5AM Venture Management, LLC Long-Term Concentrated

CIK: 0001799883 · Show all filings

Period: Q2 2023 (← Previous) (Next →)

Filing Date: Aug 14, 2023

Total Value ($000): $401,433 (100.0% shares, 0.0% debt)

Holdings (24)

ELVN ENLIVEN THERAPEUTICS INC 29.5%

Value ($000) $118,347 Shares 5,798,475 Est. Cost $20.34 Unrealized -0.6%

TRDA ENTRADA THERAPEUTICS INC 16.6%

Value ($000) $66,743 Shares 4,408,379 Est. Cost $17.12 Unrealized —

IRON DISC MEDICINE INC 5.4%

Value ($000) $21,687 Shares 488,442 Est. Cost $49.79 Unrealized -28.7%

— RALLYBIO CORP 5.1%

Value ($000) $20,550 Shares 3,630,724 Est. Cost $17.58 Unrealized —

— VOR BIOPHARMA INC 4.9%

Value ($000) $19,658 Shares 6,361,723 Est. Cost $43.10 Unrealized —

MLTX MOONLAKE IMMUNOTHERAPEUTICS 4.5%

Value ($000) $18,232 Shares 357,486 Est. Cost $25.81 Unrealized +4.3%

CRNX CRINETICS PHARMACEUTICALS IN 3.9%

Value ($000) $15,538 Shares 862,286 Est. Cost $19.04 Unrealized +4.7%

ZNTL ZENTALIS PHARMACEUTICALS INC 3.4%

Value ($000) $13,823 Shares 490,000 Est. Cost $23.99 Unrealized 0.0%

— SCPHARMACEUTICALS INC 3.0%

Value ($000) $12,235 Shares 1,200,647 Est. Cost $5.92 Unrealized —

CLDX CELLDEX THERAPEUTICS INC NEW 2.6%

Value ($000) $10,527 Shares 310,270 Est. Cost $33.70 Unrealized 0.0%

VKTX VIKING THERAPEUTICS INC 2.4%

Value ($000) $9,483 Shares 585,000 Est. Cost $14.60 Unrealized +43.5%

COGT COGENT BIOSCIENCES INC 2.3%

Value ($000) $9,359 Shares 790,440 Est. Cost $6.91 Unrealized +66.0%

PHVS PHARVARIS N V 2.2%

Value ($000) $8,896 Shares 587,600 Est. Cost $18.63 Unrealized -48.3%

ARVN ARVINAS INC 2.0%

Value ($000) $7,942 Shares 320,000 Est. Cost $29.28 Unrealized -12.2%

RNAM AVIDITY BIOSCIENCES INC 1.8%

Value ($000) $7,381 Shares 665,555 Est. Cost $18.92 Unrealized -33.7%

ANAB ANAPTYSBIO INC 1.8%

Value ($000) $7,276 Shares 357,733 Est. Cost $28.24 Unrealized -28.2%

— MIRATI THERAPEUTICS INC 1.7%

Value ($000) $6,955 Shares 192,500 Est. Cost $36.13 Unrealized —

VRDN VIRIDIAN THERAPEUTICS INC 1.7%

Value ($000) $6,661 Shares 280,000 Est. Cost $17.98 Unrealized +42.7%

— SPRUCE BIOSCIENCES INC 1.3%

Value ($000) $5,083 Shares 2,364,000 Est. Cost $2.21 Unrealized —

— MERSANA THERAPEUTICS INC 1.1%

Value ($000) $4,293 Shares 1,305,000 Est. Cost $4.03 Unrealized —

— HOMOLOGY MEDICINES INC 1.0%

Value ($000) $4,014 Shares 4,535,919 Est. Cost $20.70 Unrealized —

— IMPEL PHARMACEUTICALS INC 0.9%

Value ($000) $3,664 Shares 2,884,791 Est. Cost $8.85 Unrealized —

GHRS GH RESEARCH PLC 0.4%

Value ($000) $1,804 Shares 152,022 Est. Cost $10.26 Unrealized 0.0%

— CIDARA THERAPEUTICS INC 0.3%

Value ($000) $1,282 Shares 1,134,511 Est. Cost $3.84 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
ELVN	ENLIVEN THERAPEUTICS INC	5,798,475	$118,347	29.5%	$20.34	-0.6%	COM	29337E102
TRDA	ENTRADA THERAPEUTICS INC	4,408,379	$66,743	16.6%	$17.12	—	COM	29384C108
IRON	DISC MEDICINE INC	488,442	$21,687	5.4%	$49.79	-28.7%	COM	254604101
—	RALLYBIO CORP	3,630,724	$20,550	5.1%	$17.58	—	COM	75120L100
—	VOR BIOPHARMA INC	6,361,723	$19,658	4.9%	$43.10	—	COM	929033108
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	357,486	$18,232	4.5%	$25.81	+4.3%	CLASS A ORD	61559X104
CRNX	CRINETICS PHARMACEUTICALS IN	862,286	$15,538	3.9%	$19.04	+4.7%	COM	22663K107
ZNTL	ZENTALIS PHARMACEUTICALS INC	490,000	$13,823	3.4%	$23.99	0.0%	COM	98943L107
—	SCPHARMACEUTICALS INC	1,200,647	$12,235	3.0%	$5.92	—	COM	810648105
CLDX	CELLDEX THERAPEUTICS INC NEW	310,270	$10,527	2.6%	$33.70	0.0%	COM NEW	15117B202
VKTX	VIKING THERAPEUTICS INC	585,000	$9,483	2.4%	$14.60	+43.5%	COM	92686J106
COGT	COGENT BIOSCIENCES INC	790,440	$9,359	2.3%	$6.91	+66.0%	COM	19240Q201
PHVS	PHARVARIS N V	587,600	$8,896	2.2%	$18.63	-48.3%	COM	N69605108
ARVN	ARVINAS INC	320,000	$7,942	2.0%	$29.28	-12.2%	COM	04335A105
RNAM	AVIDITY BIOSCIENCES INC	665,555	$7,381	1.8%	$18.92	-33.7%	COM	05370A108
ANAB	ANAPTYSBIO INC	357,733	$7,276	1.8%	$28.24	-28.2%	COM	032724106
—	MIRATI THERAPEUTICS INC	192,500	$6,955	1.7%	$36.13	—	COM	60468T105
VRDN	VIRIDIAN THERAPEUTICS INC	280,000	$6,661	1.7%	$17.98	+42.7%	COM	92790C104
—	SPRUCE BIOSCIENCES INC	2,364,000	$5,083	1.3%	$2.21	—	COM	85209E109
—	MERSANA THERAPEUTICS INC	1,305,000	$4,293	1.1%	$4.03	—	COM	59045L106
—	HOMOLOGY MEDICINES INC	4,535,919	$4,014	1.0%	$20.70	—	COM	438083107
—	IMPEL PHARMACEUTICALS INC	2,884,791	$3,664	0.9%	$8.85	—	COM	45258K109
GHRS	GH RESEARCH PLC	152,022	$1,804	0.4%	$10.26	0.0%	ORDINARY SHARES	G3855L106
—	CIDARA THERAPEUTICS INC	1,134,511	$1,282	0.3%	$3.84	—	COM	171757107