5AM Venture Management, LLC Long-Term Concentrated

Location: San Francisco, CA

CIK: 0001799883 · Show all filings

Period: Q1 2023 (← Previous) (Next →)

Filing Date: May 15, 2023

Total Value: $391M (100.0% shares, 0.0% debt)

Holdings (24)

ELVN ENLIVEN THERAPEUTICS INC 32.5%

Value $127M Shares 5,798,475 Est. Cost $20.34 Unrealized 0.0%

TRDA ENTRADA THERAPEUTICS INC 16.3%

Value $63.92M Shares 4,408,379 Est. Cost $17.12 Unrealized —

— VOR BIOPHARMA INC 8.8%

Value $34.23M Shares 6,361,723 Est. Cost $43.10 Unrealized —

— RALLYBIO CORP 5.3%

Value $20.73M Shares 3,630,724 Est. Cost $17.58 Unrealized —

CRNX CRINETICS PHARMACEUTICALS IN 3.5%

Value $13.85M Shares 862,286 Est. Cost $19.04 Unrealized -2.8%

IRON DISC MEDICINE INC 3.2%

Value $12.47M Shares 588,442 Est. Cost $49.79 Unrealized -55.3%

IDYA IDEAYA BIOSCIENCES INC 3.0%

Value $11.92M Shares 868,520 Est. Cost $7.13 Unrealized +133.5%

— SCPHARMACEUTICALS INC 2.8%

Value $10.89M Shares 1,200,647 Est. Cost $5.92 Unrealized —

— FIBROGEN INC 2.8%

Value $10.81M Shares 579,434 Est. Cost $17.63 Unrealized —

RNAM AVIDITY BIOSCIENCES INC 2.6%

Value $10.22M Shares 665,555 Est. Cost $18.92 Unrealized +16.3%

ARVN ARVINAS INC 2.2%

Value $8.742M Shares 320,000 Est. Cost $29.28 Unrealized +7.9%

COGT COGENT BIOSCIENCES INC 2.2%

Value $8.529M Shares 790,440 Est. Cost $6.91 Unrealized +85.0%

ANAB ANAPTYSBIO INC 2.0%

Value $7.784M Shares 357,733 Est. Cost $28.24 Unrealized -13.9%

VRDN VIRIDIAN THERAPEUTICS INC 1.8%

Value $7.123M Shares 280,000 Est. Cost $17.98 Unrealized +78.4%

— IVERIC BIO INC 1.8%

Value $6.925M Shares 284,626 Est. Cost $16.46 Unrealized —

VKTX VIKING THERAPEUTICS INC 1.5%

Value $5.827M Shares 350,000 Est. Cost $10.33 Unrealized 0.0%

— SPRUCE BIOSCIENCES INC 1.3%

Value $5.224M Shares 2,364,000 Est. Cost $2.21 Unrealized —

— MERSANA THERAPEUTICS INC 1.2%

Value $4.87M Shares 1,185,000 Est. Cost $4.11 Unrealized —

PHVS PHARVARIS N V 1.2%

Value $4.733M Shares 587,600 Est. Cost $18.63 Unrealized -52.8%

— HOMOLOGY MEDICINES INC 1.2%

Value $4.672M Shares 4,535,919 Est. Cost $20.70 Unrealized —

— PEAR THERAPEUTICS INC 1.1%

Value $4.27M Shares 16,744,113 Est. Cost $6.20 Unrealized —

— IMPEL PHARMACEUTICALS INC 1.0%

Value $4.039M Shares 2,884,791 Est. Cost $8.85 Unrealized —

— CIDARA THERAPEUTICS INC 0.4%

Value $1.441M Shares 1,134,511 Est. Cost $3.84 Unrealized —

MLTX MOONLAKE IMMUNOTHERAPEUTICS 0.2%

Value $831K Shares 38,856 Est. Cost $16.81 Unrealized 0.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ELVN	ENLIVEN THERAPEUTICS INC	5,798,475	$127M	32.5%	$20.34	0.0%	COM	29337E102
TRDA	ENTRADA THERAPEUTICS INC	4,408,379	$63.92M	16.3%	$17.12	—	COM	29384C108
—	VOR BIOPHARMA INC	6,361,723	$34.23M	8.8%	$43.10	—	COM	929033108
—	RALLYBIO CORP	3,630,724	$20.73M	5.3%	$17.58	—	COM	75120L100
CRNX	CRINETICS PHARMACEUTICALS IN	862,286	$13.85M	3.5%	$19.04	-2.8%	COM	22663K107
IRON	DISC MEDICINE INC	588,442	$12.47M	3.2%	$49.79	-55.3%	COM	254604101
IDYA	IDEAYA BIOSCIENCES INC	868,520	$11.92M	3.0%	$7.13	+133.5%	COM	45166A102
—	SCPHARMACEUTICALS INC	1,200,647	$10.89M	2.8%	$5.92	—	COM	810648105
—	FIBROGEN INC	579,434	$10.81M	2.8%	$17.63	—	COM	31572Q808
RNAM	AVIDITY BIOSCIENCES INC	665,555	$10.22M	2.6%	$18.92	+16.3%	COM	05370A108
ARVN	ARVINAS INC	320,000	$8.742M	2.2%	$29.28	+7.9%	COM	04335A105
COGT	COGENT BIOSCIENCES INC	790,440	$8.529M	2.2%	$6.91	+85.0%	COM	19240Q201
ANAB	ANAPTYSBIO INC	357,733	$7.784M	2.0%	$28.24	-13.9%	COM	032724106
VRDN	VIRIDIAN THERAPEUTICS INC	280,000	$7.123M	1.8%	$17.98	+78.4%	COM	92790C104
—	IVERIC BIO INC	284,626	$6.925M	1.8%	$16.46	—	COM	46583P102
VKTX	VIKING THERAPEUTICS INC	350,000	$5.827M	1.5%	$10.33	0.0%	COM	92686J106
—	SPRUCE BIOSCIENCES INC	2,364,000	$5.224M	1.3%	$2.21	—	COM	85209E109
—	MERSANA THERAPEUTICS INC	1,185,000	$4.87M	1.2%	$4.11	—	COM	59045L106
PHVS	PHARVARIS N V	587,600	$4.733M	1.2%	$18.63	-52.8%	COM	N69605108
—	HOMOLOGY MEDICINES INC	4,535,919	$4.672M	1.2%	$20.70	—	COM	438083107
—	PEAR THERAPEUTICS INC	16,744,113	$4.27M	1.1%	$6.20	—	CLASS A COM	704723105
—	IMPEL PHARMACEUTICALS INC	2,884,791	$4.039M	1.0%	$8.85	—	COM	45258K109
—	CIDARA THERAPEUTICS INC	1,134,511	$1.441M	0.4%	$3.84	—	COM	171757107
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	38,856	$831K	0.2%	$16.81	0.0%	CLASS A ORD	61559X104