Redmile Group, LLC Diversified Active

Location: Larkspur, CA

CIK: 0001425738 · Show all filings

Period: Q4 2025 (← Previous) (Next →)

Filing Date: Feb 17, 2026

Total Value: $1.358B (100.0% shares, 0.0% debt)

Holdings (34)

SRRK SCHOLAR ROCK HLDG CORP 16.9%

Value $230M Shares 5,220,846 Share Price $44.05 * Est. Cost/Share $18.57 Unrealized @ Report Date +102.0%

KRYS KRYSTAL BIOTECH INC 12.3%

Value $167M Shares 677,705 Share Price $246.54 * Est. Cost/Share $62.38 Unrealized @ Report Date +237.4%

NRIX NURIX THERAPEUTICS INC 11.3%

Value $154M Shares 8,093,908 Share Price $18.97 * Est. Cost/Share $17.18 Unrealized @ Report Date -16.4%

STOK STOKE THERAPEUTICS INC 9.4%

Value $128M Shares 4,034,070 Share Price $31.74 * Est. Cost/Share $9.00 Unrealized @ Report Date +234.1%

IMNM IMMUNOME INC 9.0%

Value $123M Shares 5,718,385 Share Price $21.48 * Est. Cost/Share $11.49 Unrealized @ Report Date +52.8%

RGNX REGENXBIO INC 4.6%

Value $62.91M Shares 4,368,804 Share Price $14.40 * Est. Cost/Share $22.74 Unrealized @ Report Date -45.2%

ADCT ADC THERAPEUTICS SA 4.1%

Value $55.3M Shares 15,666,731 Share Price $3.53 * Est. Cost/Share $19.52 Unrealized @ Report Date -79.2%

COGT COGENT BIOSCIENCES INC 3.8%

Value $51.07M Shares 1,437,918 Share Price $35.52 * Est. Cost/Share $9.95 Unrealized @ Report Date +182.5%

ANNX ANNEXON INC 3.7%

Value $50.45M Shares 10,050,644 Share Price $5.02 * Est. Cost/Share $9.79 Unrealized @ Report Date -61.0%

BEAM BEAM THERAPEUTICS INC 2.6%

Value $35.64M Shares 1,285,859 Share Price $27.72 * Est. Cost/Share $26.47 Unrealized @ Report Date -3.6%

NGNE NEUROGENE INC 2.2%

Value $30.07M Shares 1,459,599 Share Price $20.60 * Est. Cost/Share $22.00 Unrealized @ Report Date +13.1%

RAPT RAPT THERAPEUTICS INC 2.2%

Value $30.01M Shares 885,927 Share Price $33.87 * Est. Cost/Share $16.44 Unrealized @ Report Date +88.9%

ABSI ABSCI CORPORATION 2.1%

Value $28.8M Shares 8,253,316 Share Price $3.49 * Est. Cost/Share $19.01 Unrealized @ Report Date -80.8%

NUVB NUVATION BIO INC 2.1%

Value $28.34M Shares 3,163,256 Share Price $8.96 * Est. Cost/Share $10.97 Unrealized @ Report Date -43.5%

IDYA IDEAYA BIOSCIENCES INC 1.9%

Value $25.65M Shares 742,017 Share Price $34.57 * Est. Cost/Share $27.49 Unrealized @ Report Date +16.0%

STTK SHATTUCK LABS INC 1.5%

Value $20.22M Shares 5,539,724 Share Price $3.65 * Est. Cost/Share $32.14 Unrealized @ Report Date -92.6%

SLN SILENCE THERAPEUTICS PLC 1.0%

Value $13.16M Shares 2,164,777 Share Price $6.08 Est. Cost/Share $18.53 Unrealized @ Report Date —

ZYME ZYMEWORKS INC 1.0%

Value $12.95M Shares 491,654 Share Price $26.33 * Est. Cost/Share $7.05 Unrealized @ Report Date +209.5%

FATE FATE THERAPEUTICS INC 0.9%

Value $12.65M Shares 12,872,946 Share Price $0.98 * Est. Cost/Share $13.12 Unrealized @ Report Date -90.9%

REPL REPLIMUNE GROUP INC 0.8%

Value $10.69M Shares 1,099,756 Share Price $9.72 * Est. Cost/Share $12.40 Unrealized @ Report Date -31.5%

DBVT DBV TECHNOLOGIES S A 0.8%

Value $10.54M Shares 549,840 Share Price $19.17 Est. Cost/Share $19.17 Unrealized @ Report Date —

SLDB SOLID BIOSCIENCES INC 0.8%

Value $10.49M Shares 1,860,542 Share Price $5.64 * Est. Cost/Share $4.65 Unrealized @ Report Date +16.5%

CBLL CERIBELL INC 0.7%

Value $9.545M Shares 435,239 Share Price $21.93 * Est. Cost/Share $27.25 Unrealized @ Report Date -43.0%

ESTA ESTABLISHMENT LABS HLDGS INC 0.6%

Value $8.211M Shares 112,664 Share Price $72.88 * Est. Cost/Share $44.21 Unrealized @ Report Date +36.6%

ATRA ATARA BIOTHERAPEUTICS INC 0.6%

Value $7.99M Shares 441,701 Share Price $18.09 * Est. Cost/Share $15.04 Unrealized @ Report Date -0.7%

CLDX CELLDEX THERAPEUTICS INC NEW 0.6%

Value $7.695M Shares 283,308 Share Price $27.16 * Est. Cost/Share $11.60 Unrealized @ Report Date +127.1%

LIVN LIVANOVA PLC 0.5%

Value $7.264M Shares 118,054 Share Price $61.53 * Est. Cost/Share $70.40 Unrealized @ Report Date -18.8%

IVVD INVIVYD INC 0.5%

Value $6.622M Shares 2,681,159 Share Price $2.47 * Est. Cost/Share $16.17 Unrealized @ Report Date -87.1%

XENE XENON PHARMACEUTICALS INC 0.4%

Value $6.001M Shares 133,882 Share Price $44.82 * Est. Cost/Share $42.00 Unrealized @ Report Date 0.0%

— REPARE THERAPEUTICS INC 0.3%

Value $4.124M Shares 1,586,174 Share Price $2.60 Est. Cost/Share $30.51 Unrealized @ Report Date —

ALXO ALX ONCOLOGY HLDGS INC 0.3%

Value $3.689M Shares 3,264,718 Share Price $1.13 * Est. Cost/Share $15.46 Unrealized @ Report Date -90.2%

ORIC ORIC PHARMACEUTICALS INC 0.3%

Value $3.666M Shares 448,110 Share Price $8.18 * Est. Cost/Share $11.51 Unrealized @ Report Date 0.0%

PLRX PLIANT THERAPEUTICS INC 0.1%

Value $1.972M Shares 1,616,228 Share Price $1.22 * Est. Cost/Share $22.50 Unrealized @ Report Date -93.3%

KLRS KALARIS THERAPEUTICS INC 0.1%

Value $700K Shares 82,955 Share Price $8.44 * Est. Cost/Share $9.79 Unrealized @ Report Date -34.7%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
SRRK	SCHOLAR ROCK HLDG CORP	5,220,846	$230M	16.9%	$44.05 *	$18.57	+102.0%	COM	80706P103
KRYS	KRYSTAL BIOTECH INC	677,705	$167M	12.3%	$246.54 *	$62.38	+237.4%	COM	501147102
NRIX	NURIX THERAPEUTICS INC	8,093,908	$154M	11.3%	$18.97 *	$17.18	-16.4%	COM	67080M103
STOK	STOKE THERAPEUTICS INC	4,034,070	$128M	9.4%	$31.74 *	$9.00	+234.1%	COM	86150R107
IMNM	IMMUNOME INC	5,718,385	$123M	9.0%	$21.48 *	$11.49	+52.8%	COM	45257U108
RGNX	REGENXBIO INC	4,368,804	$62.91M	4.6%	$14.40 *	$22.74	-45.2%	COM	75901B107
ADCT	ADC THERAPEUTICS SA	15,666,731	$55.3M	4.1%	$3.53 *	$19.52	-79.2%	SHS	H0036K147
COGT	COGENT BIOSCIENCES INC	1,437,918	$51.07M	3.8%	$35.52 *	$9.95	+182.5%	COM	19240Q201
ANNX	ANNEXON INC	10,050,644	$50.45M	3.7%	$5.02 *	$9.79	-61.0%	COM	03589W102
BEAM	BEAM THERAPEUTICS INC	1,285,859	$35.64M	2.6%	$27.72 *	$26.47	-3.6%	COM	07373V105
NGNE	NEUROGENE INC	1,459,599	$30.07M	2.2%	$20.60 *	$22.00	+13.1%	COM	64135M105
RAPT	RAPT THERAPEUTICS INC	885,927	$30.01M	2.2%	$33.87 *	$16.44	+88.9%	COM NEW	75382E208
ABSI	ABSCI CORPORATION	8,253,316	$28.8M	2.1%	$3.49 *	$19.01	-80.8%	COM	00091E109
NUVB	NUVATION BIO INC	3,163,256	$28.34M	2.1%	$8.96 *	$10.97	-43.5%	COM CL A	67080N101
IDYA	IDEAYA BIOSCIENCES INC	742,017	$25.65M	1.9%	$34.57 *	$27.49	+16.0%	COM	45166A102
STTK	SHATTUCK LABS INC	5,539,724	$20.22M	1.5%	$3.65 *	$32.14	-92.6%	COM	82024L103
SLN	SILENCE THERAPEUTICS PLC	2,164,777	$13.16M	1.0%	$6.08	$18.53	—	ADS	82686Q101
ZYME	ZYMEWORKS INC	491,654	$12.95M	1.0%	$26.33 *	$7.05	+209.5%	COM	98985Y108
FATE	FATE THERAPEUTICS INC	12,872,946	$12.65M	0.9%	$0.98 *	$13.12	-90.9%	COM	31189P102
REPL	REPLIMUNE GROUP INC	1,099,756	$10.69M	0.8%	$9.72 *	$12.40	-31.5%	COM	76029N106
DBVT	DBV TECHNOLOGIES S A	549,840	$10.54M	0.8%	$19.17	$19.17	—	SPONSORED ADS	23306J309
SLDB	SOLID BIOSCIENCES INC	1,860,542	$10.49M	0.8%	$5.64 *	$4.65	+16.5%	COM NEW	83422E204
CBLL	CERIBELL INC	435,239	$9.545M	0.7%	$21.93 *	$27.25	-43.0%	COM	15678C102
ESTA	ESTABLISHMENT LABS HLDGS INC	112,664	$8.211M	0.6%	$72.88 *	$44.21	+36.6%	COM	G31249108
ATRA	ATARA BIOTHERAPEUTICS INC	441,701	$7.99M	0.6%	$18.09 *	$15.04	-0.7%	COM NEW	046513206
CLDX	CELLDEX THERAPEUTICS INC NEW	283,308	$7.695M	0.6%	$27.16 *	$11.60	+127.1%	COM NEW	15117B202
LIVN	LIVANOVA PLC	118,054	$7.264M	0.5%	$61.53 *	$70.40	-18.8%	SHS	G5509L101
IVVD	INVIVYD INC	2,681,159	$6.622M	0.5%	$2.47 *	$16.17	-87.1%	COM	00534A102
XENE	XENON PHARMACEUTICALS INC	133,882	$6.001M	0.4%	$44.82 *	$42.00	0.0%	COM	98420N105
—	REPARE THERAPEUTICS INC	1,586,174	$4.124M	0.3%	$2.60	$30.51	—	COM	760273102
ALXO	ALX ONCOLOGY HLDGS INC	3,264,718	$3.689M	0.3%	$1.13 *	$15.46	-90.2%	COM	00166B105
ORIC	ORIC PHARMACEUTICALS INC	448,110	$3.666M	0.3%	$8.18 *	$11.51	0.0%	COM	68622P109
PLRX	PLIANT THERAPEUTICS INC	1,616,228	$1.972M	0.1%	$1.22 *	$22.50	-93.3%	COM	729139105
KLRS	KALARIS THERAPEUTICS INC	82,955	$700K	0.1%	$8.44 *	$9.79	-34.7%	COM	482929106