Location: Miami Beach, FL
CIK: 0001535610 · Show all filings
Period: Q1 2014 (← Previous) (Next →)
Filing Date: May 14, 2014
Total Value: $1.784B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | VERTEX PHARMACEUTICALS INC | 24,000 | $170M | 9.5% | $7072.00 | — | — | Call | 92532F900 |
| — | TEVA PHARMACEUTICAL INDUSTRIES LTD | 23,433 | $124M | 6.9% | $5284.00 | — | — | Put | 881624959 |
| — | BRISTOL MYERS SQUIBB CO | 16,671 | $86.61M | 4.9% | $5195.01 | — | — | Call | 110122908 |
| — | TEVA PHARMACEUTICAL INDUSTRIES LTD | 15,192 | $80.28M | 4.5% | $5284.03 | — | — | Call | 881624909 |
| — | GILEAD SCIENCES INC | 11,166 | $79.12M | 4.4% | $7085.98 | — | — | Put | 375558953 |
| — | ACADIA PHARMACEUTICALS INC | 26,687 | $64.93M | 3.6% | $2432.98 | — | — | Call | 004225908 |
| — | BIOGEN IDEC INC | 2,075 | $63.47M | 3.6% | $30586.99 | — | — | Call | 09062X903 |
| — | ALLERGAN INC | 3,554 | $44.1M | 2.5% | $12409.96 | — | — | Call | 018490902 |
| — | VERTEX PHARMACEUTICALS INC | 5,926 | $41.91M | 2.3% | $7072.06 | — | — | Put | 92532F950 |
| — | MERCK & CO INC | 6,994 | $39.7M | 2.2% | $5677.01 | — | — | Put | 58933Y955 |
| — | REGENERON PHARMACEUTICALS | 1,299 | $39.01M | 2.2% | $30027.71 | — | — | Put | 75886F957 |
| — | ABBVIE INC | 7,535 | $38.73M | 2.2% | $5140.01 | — | — | Call | 00287Y909 |
| — | REGENERON PHARMACEUTICALS | 1,216 | $36.51M | 2.0% | $30027.96 | — | — | Call | 75886F907 |
| — | APPLE INC | 579 | $31.08M | 1.7% | $53673.58 | — | — | Put | 037833950 |
| — | APPLE INC | 579 | $31.08M | 1.7% | $53673.58 | — | — | Call | 037833900 |
| — | SPDR SERIES TRUST | 2,006 | $28.58M | 1.6% | $14247.76 | — | — | Put | 78464A950 |
| — | CELGENE CORP | 2,044 | $28.53M | 1.6% | $13959.88 | — | — | Put | 151020954 |
| SPY | SPDR S&P 500 ETF TR | 1,338 | $25.03M | 1.4% | $18704.04 | — | — | Put | 78462F103 |
| — | INTERMUNE INC | 6,624 | $22.17M | 1.2% | $3347.07 | — | — | Call | 45884X903 |
| — | OPKO HEALTH INC | 23,227 | $21.65M | 1.2% | $932.02 | — | — | Put | 68375N953 |
| — | GILEAD SCIENCES INC | 2,993 | $21.21M | 1.2% | $7085.87 | — | — | Call | 375558903 |
| TEVA | TEVA PHARMACEUTICAL INDUSTRIES LTD | 364,741 | $19.27M | 1.1% | $52.84 | $40.00 | — | ADR | 881624209 |
| — | OPKO HEALTH INC | 20,102 | $18.73M | 1.1% | $932.00 | — | — | Call | 68375N903 |
| — | SANGAMO BIOSCIENCES INC | 10,010 | $18.1M | 1.0% | $1807.99 | — | — | Call | 800677906 |
| — | SEATTLE GENETICS INC | 3,711 | $16.91M | 0.9% | $4555.91 | — | — | Call | 812578902 |
| — | SEATTLE GENETICS INC | 3,497 | $15.93M | 0.9% | $4555.91 | — | — | Put | 812578952 |
| — | INTERMUNE INC | 4,681 | $15.67M | 0.9% | $3346.93 | — | — | Put | 45884X953 |
| — | PHARMACYCLICS INC | 1,529 | $15.32M | 0.9% | $10022.24 | — | — | Put | 716933956 |
| — | ABBVIE INC | 2,979 | $15.31M | 0.9% | $5139.98 | — | — | Put | 00287Y959 |
| — | PHARMACYCLICS INC | 1,500 | $15.03M | 0.8% | $10022.00 | — | — | Call | 716933906 |
| — | AMGEN INC | 1,138 | $14.04M | 0.8% | $12333.92 | — | — | Put | 031162950 |
| — | PFIZER INC | 4,301 | $13.81M | 0.8% | $3212.04 | — | — | Call | 717081903 |
| — | CLOVIS ONCOLOGY INC | 1,931 | $13.38M | 0.7% | $6926.98 | — | — | Call | 189464900 |
| — | THERMO FISHER SCIENTIFIC INC | 1,100 | $13.23M | 0.7% | $12023.64 | — | — | Call | 883556902 |
| — | OXYGEN BIOTHERAPEUTICS INC | 2,120,754 | $11.77M | 0.7% | $5.55 | $5.55 | — | COM | 69207P308 |
| — | MERCK & CO INC | 2,016 | $11.45M | 0.6% | $5677.08 | — | — | Call | 58933Y905 |
| ACAD | ACADIA PHARMACEUTICALS INC | 463,146 | $11.27M | 0.6% | $24.33 * | $16.07 | +57.4% | COM | 004225108 |
| — | SYNAGEVA BIOPHARMA CORP | 1,331 | $11.04M | 0.6% | $8296.77 | — | — | Put | 87159A953 |
| GILD | GILEAD SCIENCES INC | 155,073 | $10.99M | 0.6% | $70.86 * | $45.30 | +20.3% | COM | 375558103 |
| — | AUXILIUM PHARMACEUTICALS INC | 3,983 | $10.83M | 0.6% | $2718.05 | — | — | Call | 05334D907 |
| — | ALLERGAN INC | 863 | $10.71M | 0.6% | $12410.20 | — | — | Put | 018490952 |
| IWM | ISHARES | 890 | $10.35M | 0.6% | $11633.71 | — | — | Put | 464287655 |
| — | ELI LILLY | 1,719 | $10.12M | 0.6% | $5885.98 | — | — | Call | 532457908 |
| — | SAREPTA THERAPEUTICS INC | 4,060 | $9.756M | 0.5% | $2402.96 | — | — | Put | 803607950 |
| — | ISIS PHARMACEUTICALS INC | 2,078 | $8.979M | 0.5% | $4320.98 | — | — | Put | 464330959 |
| — | KERYX BIOPHARMACEUTICALS | 5,238 | $8.926M | 0.5% | $1704.09 | — | — | Put | 492515951 |
| — | BIO PATH HOLDINGS INC | 3,313,600 | $8.781M | 0.5% | $2.65 | $2.65 | — | COM | 09057N102 |
| — | MANNKIND CORP | 21,110 | $8.486M | 0.5% | $401.99 | — | — | Put | 56400P951 |
| SRPT | SAREPTA THERAPEUTICS INC | 352,100 | $8.461M | 0.5% | $24.03 * | $36.12 | -29.4% | COM | 803607100 |
| OPK | OPKO HEALTH INC | 831,237 | $7.747M | 0.4% | $9.32 * | $8.77 | 0.0% | COM | 68375N103 |
| — | ROCKWELL MEDICAL INC | 5,652 | $7.155M | 0.4% | $1265.92 | — | — | Put | 774374952 |
| — | CLOVIS ONCOLOGY INC | 1,000 | $6.927M | 0.4% | $6927.00 | — | — | Put | 189464950 |
| — | ISIS PHARMACEUTICALS INC | 1,584 | $6.844M | 0.4% | $4320.71 | — | — | Call | 464330909 |
| XBI | SPDR SERIES TRUST | 43,745 | $6.233M | 0.3% | $142.48 | $142.48 | — | TR | 78464A870 |
| — | PEREGRINE PHARMACEUTICALS INC | 238,409 | $6.017M | 0.3% | $25.24 | $25.24 | — | COM | 713661304 |
| — | REPROS THERAPEUTICS INC | 3,371 | $5.98M | 0.3% | $1773.95 | — | — | Put | 76028H959 |
| — | ARIAD PHARMACEUTICALS INC | 7,220 | $5.819M | 0.3% | $805.96 | — | — | Call | 04033A900 |
| — | INTEROIL CORP | 895 | $5.796M | 0.3% | $6475.98 | — | — | Put | 460951956 |
| — | INCYTE CORP | 1,046 | $5.598M | 0.3% | $5351.82 | — | — | Call | 45337C902 |
| QURE | UNIQURE B.V. | 354,000 | $5.505M | 0.3% | $15.55 * | $15.95 | 0.0% | SHS | N90064101 |
| — | PUMA BIOTECHNOLOGY INC | 512 | $5.332M | 0.3% | $10414.06 | — | — | Call | 74587V907 |
| AMGN | AMGEN INC | 42,311 | $5.219M | 0.3% | $123.35 * | $86.89 | 0.0% | COM | 031162100 |
| REGN | REGENERON PHARMACEUTICALS | 17,191 | $5.162M | 0.3% | $300.27 * | $306.39 | 0.0% | COM | 75886F107 |
| — | ACHILLION PHARMACEUTICALS INC | 14,693 | $4.834M | 0.3% | $329.00 | — | — | Call | 00448Q901 |
| — | ARIAD PHARMACEUTICALS INC | 5,981 | $4.821M | 0.3% | $806.05 | — | — | Put | 04033A950 |
| — | UNITED THERAPEUTICS CORP | 510 | $4.796M | 0.3% | $9403.92 | — | — | Call | 91307C902 |
| — | NEWLINK GENETICS CORP | 1,676 | $4.76M | 0.3% | $2840.10 | — | — | Call | 651511907 |
| — | CEMPRA INC | 405,946 | $4.689M | 0.3% | $11.55 | $10.37 | — | COM | 15130J109 |
| TMO | THERMO FISHER SCIENTIFIC INC | 38,630 | $4.645M | 0.3% | $120.24 * | $114.47 | 0.0% | COM | 883556102 |
| — | CUBIST PHARMACEUTICALS INC | 603 | $4.411M | 0.2% | $7315.09 | — | — | Put | 229678957 |
| — | CELSUS THERAPEUTICS-SPON ADR | 669,080 | $4.342M | 0.2% | $6.49 | $6.49 | — | ADR | 15119A202 |
| — | BIOLINERX LTD-SPONS ADR | 1,902,800 | $4.243M | 0.2% | $2.23 | $2.23 | — | ADR | 09071M106 |
| MGNX | MACROGENICS INC | 150,553 | $4.19M | 0.2% | $27.83 * | $35.31 | 0.0% | COM | 556099109 |
| — | ARROWHEAD RESEARCH CORP | 2,478 | $4.069M | 0.2% | $1642.05 | — | — | Put | 042797959 |
| — | ALIMERA SCIENCES INC | 500,000 | $3.945M | 0.2% | $7.89 | $7.89 | — | COM | 016259103 |
| — | NOVAVAX INC | 7,935 | $3.595M | 0.2% | $453.06 | — | — | Put | 670002954 |
| — | PLURISTEM THERAPEUTICS INC | 9,603 | $3.553M | 0.2% | $369.99 | — | — | Put | 72940R952 |
| — | EPIZYME INC | 151,220 | $3.443M | 0.2% | $22.77 | $22.77 | — | COM | 29428V104 |
| — | BIODELIVERY SCIENCES INTERNATIONAL INC | 3,952 | $3.335M | 0.2% | $843.88 | — | — | Put | 09060J956 |
| SGMO | SANGAMO BIOSCIENCES INC | 177,265 | $3.205M | 0.2% | $18.08 * | $19.28 | 0.0% | COM | 800677106 |
| — | OVASCIENCE INC | 357,354 | $3.195M | 0.2% | $8.94 | $9.35 | — | COM | 69014Q101 |
| — | GALENA BIOPHARMA INC | 11,782 | $2.946M | 0.2% | $250.04 | — | — | Put | 363256958 |
| — | TESARO INC | 98,500 | $2.904M | 0.2% | $29.48 | $29.48 | — | COM | 881569107 |
| — | TONIX PHARMACEUTICALS HOLDIN | 275,000 | $2.863M | 0.2% | $10.41 | $10.41 | — | COM | 890260201 |
| — | KERYX BIOPHARMACEUTICALS | 167,999 | $2.863M | 0.2% | $17.04 | $17.04 | — | COM | 492515101 |
| — | IGNYTA INC | 341,810 | $2.837M | 0.2% | $8.30 | $8.30 | — | COM | 451731103 |
| — | LIGAND PHARMACEUTICALS INC | 420 | $2.825M | 0.2% | $6726.19 | — | — | Call | 53220K904 |
| — | PUMA BIOTECHNOLOGY INC | 271 | $2.822M | 0.2% | $10413.28 | — | — | Put | 74587V957 |
| — | ACELRX PHARMACEUTICALS INC | 2,322 | $2.789M | 0.2% | $1201.12 | — | — | Put | 00444T950 |
| — | ENDOCYTE INC | 1,170 | $2.786M | 0.2% | $2381.20 | — | — | Put | 29269A952 |
| — | MEDIVATION INC | 430 | $2.768M | 0.2% | $6437.21 | — | — | Call | 58501N901 |
| — | INTEROIL CORP | 42,361 | $2.743M | 0.2% | $64.75 | $64.75 | — | COM | 460951106 |
| — | CELGENE CORP | 19,499 | $2.722M | 0.2% | $139.60 | $139.60 | — | COM | 151020104 |
| — | CEL-SCI CORP-W | 6,316,000 | $2.684M | 0.2% | $0.42 | $0.42 | — | WAR | 150837177 |
| — | CELSION CORP | 7,565 | $2.549M | 0.1% | $336.95 | — | — | Put | 15117N954 |
| — | INSMED INC | 1,302 | $2.479M | 0.1% | $1903.99 | — | — | Call | 457669907 |
| — | AMARIN CORPORATION PLC -ADR | 1,321,622 | $2.392M | 0.1% | $1.81 | $2.12 | — | ADR | 023111206 |
| — | MELA SCIENCES INC | 3,724,475 | $2.32M | 0.1% | $0.62 | $0.64 | — | COM | 55277R100 |
| — | BLUEBIRD BIO INC | 101,786 | $2.315M | 0.1% | $22.74 | $20.98 | — | COM | 09609G100 |
| — | ANTHERA PHARMACEUTICALS INC | 688,037 | $2.305M | 0.1% | $3.35 | $4.02 | — | COM | 03674U201 |
| — | PROGENICS PHARMACEUTICALS | 517,794 | $2.118M | 0.1% | $4.09 | $4.09 | — | COM | 743187106 |
| — | NEUROCRINE BIOSCIENCES INC | 1,307 | $2.104M | 0.1% | $1609.79 | — | — | Call | 64125C909 |
| — | PFIZER INC | 650 | $2.088M | 0.1% | $3212.31 | — | — | Put | 717081953 |
| — | SUNESIS PHARMACEUTICALS INC | 3,139 | $2.075M | 0.1% | $661.04 | — | — | Call | 867328901 |
| — | DYAX CORP | 230,000 | $2.065M | 0.1% | $8.98 | $7.83 | — | COM | 26746E103 |
| — | UNITED THERAPEUTICS CORP | 217 | $2.04M | 0.1% | $9400.92 | — | — | Put | 91307C952 |
| — | CELATOR PHARMACEUTICALS INC | 626,077 | $2.022M | 0.1% | $3.23 | $3.21 | — | COM | 15089R102 |
| — | MOMENTA PHARMACEUTICALS INC | 1,729 | $2.014M | 0.1% | $1164.84 | — | — | Call | 60877T900 |
| — | ENTREMED INC | 1,065,217 | $1.949M | 0.1% | $1.83 | $1.99 | — | COM | 29382F202 |
| — | AVANIR PHARMACEUTICALS INC | 5,000 | $1.835M | 0.1% | $367.00 | — | — | Call | 05348P901 |
| — | NEKTAR THERAPEUTICS | 1,461 | $1.771M | 0.1% | $1212.18 | — | — | Put | 640268958 |
| — | GALENA BIOPHARMA INC | 708,089 | $1.77M | 0.1% | $2.50 | $2.50 | — | COM | 363256108 |
| — | ARENA PHARMACEUTICALS INC | 2,756 | $1.736M | 0.1% | $629.90 | — | — | Put | 040047952 |
| — | ARROWHEAD RESEARCH CORP | 1,027 | $1.686M | 0.1% | $1641.67 | — | — | Call | 042797909 |
| SMLR | SEMLER SCIENTIFIC INC | 318,198 | $1.664M | 0.1% | $5.23 * | $6.25 | 0.0% | COM | 81684M104 |
| — | THERAVANCE INC | 537 | $1.661M | 0.1% | $3093.11 | — | — | Put | 88338T954 |
| — | RECRO PHARMA INC | 227,793 | $1.647M | 0.1% | $7.23 | $7.23 | — | COM | 75629F109 |
| — | AEGERION PHARMACEUTICALS INC | 34,420 | $1.587M | 0.1% | $46.11 | $63.34 | — | COM | 00767E102 |
| — | SALIX PHARMACEUTICALS LTD | 148 | $1.533M | 0.1% | $10358.11 | — | — | Put | 795435956 |
| — | BIOGEN IDEC INC | 50 | $1.529M | 0.1% | $30580.00 | — | — | Put | 09062X953 |
| EXEL | EXELIXIS INC | 429,000 | $1.519M | 0.1% | $3.54 * | $6.81 | 0.0% | COM | 30161Q104 |
| — | CERES INC | 1,695,700 | $1.488M | 0.1% | $0.88 | $0.88 | — | COM | 156773103 |
| — | DICERNA PHARMACEUTICALS INC | 51,510 | $1.455M | 0.1% | $28.25 | $28.25 | — | COM | 253031108 |
| — | OPHTHOTECH CORP | 400 | $1.43M | 0.1% | $3575.00 | — | — | Put | 683745953 |
| — | AVANIR PHARMACEUTICALS INC | 3,750 | $1.376M | 0.1% | $366.93 | — | — | Put | 05348P951 |
| — | ARENA PHARMACEUTICALS INC | 215,700 | $1.359M | 0.1% | $6.30 | $6.30 | — | COM | 040047102 |
| — | COMPUGEN LTD | 1,287 | $1.353M | 0.1% | $1051.28 | — | — | Call | M25722905 |
| — | FURIEX PHARMACEUTICALS INC | 152 | $1.322M | 0.1% | $8697.37 | — | — | Call | 36106P901 |
| — | CLEVELAND BIOLABS INC | 1,826,158 | $1.244M | 0.1% | $0.68 | $0.68 | — | COM | 185860103 |
| — | CUBIST PHARMACEUTICALS INC | 16,590 | $1.214M | 0.1% | $73.18 | $73.18 | — | COM | 229678107 |
| — | NOVAVAX INC | 251,500 | $1.139M | 0.1% | $4.53 | $4.37 | — | COM | 670002104 |
| — | SYNAGEVA BIOPHARMA CORP | 13,538 | $1.123M | 0.1% | $82.95 | $82.95 | — | COM | 87159A103 |
| — | THERAVANCE INC | 34,531 | $1.068M | 0.1% | $30.93 | $30.93 | — | COM | 88338T104 |
| — | AMPIO PHARMACEUTICALS INC | 1,676 | $1.064M | 0.1% | $634.84 | — | — | Put | 03209T959 |
| — | MANNKIND CORP | 2,536 | $1.019M | 0.1% | $401.81 | — | — | Call | 56400P901 |
| — | TEKMIRA PHARMACEUTICALS CORP | 450 | $967K | 0.1% | $2148.89 | — | — | Call | 87911B909 |
| — | MEDGENICS INC | 817,050 | $940K | 0.1% | $1.15 | $1.15 | — | WAR | 58436Q112 |
| — | PLURISTEM THERAPEUTICS INC | 253,383 | $938K | 0.1% | $3.70 | $3.70 | — | COM | 72940R102 |
| — | EXACT SCIENCES CORP | 655 | $928K | 0.1% | $1416.79 | — | — | Put | 30063P955 |
| — | ALEXZA PHARMACEUTICALS INC SHS | 2,040 | $904K | 0.1% | $443.14 | — | — | Call | 015384909 |
| — | CESCA THERAPEUTICS INC | 529,298 | $900K | 0.1% | $1.70 | $1.70 | — | COM | 157131103 |
| — | OREXIGEN THERAPEUTICS INC | 1,379 | $896K | 0.1% | $649.75 | — | — | Put | 686164954 |
| — | BRISTOL MYERS SQUIBB CO | 172 | $894K | 0.1% | $5197.67 | — | — | Put | 110122958 |
| — | PROTHENA CORPORATION PLC | 225 | $862K | 0.0% | $3831.11 | — | — | Call | G72800908 |
| — | XOMA CORP | 164,728 | $858K | 0.0% | $5.21 | $4.48 | — | COM | 98419J107 |
| — | AVEO PHARMACEUTICALS INC | 573,416 | $857K | 0.0% | $1.49 | $1.84 | — | COM | 053588109 |
| — | SAREPTA THERAPEUTICS INC | 351 | $843K | 0.0% | $2401.71 | — | — | Call | 803607900 |
| — | PRANA BIOTECHNOLOGY LTD | 2,994 | $838K | 0.0% | $279.89 | — | — | Call | 739727905 |
| — | ALIMERA SCIENCES INC | 1,039 | $820K | 0.0% | $789.22 | — | — | Put | 016259953 |
| — | ACADIA PHARMACEUTICALS INC | 333 | $810K | 0.0% | $2432.43 | — | — | Put | 004225958 |
| — | PACIFIC ETHANOL INC | 512 | $797K | 0.0% | $1556.64 | — | — | Put | 69423U955 |
| — | IDENIX PHARMACEUTICALS INC | 1,302 | $785K | 0.0% | $602.92 | — | — | Call | 45166R904 |
| — | CELSION CORP | 227,156 | $766K | 0.0% | $3.37 | $3.37 | — | COM | 15117N404 |
| EXAS | EXACT SCIENCES CORP | 54,000 | $765K | 0.0% | $14.17 * | $12.01 | +12.5% | COM | 30063P105 |
| — | ALKERMES PLC | 173 | $763K | 0.0% | $4410.40 | — | — | Call | G01767905 |
| — | EXELIXIS INC | 2,129 | $754K | 0.0% | $354.16 | — | — | Call | 30161Q904 |
| — | SYNERGY PHARMACEUTICALS | 377,908 | $718K | 0.0% | $1.90 | $1.90 | — | WAR | 871639308 |
| — | ALKERMES PLC | 155 | $683K | 0.0% | $4406.45 | — | — | Put | G01767955 |
| — | DISCOVERY LABORATORIES INC | 311,673 | $670K | 0.0% | $2.15 | $2.25 | — | COM | 254668403 |
| — | ZIOPHARM ONCOLOGY INC | 1,457 | $667K | 0.0% | $457.79 | — | — | Put | 98973P951 |
| — | ONCOGENEX PHARMACEUTICALS INC | 545 | $641K | 0.0% | $1176.15 | — | — | Call | 68230A906 |
| — | OCERA THERAPEUTICS INC | 60,726 | $641K | 0.0% | $10.56 | $12.96 | — | COM | 67552A108 |
| — | NORTHWEST BIOTHERAPEUTICS INC | 868 | $628K | 0.0% | $723.50 | — | — | Put | 66737P950 |
| — | CYTOKINETICS INC | 661 | $628K | 0.0% | $950.08 | — | — | Call | 23282W905 |
| — | FURIEX PHARMACEUTICALS INC | 7,180 | $625K | 0.0% | $87.05 | $87.05 | — | COM | 36106P101 |
| — | NEKTAR THERAPEUTICS | 50,177 | $608K | 0.0% | $12.12 | $12.12 | — | COM | 640268108 |
| — | AGENUS INC | 185,830 | $589K | 0.0% | $3.17 | $3.17 | — | COM | 00847G705 |
| — | INSMED INC | 305 | $581K | 0.0% | $1904.92 | — | — | Put | 457669957 |
| — | OPHTHOTECH CORP | 15,944 | $570K | 0.0% | $35.75 | $35.75 | — | COM | 683745103 |
| — | XOMA CORP | 1,082 | $564K | 0.0% | $521.26 | — | — | Put | 98419J957 |
| — | ACELRX PHARMACEUTICALS INC | 469 | $563K | 0.0% | $1200.43 | — | — | Call | 00444T900 |
| — | XOMA CORP | 1,073 | $559K | 0.0% | $520.97 | — | — | Call | 98419J907 |
| — | ACELRX PHARMACEUTICALS INC | 46,316 | $556K | 0.0% | $12.00 | $10.77 | — | COM | 00444T100 |
| — | SUNESIS PHARMACEUTICALS INC | 818 | $541K | 0.0% | $661.37 | — | — | Put | 867328951 |
| — | NEOSTEM INC | 763 | $538K | 0.0% | $705.11 | — | — | Put | 640650954 |
| — | MEDICINES CO | 184 | $523K | 0.0% | $2842.39 | — | — | Put | 584688955 |
| — | ZIOPHARM ONCOLOGY INC | 110,573 | $506K | 0.0% | $4.58 | $4.58 | — | COM | 98973P101 |
| — | ISORAY INC | 225,375 | $496K | 0.0% | $2.20 | $0.65 | — | COM | 46489V104 |
| — | PROTHENA CORPORATION PLC | 125 | $479K | 0.0% | $3832.00 | — | — | Put | G72800958 |
| — | AGENUS INC | 1,506 | $477K | 0.0% | $316.73 | — | — | Call | 00847G905 |
| — | NEWLINK GENETICS CORP | 166 | $472K | 0.0% | $2843.37 | — | — | Put | 651511957 |
| — | MOMENTA PHARMACEUTICALS INC | 382 | $445K | 0.0% | $1164.92 | — | — | Put | 60877T950 |
| — | EXELIXIS INC | 1,216 | $430K | 0.0% | $353.62 | — | — | Put | 30161Q954 |
| — | TESARO INC | 140 | $413K | 0.0% | $2950.00 | — | — | Call | 881569907 |
| — | ENANTA PHARMACEUTICALS INC | 102 | $408K | 0.0% | $4000.00 | — | — | Call | 29251M906 |
| — | NORTHWEST BIOTHERAPEUTICS INC | 551 | $399K | 0.0% | $724.14 | — | — | Call | 66737P900 |
| — | ADAMIS PHARMACEUTICALS CORP | 60,767 | $386K | 0.0% | $6.35 | $6.39 | — | COM | 00547W208 |
| — | ACHILLION PHARMACEUTICALS INC | 1,142 | $376K | 0.0% | $329.25 | — | — | Put | 00448Q951 |
| — | ENDOCYTE INC | 154 | $367K | 0.0% | $2383.12 | — | — | Call | 29269A902 |
| — | GALMED PHARMACEUTICALS LTD | 31,401 | $360K | 0.0% | $11.46 | $11.46 | — | SHS | M47238106 |
| — | GALENA BIOPHARMA INC | 1,400 | $350K | 0.0% | $250.00 | — | — | Call | 363256908 |
| — | ATHERSYS INC | 1,045 | $339K | 0.0% | $324.40 | — | — | Put | 04744L956 |
| — | HORIZON PHARMA INC | 219 | $331K | 0.0% | $1511.42 | — | — | Put | 44047T959 |
| — | PROGENICS PHARMACEUTICALS | 794 | $324K | 0.0% | $408.06 | — | — | Call | 743187906 |
| — | ZIOPHARM ONCOLOGY INC | 690 | $316K | 0.0% | $457.97 | — | — | Call | 98973P901 |
| — | ADVAXIS INC | 1,000 | $314K | 0.0% | $314.00 | — | — | Put | 007624958 |
| — | APRICUS BIOSCIENCES INC | 1,457 | $313K | 0.0% | $214.82 | — | — | Put | 03832V959 |
| — | DISCOVERY LABORATORIES INC | 1,414 | $304K | 0.0% | $214.99 | — | — | Call | 254668903 |
| — | IMMUNOCELLULAR THERAPEUTICS LTD | 2,405 | $293K | 0.0% | $121.83 | — | — | Put | 452536955 |
| — | OREXIGEN THERAPEUTICS INC | 44,784 | $291K | 0.0% | $6.50 | $6.50 | — | COM | 686164104 |
| — | PSIVIDA CORP | 640 | $262K | 0.0% | $409.38 | — | — | Put | 74440J951 |
| — | AMPIO PHARMACEUTICALS INC | 41,000 | $260K | 0.0% | $6.34 | $6.77 | — | COM | 03209T109 |
| OMER | OMEROS CORP | 20,000 | $241K | 0.0% | $12.05 | $12.28 | 0.0% | COM | 682143102 |
| ALKS | ALKERMES PLC | 5,126 | $226K | 0.0% | $44.09 * | $47.58 | 0.0% | SHS | G01767105 |
| — | SALIX PHARMACEUTICALS LTD | 2,170 | $225K | 0.0% | $103.69 | $103.69 | — | COM | 795435106 |
| — | MOMENTA PHARMACEUTICALS INC | 18,274 | $213K | 0.0% | $11.66 | $11.66 | — | COM | 60877T100 |
| — | ATHERSYS INC | 588 | $191K | 0.0% | $324.83 | — | — | Call | 04744L906 |
| — | ADVAXIS INC | 144,935 | $181K | 0.0% | $1.25 | $1.70 | — | WAR | 007624117 |
| — | CORCEPT THERAPEUTICS INC | 400 | $174K | 0.0% | $435.00 | — | — | Call | 218352902 |
| — | IDERA PHARMACEUTICALS INC | 398 | $162K | 0.0% | $407.04 | — | — | Call | 45168K906 |
| — | NEUROCRINE BIOSCIENCES INC | 100 | $161K | 0.0% | $1610.00 | — | — | Put | 64125C959 |
| — | OXYGEN BIOTHERAPEUTICS INC | 274 | $152K | 0.0% | $554.74 | — | — | Call | 69207P908 |
| — | ONCOTHYREON INC | 511 | $152K | 0.0% | $297.46 | — | — | Call | 682324908 |
| — | DYAX CORP | 163 | $146K | 0.0% | $895.71 | — | — | Call | 26746E903 |
| — | EDAP TMS SA -ADR | 500 | $143K | 0.0% | $286.00 | — | — | Call | 268311907 |
| — | CEMPRA INC | 121 | $140K | 0.0% | $1157.02 | — | — | Call | 15130J909 |
| — | VIVUS INC | 22,032 | $131K | 0.0% | $5.95 | $5.95 | — | COM | 928551100 |
| — | PROGENICS PHARMACEUTICALS | 298 | $122K | 0.0% | $409.40 | — | — | Put | 743187956 |
| — | TROVAGENE INC | 20,000 | $115K | 0.0% | $5.75 | $5.75 | — | COM | 897238309 |
| — | VIVUS INC | 189 | $112K | 0.0% | $592.59 | — | — | Put | 928551950 |
| — | ANTHERA PHARMACEUTICALS INC | 322 | $108K | 0.0% | $335.40 | — | — | Call | 03674U901 |
| — | DEPOMED INC | 551 | $103K | 0.0% | $186.93 | — | — | Call | 249908904 |
| — | AGENUS INC | 245 | $78,000 | 0.0% | $318.37 | — | — | Put | 00847G955 |
| EDAP | EDAP TMS SA -ADR | 23,200 | $66,000 | 0.0% | $2.84 | $2.72 | — | ADR | 268311107 |
| — | PRANA BIOTECHNOLOGY LTD | 222 | $62,000 | 0.0% | $279.28 | — | — | Put | 739727955 |
| — | IDERA PHARMACEUTICALS INC | 15,000 | $61,000 | 0.0% | $4.07 | $4.07 | — | COM | 45168K306 |
| — | BIODEL INC | 182 | $50,000 | 0.0% | $274.73 | — | — | Put | 09064M954 |
| — | PRANA BIOTECHNOLOGY LTD | 17,300 | $48,000 | 0.0% | $2.77 | $2.77 | — | ADR | 739727105 |
| — | PSIVIDA CORP | 100 | $41,000 | 0.0% | $410.00 | — | — | Call | 74440J901 |
| — | AMARIN CORPORATION PLC -ADR | 200 | $36,000 | 0.0% | $180.00 | — | — | Call | 023111906 |
| — | APRICUS BIOSCIENCES INC | 12,503 | $27,000 | 0.0% | $2.16 | $2.56 | — | COM | 03832V109 |
| — | CEL-SCI CORP | 12,888 | $20,000 | 0.0% | $1.55 | $0.59 | — | COM | 150837508 |