Location: Miami Beach, FL
CIK: 0001535610 · Show all filings
Period: Q4 2014 (← Previous) (Next →)
Filing Date: Feb 17, 2015
Total Value: $3.166B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | TESARO INC NOTE 3.00% | 6,000,000 | $748M | 23.6% | $124.63 | $176.19 | — | NOTE | 881569AA5 |
| — | DEPOMED INC 2.5% | 3,000,000 | $324M | 10.2% | $107.94 | $212.42 | — | NOTE | 249908AA2 |
| — | SPDR S&P 500 ETF TRUST UNIT | 7,588 | $156M | 4.9% | $20549.95 | — | — | Put | 78462F953 |
| — | BIOGEN IDEC INC | 4,580 | $155M | 4.9% | $33944.98 | — | — | Call | 09062X903 |
| — | BRISTOL MYERS SQUIBB CO | 24,763 | $146M | 4.6% | $5903.00 | — | — | Call | 110122908 |
| — | GILEAD SCIENCES INC | 12,185 | $115M | 3.6% | $9426.02 | — | — | Put | 375558953 |
| — | VERTEX PHARMACEUTICALS INC | 9,592 | $114M | 3.6% | $11880.00 | — | — | Put | 92532F950 |
| — | ACADIA PHARMACEUTICALS INC | 28,364 | $90.06M | 2.8% | $3175.01 | — | — | Call | 004225908 |
| — | ABBVIE INC | 12,792 | $83.71M | 2.6% | $6544.01 | — | — | Call | 00287Y909 |
| — | ISHARES RUSSELL 2000 | 5,494 | $65.75M | 2.1% | $11967.05 | — | — | Put | 464287955 |
| — | PFIZER INC | 20,812 | $64.83M | 2.0% | $3114.98 | — | — | Put | 717081953 |
| — | ACTAVIS PLC | 2,318 | $59.67M | 1.9% | $25741.16 | $232.69 | — | Call | G0083B108 |
| — | VERTEX PHARMACEUTICALS INC | 3,881 | $46.11M | 1.5% | $11879.93 | — | — | Call | 92532F900 |
| — | ELI LILLY & CO SHS | 6,405 | $44.19M | 1.4% | $6898.99 | — | — | Call | 532457908 |
| PFE | PFIZER INC | 1,254,894 | $39.09M | 1.2% | $31.15 * | $17.97 | 0.0% | COM | 717081103 |
| — | ALLERGAN INC | 1,500 | $31.89M | 1.0% | $21259.33 | — | — | Call | 018490902 |
| — | ASTRAZENECA PLC | 4,338 | $30.53M | 1.0% | $7038.04 | — | — | Put | 046353958 |
| ACAD | ACADIA PHARMACEUTICALS INC | 864,437 | $27.45M | 0.9% | $31.75 * | $28.36 | 0.0% | COM | 004225108 |
| — | ACTAVIS PLC | 1,006 | $25.89M | 0.8% | $25740.56 | — | — | Put | G0083B958 |
| — | UNITED THERAPEUTICS CORP | 1,981 | $25.65M | 0.8% | $12949.02 | — | — | Call | 91307C902 |
| — | PFIZER INC | 7,807 | $24.32M | 0.8% | $3115.02 | — | — | Call | 717081903 |
| — | INTEROIL CORP | 4,481 | $21.86M | 0.7% | $4879.04 | — | — | Put | 460951956 |
| — | OPKO HEALTH INC | 21,847 | $21.82M | 0.7% | $998.99 | — | — | Call | 68375N903 |
| — | COVIDIEN PLC | 1,911 | $19.55M | 0.6% | $10228.15 | — | — | Put | G2554F953 |
| — | ASTRAZENECA PLC | 2,503 | $17.62M | 0.6% | $7037.95 | — | — | Call | 046353908 |
| — | MERCK & CO. INC. | 3,028 | $17.2M | 0.5% | $5679.00 | — | — | Put | 58933Y955 |
| — | ACTAVIS PLC | 65,181 | $16.78M | 0.5% | $257.41 | $232.69 | — | SHS | G0083B108 |
| — | SANGAMO BIOSCIENCES INC | 10,168 | $15.47M | 0.5% | $1521.05 | — | — | Call | 800677906 |
| — | BRISTOL MYERS SQUIBB CO | 2,359 | $13.93M | 0.4% | $5902.92 | — | — | Put | 110122958 |
| — | AGILENT TECHNOLOGIES INC | 3,337 | $13.66M | 0.4% | $4094.10 | — | — | Call | 00846U901 |
| — | AUXILIUM PHARMACEUTICALS INC | 3,964 | $13.63M | 0.4% | $3438.45 | — | — | Call | 05334D907 |
| AZN | ASTRAZENECA PLC | 192,055 | $13.52M | 0.4% | $70.38 | $19.49 | — | ADR | 046353108 |
| — | INTEROIL CORP | 270,330 | $13.19M | 0.4% | $48.79 | $58.17 | — | COM | 460951106 |
| — | BLUEBIRD BIO INC | 1,377 | $12.63M | 0.4% | $9172.11 | — | — | Call | 09609G900 |
| — | ACHILLION PHARMACEUTICALS | 1,004,187 | $12.3M | 0.4% | $12.25 | $12.12 | — | COM | 00448Q201 |
| MRK | MERCK & CO. INC. | 211,130 | $11.99M | 0.4% | $56.79 * | $39.35 | 0.0% | COM | 58933Y105 |
| — | BIOGEN IDEC INC | 327 | $11.1M | 0.4% | $33944.95 | — | — | Put | 09062X953 |
| GILD | GILEAD SCIENCES INC | 113,260 | $10.68M | 0.3% | $94.26 * | $71.85 | 0.0% | COM | 375558103 |
| — | MANNKIND CORP | 18,865 | $9.838M | 0.3% | $521.49 | — | — | Put | 56400P951 |
| — | SAREPTA THERAPEUTICS INC | 6,572 | $9.51M | 0.3% | $1447.05 | — | — | Call | 803607900 |
| — | AMGEN INC | 580 | $9.239M | 0.3% | $15929.31 | — | — | Call | 031162900 |
| — | TENAX THERAPEUTICS INC | 2,350,567 | $9.026M | 0.3% | $3.84 | $3.93 | — | COM | 88032L100 |
| — | CUBIST PHARMACEUTICALS INC | 873 | $8.787M | 0.3% | $10065.29 | — | — | Call | 229678907 |
| — | DANAHER CORP | 1,000 | $8.571M | 0.3% | $8571.00 | — | — | Call | 235851902 |
| — | DANAHER CORP | 1,000 | $8.571M | 0.3% | $8571.00 | — | — | Put | 235851952 |
| — | TEVA PHARMACEUTICAL INDUSTRIES LTD | 1,481 | $8.517M | 0.3% | $5750.84 | — | — | Put | 881624959 |
| — | COMMUNITY HEALTH SYSTEMS INC | 1,577 | $8.503M | 0.3% | $5391.88 | — | — | Put | 203668958 |
| — | MERCK & CO. INC. | 1,477 | $8.388M | 0.3% | $5679.08 | — | — | Call | 58933Y905 |
| — | MOBILEYE N.V. | 2,058 | $8.347M | 0.3% | $4055.88 | — | — | Put | N51488957 |
| — | BIOMARIN PHARMACEUTICAL INC | 923 | $8.344M | 0.3% | $9040.09 | — | — | Call | 09061G901 |
| — | ELEVEN BIOTHERAPEUTICS IN | 697,470 | $8.286M | 0.3% | $11.88 | $11.92 | — | COM | 286221106 |
| — | PUMA BIOTECHNOLOGY INC | 416 | $7.874M | 0.2% | $18927.88 | — | — | Put | 74587V957 |
| — | AVALANCHE BIOTECHNOLOGIES IN | 142,803 | $7.711M | 0.2% | $54.00 | $47.07 | — | COM | 05337G107 |
| — | BELLICUM PHARMACEUTICALS INC | 331,515 | $7.638M | 0.2% | $23.04 | $23.04 | — | COM | 079481107 |
| — | GILEAD SCIENCES INC | 797 | $7.513M | 0.2% | $9426.60 | — | — | Call | 375558903 |
| — | ISIS PHARMACEUTICALS INC | 1,209 | $7.464M | 0.2% | $6173.70 | — | — | Call | 464330909 |
| — | ALKERMES PLC | 1,256 | $7.355M | 0.2% | $5855.89 | — | — | Put | G01767955 |
| — | MEDIVATION INC | 705 | $7.023M | 0.2% | $9961.70 | — | — | Call | 58501N901 |
| — | ALNYLAM PHARMACEUTICALS INC | 706 | $6.848M | 0.2% | $9699.72 | — | — | Call | 02043Q907 |
| A | AGILENT TECHNOLOGIES INC | 165,008 | $6.755M | 0.2% | $40.94 * | $36.83 | 0.0% | COM | 00846U101 |
| — | COVIDIEN PLC | 65,537 | $6.703M | 0.2% | $102.28 | $86.51 | — | SHS | G2554F113 |
| — | DERMIRA INC | 352,088 | $6.376M | 0.2% | $18.11 | $18.11 | — | COM | 24983L104 |
| — | MANNKIND CORP | 11,468 | $5.981M | 0.2% | $521.54 | — | — | Call | 56400P901 |
| — | CEMPRA INC | 2,536 | $5.962M | 0.2% | $2350.95 | — | — | Call | 15130J909 |
| — | REGULUS THERAPEUTICS INC | 352,278 | $5.651M | 0.2% | $16.04 | $16.04 | — | COM | 75915K101 |
| PRQR | PROQR THRAPEUTICS NV | 253,083 | $5.484M | 0.2% | $21.67 * | $16.02 | -5.3% | SHS | N71542109 |
| — | STEMCELLS INC | 5,793,994 | $5.441M | 0.2% | $0.94 | $1.21 | — | COM | 85857R204 |
| — | ROCKWELL MEDICAL INC | 5,216 | $5.362M | 0.2% | $1027.99 | — | — | Put | 774374952 |
| — | PEREGRINE PHARMACEUTICAL INC | 237,797 | $5.196M | 0.2% | $21.85 | $21.85 | — | COM | 713661304 |
| — | ABBVIE INC | 772 | $5.052M | 0.2% | $6544.04 | — | — | Put | 00287Y959 |
| — | THORATEC CORP | 1,515 | $4.918M | 0.2% | $3246.20 | — | — | Call | 885175907 |
| — | CEMPRA INC | 2,082 | $4.895M | 0.2% | $2351.10 | — | — | Put | 15130J959 |
| — | PERRIGO CO | 287 | $4.797M | 0.2% | $16714.29 | — | — | Call | G97822903 |
| — | DYAX CORP | 3,394 | $4.772M | 0.2% | $1406.01 | — | — | Call | 26746E903 |
| DHR | DANAHER CORP | 55,053 | $4.719M | 0.1% | $85.72 * | $32.92 | 0.0% | COM | 235851102 |
| — | AMERICAN TOWER CORP | 462 | $4.567M | 0.1% | $9885.28 | — | — | Call | 03027X900 |
| — | MANNKIND CORP | 860,751 | $4.489M | 0.1% | $5.22 | $5.69 | — | COM | 56400P201 |
| — | TENET HEALTHCARE CORP | 884 | $4.479M | 0.1% | $5066.74 | — | — | Put | 88033G957 |
| SGMO | SANGAMO BIOSCIENCES INC | 293,500 | $4.464M | 0.1% | $15.21 * | $16.34 | -25.7% | COM | 800677106 |
| — | QUEST RESOURCE HOLDING CORP | 3,017,925 | $4.346M | 0.1% | $1.44 | $1.66 | — | COM | 74836W104 |
| — | ROCKWELL MEDICAL INC | 4,046 | $4.159M | 0.1% | $1027.93 | — | — | Call | 774374902 |
| — | SHIRE PLC | 183 | $3.889M | 0.1% | $21251.37 | — | — | Put | 82481R956 |
| — | CESCA THERAPEUTICS INC | 3,701,695 | $3.775M | 0.1% | $1.02 | $1.41 | — | COM | 157131103 |
| — | NEKTAR THERAPEUTICS | 2,380 | $3.689M | 0.1% | $1550.00 | — | — | Call | 640268908 |
| — | NEUROCRINE BIOSCIENCES INC | 1,614 | $3.606M | 0.1% | $2234.20 | — | — | Put | 64125C959 |
| PBYI | PUMA BIOTECHNOLOGY INC | 18,860 | $3.57M | 0.1% | $189.29 * | $221.87 | 0.0% | COM | 74587V107 |
| — | NEUROCRINE BIOSCIENCES INC | 1,593 | $3.559M | 0.1% | $2234.15 | — | — | Call | 64125C909 |
| — | LPATH INC-CLASS A | 1,248,097 | $3.52M | 0.1% | $2.82 | $3.52 | — | COM | 548910306 |
| — | PLASMATECH BIOPHARMACEUTICAL | 990,595 | $3.467M | 0.1% | $3.50 | $3.50 | — | COM | 72754H109 |
| — | ZAFGEN INC | 111,259 | $3.431M | 0.1% | $30.84 | $19.65 | — | COM | 98885E103 |
| — | ACHILLION PHARMACEUTICALS | 2,719 | $3.331M | 0.1% | $1225.08 | — | — | Call | 00448Q901 |
| — | RICEBRAN TECHNOLOGIES | 799,200 | $3.325M | 0.1% | $4.16 | $4.16 | — | COM | 762831204 |
| — | REPROS THERAPEUTICS INC | 3,161 | $3.152M | 0.1% | $997.15 | — | — | Put | 76028H959 |
| — | INFINITY PHARMACEUTICALS INC | 1,865 | $3.15M | 0.1% | $1689.01 | — | — | Call | 45665G903 |
| — | CELGENE CORP | 280 | $3.132M | 0.1% | $11185.71 | — | — | Call | 151020904 |
| — | ACADIA PHARMACEUTICALS INC | 973 | $3.089M | 0.1% | $3174.72 | — | — | Put | 004225958 |
| — | INFINITY PHARMACEUTICALS INC | 1,807 | $3.052M | 0.1% | $1688.99 | — | — | Put | 45665G953 |
| — | EXACT SCIENCES CORP | 1,072 | $2.942M | 0.1% | $2744.40 | — | — | Put | 30063P955 |
| KEYS | KEYSIGHT TECHNOLOGIES INC | 83,978 | $2.836M | 0.1% | $33.77 * | $32.07 | 0.0% | COM | 49338L103 |
| — | ROCKWELL MEDICAL INC | 275,000 | $2.827M | 0.1% | $10.28 | $9.40 | — | COM | 774374102 |
| — | REPROS THERAPEUTICS INC | 279,879 | $2.79M | 0.1% | $9.97 | $11.55 | — | COM | 76028H209 |
| — | INTREXON CORP | 1,000 | $2.753M | 0.1% | $2753.00 | — | — | Call | 46122T902 |
| — | OCERA THERAPEUTICS INC | 429,945 | $2.739M | 0.1% | $6.37 | $6.37 | — | COM | 67552A108 |
| — | INTREXON CORP | 987 | $2.717M | 0.1% | $2752.79 | — | — | Put | 46122T952 |
| — | AUSPEX PHARMACEUTICALS INC | 50,000 | $2.624M | 0.1% | $52.48 | $24.26 | — | COM | 05211J102 |
| — | CELSUS THERAPEUTICS | 538,703 | $2.586M | 0.1% | $4.80 | $6.29 | — | ADR | 15119A202 |
| — | T2 BIOSYSTEMS INC | 133,809 | $2.574M | 0.1% | $19.24 | $18.33 | — | COM | 89853L104 |
| — | MEI PHARMA INC | 600,000 | $2.562M | 0.1% | $4.27 | $5.18 | — | COM | 55279B202 |
| — | REGULUS THERAPEUTIC INC | 11,000 | $2.5M | 0.1% | $227.27 | — | — | Call | 75915K901 |
| — | THERAPEUTICSMD INC | 549,864 | $2.447M | 0.1% | $4.45 | $4.45 | — | COM | 88338N107 |
| — | DICERNA PHARMACEUTICALS INC | 145,919 | $2.403M | 0.1% | $16.47 | $19.65 | — | COM | 253031108 |
| TRUP | TRUPANION INC | 345,205 | $2.392M | 0.1% | $6.93 * | $8.40 | -21.9% | COM | 898202106 |
| — | TEVA PHARMACEUTICAL INDUSTRIES LTD | 416 | $2.392M | 0.1% | $5750.00 | — | — | Call | 881624909 |
| OCUL | OCULAR THERAPEUTIX INC | 98,951 | $2.327M | 0.1% | $23.52 * | $14.79 | +13.7% | COM | 67576A100 |
| CYH | COMMUNITY HEALTH SYSTEMS INC | 43,027 | $2.32M | 0.1% | $53.92 * | $42.78 | 0.0% | COM | 203668108 |
| — | CARDICA INC | 3,146,657 | $2.203M | 0.1% | $0.70 | $0.82 | — | COM | 14141R101 |
| — | RECRO PHARMA INC | 767,836 | $2.196M | 0.1% | $2.86 | $3.94 | — | COM | 75629F109 |
| — | BIODEL INC | 1,615,143 | $2.148M | 0.1% | $1.33 | $1.72 | — | COM | 09064M204 |
| — | IGNYTA INC | 311,191 | $2.132M | 0.1% | $6.85 | $7.78 | — | COM | 451731103 |
| — | NPS PHARMACEUTICALS INC | 594 | $2.125M | 0.1% | $3577.44 | — | — | Call | 62936P903 |
| — | NOVAVAX INC | 3,478 | $2.062M | 0.1% | $592.87 | — | — | Call | 670002904 |
| FOLD | AMICUS THERAPEUTICS INC | 246,697 | $2.053M | 0.1% | $8.32 * | $6.86 | 0.0% | COM | 03152W109 |
| — | SHIRE PLC | 9,652 | $2.051M | 0.1% | $212.49 | $476.24 | — | ADR | 82481R106 |
| — | INCYTE CORP | 273 | $1.996M | 0.1% | $7311.36 | — | — | Put | 45337C952 |
| — | TESARO INC | 534 | $1.986M | 0.1% | $3719.10 | — | — | Call | 881569907 |
| — | MAST THERAPEUTICS INC | 3,539,779 | $1.982M | 0.1% | $0.56 | $0.56 | — | COM | 576314108 |
| — | XOMA CORP | 5,507 | $1.977M | 0.1% | $359.00 | — | — | Call | 98419J907 |
| — | INSPIREMD INC | 2,517,334 | $1.957M | 0.1% | $0.78 | $0.78 | — | COM | 45779A309 |
| — | CELLECTAR BIOSCIENCES INC | 619,632 | $1.915M | 0.1% | $3.09 | $2.27 | — | COM | 15117F203 |
| — | ENDO INTERNATIONAL PLC | 253 | $1.825M | 0.1% | $7213.44 | — | — | Call | G30401906 |
| — | SALIX PHARMACEUTICALS INC | 158 | $1.816M | 0.1% | $11493.67 | — | — | Call | 795435906 |
| — | NORTHWEST BIOTHERAPEUTICS INC | 3,394 | $1.816M | 0.1% | $535.06 | — | — | Put | 66737P950 |
| — | XOMA CORP | 501,745 | $1.801M | 0.1% | $3.59 | $4.30 | — | COM | 98419J107 |
| — | REGENERON PHARMACEUTICALS INC | 43 | $1.764M | 0.1% | $41023.26 | — | — | Call | 75886F907 |
| — | WAFERGEN BIO-SYSTEMS INC | 585,255 | $1.756M | 0.1% | $3.00 | $4.28 | — | COM | 93041P308 |
| — | REPROS THERAPEUTICS INC | 1,748 | $1.743M | 0.1% | $997.14 | — | — | Call | 76028H909 |
| — | SPDR S&P BIOTECH ETF SHS | 89 | $1.661M | 0.1% | $18662.92 | — | — | Put | 78464A950 |
| — | CTI BIOPHARMA CORP | 6,956 | $1.642M | 0.1% | $236.06 | — | — | Call | 12648L906 |
| HRTX | HERON THERAPEUTICS INC | 162,900 | $1.639M | 0.1% | $10.06 * | $11.24 | -27.4% | COM | 427746102 |
| — | IDERA PHARMACEUTICALS INC | 3,652 | $1.611M | 0.1% | $441.13 | — | — | Call | 45168K906 |
| — | RECEPTOS INC | 130 | $1.593M | 0.1% | $12253.85 | — | — | Call | 756207906 |
| — | ARIAD PHARMACEUTICALS INC | 2,311 | $1.588M | 0.1% | $687.15 | — | — | Put | 04033A950 |
| SRPT | SAREPTA THERAPEUTICS INC | 105,000 | $1.519M | 0.0% | $14.47 * | $36.12 | -53.1% | COM | 803607100 |
| — | BIOLINERX LTD | 928,758 | $1.505M | 0.0% | $1.62 | $1.62 | — | ADR | 09071M106 |
| — | NPS PHARMACEUTICALS INC | 41,670 | $1.491M | 0.0% | $35.78 | $34.83 | — | COM | 62936P103 |
| — | ONCOTHYREON INC | 724,500 | $1.377M | 0.0% | $1.90 | $1.92 | — | COM | 682324108 |
| — | SKYSTAR BIO-PHARMACEUTICAL | 314,367 | $1.333M | 0.0% | $4.24 | $4.19 | — | COM | 830884300 |
| — | AMICUS THERAPEUTICS INC | 1,597 | $1.329M | 0.0% | $832.19 | — | — | Put | 03152W959 |
| — | REVANCE THERAPEUTICS INC | 76,400 | $1.294M | 0.0% | $16.94 | $29.62 | — | COM | 761330109 |
| — | OPKO HEALTH INC | 1,277 | $1.276M | 0.0% | $999.22 | — | — | Put | 68375N953 |
| — | OXIGENE INC | 782,674 | $1.26M | 0.0% | $1.61 | $2.56 | — | COM | 691828404 |
| — | FOAMIX PHARMACEUTICALS LTD | 163,300 | $1.145M | 0.0% | $7.01 | $5.45 | — | SHS | M46135105 |
| — | CASI PHARMACEUTICALS INC | 836,092 | $1.112M | 0.0% | $1.33 | $1.76 | — | COM | 14757U109 |
| — | ONCOGENEX PHARMACEUTICAL INC | 461,957 | $1.058M | 0.0% | $2.29 | $3.73 | — | COM | 68230A106 |
| — | CELSION CORP | 453,356 | $1.056M | 0.0% | $2.33 | $2.58 | — | COM | 15117N404 |
| — | AEGERION PHARMACEUTICALS INC | 500 | $1.047M | 0.0% | $2094.00 | — | — | Call | 00767E902 |
| — | CYTORI THERAPEUTICS INC | 2,096,392 | $1.025M | 0.0% | $0.49 | $1.56 | — | COM | 23283K105 |
| — | GALENA BIOPHARMA INC | 6,600 | $997K | 0.0% | $151.06 | — | — | Put | 363256958 |
| — | CYMABAY THERAPEUTICS INC | 100,800 | $991K | 0.0% | $9.83 | $6.84 | — | COM | 23257D103 |
| — | HEARTWARE INTERNATIONAL INC | 133 | $977K | 0.0% | $7345.86 | — | — | Put | 422368950 |
| — | VERICEL CORP | 311,800 | $948K | 0.0% | $3.04 | $3.04 | — | COM | 82346J108 |
| — | MEDGENICS INC-CW18 | 1,271,240 | $922K | 0.0% | $0.73 | $1.01 | — | *W | 58436Q112 |
| — | CELSION CORP | 3,892 | $907K | 0.0% | $233.04 | — | — | Put | 15117N954 |
| — | NANOSPHERE INC | 2,225,081 | $872K | 0.0% | $0.39 | $0.39 | — | COM | 63009F105 |
| — | MOBILEYE N.V. | 208 | $844K | 0.0% | $4057.69 | — | — | Call | N51488907 |
| — | PLASMATECH BIOPHARMACEU-CW19 | 1,016,725 | $834K | 0.0% | $0.82 | $0.82 | — | *W | 72754H117 |
| — | ESPERION THERAPEUTICS INC | 206 | $833K | 0.0% | $4043.69 | — | — | Call | 29664W905 |
| ALKS | ALKERMES PLC | 13,827 | $810K | 0.0% | $58.58 * | $44.82 | +13.6% | SHS | G01767105 |
| — | REGADO BIOSCIENCE INC | 862,549 | $788K | 0.0% | $0.91 | $1.86 | — | COM | 75874Q107 |
| — | CELGENE CORP | 70 | $783K | 0.0% | $11185.71 | — | — | Put | 151020954 |
| INCY | INCYTE CORP | 10,564 | $772K | 0.0% | $73.08 * | $65.33 | 0.0% | COM | 45337C102 |
| — | TENET HEALTHCARE CORP | 150 | $760K | 0.0% | $5066.67 | — | — | Call | 88033G907 |
| — | HORIZON PHARMA PLC | 586 | $755K | 0.0% | $1288.40 | — | — | Call | G4617B905 |
| — | MELA SCIENCES INC | 599,262 | $719K | 0.0% | $1.20 | $1.26 | — | COM | 55277R308 |
| — | VANDA PHARMACEUTICALS INC | 500 | $716K | 0.0% | $1432.00 | — | — | Call | 921659908 |
| — | NEUROMETRIX INC | 362,874 | $708K | 0.0% | $1.95 | $1.87 | — | COM | 641255302 |
| — | AGILENT TECHNOLOGIES INC | 171 | $700K | 0.0% | $4093.57 | — | — | Put | 00846U951 |
| — | SEATTLE GENETICS INC | 211 | $678K | 0.0% | $3213.27 | — | — | Call | 812578902 |
| — | GEVO INC | 1,878,020 | $601K | 0.0% | $0.32 | $0.41 | — | COM | 374396109 |
| — | CTI BIOPHARMA CORP | 245,000 | $578K | 0.0% | $2.36 | $2.36 | — | COM | 12648L106 |
| — | SEATTLE GENETICS INC | 176 | $565K | 0.0% | $3210.23 | — | — | Put | 812578952 |
| — | SEATTLE GENETICS INC | 17,378 | $558K | 0.0% | $32.11 | $37.18 | — | COM | 812578102 |
| — | HISTOGENICS CORP | 50,367 | $554K | 0.0% | $11.00 | $11.00 | — | COM | 43358V109 |
| — | ARROWHEAD RESEARCH CORP | 727 | $537K | 0.0% | $738.65 | — | — | Put | 42797959 |
| — | XOMA CORP | 1,425 | $512K | 0.0% | $359.30 | — | — | Put | 98419J957 |
| — | CELLECTAR BIOSCIENCES-CW19 | 630,900 | $505K | 0.0% | $0.80 | $0.61 | — | *W | 15117F112 |
| — | PROGENICS PHARMACEUTICALS INC | 63,999 | $484K | 0.0% | $7.56 | $7.56 | — | COM | 743187106 |
| — | INSMED INC | 296 | $458K | 0.0% | $1547.30 | — | — | Call | 457669907 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 5,039 | $456K | 0.0% | $90.49 * | $83.16 | 0.0% | COM | 09061G101 |
| — | AMICUS THERAPEUTICS INC | 546 | $454K | 0.0% | $831.50 | — | — | Call | 03152W909 |
| — | MEDICINES COMPANY | 162 | $448K | 0.0% | $2765.43 | — | — | Put | 584688955 |
| — | ARIAD PHARMACEUTICALS INC | 63,888 | $439K | 0.0% | $6.87 | $6.01 | — | COM | 04033A100 |
| — | CEL-SCI CORP-CW18 | 3,064,745 | $438K | 0.0% | $0.14 | $0.42 | — | *W | 150837177 |
| — | HORIZON PHARMA PLC | 331 | $427K | 0.0% | $1290.03 | — | — | Put | G4617B955 |
| — | OHR PHARMACEUTICAL INC | 50,000 | $417K | 0.0% | $8.34 | $9.51 | — | COM | 67778H200 |
| — | ACHILLION PHARMACEUTICALS | 296 | $363K | 0.0% | $1226.35 | — | — | Put | 00448Q951 |
| — | AGIOS PHARMACEUTICALS INC | 32 | $359K | 0.0% | $11218.75 | — | — | Put | 00847X904 |
| — | PHARMACYCLICS INC | 29 | $355K | 0.0% | $12241.38 | — | — | Put | 716933956 |
| — | KERYX BIOPHARMACEUTICALS | 250 | $354K | 0.0% | $1416.00 | — | — | Call | 492515901 |
| — | SYNERGY PHARMACEUTICALS-CW16 | 460,745 | $336K | 0.0% | $0.73 | $1.23 | — | *W | 871639118 |
| — | ALKERMES PLC | 54 | $316K | 0.0% | $5851.85 | — | — | Call | G01767905 |
| — | ALEXZA PHARMACEUTICALS INC | 2,040 | $304K | 0.0% | $149.02 | — | — | Call | 015384209 |
| — | EXELIXIS INC | 2,014 | $290K | 0.0% | $143.99 | — | — | Call | 30161Q904 |
| — | INTELLIPHARMACEUTICS INTL INC | 1,265 | $286K | 0.0% | $226.09 | — | — | Put | 458173951 |
| — | CELATOR PHARMACEUTICALS INC | 140,234 | $275K | 0.0% | $1.96 | $2.91 | — | COM | 15089R102 |
| — | ORIENT PAPER INC | 238,800 | $265K | 0.0% | $1.11 | $1.38 | — | COM | 68619F205 |
| — | ATHERSYS INC | 1,599 | $253K | 0.0% | $158.22 | — | — | Put | 04744L956 |
| — | AMERICAN TOWER CORP | 25 | $247K | 0.0% | $9880.00 | — | — | Put | 03027X950 |
| SMLR | SEMLER SCIENTIFIC INC | 115,423 | $226K | 0.0% | $1.96 * | $6.18 | -60.8% | COM | 81684M104 |
| — | COMMUNITY HEALTH SYSTEMS INC | 42 | $226K | 0.0% | $5380.95 | — | — | Call | 203668908 |
| — | PHARMATHENE INC | 1,220 | $221K | 0.0% | $181.15 | — | — | Call | 71714G902 |
| — | GALENA BIOPHARMA INC | 140,944 | $213K | 0.0% | $1.51 | $2.47 | — | COM | 363256108 |
| — | PLURISTEM THERAPEUTICS INC | 771 | $193K | 0.0% | $250.32 | — | — | Put | 72940R952 |
| — | LEXICON PHARMACEUTICALS INC | 202,700 | $184K | 0.0% | $0.91 | $0.91 | — | COM | 528872104 |
| — | KERYX BIOPHARMACEUTICALS | 128 | $181K | 0.0% | $1414.06 | — | — | Put | 492515951 |
| — | ARIAD PHARMACEUTICALS INC | 259 | $178K | 0.0% | $687.26 | — | — | Call | 04033A900 |
| — | CONATUS PHARMACEUTICALS INC | 169 | $118K | 0.0% | $698.22 | — | — | Call | 20600T908 |
| — | DARA BIOSCIENCES INC | 124,890 | $110K | 0.0% | $0.88 | $0.88 | — | COM | 23703P304 |
| — | CLEVELAND BIOLABS INC | 377,156 | $108K | 0.0% | $0.29 | $0.54 | — | COM | 185860103 |
| — | HCA HOLDINGS INC | 192 | $107K | 0.0% | $557.29 | — | — | Call | 40412C901 |
| — | THERAPEUTICSMD INC | 214 | $95,000 | 0.0% | $443.93 | — | — | Call | 88338N907 |
| — | TROVAGENE INC | 20,000 | $86,000 | 0.0% | $4.30 | $5.75 | — | COM | 897238309 |
| — | ATHERSYS INC | 508 | $80,000 | 0.0% | $157.48 | — | — | Call | 04744L906 |
| EXEL | EXELIXIS INC | 45,622 | $66,000 | 0.0% | $1.45 * | $5.28 | -70.5% | COM | 30161Q104 |
| — | CTI BIOPHARMA CORP | 256 | $60,000 | 0.0% | $234.38 | — | — | Put | 12648L956 |
| GALT | GALECTIN THERAPEUTICS INC | 15,842 | $55,000 | 0.0% | $3.47 * | $4.42 | 0.0% | COM | 363225202 |
| — | CERES INC | 222,600 | $53,000 | 0.0% | $0.24 | $0.88 | — | COM | 156773103 |
| — | INTELLIPHARMACEUTICS INTL INC | 20,626 | $47,000 | 0.0% | $2.28 | $2.28 | — | COM | 458173101 |
| — | ARENA PHARMACEUTICALS INC | 130 | $45,000 | 0.0% | $346.15 | — | — | Call | 040047902 |
| — | EDAP TMS SA | 168 | $39,000 | 0.0% | $232.14 | — | — | Put | 268311957 |
| — | CYTRX CORP | 100 | $27,000 | 0.0% | $270.00 | — | — | Put | 232828959 |
| — | BIODEL INC | 182 | $24,000 | 0.0% | $131.87 | — | — | Put | 09064M954 |
| — | GALENA BIOPHARMA INC | 139 | $21,000 | 0.0% | $151.08 | — | — | Call | 363256908 |
| — | CEL-SCI CORP | 12,888 | $8,000 | 0.0% | $0.62 | $0.59 | — | COM | 150837508 |