5AM Venture Management, LLC Long-Term Concentrated

Location: San Francisco, CA

CIK: 0001799883 · Show all filings

Period: Q2 2023 (← Previous) (Next →)

Filing Date: Aug 14, 2023

Total Value: $401M (100.0% shares, 0.0% debt)

Holdings (24)

ELVN ENLIVEN THERAPEUTICS INC 29.5%

Value $118M Shares 5,798,475 Est. Cost $20.34 Unrealized -0.6%

TRDA ENTRADA THERAPEUTICS INC 16.6%

Value $66.74M Shares 4,408,379 Est. Cost $17.12 Unrealized —

IRON DISC MEDICINE INC 5.4%

Value $21.69M Shares 488,442 Est. Cost $49.79 Unrealized -28.7%

— RALLYBIO CORP 5.1%

Value $20.55M Shares 3,630,724 Est. Cost $17.58 Unrealized —

— VOR BIOPHARMA INC 4.9%

Value $19.66M Shares 6,361,723 Est. Cost $43.10 Unrealized —

MLTX MOONLAKE IMMUNOTHERAPEUTICS 4.5%

Value $18.23M Shares 357,486 Est. Cost $25.81 Unrealized +4.3%

CRNX CRINETICS PHARMACEUTICALS IN 3.9%

Value $15.54M Shares 862,286 Est. Cost $19.04 Unrealized +4.7%

ZNTL ZENTALIS PHARMACEUTICALS INC 3.4%

Value $13.82M Shares 490,000 Est. Cost $23.99 Unrealized 0.0%

— SCPHARMACEUTICALS INC 3.0%

Value $12.23M Shares 1,200,647 Est. Cost $5.92 Unrealized —

CLDX CELLDEX THERAPEUTICS INC NEW 2.6%

Value $10.53M Shares 310,270 Est. Cost $33.70 Unrealized 0.0%

VKTX VIKING THERAPEUTICS INC 2.4%

Value $9.483M Shares 585,000 Est. Cost $14.60 Unrealized +43.5%

COGT COGENT BIOSCIENCES INC 2.3%

Value $9.359M Shares 790,440 Est. Cost $6.91 Unrealized +66.0%

PHVS PHARVARIS N V 2.2%

Value $8.896M Shares 587,600 Est. Cost $18.63 Unrealized -48.3%

ARVN ARVINAS INC 2.0%

Value $7.942M Shares 320,000 Est. Cost $29.28 Unrealized -12.2%

RNAM AVIDITY BIOSCIENCES INC 1.8%

Value $7.381M Shares 665,555 Est. Cost $18.92 Unrealized -33.7%

ANAB ANAPTYSBIO INC 1.8%

Value $7.276M Shares 357,733 Est. Cost $28.24 Unrealized -28.2%

— MIRATI THERAPEUTICS INC 1.7%

Value $6.955M Shares 192,500 Est. Cost $36.13 Unrealized —

VRDN VIRIDIAN THERAPEUTICS INC 1.7%

Value $6.661M Shares 280,000 Est. Cost $17.98 Unrealized +42.7%

— SPRUCE BIOSCIENCES INC 1.3%

Value $5.083M Shares 2,364,000 Est. Cost $2.21 Unrealized —

— MERSANA THERAPEUTICS INC 1.1%

Value $4.293M Shares 1,305,000 Est. Cost $4.03 Unrealized —

— HOMOLOGY MEDICINES INC 1.0%

Value $4.014M Shares 4,535,919 Est. Cost $20.70 Unrealized —

— IMPEL PHARMACEUTICALS INC 0.9%

Value $3.664M Shares 2,884,791 Est. Cost $8.85 Unrealized —

GHRS GH RESEARCH PLC 0.4%

Value $1.804M Shares 152,022 Est. Cost $10.26 Unrealized 0.0%

— CIDARA THERAPEUTICS INC 0.3%

Value $1.282M Shares 1,134,511 Est. Cost $3.84 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ELVN	ENLIVEN THERAPEUTICS INC	5,798,475	$118M	29.5%	$20.34	-0.6%	COM	29337E102
TRDA	ENTRADA THERAPEUTICS INC	4,408,379	$66.74M	16.6%	$17.12	—	COM	29384C108
IRON	DISC MEDICINE INC	488,442	$21.69M	5.4%	$49.79	-28.7%	COM	254604101
—	RALLYBIO CORP	3,630,724	$20.55M	5.1%	$17.58	—	COM	75120L100
—	VOR BIOPHARMA INC	6,361,723	$19.66M	4.9%	$43.10	—	COM	929033108
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	357,486	$18.23M	4.5%	$25.81	+4.3%	CLASS A ORD	61559X104
CRNX	CRINETICS PHARMACEUTICALS IN	862,286	$15.54M	3.9%	$19.04	+4.7%	COM	22663K107
ZNTL	ZENTALIS PHARMACEUTICALS INC	490,000	$13.82M	3.4%	$23.99	0.0%	COM	98943L107
—	SCPHARMACEUTICALS INC	1,200,647	$12.23M	3.0%	$5.92	—	COM	810648105
CLDX	CELLDEX THERAPEUTICS INC NEW	310,270	$10.53M	2.6%	$33.70	0.0%	COM NEW	15117B202
VKTX	VIKING THERAPEUTICS INC	585,000	$9.483M	2.4%	$14.60	+43.5%	COM	92686J106
COGT	COGENT BIOSCIENCES INC	790,440	$9.359M	2.3%	$6.91	+66.0%	COM	19240Q201
PHVS	PHARVARIS N V	587,600	$8.896M	2.2%	$18.63	-48.3%	COM	N69605108
ARVN	ARVINAS INC	320,000	$7.942M	2.0%	$29.28	-12.2%	COM	04335A105
RNAM	AVIDITY BIOSCIENCES INC	665,555	$7.381M	1.8%	$18.92	-33.7%	COM	05370A108
ANAB	ANAPTYSBIO INC	357,733	$7.276M	1.8%	$28.24	-28.2%	COM	032724106
—	MIRATI THERAPEUTICS INC	192,500	$6.955M	1.7%	$36.13	—	COM	60468T105
VRDN	VIRIDIAN THERAPEUTICS INC	280,000	$6.661M	1.7%	$17.98	+42.7%	COM	92790C104
—	SPRUCE BIOSCIENCES INC	2,364,000	$5.083M	1.3%	$2.21	—	COM	85209E109
—	MERSANA THERAPEUTICS INC	1,305,000	$4.293M	1.1%	$4.03	—	COM	59045L106
—	HOMOLOGY MEDICINES INC	4,535,919	$4.014M	1.0%	$20.70	—	COM	438083107
—	IMPEL PHARMACEUTICALS INC	2,884,791	$3.664M	0.9%	$8.85	—	COM	45258K109
GHRS	GH RESEARCH PLC	152,022	$1.804M	0.4%	$10.26	0.0%	ORDINARY SHARES	G3855L106
—	CIDARA THERAPEUTICS INC	1,134,511	$1.282M	0.3%	$3.84	—	COM	171757107