Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	SPDR S&P 500 ETF TRUST	16,250	$307M	12.6%	—	—	Put	78462F953
—	ISHARES RUSSELL 2000 ETF	25,500	$273M	11.3%	—	—	Put	464287955
—	ELI LILLY & CO	21,855	$183M	7.5%	—	—	Call	532457908
—	GILEAD SCIENCES INC	9,896	$97.17M	4.0%	—	—	Call	375558903
—	BIOGEN IDEC INC	3,090	$90.17M	3.7%	—	—	Call	09062X903
—	GILEAD SCIENCES INC	4,973	$48.83M	2.0%	—	—	Put	375558953
—	MEDICINES CO	11,749	$44.6M	1.8%	—	—	Call	584688905
—	ZOGENIX INC	31,115	$42.01M	1.7%	—	—	Call	98978L904
—	BIOGEN IDEC INC	1,419	$41.41M	1.7%	—	—	Put	09062X953
—	ABBVIE INC	7,456	$40.57M	1.7%	—	—	Call	00287Y909
IWM	ISHARES RUSSELL 2000 ETF	327,168	$35.73M	1.5%	$109.20	—	ETF	464287655
—	EDWARDS LIFESCIENCES CORP	1,682	$34.9M	1.4%	—	—	Put	28176E958
—	BIOMARIN PHARMACEUTICAL INC	2,911	$30.66M	1.3%	—	—	Put	09061G951
—	TENET HEALTHCARE CORP	7,745	$28.59M	1.2%	—	—	Call	88033G907
—	BIOMARIN PHARMACEUTICAL INC	2,375	$25.01M	1.0%	—	—	Call	09061G901
—	GW PHARMACEUTICALS PLC	2,712	$24.78M	1.0%	—	—	Put	36197T953
—	MOBILEYE N.V.	5,158	$23.46M	1.0%	—	—	Put	N51488957
—	MYLAN N.V.	5,756	$23.17M	1.0%	—	—	Put	N59465959
BIIB	BIOGEN IDEC INC	78,629	$22.95M	0.9%	$330.23	0.0%	COM	09062X103
—	SAREPTA THERAPEUTICS INC	6,671	$21.42M	0.9%	—	—	Call	803607900
—	ELI LILLY & CO	2,438	$20.4M	0.8%	—	—	Put	532457958
—	SPDR SERIES TRUST	3,144	$19.57M	0.8%	—	—	Put	78464A950
BMRN	BIOMARIN PHARMACEUTICAL INC	174,073	$18.33M	0.8%	$133.58	0.0%	COM	09061G101
—	BRISTOL MYERS SQUIBB CO	3,073	$18.19M	0.7%	—	—	Call	110122908
—	ALEXION PHARMACEUTICALS INC	975	$15.25M	0.6%	—	—	Put	015351959
—	MYLAN N.V.	376,827	$15.17M	0.6%	$40.26	—	SHS	N59465109
—	PIONEER NATURAL RESOURCE INC	123,600	$15.04M	0.6%	$132.16	—	COM	723787107
—	PIONEER NATURAL RESOURCE INC	1,236	$15.04M	0.6%	—	—	Put	723787957
—	GLOBAL BLOOD THERAPEUTICS INC	342,857	$14.46M	0.6%	$42.16	—	COM	37890U108
—	ALNYLAM PHARMACEUTICALS INC	1,676	$13.47M	0.6%	—	—	Call	02043Q907
—	NEWLINK GENETICS CORP	3,701	$13.26M	0.5%	—	—	Call	651511907
—	ABBVIE INC	2,272	$12.36M	0.5%	—	—	Put	00287Y959
—	APPLE INC	1,110	$12.24M	0.5%	—	—	Call	037833900
—	UNITED THERAPEUTICS CORP	918	$12.05M	0.5%	—	—	Call	91307C902
—	INTEROIL CORP	3,356	$11.31M	0.5%	—	—	Put	460951956
—	INTEROIL CORP	328,705	$11.08M	0.5%	$45.11	—	COM	460951106
EW	EDWARDS LIFESCIENCES CORP	77,255	$10.98M	0.5%	$23.77	+1.5%	COM	28176E108
—	TENET HEALTHCARE CORP	2,907	$10.73M	0.4%	—	—	Put	88033G957
—	MOBILEYE N.V.	235,819	$10.72M	0.4%	$44.40	—	ORD	N51488117
—	HERON THERAPEUTICS INC	4,223	$10.3M	0.4%	—	—	Call	427746902
—	CEMPRA INC	3,649	$10.16M	0.4%	—	—	Call	15130J909
—	KITE PHARMA INC	1,823	$10.15M	0.4%	—	—	Put	49803L959
—	MANNKIND CORP	30,930	$9.929M	0.4%	—	—	Call	56400P901
—	GEVO INC	100,000	$9.819M	0.4%	$3.27	—	COM	374396208
THC	TENET HEALTHCARE CORP	245,938	$9.08M	0.4%	$51.67	0.0%	COM	88033G407
—	ACORDA THERAPEUTICS INC NOTE 1.75%	9,600,000	$8.664M	0.4%	$0.90	—	NOTE	00484MAA4
—	AGIOS PHARMACEUTICALS INC	1,173	$8.28M	0.3%	—	—	Put	00847X954
—	REGULUS THERAPEUTIC INC	12,127	$7.931M	0.3%	—	—	Call	75915K901
—	TENAX THERAPEUTICS INC	2,604,660	$7.892M	0.3%	$3.82	—	COM	88032L100
AGIO	AGIOS PHARMACEUTICALS INC	109,521	$7.731M	0.3%	$97.74	0.0%	COM	00847X104
—	ALEXION PHARMACEUTICALS INC	49,397	$7.725M	0.3%	$164.23	—	COM	015351109
—	EXACT SCIENCES CORP	4,293	$7.723M	0.3%	—	—	Put	30063P955
—	PERRIGO CO. PLC	491	$7.722M	0.3%	—	—	Call	G97822903
—	KITE PHARMA INC	137,099	$7.634M	0.3%	$55.82	—	COM	49803L109
—	BLUEBIRD BIO INC	889	$7.605M	0.3%	—	—	Call	09609G900
—	ACADIA PHARMACEUTICALS INC	2,259	$7.471M	0.3%	—	—	Put	004225958
—	MEDICINES CO 1.375%	5,000,000	$7.278M	0.3%	$1.19	—	DBCV	584688AC9
—	MYLAN N.V.	1,747	$7.033M	0.3%	—	—	Call	N59465909
—	TOKAI PHARMACEUTICALS ORD SHS	654,283	$6.772M	0.3%	$10.93	—	COM	88907J107
—	MANNKIND CORP	20,875	$6.701M	0.3%	—	—	Put	56400P951
—	BLUEPRINT MEDICINES INC	308,504	$6.583M	0.3%	$26.38	—	COM	09627Y109
—	GW PHARMACEUTICALS PLC	71,757	$6.556M	0.3%	$91.30	—	ADS	36197T103
—	BIOMARIN PHARMACEUTICAL INC. NOTE .75%	5,000,000	$6.459M	0.3%	$1.49	—	NOTE	09061GAE1
—	ALNYLAM PHARMACEUTICALS INC	789	$6.34M	0.3%	—	—	Put	02043Q957
—	ANADARKO PETROLEUM CORP	102,300	$6.178M	0.3%	$76.10	—	COM	032511107
—	ANADARKO PETROLEUM CORP	1,023	$6.178M	0.3%	—	—	Put	032511957
—	NOVAVAX INC	8,418	$5.952M	0.2%	—	—	Put	670002954
—	SAREPTA THERAPEUTICS INC	1,836	$5.895M	0.2%	—	—	Put	803607950
—	BARCLAYS BANK PLC	450,500	$5.861M	0.2%	$11.18	—	ETN	06740C519
—	SPARK THERAPEUTICS INC	1,402	$5.851M	0.2%	—	—	Call	84652J903
—	SPARK THERAPEUTICS INC	1,379	$5.755M	0.2%	—	—	Put	84652J953
—	THERAPEUTICSMD INC	9,800	$5.743M	0.2%	—	—	Call	88338N907
—	NEUROCRINE BIOSCIENCES INC	1,403	$5.583M	0.2%	—	—	Call	64125C909
—	KONINKLIJKE PHILIPS N V	2,374	$5.569M	0.2%	—	—	Call	500472903
—	INTRA-CELLULAR THERAPIES INC	1,378	$5.518M	0.2%	—	—	Call	46116X901
—	OPKO HEALTH INC	6,456	$5.429M	0.2%	—	—	Put	68375N953
—	HALOZYME THERAPEUTICS INC	4,014	$5.391M	0.2%	—	—	Call	40637H909
EXAS	EXACT SCIENCES CORP	289,112	$5.201M	0.2%	$22.97	0.0%	COM	30063P105
OPK	OPKO HEALTH INC	615,157	$5.173M	0.2%	$13.34	-0.8%	COM	68375N103
LAB	FLUIDIGM CORP DEL	628,260	$5.095M	0.2%	$19.90	-20.9%	COM	34385P108
—	DYNAVAX TECHNOLOGIES CORP	2,073	$5.087M	0.2%	—	—	Call	268158901
—	DEPOMED INC	2,680	$5.052M	0.2%	—	—	Call	249908904
—	GENOCEA BIOSCIENCES INC	729,141	$4.995M	0.2%	$8.18	—	COM	372427104
—	NIVALIS THERAPEUTICS INC	384,734	$4.99M	0.2%	$15.15	—	COM	65481J109
—	HCA HOLDINGS INC	624	$4.827M	0.2%	—	—	Call	40412C901
—	ACHILLION PHARMACEUTICALS INC	6,916	$4.779M	0.2%	—	—	Call	00448Q901
—	ACADIA PHARMACEUTICALS INC	1,438	$4.755M	0.2%	—	—	Call	004225908
—	AVALANCHE BIOTECHNOLOGIES INC	574,260	$4.732M	0.2%	$13.94	—	COM	05337G107
—	CELLDEX THERAPEUTICS INC	4,448	$4.688M	0.2%	—	—	Call	15117B903
—	ISIS PHARMACEUTICALS INC	1,159	$4.685M	0.2%	—	—	Call	464330909
—	DERMIRA INC	190,000	$4.435M	0.2%	$18.06	—	COM	24983L104
GILD	GILEAD SCIENCES INC	45,140	$4.432M	0.2%	$77.50	0.0%	COM	375558103
ABUS	ARBUTUS BIOPHARMA CORP	725,007	$4.415M	0.2%	$8.87	0.0%	COM	03879J100
—	RAPTOR PHARMACEUTICAL CORP	7,289	$4.41M	0.2%	—	—	Call	75382F906
—	NEUROCRINE BIOSCIENCES INC	1,267	$4.397M	0.2%	—	—	Put	64125C959
—	INOVIO PHARMACEUTICALS INC	737,551	$4.263M	0.2%	$8.16	—	COM	45773H201
—	ZS PHARMA INC	640	$4.202M	0.2%	—	—	Put	98979G955
—	ENDO INTERNATIONAL PLC	601	$4.164M	0.2%	—	—	Call	G30401906
—	RADIUS HEALTH INC	578	$4.006M	0.2%	—	—	Call	750469907
HRTX	HERON THERAPEUTICS INC	160,323	$3.912M	0.2%	$33.33	0.0%	COM	427746102
—	CIDARA THERAPEUTICS	306,044	$3.893M	0.2%	$13.97	—	COM	171757107
—	OPKO HEALTH INC	4,500	$3.785M	0.2%	—	—	Call	68375N903
—	NORTHWEST BIOTHERAPEUTICS INC	6,042	$3.776M	0.2%	—	—	Put	66737P950
—	NOVAVAX INC	527,040	$3.726M	0.2%	$7.07	—	COM	670002104
—	TRANSENTERIX INC	1,591,117	$3.596M	0.1%	$3.00	—	COM	89366M201
NWBO	NORTHWEST BIOTHERAPEUTICS INC	572,518	$3.578M	0.1%	$9.01	+3.8%	COM	66737P600
—	VERTEX PHARMACEUTICALS INC	341	$3.551M	0.1%	—	—	Call	92532F900
—	ENDO INTERNATIONAL PLC	50,658	$3.51M	0.1%	$82.08	—	SHS	G30401106
—	BLUEBIRD BIO INC	406	$3.473M	0.1%	—	—	Put	09609G950
—	NEVRO CORP	745	$3.456M	0.1%	—	—	Put	64157F953
SKY	SKYLINE MEDICAL UNITS	447,944	$3.454M	0.1%	$3.15	0.0%	COM	830830105
—	INTEC PHARMA LTD	613,910	$3.438M	0.1%	$5.60	—	SHS	M53644106
—	DYNAVAX TECHNOLOGIES CORP	134,954	$3.312M	0.1%	$23.96	—	COM	268158201
—	HORIZON PHARMA PLC	1,658	$3.286M	0.1%	—	—	Put	G4617B955
—	HORIZON PHARMA PLC	164,658	$3.264M	0.1%	$19.82	—	SHS	G4617B105
—	AMICUS THERAPEUTICS INC	2,322	$3.248M	0.1%	—	—	Put	03152W959
—	LION BIOTECHNOLOGIES INC	561,894	$3.237M	0.1%	$10.32	—	COM	53619R102
—	ZELTIQ AESTHETICS INC	1,000	$3.203M	0.1%	—	—	Call	98933Q908
AOXG	AOXING PHARMACEUTICAL INC	2,134,054	$3.158M	0.1%	$1.58	0.0%	COM	03740A106
VRTX	VERTEX PHARMACEUTICALS INC	30,000	$3.124M	0.1%	$128.47	0.0%	COM	92532F100
—	MOBILEYE N.V.	686	$3.12M	0.1%	—	—	Call	N51488907
—	BENITEC BIOPHARMA LTD	505,220	$3.107M	0.1%	$6.15	—	ADR	082053307
—	PTC THERAPEUTICS INC	1,161	$3.1M	0.1%	—	—	Call	69366J900
—	ZAFGEN INC	960	$3.067M	0.1%	—	—	Call	98885E903
—	NEUROMETRIX EQUITY WARRANTS	12,212,278	$3.052M	0.1%	$0.20	—	*W	641255138
—	CEMPRA INC	1,082	$3.012M	0.1%	—	—	Put	15130J959
—	NOVAVAX INC	4,018	$2.841M	0.1%	—	—	Call	670002904
—	COMMUNITY HEALTH SYSTEMS INC	662	$2.831M	0.1%	—	—	Put	203668958
LXRX	LEXICON PHARMACEUTICALS INC	261,595	$2.81M	0.1%	$7.34	+48.7%	COM	528872302
—	PLURISTEM THERAPEUTICS INC	1,474,369	$2.683M	0.1%	$2.53	—	COM	72940R102
—	MEDGENICS EQUITY WARRANTS	1,453,640	$2.544M	0.1%	$1.00	—	*W	58436Q112
—	OVASCIENCE INC	297,955	$2.53M	0.1%	$2.26	—	COM	69014Q101
—	FEI CO	340	$2.483M	0.1%	—	—	Call	30241L909
—	REGENERON PHARMACEUTICALS INC	53	$2.465M	0.1%	—	—	Put	75886F957
SGMO	SANGAMO BIOSCIENCES INC	435,225	$2.455M	0.1%	$13.76	-40.1%	COM	800677106
—	REVANCE THERAPEUTICS INC	815	$2.425M	0.1%	—	—	Call	761330909
—	LIPOCINE INC	201,409	$2.383M	0.1%	$8.58	—	COM	53630X104
—	ALEXION PHARMACEUTICALS INC	152	$2.377M	0.1%	—	—	Call	015351909
—	LA JOLLA PHARMACEUTICAL CO	85,011	$2.362M	0.1%	$27.78	—	COM	503459604
—	REGULUS THERAPEUTIC INC	356,504	$2.332M	0.1%	$14.53	—	COM	75915K101
—	INOVIO PHARMACEUTICALS INC	3,965	$2.292M	0.1%	—	—	Call	45773H901
—	TRANSENTERIX INC	10,026	$2.266M	0.1%	—	—	Call	89366M901
—	INVIVO THERAPEUTICS HOLDINGS CORP	2,608	$2.248M	0.1%	—	—	Call	46186M909
—	REDHILL BIOPHARMA LTD	173,550	$2.241M	0.1%	$12.91	—	ADS	757468103
—	PARATEK PHARMACEUTICALS INC	117,046	$2.224M	0.1%	$22.22	—	COM	699374302
—	IGNYTA ORD SHS	252,974	$2.221M	0.1%	$8.13	—	COM	451731103
—	BIOCRYST PHARMACEUTICALS INC	1,929	$2.199M	0.1%	—	—	Put	09058V953
—	PUMA BIOTECHNOLOGY INC	288	$2.17M	0.1%	—	—	Put	74587V957
—	CYTOKINETICS INC	3,106	$2.078M	0.1%	—	—	Call	23282W905
—	REPROS THERAPEUTICS INC	2,793	$2.075M	0.1%	—	—	Put	76028H959
—	MIRATI THERAPEUTICS INC	60,000	$2.065M	0.1%	$34.42	—	COM	60468T105
—	REPROS THERAPEUTICS INC	2,777	$2.063M	0.1%	—	—	Call	76028H909
—	BIODELIVERY SCIENCES INTERNATIONAL INC	368,641	$2.05M	0.1%	$6.44	—	COM	09060J106
—	CEMPRA INC	73,195	$2.038M	0.1%	$34.31	—	COM	15130J109
—	VAPOR CORP DEL	225,387	$2.015M	0.1%	$8.94	—	UNIT	922099502
PBYI	PUMA BIOTECHNOLOGY INC	26,704	$2.012M	0.1%	$94.57	0.0%	COM	74587V107
—	RICEBRAN TECHNOLOGIES	901,973	$1.975M	0.1%	$3.97	—	COM	762831204
—	VASCULAR SOLUTIONS INC	607	$1.967M	0.1%	—	—	Put	92231M959
—	BRAINSTORM CELL THERAPEUTICS	852,348	$1.952M	0.1%	$4.17	—	COM	10501E201
—	ZS PHARMA INC	297	$1.95M	0.1%	—	—	Call	98979G905
—	DYAX CORP	1,017	$1.941M	0.1%	—	—	Put	26746E953
—	SERES THERAPEUTICS INC	64,775	$1.92M	0.1%	$29.64	—	COM	81750R102
—	SORRENTO THERAPEUTICS INC	2,275	$1.909M	0.1%	—	—	Call	83587F902
—	GLOBUS MEDICAL INC	913	$1.886M	0.1%	—	—	Put	379577958
—	OVASCIENCE INC	2,200	$1.868M	0.1%	—	—	Put	69014Q951
CYH	COMMUNITY HEALTH SYSTEMS INC	43,397	$1.856M	0.1%	$45.85	0.0%	COM	203668108
—	CESCA THERAPEUTICS INC.	3,500,037	$1.855M	0.1%	$1.37	—	COM	157131103
—	CHINA BIOLOGIC PRODUCTS INC	20,000	$1.796M	0.1%	$96.15	—	COM	16938C106
—	QUEST RESOURCE HOLDING	3,148,401	$1.795M	0.1%	$1.62	—	COM	74836W104
—	XTL BIOPHARMACEUTICALS	1,149,886	$1.794M	0.1%	$2.30	—	ADR	98386D208
—	FOAMIX PHARMACEUTICALS LTD	243,361	$1.784M	0.1%	$9.14	—	SHS	M46135105
—	ONCOSEC MEDICAL INC	340,169	$1.752M	0.1%	$6.33	—	COM	68234L207
—	IMMUNOCELLULAR THERAPEUTICS	4,169,243	$1.751M	0.1%	$0.48	—	COM	452536105
ACUR	ACURA PHARMACEUTICALS INC	743,603	$1.747M	0.1%	$3.40	0.0%	COM	00509L802
—	BELLICUM PHARMACEUTICALS INC	120,094	$1.745M	0.1%	$22.97	—	COM	079481107
—	BARCLAYS BANK PLC	1,334	$1.736M	0.1%	—	—	Call	06740C909
—	UNIQURE B.V.	844	$1.726M	0.1%	—	—	Call	N90064901
—	SAGE THERAPEUTICS INC	40,019	$1.694M	0.1%	$61.55	—	COM	78667J108
—	TOBIRA THERAPEUTICS INC	174,943	$1.69M	0.1%	$9.66	—	COM	88883P101
—	NUVASIVE INC	35,000	$1.688M	0.1%	$48.23	—	COM	670704105
—	INFINITY PHARMACEUTICALS INC	1,971	$1.665M	0.1%	—	—	Call	45665G903
—	FORWARD PHARMA A/S	70,000	$1.649M	0.1%	$25.94	—	ADR	34986J105
—	AGIOS PHARMACEUTICALS INC	233	$1.645M	0.1%	—	—	Call	00847X904
—	MOMENTA PHARMACEUTICALS INC	1,000	$1.641M	0.1%	—	—	Call	60877T900
—	OMEROS CORP	1,489	$1.632M	0.1%	—	—	Call	682143902
—	APPLIED GENETIC TECHNOLOGIES CORP	124,000	$1.629M	0.1%	$19.39	—	COM	03820J100
—	AMARIN CORPORATION PLC	8,183	$1.579M	0.1%	—	—	Call	023111206
—	ENDO INTERNATIONAL PLC	224	$1.552M	0.1%	—	—	Put	G30401956
—	NUVASIVE INC	320	$1.543M	0.1%	—	—	Call	670704905
—	NEWLINK GENETICS CORP	430	$1.541M	0.1%	—	—	Put	651511957
—	CARDICA INC	5,281,185	$1.521M	0.1%	$0.66	—	COM	14141R101
—	DYAX CORP	79,613	$1.52M	0.1%	$19.09	—	COM	26746E103
—	ADVAXIS INC	1,460	$1.494M	0.1%	—	—	Call	007624908
OCUL	OCULAR THERAPEUTIX INC	105,190	$1.479M	0.1%	$24.55	-18.1%	COM	67576A100
—	TROVAGENE INC	2,600	$1.479M	0.1%	—	—	Call	897238909
—	SYNERGY PHARMACEUTICALS INC	2,785	$1.476M	0.1%	—	—	Call	871639908
—	PUMA BIOTECHNOLOGY INC	195	$1.47M	0.1%	—	—	Call	74587V907
—	DYNAVAX TECHNOLOGIES CORP	594	$1.458M	0.1%	—	—	Put	268158951
MNOV	MEDICINOVA ORD SHS	500,000	$1.42M	0.1%	$3.41	0.0%	COM	58468P206
—	INSMED INC	764	$1.419M	0.1%	—	—	Put	457669957
—	DISCOVERY LABORATORIES INC.	4,703,551	$1.411M	0.1%	$0.30	—	COM	254668403
SRNE	SORRENTO THERAPEUTICS INC	167,064	$1.402M	0.1%	$15.93	0.0%	COM	83587F202
—	ABEONA THERAPEUTICS INC	340,702	$1.38M	0.1%	$4.52	—	COM	00289Y107
—	T2 BIOSYSTEMS INC	154,521	$1.354M	0.1%	$14.48	—	COM	89853L104
—	OCERA THERAPEUTICS INC	426,544	$1.348M	0.1%	$5.87	—	COM	67552A108
—	RELYPSA INC	69,980	$1.295M	0.1%	$18.51	—	COM	759531106
—	ADAMAS PHARMACEUTICALS INC	76,717	$1.284M	0.1%	$16.74	—	COM	00548A106
ABBV	ABBVIE INC	23,516	$1.28M	0.1%	$42.52	0.0%	COM	00287Y109
PCRX	PACIRA PHARMACEUTICALS INC	31,100	$1.278M	0.1%	$61.25	0.0%	COM	695127100
—	ANTARES PHARMA INC	722,567	$1.228M	0.1%	$1.70	—	COM	036642106
—	ENDOLOGIX INC	100,000	$1.226M	0.1%	$12.26	—	COM	29266S106
—	ANTHERA PHARMACEUTICALS INC	2,000	$1.218M	0.1%	—	—	Call	03674U901
—	VASCULAR SOLUTIONS INC	37,296	$1.209M	0.0%	$32.42	—	COM	92231M109
—	NEWLINK GENETICS CORP	33,658	$1.206M	0.0%	$35.83	—	COM	651511107
—	CYCLACEL PHARMACEUTICALS INC	2,356,091	$1.202M	0.0%	$0.86	—	COM	23254L306
—	ANACOR PHARMACEUTICALS INC	100	$1.177M	0.0%	—	—	Call	032420901
—	ANACOR PHARMACEUTICALS INC	100	$1.177M	0.0%	—	—	Put	032420951
—	POZEN INC	200,000	$1.167M	0.0%	$5.83	—	COM	73941U102
PVCT	PROVECTUS BIOPHARMACEUTICALS INC	1,982,137	$1.14M	0.0%	$0.82	-37.2%	COM	74373P108
—	TROVAGENE INC	200,000	$1.138M	0.0%	$5.69	—	COM	897238309
—	HALOZYME THERAPEUTICS INC	840	$1.128M	0.0%	—	—	Put	40637H959
—	CHINA JO-JO DRUGSTORES INC	614,149	$1.118M	0.0%	$1.82	—	COM	16949A206
—	GALENA BIOPHARMA INC	6,832	$1.081M	0.0%	—	—	Put	363256958
REEMF	RARE ELEMENT RESOURCES LTD	3,843,873	$1.08M	0.0%	$0.63	-40.1%	COM	75381M102
—	CELLECTAR BIOSCIENCES INC	653,712	$1.079M	0.0%	$0.61	—	*W	15117F112
—	SAGE THERAPEUTICS INC	251	$1.062M	0.0%	—	—	Call	78667J908
—	ALLIQUA BIOMEDICAL INC	330,128	$1.047M	0.0%	$4.13	—	COM	019621200
—	VTV THERAPEUTICS INC	160,556	$1.047M	0.0%	$6.52	—	CL A	918385105
—	HEARTWARE INTERNATIONAL INC	199	$1.041M	0.0%	—	—	Put	422368950
—	INOTEK PHARMACEUTICALS CORP	110,000	$1.034M	0.0%	$9.40	—	COM	45780V102
—	INTREXON CORP	325	$1.034M	0.0%	—	—	Call	46122T902
—	AMICUS THERAPEUTICS INC	730	$1.021M	0.0%	—	—	Call	03152W909
—	CAPRICOR THERAPEUTICS INC	250,450	$1.014M	0.0%	$5.05	—	COM	14070B101
—	EXELIXIS INC	1,783	$1M	0.0%	—	—	Call	30161Q904
—	CYTORI THERAPEUTICS INC	2,941,880	$1M	0.0%	$0.56	—	COM	23283K105
—	ARIAD PHARMACEUTICALS INC	169,000	$987K	0.0%	$7.38	—	COM	04033A100
—	ARIAD PHARMACEUTICALS INC	1,690	$987K	0.0%	—	—	Put	04033A950
BCRX	BIOCRYST PHARMACEUTICALS INC	86,395	$985K	0.0%	$13.34	0.0%	COM	09058V103
—	INSMED INC	511	$949K	0.0%	—	—	Call	457669907
—	ZAFGEN INC	296	$946K	0.0%	—	—	Put	98885E953
—	DEPOMED INC	50,000	$943K	0.0%	$18.86	—	COM	249908104
—	ANACOR PHARMACEUTICALS INC	8,000	$942K	0.0%	$117.75	—	COM	032420101
—	NEVRO CORP	203	$942K	0.0%	—	—	Call	64157F903
NTRA	NATERA ORD SHS	86,523	$939K	0.0%	$16.90	0.0%	COM	632307104
—	HEARTWARE INTERNATIONAL INC	17,500	$915K	0.0%	$52.29	—	COM	422368100
—	GW PHARMACEUTICALS PLC	100	$914K	0.0%	—	—	Call	36197T903
CSBR	CHAMPIONS ONCOLOGY ORD SHS	169,397	$893K	0.0%	$6.08	0.0%	COM	15870P307
—	PORTOLA PHARMACEUTICALS INC	206	$878K	0.0%	—	—	Put	737010958
—	ADVAXIS INC	85,700	$877K	0.0%	$10.23	—	COM	007624208
—	ADVAXIS INC	852	$872K	0.0%	—	—	Put	007624958
—	TONIX PHARMACEUTICALS HOLDING CORP	1,631	$863K	0.0%	—	—	Call	890260901
—	IDERA PHARMACEUTICALS INC	2,558	$857K	0.0%	—	—	Call	45168K906
—	STEMCELLS INC	2,039,122	$856K	0.0%	$1.21	—	COM	85857R204
—	SYNERGY PHARMACEUTICALS INC	1,613	$855K	0.0%	—	—	Put	871639958
—	CYNAPSUS THERAPEUTICS INC	52,169	$845K	0.0%	$16.22	—	COM	23257Y859
—	AQUINOX PHARMACEUTICALS INC	60,000	$844K	0.0%	$14.07	—	COM	03842B101
—	CTI BIOPHARMA CORP	5,747	$839K	0.0%	—	—	Call	12648L906
—	TONIX PHARMACEUTICALS HOLDING CORP	158,140	$837K	0.0%	$4.38	—	COM	890260201
—	MOMENTA PHARMACEUTICALS INC	50,030	$821K	0.0%	$16.41	—	COM	60877T100
—	EDAP TMS SA	1,466	$819K	0.0%	—	—	Put	268311957
—	RADIUS HEALTH INC	11,600	$804K	0.0%	$69.31	—	COM	750469207
—	TESARO INC	20,000	$802K	0.0%	$40.10	—	COM	881569107
—	TESARO INC	200	$802K	0.0%	—	—	Put	881569957
ALDX	ALDEYRA THERAPEUTICS INC	134,997	$787K	0.0%	$8.62	-9.4%	COM	01438T106
—	CYTOKINETICS INC	1,176	$787K	0.0%	—	—	Put	23282W955
—	ZS PHARMA INC	11,875	$780K	0.0%	$52.40	—	COM	98979G105
—	NEUROMETRIX INC	873,454	$771K	0.0%	$1.35	—	COM	641255302
—	BELLICUM PHARMACEUTICALS INC	526	$764K	0.0%	—	—	Call	079481907
—	CELLECTAR BIOSCIENCES INC	381,172	$751K	0.0%	$2.31	—	COM	15117F203
—	MELA SCIENCES INC.	657,860	$750K	0.0%	$1.21	—	COM	55277R308
—	SUNEDISON INC	1,000	$718K	0.0%	—	—	Call	86732Y909
—	EYEGATE PHARMACEUTICALS INC	243,790	$695K	0.0%	$2.85	—	COM	30233M107
—	TRANSITION THERAPEUTICS INC	382,600	$685K	0.0%	$5.35	—	COM	893716209
—	VIGGLE INC.	812,687	$666K	0.0%	$2.05	—	COM	92672V204
—	DBV TECHNOLOGIES S A	18,541	$660K	0.0%	$35.60	—	ADR	23306J101
—	ZOSANO PHARMA INC	163,365	$647K	0.0%	$9.59	—	COM	98979H103
—	COLLABRX ORD SHS	920,375	$635K	0.0%	$1.07	—	COM	19422J108
PTCT	PTC THERAPEUTICS INC	23,387	$624K	0.0%	$42.77	0.0%	COM	69366J200
—	TETRAPHASE PHARMACEUTICALS INC.	81,185	$606K	0.0%	$7.46	—	COM	88165N105
—	OVASCIENCE INC	692	$588K	0.0%	—	—	Call	69014Q901
—	CYMABAY THERAPEUTICS INC	293,294	$569K	0.0%	$3.61	—	COM	23257D103
—	OPHTHOTECH CORP	140	$567K	0.0%	—	—	Call	683745903
ESPR	ESPERION THERAPEUTICS INC	23,990	$566K	0.0%	$62.76	0.0%	COM	29664W105
—	RELYPSA INC	300	$555K	0.0%	—	—	Call	759531906
—	LEXICON PHARMACEUTICALS INC	510	$548K	0.0%	—	—	Call	528872902
ALNY	ALNYLAM PHARMACEUTICALS INC	6,809	$547K	0.0%	$111.10	0.0%	COM	02043Q107
—	ENTEROMEDICS INC	2,063,336	$536K	0.0%	$0.55	—	COM	29365M208
REGN	REGENERON PHARMACEUTICALS INC	1,150	$535K	0.0%	$534.07	0.0%	COM	75886F107
—	BIOTIE THERAPIES OYJ	40,000	$524K	0.0%	$13.10	—	ADR	09074D103
—	FIBROGEN INC	23,597	$517K	0.0%	$26.58	—	COM	31572Q808
—	SUPERCONDUCTOR TECHNOLOGIES INC	796,934	$494K	0.0%	$1.37	—	COM	867931404
—	FLUIDIGM CORP DEL	3,617	$488K	0.0%	—	—	Call	34385P908
—	SYNERGY PHARMACEUTICALS EQUITY WARRANTS	291,206	$486K	0.0%	$1.23	—	*W	871639118
—	PROGENICS PHARMACEUTICALS INC	840	$480K	0.0%	—	—	Call	743187906
—	ARBUTUS BIOPHARMA CORP	787	$479K	0.0%	—	—	Call	03879J900
—	PORTOLA PHARMACEUTICALS INC	11,201	$477K	0.0%	$42.59	—	COM	737010108
—	BELLICUM PHARMACEUTICALS INC	325	$472K	0.0%	—	—	Put	079481957
—	ANTARES PHARMA INC	2,742	$466K	0.0%	—	—	Call	036642906
OMER	OMEROS CORP	42,377	$464K	0.0%	$15.57	0.0%	COM	682143102
—	MEI PHARMA ORD SHS	295,491	$464K	0.0%	$5.18	—	COM	55279B202
—	IDERA PHARMACEUTICALS INC	137,700	$461K	0.0%	$3.41	—	COM	45168K306
—	NOVO NORDISK A/S SHS	84	$456K	0.0%	—	—	Put	670100955
—	CASTLIGHT HEALTH INC	1,065	$447K	0.0%	—	—	Call	14862Q900
—	BIODELIVERY SCIENCES INTERNATIONAL INC	789	$439K	0.0%	—	—	Put	09060J956
—	AVALANCHE BIOTECHNOLOGIES INC	530	$437K	0.0%	—	—	Call	05337G907
—	BIODEL INC	983,670	$433K	0.0%	$1.16	—	COM	09064M204
—	MERRIMACK PHARMACEUTICALS INC	500	$426K	0.0%	—	—	Call	590328900
—	INTREXON CORP	134	$426K	0.0%	—	—	Put	46122T952
—	UNIQURE B.V.	208	$425K	0.0%	—	—	Put	N90064951
—	NEVRO CORP	9,066	$421K	0.0%	$46.44	—	COM	64157F103
—	ELEVEN BIOTHERAPEUTICS INC	171,541	$413K	0.0%	$2.41	—	COM	286221106
—	VITAL THERAPIES INC	1,000	$404K	0.0%	—	—	Put	92847R954
—	AERIE PHARMACEUTICALS INC	215	$381K	0.0%	—	—	Call	00771V908
—	ROCKWELL MEDICAL INC	494	$381K	0.0%	—	—	Put	774374952
—	CYTRX ORD SHS	159,584	$378K	0.0%	$2.37	—	COM	232828509
—	IDERA PHARMACEUTICALS INC	1,111	$372K	0.0%	—	—	Put	45168K956
—	ROCKWELL MEDICAL INC	46,469	$358K	0.0%	$10.91	—	COM	774374102
—	PERSEON EQUITY WARRANTS	1,743,292	$355K	0.0%	$0.20	—	*W	715270112
—	AFFIMED N V	56,773	$350K	0.0%	$6.16	—	COM	N01045108
GMED	GLOBUS MEDICAL INC	16,700	$345K	0.0%	$25.33	0.0%	CL A	379577208
PRQR	PROQR THERAPEUTICS N V	21,950	$320K	0.0%	$16.02	+4.5%	SHS	N71542109
—	ZELTIQ AESTHETICS INC	10,000	$320K	0.0%	$32.00	—	COM	98933Q108
—	PTC THERAPEUTICS INC	119	$318K	0.0%	—	—	Put	69366J950
—	OXIGENE INC	328,431	$305K	0.0%	$1.30	—	COM	691828404
—	ACELRX PHARMACEUTICALS INC	98,602	$301K	0.0%	$3.86	—	COM	00444T100
—	NANOSPHERE ORD SHS	181,946	$297K	0.0%	$3.13	—	COM	63009F204
—	VALEANT PHARMACEUTICALS INTERNATIONAL INC	16	$285K	0.0%	—	—	Put	91911K952
—	LEXICON PHARMACEUTICALS INC	260	$279K	0.0%	—	—	Put	528872952
—	CONATUS PHARMACEUTICALS INC	62,500	$278K	0.0%	$5.15	—	COM	20600T108
—	PIERIS PHARMACEUTICALS INC	150,708	$276K	0.0%	$1.83	—	COM	720795103
—	AXOVANT SCIENCES ORD SHS	21,053	$272K	0.0%	$12.92	—	COM	G0750W104
—	RAPTOR PHARMACEUTICAL CORP	436	$264K	0.0%	—	—	Put	75382F956
ALKS	ALKERMES PLC	537	$260K	0.0%	—	—	Call	G01767105
—	NEURODERM LTD	12,416	$257K	0.0%	$20.70	—	ORD	M74231107
—	BIODELIVERY SCIENCES INTERNATIONAL INC	458	$255K	0.0%	—	—	Call	09060J906
—	BIOLASE INC	283,231	$255K	0.0%	$2.02	—	COM	090911108
INFIQ	INFINITY PHARMACEUTICALS INC	30,000	$254K	0.0%	$9.22	0.0%	COM	45665G303
—	INFINITY PHARMACEUTICALS INC	300	$254K	0.0%	—	—	Put	45665G953
—	CELLDEX THERAPEUTICS INC	238	$251K	0.0%	—	—	Put	15117B953
—	AVALANCHE BIOTECHNOLOGIES INC	300	$247K	0.0%	—	—	Put	05337G957
—	IMMUNE DESIGN CORP	20,000	$244K	0.0%	$12.20	—	COM	45252L103
—	MACROGENICS INC	114	$244K	0.0%	—	—	Call	556099909
—	CASI PHARMACEUTICALS ORD SHS	202,536	$217K	0.0%	—	—	COM	14757U109
—	AMARIN CORPORATION PLC	1,118	$216K	0.0%	—	—	Put	023111906
—	PEREGRINE PHARMACEUTICALS INC	10,907	$215K	0.0%	$22.68	—	COM	713661304
—	LPATH INC.	1,086,171	$213K	0.0%	$1.02	—	COM	548910306
—	VALEANT PHARMACEUTICALS INTERNATIONAL INC	1,171	$209K	0.0%	$178.48	—	COM	91911K102
—	EYEGATE PHARMACEUTICALS WARRANTS	200,000	$204K	0.0%	$1.02	—	*W	30233M115
—	APPLIED DNA SCIENCES EQUITY WARRANTS	63,310	$196K	0.0%	$1.06	—	*W	03815U110
—	PERSEON INC	569,985	$177K	0.0%	$0.31	—	COM	715270203
—	MANNKIND CORP	53,800	$173K	0.0%	$5.53	—	COM	56400P201
—	OCULAR THERAPEUTIX INC	115	$162K	0.0%	—	—	Call	67576A900
—	EXELIXIS INC	280	$157K	0.0%	—	—	Put	30161Q954
—	VITAL THERAPIES INC	38,700	$156K	0.0%	$4.03	—	COM	92847R104
—	INSPIREMD ORD SHS	927,876	$153K	0.0%	$0.66	—	COM	45779A309
—	HEAT BIOLOGICS ORD SHS	32,201	$149K	0.0%	$6.36	—	COM	42237K102
—	BENITEC BIOPHARMA LTD	391,826	$143K	0.0%	$0.36	—	*W	082053117
—	SKYSTAR BIO PHARMACEUTICAL	147,926	$141K	0.0%	$4.19	—	COM	830884300
—	CELSION CORPORATION	76,805	$128K	0.0%	$2.43	—	COM	15117N404
—	ACTINIUM PHARMACEUTICALS INC	68,427	$121K	0.0%	$1.77	—	COM	00507W107
—	SANGAMO BIOSCIENCES INC	215	$121K	0.0%	—	—	Call	800677906
—	ENDOCYTE INC	26,423	$121K	0.0%	$4.58	—	COM	29269A102
ADAPY	ADAPTIMMUNE THERAPEUTICS PLC	10,004	$120K	0.0%	$12.00	—	ADR	00653A107
—	HISTOGENICS CORP	27,505	$110K	0.0%	$11.00	—	COM	43358V109
—	VITAL THERAPIES INC	250	$101K	0.0%	—	—	Call	92847R904
—	CELSION CORPORATION	546	$91,000	0.0%	—	—	Put	15117N954
—	APRICUS BIOSCIENCES INC SHS	605	$88,000	0.0%	—	—	Put	03832V959
ORMP	ORAMED PHARMACEUTICALS INC	10,558	$58,000	0.0%	$6.38	-8.1%	COM	68403P203
—	ACELRX PHARMACEUTICALS INC	186	$57,000	0.0%	—	—	Put	00444T950
—	KERYX BIOPHARMACEUTICALS INC	158	$56,000	0.0%	—	—	Put	492515951
—	PLURISTEM THERAPEUTICS INC	292	$53,000	0.0%	—	—	Put	72940R952
—	ACELRX PHARMACEUTICALS INC	172	$52,000	0.0%	—	—	Call	00444T900
—	INTELLIPHARMACEUTICS INTERNATIONAL INC	187	$47,000	0.0%	—	—	Put	458173951
—	OPEXA THERAPEUTICS EQUITY WARRANTS	382,765	$46,000	0.0%	$0.17	—	*W	68372T129
—	XOMA CORP	500	$38,000	0.0%	—	—	Call	98419J907
—	CHINA MOBILE LIMITED	481	$19,000	0.0%	—	—	Call	16941M909
—	APRICUS BIOSCIENCES INC SHS	12,176	$18,000	0.0%	$1.72	—	COM	03832V109
—	BIO PATH HOLDINGS INC	14,873	$17,000	0.0%	$1.15	—	COM	09057N102
—	BIODEL INC	182	$8,000	0.0%	—	—	Put	09064M954