | FLAMEL TECHNOLOGIES SA | 800,000 | $10.72M | 1.1% | $13.40 | — | SPONSORED ADR | 338488109 |
| — | ENDOCYTE INC | 435,000 | $10.36M | 1.1% | $11.23 | — | COM | 29269A102 |
| — | SPECTRANETICS CORP | 332,554 | $10.08M | 1.1% | $22.19 | — | COM | 84760C107 |
| INCY | INCYTE CORP | 183,800 | $9.837M | 1.0% | $43.51 | +42.7% | COM | 45337C102 |
| — | OPHTHOTECH CORP | 250,000 | $8.935M | 0.9% | $34.72 | — | COM | 683745103 |
| — | INTERMUNE INC | 260,000 | $8.702M | 0.9% | $33.47 | — | COM | 45884X103 |
| SRPT | Sarepta Therapeutics Inc | 350,000 | $8.413M | 0.9% | $34.57 | -26.2% | Call | 803607100 |
| HCA | HCA HOLDINGS INC | 150,000 | $7.875M | 0.8% | $46.26 | 0.0% | COM | 40412C101 |
| — | CHELSEA THERAPEUTICS INTL LT | 1,301,639 | $7.185M | 0.8% | $2.30 | — | COM | 163428105 |
| — | DERMA SCIENCES INC | 532,800 | $6.756M | 0.7% | $12.68 | — | COM PAR .01 | 249827502 |
| CYTK | CYTOKINETICS INC | 700,000 | $6.65M | 0.7% | — | — | Call | 23282W605 |
| INSM | INSMED INC | 340,000 | $6.474M | 0.7% | $19.00 | 0.0% | COM PAR .01 | 457669307 |
| — | ALLIQUA | 784,594 | $6.472M | 0.7% | $7.54 | — | COM | 019621200 |
| — | TREVENA INC | 770,000 | $6.052M | 0.6% | $7.86 | — | COM | 89532E109 |
| — | RELYPSA INC | 181,200 | $5.402M | 0.6% | $25.00 | — | COM | 759531106 |
| — | CAPITAL SR LIVING CORP | 202,500 | $5.263M | 0.6% | $23.90 | — | COM | 140475104 |
| — | ARROWHEAD RESH CORP | 317,300 | $5.21M | 0.5% | $16.42 | — | COM NEW | 042797209 |
| — | ENZYMOTEC LTD | 214,219 | $4.717M | 0.5% | $22.02 | — | SHS | M4059L101 |
| — | KERYX BIOPHARMACEUTICALS INC | 275,000 | $4.686M | 0.5% | $17.04 | — | COM | 492515101 |
| GMED | GLOBUS MED INC | 170,000 | $4.52M | 0.5% | $23.76 | 0.0% | CL A SHRS | 379577208 |
| ARNI | ARNO THERAPEUTICS | 2,034,721 | $4.517M | 0.5% | $3.14 | -23.6% | COM | 042564203 |
| — | AERIE PHARMACEUTICALS INC | 211,518 | $4.482M | 0.5% | $17.96 | — | COM | 00771V108 |
| — | SHIRE PLC | 30,000 | $4.456M | 0.5% | $146.12 | — | SPONSORED ADR | 82481R106 |
| GILD | GILEAD SCIENCES INC | 50,000 | $3.543M | 0.4% | $36.68 | +48.6% | COM | 375558103 |
| ABBV | ABBVIE INC | 67,000 | $3.444M | 0.4% | $30.39 | +3.6% | COM | 00287Y109 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 50,000 | $3.357M | 0.4% | $77.42 | 0.0% | COM | 02043Q107 |
| — | INTERMUNE INC | 100,000 | $3.347M | 0.4% | $33.47 | — | Call | 45884X103 |
| — | ACASTI PHARMA INC | 2,869,447 | $3.299M | 0.3% | $1.23 | — | CL A SHRS | 00430K105 |
| — | CHIMERIX INC | 140,000 | $3.199M | 0.3% | $15.08 | — | COM | 16934W106 |
| — | FIVE PRIME THERAPEUTICS INC | 150,000 | $2.949M | 0.3% | $17.13 | — | COM | 33830X104 |
| — | BIOTA PHARMACEUTIALS INC | 415,000 | $2.536M | 0.3% | $6.11 | — | COM | 090694100 |
| — | VERASTEM INC | 220,000 | $2.391M | 0.3% | $12.45 | — | COM | 92337C104 |
| — | TANDEM DIABETES CARE INC | 105,900 | $2.339M | 0.2% | $25.76 | — | COM | 875372104 |
| — | MGC DIAGNOSTICS CORP | 206,957 | $2.31M | 0.2% | $8.83 | — | COM | 552768103 |
| — | ATHERSYS INC | 701,582 | $2.273M | 0.2% | $1.66 | — | COM | 04744L106 |
| — | GENVEC INC | 820,000 | $2.173M | 0.2% | $2.65 | — | COM NEW | 37246C307 |
| — | TEKMIRA PHARMACEUTICALS CORP | 100,000 | $2.149M | 0.2% | — | — | Put | 87911B209 |
| — | MEDIVATION INC | 31,900 | $2.053M | 0.2% | $64.36 | — | COM | 58501N101 |
| FOLD | AMICUS THERAPEUTICS INC | 966,300 | $2M | 0.2% | $2.50 | 0.0% | COM | 03152W109 |
| ATRC | ATRICURE INC | 100,000 | $1.881M | 0.2% | $20.49 | 0.0% | COM | 04963C209 |
| — | UROPLASTY INC | 517,791 | $1.88M | 0.2% | $2.71 | — | COM NEW | 917277204 |
| — | OXIGENE INC | 500,000 | $1.865M | 0.2% | $3.73 | — | COM PAR .001 | 691828404 |
| — | QUESTCOR PHARMACEUTICALS | 28,600 | $1.857M | 0.2% | $64.93 | — | COM | 74835Y101 |
| — | IDENIX PHARMACEUTICALS INC | 300,000 | $1.809M | 0.2% | — | — | Call | 45166R204 |
| CGEN | COMPUGEN LTD | 170,000 | $1.787M | 0.2% | $11.01 | 0.0% | ORD | M25722105 |
| — | AQUINOX PHARMACEUTICALS INC | 130,000 | $1.655M | 0.2% | $12.73 | — | COM | 03842B101 |
| — | ONCOTHYREON INC | 543,000 | $1.624M | 0.2% | $2.12 | — | COM | 682324108 |
| — | CHAMPIONS ONCOLOGY | 1,625,299 | $1.609M | 0.2% | $1.20 | — | COM | 15870P109 |
| — | BIODELIVERY SCIENCES INTL IN | 190,000 | $1.604M | 0.2% | $8.44 | — | COM | 09060J106 |
| — | ANTHERA PHARMACEUTICALS INC | 478,456 | $1.603M | 0.2% | $3.95 | — | COM NEW | 03674U201 |
| — | ICAD INC | 175,000 | $1.603M | 0.2% | $9.16 | — | COM NEW | 44934S206 |
| — | SYNERON MEDICAL LTD | 127,500 | $1.587M | 0.2% | $12.45 | — | ORD | M87245102 |
| — | ENZO BIOCHEM INC | 380,000 | $1.581M | 0.2% | $4.16 | — | COM | 294100102 |
| — | RECEPTOS INC | 35,000 | $1.468M | 0.2% | $41.94 | — | COM | 756207106 |
| — | NEWLINK GENETICS CORP | 50,000 | $1.42M | 0.1% | — | — | Call | 651511107 |
| EXEL | EXELIXIS INC | 400,000 | $1.416M | 0.1% | — | — | Call | 30161Q104 |
| ANIP | ANI PHARMACEUTICALS INC | 45,000 | $1.411M | 0.1% | $26.54 | 0.0% | COM | 00182C103 |
| — | DURECT CORP | 907,064 | $1.206M | 0.1% | $1.33 | — | COM | 266605104 |
| — | EPIZYME INC | 52,602 | $1.198M | 0.1% | $22.77 | — | COM | 29428V104 |
| — | ACHAOGEN INC | 60,000 | $928K | 0.1% | $15.47 | — | COM | 004449104 |
| — | GALMED PHARMACEUTICALS LTD | 75,000 | $860K | 0.1% | $11.47 | — | SHS | M47238106 |
| — | TRANSGENOMIC INC | 183,957 | $842K | 0.1% | $4.58 | — | COM | 89365K305 |
| — | AGENUS INC | 200,000 | $634K | 0.1% | $3.17 | — | COM NEW | 00847G705 |
| — | VIVUS INC | 100,000 | $594K | 0.1% | — | — | Put | 928551100 |
| RGEN | REPLIGEN CORP | 45,000 | $579K | 0.1% | — | — | Put | 759916109 |
| — | BLUEBIRD BIO INC | 20,000 | $455K | 0.0% | $21.00 | — | COM | 09609G100 |
| — | MEDGENICS INC | 61,263 | $428K | 0.0% | $3.80 | — | COM NEW | 58436Q203 |
| — | BIOLINERX LTD | 179,041 | $399K | 0.0% | $2.23 | — | SPONSORED ADR | 09071M106 |
| ILMN | ILLUMINA INC | 2,500 | $372K | 0.0% | $102.66 | +43.1% | COM | 452327109 |
| — | STEMCELLS INC | 271,600 | $364K | 0.0% | $1.59 | — | COM NEW | 85857R204 |
| — | WRIGHT MED GROUP INC | 10,000 | $311K | 0.0% | $31.10 | — | COM | 98235T107 |
| — | XENOPORT INC | 50,000 | $258K | 0.0% | $5.68 | — | COM | 98411C100 |
| — | INSYS THERAPEUTICS INC NEW | 6,153 | $255K | 0.0% | $38.82 | — | COM NEW | 45824V209 |
| — | LANNET INC | 6,744 | $241K | 0.0% | $33.07 | — | COM | 516012101 |
| — | SURGICAL CARE AFFILIATES INC | 7,472 | $230K | 0.0% | $34.85 | — | COM | 86881L106 |
| — | ACTAVIS PLC | 945 | $195K | 0.0% | $206.35 | — | SHS | G0083B108 |
| — | RIGEL PHARMACEUTICALS INC | 50,000 | $194K | 0.0% | $3.88 | — | COM NEW | 766559603 |
| — | PAIN THERAPEUTICS | 35,506 | $194K | 0.0% | $4.84 | — | COM | 69562K100 |
| — | CASTLIGHT HEALTH INC | 8,500 | $180K | 0.0% | $21.18 | — | COM | 14862Q100 |
| — | HEALTH NET INC | 5,275 | $179K | 0.0% | $31.70 | — | COM | 42222G108 |
| DVA | DAVITA HEALTHCARE PARTNERS I | 2,382 | $164K | 0.0% | $57.33 | +15.9% | COM | 23918K108 |
| — | VOCERA COMMUNICATIONS INC | 10,000 | $163K | 0.0% | $16.30 | — | COM | 92857F107 |
| CNC | CENTENE CORP DEL | 2,610 | $162K | 0.0% | $14.45 | +7.1% | COM | 15135B101 |
| — | IMPAX LABORATORIES INC | 5,962 | $158K | 0.0% | $25.16 | — | COM | 45256B101 |
| — | MEDIDATA SOLUTIONS INC | 2,802 | $152K | 0.0% | $60.41 | — | COM | 58471A105 |
| HUM | HUMANA INC | 1,250 | $141K | 0.0% | $94.71 | 0.0% | COM | 444859102 |
| PCRX | PACIRA PHARMACEUTICALS | 2,000 | $139K | 0.0% | $68.02 | 0.0% | COM | 695127100 |
| — | HORIZON PHARMA INC | 9,120 | $138K | 0.0% | $15.13 | — | COM | 44047T109 |
| LAB | FLUIDIGM CORP DEL | 3,070 | $135K | 0.0% | $34.38 | +28.0% | COM | 34385P108 |
| — | ABIOMED INC | 5,000 | $130K | 0.0% | $26.00 | — | COM | 003654100 |
| — | ALERE INC | 3,700 | $127K | 0.0% | $29.49 | — | COM | 01449J105 |
| — | CIGNA CORPORATION | 1,269 | $106K | 0.0% | $76.85 | — | COM | 125509109 |
| — | OMNICARE INC | 1,732 | $103K | 0.0% | $54.03 | — | COM | 681904108 |
| — | RITE AID CORP | 14,924 | $94,000 | 0.0% | $5.09 | — | COM | 767754104 |
| — | ENDO INTL PLC | 1,138 | $78,000 | 0.0% | $68.54 | — | SHS | G30401106 |
| PBYI | PUMA BIOTECHNOLOGY | 735 | $76,000 | 0.0% | $58.69 | +100.3% | COM | 74587V107 |
| — | THERAPEUTICSMD INC | 7,000 | $44,000 | 0.0% | $6.29 | — | COM | 88338N107 |
| — | COMBIMATRIX CORPORATION | 5,000 | $9,000 | 0.0% | $0.20 | — | W EXP 5-1-2014 | 20009T121 |
| — | STEMLINE THERAPEUTICS INC | 38 | $1,000 | 0.0% | $23.84 | — | COM | 85858C107 |