Location: Miami Beach, FL
CIK: 0001535610 · Show all filings
Period: Q4 2013 (← Previous) (Next →)
Filing Date: Feb 14, 2014
Total Value: $1.568B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | VERTEX PHARMACEUTICALS INC | 26,661 | $198M | 12.6% | $7429.99 | — | — | Call | 92532F900 |
| — | SPDR S&P 500 ETF TRUST | 8,933 | $165M | 10.5% | $18467.03 | — | — | Call | 78462F903 |
| — | ACADIA PHARMACEUTICALS INC | 29,863 | $74.63M | 4.8% | $2499.01 | — | — | Call | 004225909 |
| — | VERTEX PHARMACEUTICALS INC | 9,768 | $72.58M | 4.6% | $7429.98 | — | — | Put | 92532F950 |
| — | MERCK & CO INC | 12,832 | $64.22M | 4.1% | $5004.99 | — | — | Call | 58933Y905 |
| — | ALLERGAN INC | 5,589 | $62.08M | 4.0% | $11108.07 | — | — | Call | 018490902 |
| — | ISHARES RUSSELL 2000 | 5,000 | $57.66M | 3.7% | $11531.00 | — | — | Call | 464287905 |
| — | GILEAD SCIENCES INC | 6,808 | $51.16M | 3.3% | $7514.98 | — | — | Put | 375558953 |
| — | BRISTOL MYERS SQUIBB CO | 9,493 | $50.45M | 3.2% | $5314.97 | — | — | Call | 110122908 |
| — | TEVA PHARMACEUTICAL INDUSTRIES LTD | 8,505 | $34.09M | 2.2% | $4008.00 | — | — | Put | 881624959 |
| — | GLAXOSMITHKLINE PLC | 6,300 | $33.64M | 2.1% | $5339.05 | — | — | Call | 37733W905 |
| — | MEDIVATION INC | 4,918 | $31.39M | 2.0% | $6382.07 | — | — | Put | 58501N951 |
| — | SPDR S&P BIOTECHNOLOGY | 2,164 | $28.18M | 1.8% | $13019.87 | — | — | Put | 78464A950 |
| — | BIOGEN IDEC INC | 903 | $25.26M | 1.6% | $27974.53 | — | — | Call | 09062X903 |
| — | SPDR S&P 500 ETF TRUST | 1,338 | $24.71M | 1.6% | $18467.12 | — | — | Put | 78462F953 |
| — | CUBIST PHARMACEUTICALS INC | 3,370 | $23.21M | 1.5% | $6886.94 | — | — | Put | 229678957 |
| — | ISHARES RUSSELL 2000 | 2,000 | $23.06M | 1.5% | $11531.00 | — | — | Put | 464287955 |
| — | MANNKIND CORP | 3,931,850 | $20.48M | 1.3% | $5.21 | $5.35 | — | COM | 56400P201 |
| TEVA | TEVA PHARMACEUTICAL INDUSTRIES LTD | 466,312 | $18.69M | 1.2% | $40.08 | $40.00 | — | ADR | 881624209 |
| — | ALLERGAN INC | 1,616 | $17.95M | 1.1% | $11108.29 | — | — | Put | 018490952 |
| — | REGENERON PHARMACEUTICALS INC | 652 | $17.95M | 1.1% | $27524.54 | — | — | Call | 75886F907 |
| — | OPKO HEALTH INC | 19,558 | $16.51M | 1.1% | $844.00 | — | — | Call | 68375N903 |
| — | MANNKIND CORP | 30,592 | $15.94M | 1.0% | $520.99 | — | — | Call | 56400P901 |
| — | SAREPTA THERAPEUTICS INC | 7,473 | $15.22M | 1.0% | $2037.07 | — | — | Put | 803607950 |
| — | GILEAD SCIENCES INC | 2,000 | $15.03M | 1.0% | $7515.00 | — | — | Call | 375558903 |
| BAX | BAXTER INTERNATIONAL INC | 2,158 | $15.01M | 1.0% | $6955.05 | — | — | Call | 071813109 |
| — | WELLCARE HEALTH PLANS INC | 2,082 | $14.66M | 0.9% | $7041.79 | — | — | Call | 94946T906 |
| ACAD | ACADIA PHARMACEUTICALS INC | 557,013 | $13.92M | 0.9% | $24.99 * | $16.07 | +46.8% | COM | 004225108 |
| — | KERYX BIOPHARMACEUTICALS | 10,147 | $13.14M | 0.8% | $1294.96 | — | — | Call | 492515901 |
| — | AEGERION PHARMACEUTICALS INC | 1,820 | $12.91M | 0.8% | $7096.15 | — | — | Put | 00767E952 |
| — | EDWARDS LIFESCIENCES CORP | 1,698 | $11.17M | 0.7% | $6575.97 | — | — | Call | 28176E908 |
| — | CELGENE CORP | 648 | $10.95M | 0.7% | $16896.60 | — | — | Put | 151020954 |
| — | NEWLINK GENETICS CORP | 4,879 | $10.74M | 0.7% | $2201.07 | — | — | Call | 651511907 |
| SRPT | SAREPTA THERAPEUTICS INC | 507,700 | $10.34M | 0.7% | $20.37 * | $36.12 | -17.7% | COM | 803607100 |
| — | AEGERION PHARMACEUTICALS INC | 1,375 | $9.757M | 0.6% | $7096.00 | — | — | Call | 00767E902 |
| — | ISIS PHARMACEUTICALS INC | 2,336 | $9.307M | 0.6% | $3984.16 | — | — | Put | 464330959 |
| — | MANNKIND CORP | 16,678 | $8.689M | 0.6% | $520.99 | — | — | Put | 56400P951 |
| — | AEGERION PHARMACEUTICALS INC | 116,626 | $8.276M | 0.5% | $70.96 | $63.34 | — | COM | 00767E102 |
| — | CELLDEX THERAPEUTICS INC | 3,382 | $8.188M | 0.5% | $2421.05 | — | — | Call | 15117B903 |
| — | LIGAND PHARMACEUTICALS INC | 1,541 | $8.106M | 0.5% | $5260.22 | — | — | Call | 53220K904 |
| — | OPKO HEALTH INC | 9,427 | $7.956M | 0.5% | $843.96 | — | — | Put | 68375N953 |
| — | ACHILLION PHARMACEUTICALS INC | 22,579 | $7.496M | 0.5% | $331.99 | — | — | Call | 00448Q901 |
| — | INTERMUNE INC | 4,192 | $6.175M | 0.4% | $1473.04 | — | — | Call | 45884X903 |
| — | BIOGEN IDEC INC | 218 | $6.099M | 0.4% | $27977.06 | — | — | Put | 09062X953 |
| GILD | GILEAD SCIENCES INC | 78,000 | $5.862M | 0.4% | $75.15 * | $36.21 | +33.6% | COM | 375558103 |
| — | ARENA PHARMACEUTICALS INC | 9,181 | $5.371M | 0.3% | $585.01 | — | — | Call | 040047902 |
| — | REPROS THERAPEUTICS INC | 2,935 | $5.371M | 0.3% | $1829.98 | — | — | Put | 76028H959 |
| — | ANTHERA PHARMACEUTICALS INC | 1,714,958 | $5.265M | 0.3% | $3.07 | $4.02 | — | COM | 03674U201 |
| — | ALEXION PHARMACEUTICALS INC | 389 | $5.176M | 0.3% | $13305.91 | — | — | Call | 015351909 |
| — | MEDIVATION INC | 75,016 | $4.788M | 0.3% | $63.83 | $55.38 | — | COM | 58501N101 |
| — | TWITTER INC | 72,300 | $4.602M | 0.3% | $63.65 | $63.65 | — | COM | 90184L102 |
| — | MOMENTA PHARMACEUTICALS INC | 2,587 | $4.574M | 0.3% | $1768.07 | — | — | Call | 60877T900 |
| — | GALENA BIOPHARMA INC | 9,121 | $4.524M | 0.3% | $496.00 | — | — | Put | 363256958 |
| — | SAREPTA THERAPEUTICS INC | 2,107 | $4.292M | 0.3% | $2037.02 | — | — | Call | 803607900 |
| — | ARENA PHARMACEUTICALS INC | 7,322 | $4.283M | 0.3% | $584.95 | — | — | Put | 040047952 |
| — | TEKMIRA PHARMACEUTICALS CORP | 519,200 | $4.138M | 0.3% | $7.97 | $7.97 | — | COM | 87911B209 |
| — | CELSION CORPORATION | 9,364 | $3.643M | 0.2% | $389.04 | — | — | Put | 15117N954 |
| — | CELGENE CORP | 210 | $3.548M | 0.2% | $16895.24 | — | — | Call | 151020904 |
| — | INSMED INC | 1,991 | $3.387M | 0.2% | $1701.16 | — | — | Call | 457669907 |
| — | ARIAD PHARMACEUTICALS INC | 4,880 | $3.328M | 0.2% | $681.97 | — | — | Call | 04033A900 |
| — | ONCOGENEX PHARMACEUTICAL INC | 352,800 | $2.942M | 0.2% | $8.34 | $9.78 | — | COM | 68230A106 |
| — | INSMED INC | 1,727 | $2.938M | 0.2% | $1701.22 | — | — | Put | 457669957 |
| — | CEMPRA INC | 237,000 | $2.936M | 0.2% | $12.39 | $9.53 | — | COM | 15130J109 |
| — | XOMA CORP | 413,390 | $2.782M | 0.2% | $6.73 | $4.48 | — | COM | 98419J107 |
| — | MELA SCIENCES INC | 4,290,716 | $2.746M | 0.2% | $0.64 | $0.64 | — | COM | 55277R100 |
| — | AVEO PHARMACEUTICALS INC | 1,490,121 | $2.742M | 0.2% | $1.84 | $1.84 | — | COM | 053588109 |
| ABBV | ABBVIE INC | 517 | $2.73M | 0.2% | $5280.46 | — | — | Call | 00287Y109 |
| — | INTERMUNE INC | 1,838 | $2.707M | 0.2% | $1472.80 | — | — | Put | 45884X953 |
| — | TEVA PHARMACEUTICAL INDUSTRIES LTD | 667 | $2.673M | 0.2% | $4007.50 | — | — | Call | 881624909 |
| — | ADAMIS PHARMACEUTICALS CORP | 407,024 | $2.601M | 0.2% | $6.39 | $6.39 | — | COM | 00547W208 |
| — | CUBIST PHARMACEUTICALS INC | 1,329 | $2.591M | 0.2% | $1949.59 | — | — | Call | 229678907 |
| — | KYTHERA BIOPHARMACEUTICALS INC | 66,200 | $2.466M | 0.2% | $37.25 | $37.25 | — | COM | 501570105 |
| — | EXELIXIS INC | 3,960 | $2.427M | 0.2% | $612.88 | — | — | Call | 30161Q904 |
| ENTA | ENANTA PHARMACEUTICALS INC | 85,946 | $2.345M | 0.1% | $27.28 * | $24.23 | 0.0% | COM | 29251M106 |
| — | CELSION CORPORATION | 5,990 | $2.33M | 0.1% | $388.98 | — | — | Call | 15117N904 |
| — | NUPATHE INC | 7,014 | $2.294M | 0.1% | $327.06 | — | — | Put | 67059M950 |
| EDAP | EDAP TMS SA -ADR | 770,618 | $2.289M | 0.1% | $2.97 | $2.72 | — | ADR | 268311107 |
| — | ALCOBRA LTD | 126,629 | $2.278M | 0.1% | $17.99 | $17.99 | — | SHS | M2239P109 |
| — | ENTREMED INC | 1,289,929 | $2.206M | 0.1% | $1.71 | $1.99 | — | COM | 29382F202 |
| — | INCYTE CORP | 431 | $2.182M | 0.1% | $5062.65 | — | — | Call | 45337C902 |
| — | CELATOR PHARMACEUTICALS INC | 679,592 | $2.181M | 0.1% | $3.21 | $3.21 | — | COM | 15089R102 |
| — | RIGEL PHARMACEUTICALS INC | 762,900 | $2.174M | 0.1% | $2.85 | $3.04 | — | COM | 766559603 |
| — | ROCKWELL MEDICAL INC | 1,976 | $2.171M | 0.1% | $1098.68 | — | — | Put | 774374952 |
| — | BLUEBIRD BIO INC | 102,035 | $2.141M | 0.1% | $20.98 | $20.98 | — | COM | 09609G100 |
| — | ELI LILLY & CO | 407 | $2.076M | 0.1% | $5100.74 | — | — | Put | 532457958 |
| LLY | ELI LILLY & CO | 40,700 | $2.076M | 0.1% | $51.01 * | $41.28 | -4.1% | COM | 532457108 |
| — | PUMA BIOTECHNOLOGY INC | 192 | $1.988M | 0.1% | $10354.17 | — | — | Call | 74587V907 |
| — | SYNAGEVA BIOPHARMA CORP | 285 | $1.845M | 0.1% | $6473.68 | — | — | Call | 87159A903 |
| VNDA | VANDA PHARMACEUTICALS INC | 146,350 | $1.816M | 0.1% | $12.41 * | $10.09 | 0.0% | COM | 921659108 |
| — | LEXICON PHARMACEUTICALS INC | 1,000,000 | $1.8M | 0.1% | $1.80 | $1.80 | — | COM | 528872104 |
| SRNE | SORRENTO THERAPEUTICS INC | 222,026 | $1.798M | 0.1% | $8.10 * | $8.66 | 0.0% | COM | 83587F202 |
| — | CELLDEX THERAPEUTICS INC | 688 | $1.666M | 0.1% | $2421.51 | — | — | Put | 15117B953 |
| — | EXACT SCIENCES CORP | 1,395 | $1.631M | 0.1% | $1169.18 | — | — | Put | 30063P955 |
| — | DELCATH SYSTEMS INC | 6,246,652 | $1.593M | 0.1% | $0.26 | $0.26 | — | COM | 24661P104 |
| — | ARIAD PHARMACEUTICALS INC | 2,309 | $1.575M | 0.1% | $682.11 | — | — | Put | 04033A950 |
| — | ACHILLION PHARMACEUTICALS INC | 453,380 | $1.505M | 0.1% | $3.32 | $3.02 | — | COM | 00448Q201 |
| — | VIVUS INC | 1,597 | $1.45M | 0.1% | $907.95 | — | — | Put | 928551950 |
| — | ACADIA PHARMACEUTICALS INC | 569 | $1.422M | 0.1% | $2499.12 | — | — | Put | 004225959 |
| — | OVASCIENCE INC | 152,336 | $1.392M | 0.1% | $9.14 | $9.91 | — | COM | 69014Q101 |
| — | ARROWHEAD RESEARCH CORP | 1,246 | $1.352M | 0.1% | $1085.07 | — | — | Call | 042797909 |
| — | DISCOVERY LABORATORIES INC | 600,000 | $1.35M | 0.1% | $2.25 | $2.25 | — | COM | 254668403 |
| — | STEMLINE THERAPEUTICS INC | 68,100 | $1.335M | 0.1% | $19.60 | $19.60 | — | COM | 85858C107 |
| — | OREXIGEN THERAPEUTICS INC | 2,261 | $1.273M | 0.1% | $563.03 | — | — | Call | 686164904 |
| — | ONCOTHYREON INC | 718,000 | $1.264M | 0.1% | $1.76 | $2.04 | — | COM | 682324108 |
| — | BRISTOL MYERS SQUIBB CO | 232 | $1.233M | 0.1% | $5314.66 | — | — | Put | 110122958 |
| — | NEUROCRINE BIOSCIENCES INC | 1,307 | $1.221M | 0.1% | $934.20 | — | — | Call | 64125C909 |
| — | BIOCRYST PHARMACEUTICALS INC | 1,576 | $1.198M | 0.1% | $760.15 | — | — | Call | 09058V903 |
| — | EXACT SCIENCES CORP | 1,025 | $1.198M | 0.1% | $1168.78 | — | — | Call | 30063P905 |
| — | ZIOPHARM ONCOLOGY INC | 2,577 | $1.118M | 0.1% | $433.84 | — | — | Call | 98973P901 |
| — | ZIOPHARM ONCOLOGY INC | 2,567 | $1.114M | 0.1% | $433.97 | — | — | Put | 98973P951 |
| — | CHELSEA THERAPEUTICS INTERNATIONAL LTD | 2,509 | $1.113M | 0.1% | $443.60 | — | — | Put | 163428955 |
| — | MEI PHARMA INC | 138,000 | $1.105M | 0.1% | $8.01 | $8.01 | — | COM | 55279B202 |
| — | AVANIR PHARMACEUTICALS INC | 3,264 | $1.097M | 0.1% | $336.09 | — | — | Put | 05348P951 |
| — | STAAR SURGICAL CO | 676 | $1.094M | 0.1% | $1618.34 | — | — | Call | 852312905 |
| — | HALOZYME THERAPEUTICS INC | 700 | $1.049M | 0.1% | $1498.57 | — | — | Call | 40637H909 |
| — | STEMCELLS INC | 846,622 | $1.041M | 0.1% | $1.23 | $1.23 | — | COM | 85857R204 |
| — | DYAX CORP | 136,581 | $1.028M | 0.1% | $7.53 | $7.04 | — | COM | 26746E103 |
| — | NOVAVAX INC | 1,922 | $984K | 0.1% | $511.97 | — | — | Put | 670002954 |
| — | CEL-SCI CORP | 1,662,788 | $983K | 0.1% | $0.59 | $0.59 | — | COM | 150837508 |
| — | DYNAVAX TECHNOLOGIES CORP | 500,000 | $980K | 0.1% | $1.96 | $1.96 | — | COM | 268158102 |
| — | ENDOCYTE INC | 910 | $973K | 0.1% | $1069.23 | — | — | Put | 29269A952 |
| — | ARROWHEAD RESEARCH CORP | 895 | $971K | 0.1% | $1084.92 | — | — | Put | 042797959 |
| INFIQ | INFINITY PHARMACEUTICALS INC | 70,000 | $967K | 0.1% | $13.81 * | $14.12 | 0.0% | COM | 45665G303 |
| — | ALEXZA PHARMACEUTICALS INC | 2,040 | $965K | 0.1% | $473.04 | — | — | Call | 015384909 |
| — | INCYTE CORP | 187 | $947K | 0.1% | $5064.17 | — | — | Put | 45337C952 |
| — | TRANSCEPT PHARMACEUTICALS INC | 281,330 | $945K | 0.1% | $3.36 | $3.15 | — | COM | 89354M106 |
| — | ACELRX PHARMACEUTICALS INC | 79,833 | $903K | 0.1% | $11.31 | $10.77 | — | COM | 00444T100 |
| — | ZOGENIX INC | 256,500 | $882K | 0.1% | $3.44 | $3.44 | — | COM | 98978L105 |
| — | OXIGENE INC | 345,658 | $871K | 0.1% | $2.52 | $2.52 | — | COM | 691828404 |
| — | THERAVANCE INC | 227 | $809K | 0.1% | $3563.88 | — | — | Call | 88338T904 |
| — | OCERA THERAPEUTICS INC | 59,984 | $779K | 0.0% | $12.99 | $12.99 | — | COM | 67552A108 |
| — | PHARMACYCLICS INC | 73 | $772K | 0.0% | $10575.34 | — | — | Put | 716933956 |
| — | KERYX BIOPHARMACEUTICALS | 592 | $767K | 0.0% | $1295.61 | — | — | Put | 492515951 |
| — | IDENIX PHARMACEUTICALS INC | 1,273 | $761K | 0.0% | $597.80 | — | — | Call | 45166R904 |
| — | SYNERGY PHARMACEUTICALS-CW16 | 349,217 | $751K | 0.0% | $2.15 | $2.15 | — | WAR | 871639118 |
| — | GALENA BIOPHARMA INC | 1,430 | $709K | 0.0% | $495.80 | — | — | Call | 363256908 |
| — | INFINITY PHARMACEUTICALS INC | 508 | $702K | 0.0% | $1381.89 | — | — | Call | 45665G903 |
| — | CONATUS PHARMACEUTICALS INC | 105,860 | $683K | 0.0% | $6.45 | $9.57 | — | COM | 20600T108 |
| — | NORTHWEST BIOTHERAPEUTICS INC | 1,812 | $683K | 0.0% | $376.93 | — | — | Put | 66737P950 |
| — | SUNESIS PHARMACEUTICALS INC | 1,418 | $672K | 0.0% | $473.91 | — | — | Call | 867328901 |
| — | GEVO INC | 463,552 | $663K | 0.0% | $1.43 | $1.43 | — | COM | 374396109 |
| — | AMBIT BIOSCIENCES CORP | 65,000 | $627K | 0.0% | $9.65 | $9.65 | — | COM | 02318X100 |
| — | BIOCRYST PHARMACEUTICALS INC | 792 | $602K | 0.0% | $760.10 | — | — | Put | 09058V953 |
| — | ENDOCYTE INC | 55,849 | $597K | 0.0% | $10.69 | $10.69 | — | COM | 29269A102 |
| — | AMARIN CORPORATION PLC | 2,986 | $588K | 0.0% | $196.92 | — | — | Call | 023111906 |
| — | ACELRX PHARMACEUTICALS INC | 513 | $580K | 0.0% | $1130.60 | — | — | Call | 00444T900 |
| — | AVANIR PHARMACEUTICALS INC | 1,663 | $559K | 0.0% | $336.14 | — | — | Call | 05348P901 |
| — | SUNESIS PHARMACEUTICALS INC | 111,847 | $530K | 0.0% | $4.74 | $4.74 | — | COM | 867328601 |
| — | ISIS PHARMACEUTICALS INC | 13,157 | $524K | 0.0% | $39.83 | $37.81 | — | COM | 464330109 |
| — | ISIS PHARMACEUTICALS INC | 130 | $518K | 0.0% | $3984.62 | — | — | Call | 464330909 |
| PRTA | PROTHENA CORP PLC | 19,000 | $504K | 0.0% | $26.53 * | $25.08 | 0.0% | SHS | G72800108 |
| — | ACHILLION PHARMACEUTICALS INC | 1,491 | $495K | 0.0% | $331.99 | — | — | Put | 00448Q951 |
| — | REPROS THERAPEUTICS INC | 265 | $485K | 0.0% | $1830.19 | — | — | Call | 76028H909 |
| — | GLAXOSMITHKLINE PLC | 88 | $470K | 0.0% | $5340.91 | — | — | Put | 37733W955 |
| EXAS | EXACT SCIENCES CORP | 39,729 | $464K | 0.0% | $11.68 | $11.47 | 0.0% | COM | 30063P105 |
| — | DENDREON CORP | 1,436 | $429K | 0.0% | $298.75 | — | — | Put | 24823Q957 |
| — | IMMUNOCELLULAR THERAPEUTICS LTD | 3,737 | $426K | 0.0% | $114.00 | — | — | Put | 452536955 |
| — | TWITTER INC | 62 | $395K | 0.0% | $6370.97 | — | — | Put | 90184L952 |
| — | DENDREON CORP | 131,500 | $393K | 0.0% | $2.99 | $2.95 | — | COM | 24823Q107 |
| — | AVANIR PHARMACEUTICALS INC | 113,308 | $381K | 0.0% | $3.36 | $4.09 | — | COM | 05348P401 |
| — | CHELSEA THERAPEUTICS INTERNATIONAL LTD | 83,200 | $369K | 0.0% | $4.44 | $4.44 | — | COM | 163428105 |
| — | FIBROCELL SCIENCE INC | 89,500 | $363K | 0.0% | $4.06 | $4.38 | — | COM | 315721209 |
| — | SUNESIS PHARMACEUTICALS INC | 760 | $360K | 0.0% | $473.68 | — | — | Put | 867328951 |
| — | KALOBIOS PHARMACEUTICALS INC | 80,650 | $356K | 0.0% | $4.41 | $4.52 | — | COM | 48344T100 |
| — | PLURISTEM THERAPEUTICS INC | 1,003 | $353K | 0.0% | $351.94 | — | — | Put | 72940R952 |
| — | VIVUS INC | 377 | $342K | 0.0% | $907.16 | — | — | Call | 928551900 |
| — | PRANA BIOTECHNOLOGY LTD | 458 | $321K | 0.0% | $700.87 | — | — | Call | 739727905 |
| — | STAAR SURGICAL CO | 194 | $314K | 0.0% | $1618.56 | — | — | Put | 852312955 |
| — | ISORAY INC | 621,526 | $311K | 0.0% | $0.50 | $0.65 | — | COM | 46489V104 |
| — | PHARMACYCLICS INC | 2,860 | $303K | 0.0% | $105.94 | $138.38 | — | COM | 716933106 |
| — | NUPATHE INC | 89,751 | $293K | 0.0% | $3.26 | $3.26 | — | COM | 67059M100 |
| — | WELLCARE HEALTH PLANS INC | 40 | $282K | 0.0% | $7050.00 | — | — | Put | 94946T956 |
| — | APRICUS BIOSCIENCES INC | 1,060 | $281K | 0.0% | $265.09 | — | — | Put | 03832V959 |
| — | ADVAXIS INC-CW18 | 162,375 | $276K | 0.0% | $1.70 | $1.70 | — | WAR | 007624117 |
| — | AMPIO PHARMACEUTICALS INC | 386 | $275K | 0.0% | $712.44 | — | — | Put | 03209T959 |
| — | REGENERON PHARMACEUTICALS INC | 10 | $275K | 0.0% | $27500.00 | — | — | Put | 75886F957 |
| TGTX | TG THERAPEUTICS INC | 66,000 | $257K | 0.0% | $3.89 * | $6.12 | -33.9% | COM | 88322Q108 |
| — | MOMENTA PHARMACEUTICALS INC | 132 | $233K | 0.0% | $1765.15 | — | — | Put | 60877T950 |
| — | ONCOGENEX PHARMACEUTICAL INC | 277 | $231K | 0.0% | $833.94 | — | — | Call | 68230A906 |
| — | MEI PHARMA INC | 270 | $216K | 0.0% | $800.00 | — | — | Call | 55279B902 |
| — | EXELIXIS INC | 349 | $214K | 0.0% | $613.18 | — | — | Put | 30161Q954 |
| — | CLOVIS ONCOLOGY INC | 34 | $205K | 0.0% | $6029.41 | — | — | Call | 189464900 |
| — | AMARIN CORPORATION PLC | 103,800 | $204K | 0.0% | $1.97 | $5.80 | — | ADR | 023111206 |
| — | MIRATI THERAPEUTICS INC | 12,213 | $203K | 0.0% | $16.62 | $16.62 | — | COM | 60468T105 |
| — | TARGACEPT INC | 451 | $187K | 0.0% | $414.63 | — | — | Call | 87611R906 |
| — | NEKTAR THERAPEUTICS | 160 | $182K | 0.0% | $1137.50 | — | — | Put | 640268958 |
| — | DYAX CORP | 238 | $179K | 0.0% | $752.10 | — | — | Call | 26746E903 |
| — | AMPIO PHARMACEUTICALS INC | 22,758 | $162K | 0.0% | $7.12 | $7.12 | — | COM | 03209T109 |
| — | PROGENICS PHARMACEUTICALS INC | 298 | $159K | 0.0% | $533.56 | — | — | Put | 743187956 |
| — | NOVAVAX INC | 30,000 | $154K | 0.0% | $5.13 | $3.16 | — | COM | 670002104 |
| — | TARGACEPT INC | 35,761 | $148K | 0.0% | $4.14 | $4.14 | — | COM | 87611R306 |
| — | CYTOKINETICS INC | 212 | $138K | 0.0% | $650.94 | — | — | Call | 23282W905 |
| GERN | GERON CORP | 28,013 | $133K | 0.0% | $4.75 * | $1.64 | +161.9% | COM | 374163103 |
| — | ONCOTHYREON INC | 679 | $120K | 0.0% | $176.73 | — | — | Call | 682324908 |
| — | ATHERSYS INC | 477 | $119K | 0.0% | $249.48 | — | — | Put | 04744L956 |
| — | TROVAGENE INC | 20,000 | $115K | 0.0% | $5.75 | $5.75 | — | COM | 897238309 |
| — | ENDOCYTE INC | 107 | $114K | 0.0% | $1065.42 | — | — | Call | 29269A902 |
| — | ONCOGENEX PHARMACEUTICAL INC | 126 | $105K | 0.0% | $833.33 | — | — | Put | 68230A956 |
| — | ANTHERA PHARMACEUTICALS INC | 307 | $94,000 | 0.0% | $306.19 | — | — | Call | 03674U901 |
| — | ATHERSYS INC | 354 | $89,000 | 0.0% | $251.41 | — | — | Call | 04744L906 |
| — | HORIZON PHARMA INC | 111 | $85,000 | 0.0% | $765.77 | — | — | Put | 44047T959 |
| — | AGENUS INC | 301 | $79,000 | 0.0% | $262.46 | — | — | Call | 00847G905 |
| — | CYTRX CORP | 125 | $78,000 | 0.0% | $624.00 | — | — | Call | 232828509 |
| — | SEQUENOM INC | 293 | $69,000 | 0.0% | $235.49 | — | — | Call | 817337905 |
| — | OREXIGEN THERAPEUTICS INC | 120 | $68,000 | 0.0% | $566.67 | — | — | Put | 686164954 |
| — | VENTRUS BIOSCIENCES INC | 160 | $61,000 | 0.0% | $381.25 | — | — | Put | 922822951 |
| — | PROSENSA HOLDING N.V. | 120 | $56,000 | 0.0% | $466.67 | — | — | Put | N71546950 |
| — | SEQUENOM INC | 205 | $48,000 | 0.0% | $234.15 | — | — | Put | 817337955 |
| — | SEQUENOM INC | 20,500 | $48,000 | 0.0% | $2.34 | $2.58 | — | COM | 817337405 |
| — | NORTHWEST BIOTHERAPEUTICS INC | 118 | $44,000 | 0.0% | $372.88 | — | — | Call | 66737P900 |
| — | AMARIN CORPORATION PLC | 193 | $38,000 | 0.0% | $196.89 | — | — | Put | 023111956 |
| — | APRICUS BIOSCIENCES INC | 10,638 | $28,000 | 0.0% | $2.63 | $2.63 | — | COM | 03832V109 |
| ANIP | ANI PHARMACEUTICALS INC | 1,219 | $24,000 | 0.0% | $19.69 * | $12.97 | 0.0% | COM | 00182C103 |
| — | IMMUNOCELLULAR THERAPEUTICS LTD | 25,000 | $23,000 | 0.0% | $0.92 | $0.92 | — | COM | 452536105 |
| — | DISCOVERY LABORATORIES INC | 100 | $23,000 | 0.0% | $230.00 | — | — | Call | 254668903 |
| — | NEKTAR THERAPEUTICS | 500 | $6,000 | 0.0% | $12.00 | $12.00 | — | COM | 640268108 |