Location: Miami Beach, FL
CIK: 0001535610 · Show all filings
Period: Q3 2015 (← Previous) (Next →)
Filing Date: Nov 16, 2015
Total Value: $2.427B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | SPDR S&P 500 ETF TRUST | 16,250 | $307M | 12.6% | $18878.34 | — | — | Put | 78462F953 |
| — | ISHARES RUSSELL 2000 ETF | 25,500 | $273M | 11.3% | $10710.71 | — | — | Put | 464287955 |
| — | ELI LILLY & CO | 21,855 | $183M | 7.5% | $8368.98 | — | — | Call | 532457908 |
| — | GILEAD SCIENCES INC | 9,896 | $97.17M | 4.0% | $9819.02 | — | — | Call | 375558903 |
| — | BIOGEN IDEC INC | 3,090 | $90.17M | 3.7% | $29180.91 | — | — | Call | 09062X903 |
| — | GILEAD SCIENCES INC | 4,973 | $48.83M | 2.0% | $9819.02 | — | — | Put | 375558953 |
| — | MEDICINES CO | 11,749 | $44.6M | 1.8% | $3795.98 | — | — | Call | 584688905 |
| — | ZOGENIX INC | 31,115 | $42.01M | 1.7% | $1349.99 | — | — | Call | 98978L904 |
| — | BIOGEN IDEC INC | 1,419 | $41.41M | 1.7% | $29181.11 | — | — | Put | 09062X953 |
| — | ABBVIE INC | 7,456 | $40.57M | 1.7% | $5440.99 | — | — | Call | 00287Y909 |
| IWM | ISHARES RUSSELL 2000 ETF | 327,168 | $35.73M | 1.5% | $109.20 | $109.20 | — | ETF | 464287655 |
| — | EDWARDS LIFESCIENCES CORP | 1,682 | $34.9M | 1.4% | $20746.73 | — | — | Put | 28176E958 |
| — | BIOMARIN PHARMACEUTICAL INC | 2,911 | $30.66M | 1.3% | $10532.12 | — | — | Put | 09061G951 |
| — | TENET HEALTHCARE CORP | 7,745 | $28.59M | 1.2% | $3692.06 | — | — | Call | 88033G907 |
| — | BIOMARIN PHARMACEUTICAL INC | 2,375 | $25.01M | 1.0% | $10532.21 | — | — | Call | 09061G901 |
| — | GW PHARMACEUTICALS PLC | 2,712 | $24.78M | 1.0% | $9137.17 | — | — | Put | 36197T953 |
| — | MOBILEYE N.V. | 5,158 | $23.46M | 1.0% | $4548.08 | — | — | Put | N51488957 |
| — | MYLAN N.V. | 5,756 | $23.17M | 1.0% | $4026.06 | — | — | Put | N59465959 |
| BIIB | BIOGEN IDEC INC | 78,629 | $22.95M | 0.9% | $291.81 * | $330.23 | 0.0% | COM | 09062X103 |
| — | SAREPTA THERAPEUTICS INC | 6,671 | $21.42M | 0.9% | $3211.06 | — | — | Call | 803607900 |
| — | ELI LILLY & CO | 2,438 | $20.4M | 0.8% | $8369.16 | — | — | Put | 532457958 |
| — | SPDR SERIES TRUST | 3,144 | $19.57M | 0.8% | $6224.87 | — | — | Put | 78464A950 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 174,073 | $18.33M | 0.8% | $105.32 * | $133.58 | 0.0% | COM | 09061G101 |
| — | BRISTOL MYERS SQUIBB CO | 3,073 | $18.19M | 0.7% | $5919.95 | — | — | Call | 110122908 |
| — | ALEXION PHARMACEUTICALS INC | 975 | $15.25M | 0.6% | $15638.97 | — | — | Put | 015351959 |
| — | MYLAN N.V. | 376,827 | $15.17M | 0.6% | $40.26 | $40.26 | — | SHS | N59465109 |
| — | PIONEER NATURAL RESOURCE INC | 123,600 | $15.04M | 0.6% | $121.64 | $132.16 | — | COM | 723787107 |
| — | PIONEER NATURAL RESOURCE INC | 1,236 | $15.04M | 0.6% | $12164.24 | — | — | Put | 723787957 |
| — | GLOBAL BLOOD THERAPEUTICS INC | 342,857 | $14.46M | 0.6% | $42.16 | $42.16 | — | COM | 37890U108 |
| — | ALNYLAM PHARMACEUTICALS INC | 1,676 | $13.47M | 0.6% | $8035.80 | — | — | Call | 02043Q907 |
| — | NEWLINK GENETICS CORP | 3,701 | $13.26M | 0.5% | $3583.90 | — | — | Call | 651511907 |
| — | ABBVIE INC | 2,272 | $12.36M | 0.5% | $5441.02 | — | — | Put | 00287Y959 |
| — | APPLE INC | 1,110 | $12.24M | 0.5% | $11029.73 | — | — | Call | 037833900 |
| — | UNITED THERAPEUTICS CORP | 918 | $12.05M | 0.5% | $13124.18 | — | — | Call | 91307C902 |
| — | INTEROIL CORP | 3,356 | $11.31M | 0.5% | $3370.98 | — | — | Put | 460951956 |
| — | INTEROIL CORP | 328,705 | $11.08M | 0.5% | $33.71 | $45.11 | — | COM | 460951106 |
| EW | EDWARDS LIFESCIENCES CORP | 77,255 | $10.98M | 0.5% | $142.17 * | $23.77 | +1.5% | COM | 28176E108 |
| — | TENET HEALTHCARE CORP | 2,907 | $10.73M | 0.4% | $3692.12 | — | — | Put | 88033G957 |
| — | MOBILEYE N.V. | 235,819 | $10.72M | 0.4% | $45.48 | $44.40 | — | ORD | N51488117 |
| — | HERON THERAPEUTICS INC | 4,223 | $10.3M | 0.4% | $2439.97 | — | — | Call | 427746902 |
| — | CEMPRA INC | 3,649 | $10.16M | 0.4% | $2784.05 | — | — | Call | 15130J909 |
| — | KITE PHARMA INC | 1,823 | $10.15M | 0.4% | $5567.75 | — | — | Put | 49803L959 |
| — | MANNKIND CORP | 30,930 | $9.929M | 0.4% | $321.02 | — | — | Call | 56400P901 |
| — | GEVO INC | 100,000 | $9.819M | 0.4% | $98.19 | $3.27 | — | COM | 374396208 |
| THC | TENET HEALTHCARE CORP | 245,938 | $9.08M | 0.4% | $36.92 * | $51.67 | 0.0% | COM | 88033G407 |
| — | ACORDA THERAPEUTICS INC NOTE 1.75% | 9,600,000 | $8.664M | 0.4% | $0.90 | $0.90 | — | NOTE | 00484MAA4 |
| — | AGIOS PHARMACEUTICALS INC | 1,173 | $8.28M | 0.3% | $7058.82 | — | — | Put | 00847X954 |
| — | REGULUS THERAPEUTIC INC | 12,127 | $7.931M | 0.3% | $654.00 | — | — | Call | 75915K901 |
| — | TENAX THERAPEUTICS INC | 2,604,660 | $7.892M | 0.3% | $3.03 | $3.82 | — | COM | 88032L100 |
| AGIO | AGIOS PHARMACEUTICALS INC | 109,521 | $7.731M | 0.3% | $70.59 * | $97.74 | 0.0% | COM | 00847X104 |
| — | ALEXION PHARMACEUTICALS INC | 49,397 | $7.725M | 0.3% | $156.39 | $164.23 | — | COM | 015351109 |
| — | EXACT SCIENCES CORP | 4,293 | $7.723M | 0.3% | $1798.98 | — | — | Put | 30063P955 |
| — | PERRIGO CO. PLC | 491 | $7.722M | 0.3% | $15727.09 | — | — | Call | G97822903 |
| — | KITE PHARMA INC | 137,099 | $7.634M | 0.3% | $55.68 | $55.82 | — | COM | 49803L109 |
| — | BLUEBIRD BIO INC | 889 | $7.605M | 0.3% | $8554.56 | — | — | Call | 09609G900 |
| — | ACADIA PHARMACEUTICALS INC | 2,259 | $7.471M | 0.3% | $3307.22 | — | — | Put | 004225958 |
| — | MEDICINES CO 1.375% | 5,000,000 | $7.278M | 0.3% | $1.46 | $1.19 | — | DBCV | 584688AC9 |
| — | MYLAN N.V. | 1,747 | $7.033M | 0.3% | $4025.76 | — | — | Call | N59465909 |
| — | TOKAI PHARMACEUTICALS ORD SHS | 654,283 | $6.772M | 0.3% | $10.35 | $10.93 | — | COM | 88907J107 |
| — | MANNKIND CORP | 20,875 | $6.701M | 0.3% | $321.01 | — | — | Put | 56400P951 |
| — | BLUEPRINT MEDICINES INC | 308,504 | $6.583M | 0.3% | $21.34 | $26.38 | — | COM | 09627Y109 |
| — | GW PHARMACEUTICALS PLC | 71,757 | $6.556M | 0.3% | $91.36 | $91.30 | — | ADS | 36197T103 |
| — | BIOMARIN PHARMACEUTICAL INC. NOTE .75% | 5,000,000 | $6.459M | 0.3% | $1.29 | $1.49 | — | NOTE | 09061GAE1 |
| — | ALNYLAM PHARMACEUTICALS INC | 789 | $6.34M | 0.3% | $8035.49 | — | — | Put | 02043Q957 |
| — | ANADARKO PETROLEUM CORP | 1,023 | $6.178M | 0.3% | $6039.10 | — | — | Put | 032511957 |
| — | ANADARKO PETROLEUM CORP | 102,300 | $6.178M | 0.3% | $60.39 | $76.10 | — | COM | 032511107 |
| — | NOVAVAX INC | 8,418 | $5.952M | 0.2% | $707.06 | — | — | Put | 670002954 |
| — | SAREPTA THERAPEUTICS INC | 1,836 | $5.895M | 0.2% | $3210.78 | — | — | Put | 803607950 |
| — | BARCLAYS BANK PLC | 450,500 | $5.861M | 0.2% | $13.01 | $11.18 | — | ETN | 06740C519 |
| — | SPARK THERAPEUTICS INC | 1,402 | $5.851M | 0.2% | $4173.32 | — | — | Call | 84652J903 |
| — | SPARK THERAPEUTICS INC | 1,379 | $5.755M | 0.2% | $4173.31 | — | — | Put | 84652J953 |
| — | THERAPEUTICSMD INC | 9,800 | $5.743M | 0.2% | $586.02 | — | — | Call | 88338N907 |
| — | NEUROCRINE BIOSCIENCES INC | 1,403 | $5.583M | 0.2% | $3979.33 | — | — | Call | 64125C909 |
| — | KONINKLIJKE PHILIPS N V | 2,374 | $5.569M | 0.2% | $2345.83 | — | — | Call | 500472903 |
| — | INTRA-CELLULAR THERAPIES INC | 1,378 | $5.518M | 0.2% | $4004.35 | — | — | Call | 46116X901 |
| — | OPKO HEALTH INC | 6,456 | $5.429M | 0.2% | $840.92 | — | — | Put | 68375N953 |
| — | HALOZYME THERAPEUTICS INC | 4,014 | $5.391M | 0.2% | $1343.05 | — | — | Call | 40637H909 |
| EXAS | EXACT SCIENCES CORP | 289,112 | $5.201M | 0.2% | $17.99 * | $22.97 | 0.0% | COM | 30063P105 |
| OPK | OPKO HEALTH INC | 615,157 | $5.173M | 0.2% | $8.41 * | $13.34 | -0.8% | COM | 68375N103 |
| LAB | FLUIDIGM CORP DEL | 628,260 | $5.095M | 0.2% | $8.11 * | $19.90 | -20.9% | COM | 34385P108 |
| — | DYNAVAX TECHNOLOGIES CORP | 2,073 | $5.087M | 0.2% | $2453.93 | — | — | Call | 268158901 |
| — | DEPOMED INC | 2,680 | $5.052M | 0.2% | $1885.07 | — | — | Call | 249908904 |
| — | GENOCEA BIOSCIENCES INC | 729,141 | $4.995M | 0.2% | $6.85 | $8.18 | — | COM | 372427104 |
| — | NIVALIS THERAPEUTICS INC | 384,734 | $4.99M | 0.2% | $12.97 | $15.15 | — | COM | 65481J109 |
| — | HCA HOLDINGS INC | 624 | $4.827M | 0.2% | $7735.58 | — | — | Call | 40412C901 |
| — | ACHILLION PHARMACEUTICALS INC | 6,916 | $4.779M | 0.2% | $691.01 | — | — | Call | 00448Q901 |
| — | ACADIA PHARMACEUTICALS INC | 1,438 | $4.755M | 0.2% | $3306.68 | — | — | Call | 004225908 |
| — | AVALANCHE BIOTECHNOLOGIES INC | 574,260 | $4.732M | 0.2% | $8.24 | $13.94 | — | COM | 05337G107 |
| — | CELLDEX THERAPEUTICS INC | 4,448 | $4.688M | 0.2% | $1053.96 | — | — | Call | 15117B903 |
| — | ISIS PHARMACEUTICALS INC | 1,159 | $4.685M | 0.2% | $4042.28 | — | — | Call | 464330909 |
| — | DERMIRA INC | 190,000 | $4.435M | 0.2% | $23.34 | $18.06 | — | COM | 24983L104 |
| GILD | GILEAD SCIENCES INC | 45,140 | $4.432M | 0.2% | $98.18 * | $77.50 | 0.0% | COM | 375558103 |
| ABUS | ARBUTUS BIOPHARMA CORP | 725,007 | $4.415M | 0.2% | $6.09 * | $8.87 | 0.0% | COM | 03879J100 |
| — | RAPTOR PHARMACEUTICAL CORP | 7,289 | $4.41M | 0.2% | $605.02 | — | — | Call | 75382F906 |
| — | NEUROCRINE BIOSCIENCES INC | 1,267 | $4.397M | 0.2% | $3470.40 | — | — | Put | 64125C959 |
| — | INOVIO PHARMACEUTICALS INC | 737,551 | $4.263M | 0.2% | $5.78 | $8.16 | — | COM | 45773H201 |
| — | ZS PHARMA INC | 640 | $4.202M | 0.2% | $6565.63 | — | — | Put | 98979G955 |
| — | ENDO INTERNATIONAL PLC | 601 | $4.164M | 0.2% | $6928.45 | — | — | Call | G30401906 |
| — | RADIUS HEALTH INC | 578 | $4.006M | 0.2% | $6930.80 | — | — | Call | 750469907 |
| HRTX | HERON THERAPEUTICS INC | 160,323 | $3.912M | 0.2% | $24.40 * | $33.33 | 0.0% | COM | 427746102 |
| — | CIDARA THERAPEUTICS | 306,044 | $3.893M | 0.2% | $12.72 | $13.97 | — | COM | 171757107 |
| — | OPKO HEALTH INC | 4,500 | $3.785M | 0.2% | $841.11 | — | — | Call | 68375N903 |
| — | NORTHWEST BIOTHERAPEUTICS INC | 6,042 | $3.776M | 0.2% | $624.96 | — | — | Put | 66737P950 |
| — | NOVAVAX INC | 527,040 | $3.726M | 0.2% | $7.07 | $7.07 | — | COM | 670002104 |
| — | TRANSENTERIX INC | 1,591,117 | $3.596M | 0.1% | $2.26 | $3.00 | — | COM | 89366M201 |
| NWBO | NORTHWEST BIOTHERAPEUTICS INC | 572,518 | $3.578M | 0.1% | $6.25 * | $9.01 | +3.8% | COM | 66737P600 |
| — | VERTEX PHARMACEUTICALS INC | 341 | $3.551M | 0.1% | $10413.49 | — | — | Call | 92532F900 |
| — | ENDO INTERNATIONAL PLC | 50,658 | $3.51M | 0.1% | $69.29 | $82.08 | — | SHS | G30401106 |
| — | BLUEBIRD BIO INC | 406 | $3.473M | 0.1% | $8554.19 | — | — | Put | 09609G950 |
| — | NEVRO CORP | 745 | $3.456M | 0.1% | $4638.93 | — | — | Put | 64157F953 |
| SKY | SKYLINE MEDICAL UNITS | 447,944 | $3.454M | 0.1% | $7.71 * | $3.15 | 0.0% | COM | 830830105 |
| — | INTEC PHARMA LTD | 613,910 | $3.438M | 0.1% | $5.60 | $5.60 | — | SHS | M53644106 |
| — | DYNAVAX TECHNOLOGIES CORP | 134,954 | $3.312M | 0.1% | $24.54 | $23.96 | — | COM | 268158201 |
| — | HORIZON PHARMA PLC | 1,658 | $3.286M | 0.1% | $1981.91 | — | — | Put | G4617B955 |
| — | HORIZON PHARMA PLC | 164,658 | $3.264M | 0.1% | $19.82 | $19.82 | — | SHS | G4617B105 |
| — | AMICUS THERAPEUTICS INC | 2,322 | $3.248M | 0.1% | $1398.79 | — | — | Put | 03152W959 |
| — | LION BIOTECHNOLOGIES INC | 561,894 | $3.237M | 0.1% | $5.76 | $10.32 | — | COM | 53619R102 |
| — | ZELTIQ AESTHETICS INC | 1,000 | $3.203M | 0.1% | $3203.00 | — | — | Call | 98933Q908 |
| AOXG | AOXING PHARMACEUTICAL INC | 2,134,054 | $3.158M | 0.1% | $1.48 * | $1.58 | 0.0% | COM | 03740A106 |
| VRTX | VERTEX PHARMACEUTICALS INC | 30,000 | $3.124M | 0.1% | $104.13 * | $128.47 | 0.0% | COM | 92532F100 |
| — | MOBILEYE N.V. | 686 | $3.12M | 0.1% | $4548.10 | — | — | Call | N51488907 |
| — | BENITEC BIOPHARMA LTD | 505,220 | $3.107M | 0.1% | $6.15 | $6.15 | — | ADR | 082053307 |
| — | PTC THERAPEUTICS INC | 1,161 | $3.1M | 0.1% | $2670.11 | — | — | Call | 69366J900 |
| — | ZAFGEN INC | 960 | $3.067M | 0.1% | $3194.79 | — | — | Call | 98885E903 |
| — | NEUROMETRIX EQUITY WARRANTS | 12,212,278 | $3.052M | 0.1% | $0.25 | $0.20 | — | *W | 641255138 |
| — | CEMPRA INC | 1,082 | $3.012M | 0.1% | $2783.73 | — | — | Put | 15130J959 |
| — | NOVAVAX INC | 4,018 | $2.841M | 0.1% | $707.07 | — | — | Call | 670002904 |
| — | COMMUNITY HEALTH SYSTEMS INC | 662 | $2.831M | 0.1% | $4276.44 | — | — | Put | 203668958 |
| LXRX | LEXICON PHARMACEUTICALS INC | 261,595 | $2.81M | 0.1% | $10.74 | $7.34 | +48.7% | COM | 528872302 |
| — | PLURISTEM THERAPEUTICS INC | 1,474,369 | $2.683M | 0.1% | $1.82 | $2.53 | — | COM | 72940R102 |
| — | MEDGENICS EQUITY WARRANTS | 1,453,640 | $2.544M | 0.1% | $1.75 | $1.00 | — | *W | 58436Q112 |
| — | OVASCIENCE INC | 297,955 | $2.53M | 0.1% | $8.49 | $2.26 | — | COM | 69014Q101 |
| — | FEI CO | 340 | $2.483M | 0.1% | $7302.94 | — | — | Call | 30241L909 |
| — | REGENERON PHARMACEUTICALS INC | 53 | $2.465M | 0.1% | $46509.43 | — | — | Put | 75886F957 |
| SGMO | SANGAMO BIOSCIENCES INC | 435,225 | $2.455M | 0.1% | $5.64 * | $13.76 | -40.1% | COM | 800677106 |
| — | REVANCE THERAPEUTICS INC | 815 | $2.425M | 0.1% | $2975.46 | — | — | Call | 761330909 |
| — | LIPOCINE INC | 201,409 | $2.383M | 0.1% | $11.83 | $8.58 | — | COM | 53630X104 |
| — | ALEXION PHARMACEUTICALS INC | 152 | $2.377M | 0.1% | $15638.16 | — | — | Call | 015351909 |
| — | LA JOLLA PHARMACEUTICAL CO | 85,011 | $2.362M | 0.1% | $27.78 | $27.78 | — | COM | 503459604 |
| — | REGULUS THERAPEUTIC INC | 356,504 | $2.332M | 0.1% | $6.54 | $14.53 | — | COM | 75915K101 |
| — | INOVIO PHARMACEUTICALS INC | 3,965 | $2.292M | 0.1% | $578.06 | — | — | Call | 45773H901 |
| — | TRANSENTERIX INC | 10,026 | $2.266M | 0.1% | $226.01 | — | — | Call | 89366M901 |
| — | INVIVO THERAPEUTICS HOLDINGS CORP | 2,608 | $2.248M | 0.1% | $861.96 | — | — | Call | 46186M909 |
| — | REDHILL BIOPHARMA LTD | 173,550 | $2.241M | 0.1% | $12.91 | $12.91 | — | ADS | 757468103 |
| — | PARATEK PHARMACEUTICALS INC | 117,046 | $2.224M | 0.1% | $19.00 | $22.22 | — | COM | 699374302 |
| — | IGNYTA ORD SHS | 252,974 | $2.221M | 0.1% | $8.78 | $8.13 | — | COM | 451731103 |
| — | BIOCRYST PHARMACEUTICALS INC | 1,929 | $2.199M | 0.1% | $1139.97 | — | — | Put | 09058V953 |
| — | PUMA BIOTECHNOLOGY INC | 288 | $2.17M | 0.1% | $7534.72 | — | — | Put | 74587V957 |
| — | CYTOKINETICS INC | 3,106 | $2.078M | 0.1% | $669.03 | — | — | Call | 23282W905 |
| — | REPROS THERAPEUTICS INC | 2,793 | $2.075M | 0.1% | $742.93 | — | — | Put | 76028H959 |
| — | MIRATI THERAPEUTICS INC | 60,000 | $2.065M | 0.1% | $34.42 | $34.42 | — | COM | 60468T105 |
| — | REPROS THERAPEUTICS INC | 2,777 | $2.063M | 0.1% | $742.89 | — | — | Call | 76028H909 |
| — | BIODELIVERY SCIENCES INTERNATIONAL INC | 368,641 | $2.05M | 0.1% | $5.56 | $6.44 | — | COM | 09060J106 |
| — | CEMPRA INC | 73,195 | $2.038M | 0.1% | $27.84 | $34.31 | — | COM | 15130J109 |
| — | VAPOR CORP DEL | 225,387 | $2.015M | 0.1% | $8.94 | $8.94 | — | UNIT | 922099502 |
| PBYI | PUMA BIOTECHNOLOGY INC | 26,704 | $2.012M | 0.1% | $75.34 * | $94.57 | 0.0% | COM | 74587V107 |
| — | RICEBRAN TECHNOLOGIES | 901,973 | $1.975M | 0.1% | $2.19 | $3.97 | — | COM | 762831204 |
| — | VASCULAR SOLUTIONS INC | 607 | $1.967M | 0.1% | $3240.53 | — | — | Put | 92231M959 |
| — | BRAINSTORM CELL THERAPEUTICS | 852,348 | $1.952M | 0.1% | $2.29 | $4.17 | — | COM | 10501E201 |
| — | ZS PHARMA INC | 297 | $1.95M | 0.1% | $6565.66 | — | — | Call | 98979G905 |
| — | DYAX CORP | 1,017 | $1.941M | 0.1% | $1908.55 | — | — | Put | 26746E953 |
| — | SERES THERAPEUTICS INC | 64,775 | $1.92M | 0.1% | $29.64 | $29.64 | — | COM | 81750R102 |
| — | SORRENTO THERAPEUTICS INC | 2,275 | $1.909M | 0.1% | $839.12 | — | — | Call | 83587F902 |
| — | GLOBUS MEDICAL INC | 913 | $1.886M | 0.1% | $2065.72 | — | — | Put | 379577958 |
| — | OVASCIENCE INC | 2,200 | $1.868M | 0.1% | $849.09 | — | — | Put | 69014Q951 |
| CYH | COMMUNITY HEALTH SYSTEMS INC | 43,397 | $1.856M | 0.1% | $42.77 * | $45.85 | 0.0% | COM | 203668108 |
| — | CESCA THERAPEUTICS INC. | 3,500,037 | $1.855M | 0.1% | $0.53 | $1.37 | — | COM | 157131103 |
| — | CHINA BIOLOGIC PRODUCTS INC | 20,000 | $1.796M | 0.1% | $89.80 | $96.15 | — | COM | 16938C106 |
| — | QUEST RESOURCE HOLDING | 3,148,401 | $1.795M | 0.1% | $0.57 | $1.62 | — | COM | 74836W104 |
| — | XTL BIOPHARMACEUTICALS | 1,149,886 | $1.794M | 0.1% | $1.56 | $2.30 | — | ADR | 98386D208 |
| — | FOAMIX PHARMACEUTICALS LTD | 243,361 | $1.784M | 0.1% | $7.33 | $9.14 | — | SHS | M46135105 |
| — | ONCOSEC MEDICAL INC | 340,169 | $1.752M | 0.1% | $5.15 | $6.33 | — | COM | 68234L207 |
| — | IMMUNOCELLULAR THERAPEUTICS | 4,169,243 | $1.751M | 0.1% | $0.42 | $0.48 | — | COM | 452536105 |
| ACUR | ACURA PHARMACEUTICALS INC | 743,603 | $1.747M | 0.1% | $2.35 * | $3.40 | 0.0% | COM | 00509L802 |
| — | BELLICUM PHARMACEUTICALS INC | 120,094 | $1.745M | 0.1% | $14.53 | $22.97 | — | COM | 079481107 |
| — | BARCLAYS BANK PLC | 1,334 | $1.736M | 0.1% | $1301.35 | — | — | Call | 06740C909 |
| — | UNIQURE B.V. | 844 | $1.726M | 0.1% | $2045.02 | — | — | Call | N90064901 |
| — | SAGE THERAPEUTICS INC | 40,019 | $1.694M | 0.1% | $42.33 | $61.55 | — | COM | 78667J108 |
| — | TOBIRA THERAPEUTICS INC | 174,943 | $1.69M | 0.1% | $9.66 | $9.66 | — | COM | 88883P101 |
| — | NUVASIVE INC | 35,000 | $1.688M | 0.1% | $48.23 | $48.23 | — | COM | 670704105 |
| — | INFINITY PHARMACEUTICALS INC | 1,971 | $1.665M | 0.1% | $844.75 | — | — | Call | 45665G903 |
| — | FORWARD PHARMA A/S | 70,000 | $1.649M | 0.1% | $23.56 | $25.94 | — | ADR | 34986J105 |
| — | AGIOS PHARMACEUTICALS INC | 233 | $1.645M | 0.1% | $7060.09 | — | — | Call | 00847X904 |
| — | MOMENTA PHARMACEUTICALS INC | 1,000 | $1.641M | 0.1% | $1641.00 | — | — | Call | 60877T900 |
| — | OMEROS CORP | 1,489 | $1.632M | 0.1% | $1096.04 | — | — | Call | 682143902 |
| — | APPLIED GENETIC TECHNOLOGIES CORP | 124,000 | $1.629M | 0.1% | $13.14 | $19.39 | — | COM | 03820J100 |
| — | AMARIN CORPORATION PLC | 8,183 | $1.579M | 0.1% | $192.96 | — | — | Call | 023111206 |
| — | ENDO INTERNATIONAL PLC | 224 | $1.552M | 0.1% | $6928.57 | — | — | Put | G30401956 |
| — | NUVASIVE INC | 320 | $1.543M | 0.1% | $4821.88 | — | — | Call | 670704905 |
| — | NEWLINK GENETICS CORP | 430 | $1.541M | 0.1% | $3583.72 | — | — | Put | 651511957 |
| — | CARDICA INC | 5,281,185 | $1.521M | 0.1% | $0.29 | $0.66 | — | COM | 14141R101 |
| — | DYAX CORP | 79,613 | $1.52M | 0.1% | $19.09 | $19.09 | — | COM | 26746E103 |
| — | ADVAXIS INC | 1,460 | $1.494M | 0.1% | $1023.29 | — | — | Call | 007624908 |
| OCUL | OCULAR THERAPEUTIX INC | 105,190 | $1.479M | 0.1% | $14.06 * | $24.55 | -18.1% | COM | 67576A100 |
| — | TROVAGENE INC | 2,600 | $1.479M | 0.1% | $568.85 | — | — | Call | 897238909 |
| — | SYNERGY PHARMACEUTICALS INC | 2,785 | $1.476M | 0.1% | $529.98 | — | — | Call | 871639908 |
| — | PUMA BIOTECHNOLOGY INC | 195 | $1.47M | 0.1% | $7538.46 | — | — | Call | 74587V907 |
| — | DYNAVAX TECHNOLOGIES CORP | 594 | $1.458M | 0.1% | $2454.55 | — | — | Put | 268158951 |
| MNOV | MEDICINOVA ORD SHS | 500,000 | $1.42M | 0.1% | $2.84 * | $3.41 | 0.0% | COM | 58468P206 |
| — | INSMED INC | 764 | $1.419M | 0.1% | $1857.33 | — | — | Put | 457669957 |
| — | DISCOVERY LABORATORIES INC. | 4,703,551 | $1.411M | 0.1% | $0.30 | $0.30 | — | COM | 254668403 |
| SRNE | SORRENTO THERAPEUTICS INC | 167,064 | $1.402M | 0.1% | $8.39 * | $15.93 | 0.0% | COM | 83587F202 |
| — | ABEONA THERAPEUTICS INC | 340,702 | $1.38M | 0.1% | $4.05 | $4.52 | — | COM | 00289Y107 |
| — | T2 BIOSYSTEMS INC | 154,521 | $1.354M | 0.1% | $8.76 | $14.48 | — | COM | 89853L104 |
| — | OCERA THERAPEUTICS INC | 426,544 | $1.348M | 0.1% | $3.16 | $5.87 | — | COM | 67552A108 |
| — | RELYPSA INC | 69,980 | $1.295M | 0.1% | $18.51 | $18.51 | — | COM | 759531106 |
| — | ADAMAS PHARMACEUTICALS INC | 76,717 | $1.284M | 0.1% | $16.74 | $16.74 | — | COM | 00548A106 |
| ABBV | ABBVIE INC | 23,516 | $1.28M | 0.1% | $54.43 * | $42.52 | 0.0% | COM | 00287Y109 |
| PCRX | PACIRA PHARMACEUTICALS INC | 31,100 | $1.278M | 0.1% | $41.09 * | $61.25 | 0.0% | COM | 695127100 |
| — | ANTARES PHARMA INC | 722,567 | $1.228M | 0.1% | $1.70 | $1.70 | — | COM | 036642106 |
| — | ENDOLOGIX INC | 100,000 | $1.226M | 0.1% | $12.26 | $12.26 | — | COM | 29266S106 |
| — | ANTHERA PHARMACEUTICALS INC | 2,000 | $1.218M | 0.1% | $609.00 | — | — | Call | 03674U901 |
| — | VASCULAR SOLUTIONS INC | 37,296 | $1.209M | 0.0% | $32.42 | $32.42 | — | COM | 92231M109 |
| — | NEWLINK GENETICS CORP | 33,658 | $1.206M | 0.0% | $35.83 | $35.83 | — | COM | 651511107 |
| — | CYCLACEL PHARMACEUTICALS INC | 2,356,091 | $1.202M | 0.0% | $0.51 | $0.86 | — | COM | 23254L306 |
| — | ANACOR PHARMACEUTICALS INC | 100 | $1.177M | 0.0% | $11770.00 | — | — | Put | 032420951 |
| — | ANACOR PHARMACEUTICALS INC | 100 | $1.177M | 0.0% | $11770.00 | — | — | Call | 032420901 |
| — | POZEN INC | 200,000 | $1.167M | 0.0% | $5.83 | $5.83 | — | COM | 73941U102 |
| PVCT | PROVECTUS BIOPHARMACEUTICALS INC | 1,982,137 | $1.14M | 0.0% | $0.58 * | $0.82 | -37.2% | COM | 74373P108 |
| — | TROVAGENE INC | 200,000 | $1.138M | 0.0% | $5.69 | $5.69 | — | COM | 897238309 |
| — | HALOZYME THERAPEUTICS INC | 840 | $1.128M | 0.0% | $1342.86 | — | — | Put | 40637H959 |
| — | CHINA JO-JO DRUGSTORES INC | 614,149 | $1.118M | 0.0% | $1.82 | $1.82 | — | COM | 16949A206 |
| — | GALENA BIOPHARMA INC | 6,832 | $1.081M | 0.0% | $158.23 | — | — | Put | 363256958 |
| REEMF | RARE ELEMENT RESOURCES LTD | 3,843,873 | $1.08M | 0.0% | $0.28 * | $0.63 | -40.1% | COM | 75381M102 |
| — | CELLECTAR BIOSCIENCES INC | 653,712 | $1.079M | 0.0% | $1.65 | $0.61 | — | *W | 15117F112 |
| — | SAGE THERAPEUTICS INC | 251 | $1.062M | 0.0% | $4231.08 | — | — | Call | 78667J908 |
| — | ALLIQUA BIOMEDICAL INC | 330,128 | $1.047M | 0.0% | $3.17 | $4.13 | — | COM | 019621200 |
| — | VTV THERAPEUTICS INC | 160,556 | $1.047M | 0.0% | $6.52 | $6.52 | — | CL A | 918385105 |
| — | HEARTWARE INTERNATIONAL INC | 199 | $1.041M | 0.0% | $5231.16 | — | — | Put | 422368950 |
| — | INOTEK PHARMACEUTICALS CORP | 110,000 | $1.034M | 0.0% | $9.40 | $9.40 | — | COM | 45780V102 |
| — | INTREXON CORP | 325 | $1.034M | 0.0% | $3181.54 | — | — | Call | 46122T902 |
| — | AMICUS THERAPEUTICS INC | 730 | $1.021M | 0.0% | $1398.63 | — | — | Call | 03152W909 |
| — | CAPRICOR THERAPEUTICS INC | 250,450 | $1.014M | 0.0% | $4.05 | $5.05 | — | COM | 14070B101 |
| — | CYTORI THERAPEUTICS INC | 2,941,880 | $1M | 0.0% | $0.34 | $0.56 | — | COM | 23283K105 |
| — | EXELIXIS INC | 1,783 | $1M | 0.0% | $560.85 | — | — | Call | 30161Q904 |
| — | ARIAD PHARMACEUTICALS INC | 169,000 | $987K | 0.0% | $5.84 | $7.38 | — | COM | 04033A100 |
| — | ARIAD PHARMACEUTICALS INC | 1,690 | $987K | 0.0% | $584.02 | — | — | Put | 04033A950 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 86,395 | $985K | 0.0% | $11.40 * | $13.34 | 0.0% | COM | 09058V103 |
| — | INSMED INC | 511 | $949K | 0.0% | $1857.14 | — | — | Call | 457669907 |
| — | ZAFGEN INC | 296 | $946K | 0.0% | $3195.95 | — | — | Put | 98885E953 |
| — | DEPOMED INC | 50,000 | $943K | 0.0% | $18.86 | $18.86 | — | COM | 249908104 |
| — | NEVRO CORP | 203 | $942K | 0.0% | $4640.39 | — | — | Call | 64157F903 |
| — | ANACOR PHARMACEUTICALS INC | 8,000 | $942K | 0.0% | $117.75 | $117.75 | — | COM | 032420101 |
| NTRA | NATERA ORD SHS | 86,523 | $939K | 0.0% | $10.85 * | $16.90 | 0.0% | COM | 632307104 |
| — | HEARTWARE INTERNATIONAL INC | 17,500 | $915K | 0.0% | $52.29 | $52.29 | — | COM | 422368100 |
| — | GW PHARMACEUTICALS PLC | 100 | $914K | 0.0% | $9140.00 | — | — | Call | 36197T903 |
| CSBR | CHAMPIONS ONCOLOGY ORD SHS | 169,397 | $893K | 0.0% | $5.27 * | $6.08 | 0.0% | COM | 15870P307 |
| — | PORTOLA PHARMACEUTICALS INC | 206 | $878K | 0.0% | $4262.14 | — | — | Put | 737010958 |
| — | ADVAXIS INC | 85,700 | $877K | 0.0% | $10.23 | $10.23 | — | COM | 007624208 |
| — | ADVAXIS INC | 852 | $872K | 0.0% | $1023.47 | — | — | Put | 007624958 |
| — | TONIX PHARMACEUTICALS HOLDING CORP | 1,631 | $863K | 0.0% | $529.12 | — | — | Call | 890260901 |
| — | IDERA PHARMACEUTICALS INC | 2,558 | $857K | 0.0% | $335.03 | — | — | Call | 45168K906 |
| — | STEMCELLS INC | 2,039,122 | $856K | 0.0% | $0.42 | $1.21 | — | COM | 85857R204 |
| — | SYNERGY PHARMACEUTICALS INC | 1,613 | $855K | 0.0% | $530.07 | — | — | Put | 871639958 |
| — | CYNAPSUS THERAPEUTICS INC | 52,169 | $845K | 0.0% | $16.20 | $16.22 | — | COM | 23257Y859 |
| — | AQUINOX PHARMACEUTICALS INC | 60,000 | $844K | 0.0% | $14.07 | $14.07 | — | COM | 03842B101 |
| — | CTI BIOPHARMA CORP | 5,747 | $839K | 0.0% | $145.99 | — | — | Call | 12648L906 |
| — | TONIX PHARMACEUTICALS HOLDING CORP | 158,140 | $837K | 0.0% | $5.29 | $4.38 | — | COM | 890260201 |
| — | MOMENTA PHARMACEUTICALS INC | 50,030 | $821K | 0.0% | $16.41 | $16.41 | — | COM | 60877T100 |
| — | EDAP TMS SA | 1,466 | $819K | 0.0% | $558.66 | — | — | Put | 268311957 |
| — | RADIUS HEALTH INC | 11,600 | $804K | 0.0% | $69.31 | $69.31 | — | COM | 750469207 |
| — | TESARO INC | 20,000 | $802K | 0.0% | $40.10 | $40.10 | — | COM | 881569107 |
| — | TESARO INC | 200 | $802K | 0.0% | $4010.00 | — | — | Put | 881569957 |
| — | CYTOKINETICS INC | 1,176 | $787K | 0.0% | $669.22 | — | — | Put | 23282W955 |
| ALDX | ALDEYRA THERAPEUTICS INC | 134,997 | $787K | 0.0% | $5.83 * | $8.62 | -9.4% | COM | 01438T106 |
| — | ZS PHARMA INC | 11,875 | $780K | 0.0% | $65.68 | $52.40 | — | COM | 98979G105 |
| — | NEUROMETRIX INC | 873,454 | $771K | 0.0% | $0.88 | $1.35 | — | COM | 641255302 |
| — | BELLICUM PHARMACEUTICALS INC | 526 | $764K | 0.0% | $1452.47 | — | — | Call | 079481907 |
| — | CELLECTAR BIOSCIENCES INC | 381,172 | $751K | 0.0% | $1.97 | $2.31 | — | COM | 15117F203 |
| — | MELA SCIENCES INC. | 657,860 | $750K | 0.0% | $1.14 | $1.21 | — | COM | 55277R308 |
| — | SUNEDISON INC | 1,000 | $718K | 0.0% | $718.00 | — | — | Call | 86732Y909 |
| — | EYEGATE PHARMACEUTICALS INC | 243,790 | $695K | 0.0% | $2.85 | $2.85 | — | COM | 30233M107 |
| — | TRANSITION THERAPEUTICS INC | 382,600 | $685K | 0.0% | $1.79 | $5.35 | — | COM | 893716209 |
| — | VIGGLE INC. | 812,687 | $666K | 0.0% | $0.82 | $2.05 | — | COM | 92672V204 |
| — | DBV TECHNOLOGIES S A | 18,541 | $660K | 0.0% | $35.60 | $35.60 | — | ADR | 23306J101 |
| — | ZOSANO PHARMA INC | 163,365 | $647K | 0.0% | $3.96 | $9.59 | — | COM | 98979H103 |
| — | COLLABRX ORD SHS | 920,375 | $635K | 0.0% | $0.69 | $1.07 | — | COM | 19422J108 |
| PTCT | PTC THERAPEUTICS INC | 23,387 | $624K | 0.0% | $26.68 * | $42.77 | 0.0% | COM | 69366J200 |
| — | TETRAPHASE PHARMACEUTICALS INC. | 81,185 | $606K | 0.0% | $7.46 | $7.46 | — | COM | 88165N105 |
| — | OVASCIENCE INC | 692 | $588K | 0.0% | $849.71 | — | — | Call | 69014Q901 |
| — | CYMABAY THERAPEUTICS INC | 293,294 | $569K | 0.0% | $1.94 | $3.61 | — | COM | 23257D103 |
| — | OPHTHOTECH CORP | 140 | $567K | 0.0% | $4050.00 | — | — | Call | 683745903 |
| ESPR | ESPERION THERAPEUTICS INC | 23,990 | $566K | 0.0% | $23.59 * | $62.76 | 0.0% | COM | 29664W105 |
| — | RELYPSA INC | 300 | $555K | 0.0% | $1850.00 | — | — | Call | 759531906 |
| — | LEXICON PHARMACEUTICALS INC | 510 | $548K | 0.0% | $1074.51 | — | — | Call | 528872902 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 6,809 | $547K | 0.0% | $80.33 * | $111.10 | 0.0% | COM | 02043Q107 |
| — | ENTEROMEDICS INC | 2,063,336 | $536K | 0.0% | $0.26 | $0.55 | — | COM | 29365M208 |
| REGN | REGENERON PHARMACEUTICALS INC | 1,150 | $535K | 0.0% | $465.22 * | $534.07 | 0.0% | COM | 75886F107 |
| — | BIOTIE THERAPIES OYJ | 40,000 | $524K | 0.0% | $13.10 | $13.10 | — | ADR | 09074D103 |
| — | FIBROGEN INC | 23,597 | $517K | 0.0% | $21.91 | $26.58 | — | COM | 31572Q808 |
| — | SUPERCONDUCTOR TECHNOLOGIES INC | 796,934 | $494K | 0.0% | $0.62 | $1.37 | — | COM | 867931404 |
| — | FLUIDIGM CORP DEL | 3,617 | $488K | 0.0% | $134.92 | — | — | Call | 34385P908 |
| — | SYNERGY PHARMACEUTICALS EQUITY WARRANTS | 291,206 | $486K | 0.0% | $1.67 | $1.23 | — | *W | 871639118 |
| — | PROGENICS PHARMACEUTICALS INC | 840 | $480K | 0.0% | $571.43 | — | — | Call | 743187906 |
| — | ARBUTUS BIOPHARMA CORP | 787 | $479K | 0.0% | $608.64 | — | — | Call | 03879J900 |
| — | PORTOLA PHARMACEUTICALS INC | 11,201 | $477K | 0.0% | $42.59 | $42.59 | — | COM | 737010108 |
| — | BELLICUM PHARMACEUTICALS INC | 325 | $472K | 0.0% | $1452.31 | — | — | Put | 079481957 |
| — | ANTARES PHARMA INC | 2,742 | $466K | 0.0% | $169.95 | — | — | Call | 036642906 |
| — | MEI PHARMA ORD SHS | 295,491 | $464K | 0.0% | $1.57 | $5.18 | — | COM | 55279B202 |
| OMER | OMEROS CORP | 42,377 | $464K | 0.0% | $10.95 * | $15.57 | 0.0% | COM | 682143102 |
| — | IDERA PHARMACEUTICALS INC | 137,700 | $461K | 0.0% | $3.35 | $3.41 | — | COM | 45168K306 |
| — | NOVO NORDISK A/S SHS | 84 | $456K | 0.0% | $5428.57 | — | — | Put | 670100955 |
| — | CASTLIGHT HEALTH INC | 1,065 | $447K | 0.0% | $419.72 | — | — | Call | 14862Q900 |
| — | BIODELIVERY SCIENCES INTERNATIONAL INC | 789 | $439K | 0.0% | $556.40 | — | — | Put | 09060J956 |
| — | AVALANCHE BIOTECHNOLOGIES INC | 530 | $437K | 0.0% | $824.53 | — | — | Call | 05337G907 |
| — | BIODEL INC | 983,670 | $433K | 0.0% | $0.44 | $1.16 | — | COM | 09064M204 |
| — | INTREXON CORP | 134 | $426K | 0.0% | $3179.10 | — | — | Put | 46122T952 |
| — | MERRIMACK PHARMACEUTICALS INC | 500 | $426K | 0.0% | $852.00 | — | — | Call | 590328900 |
| — | UNIQURE B.V. | 208 | $425K | 0.0% | $2043.27 | — | — | Put | N90064951 |
| — | NEVRO CORP | 9,066 | $421K | 0.0% | $46.44 | $46.44 | — | COM | 64157F103 |
| — | ELEVEN BIOTHERAPEUTICS INC | 171,541 | $413K | 0.0% | $2.41 | $2.41 | — | COM | 286221106 |
| — | VITAL THERAPIES INC | 1,000 | $404K | 0.0% | $404.00 | — | — | Put | 92847R954 |
| — | AERIE PHARMACEUTICALS INC | 215 | $381K | 0.0% | $1772.09 | — | — | Call | 00771V908 |
| — | ROCKWELL MEDICAL INC | 494 | $381K | 0.0% | $771.26 | — | — | Put | 774374952 |
| — | CYTRX ORD SHS | 159,584 | $378K | 0.0% | $2.37 | $2.37 | — | COM | 232828509 |
| — | IDERA PHARMACEUTICALS INC | 1,111 | $372K | 0.0% | $334.83 | — | — | Put | 45168K956 |
| — | ROCKWELL MEDICAL INC | 46,469 | $358K | 0.0% | $7.70 | $10.91 | — | COM | 774374102 |
| — | PERSEON EQUITY WARRANTS | 1,743,292 | $355K | 0.0% | $0.20 | $0.20 | — | *W | 715270112 |
| — | AFFIMED N V | 56,773 | $350K | 0.0% | $6.16 | $6.16 | — | COM | N01045108 |
| GMED | GLOBUS MEDICAL INC | 16,700 | $345K | 0.0% | $20.66 * | $25.33 | 0.0% | CL A | 379577208 |
| PRQR | PROQR THERAPEUTICS N V | 21,950 | $320K | 0.0% | $14.58 * | $16.02 | +4.5% | SHS | N71542109 |
| — | ZELTIQ AESTHETICS INC | 10,000 | $320K | 0.0% | $32.00 | $32.00 | — | COM | 98933Q108 |
| — | PTC THERAPEUTICS INC | 119 | $318K | 0.0% | $2672.27 | — | — | Put | 69366J950 |
| — | OXIGENE INC | 328,431 | $305K | 0.0% | $0.93 | $1.30 | — | COM | 691828404 |
| — | ACELRX PHARMACEUTICALS INC | 98,602 | $301K | 0.0% | $3.05 | $3.86 | — | COM | 00444T100 |
| — | NANOSPHERE ORD SHS | 181,946 | $297K | 0.0% | $1.63 | $3.13 | — | COM | 63009F204 |
| — | VALEANT PHARMACEUTICALS INTERNATIONAL INC | 16 | $285K | 0.0% | $17812.50 | — | — | Put | 91911K952 |
| — | LEXICON PHARMACEUTICALS INC | 260 | $279K | 0.0% | $1073.08 | — | — | Put | 528872952 |
| — | CONATUS PHARMACEUTICALS INC | 62,500 | $278K | 0.0% | $4.45 | $5.15 | — | COM | 20600T108 |
| — | PIERIS PHARMACEUTICALS INC | 150,708 | $276K | 0.0% | $1.83 | $1.83 | — | COM | 720795103 |
| — | AXOVANT SCIENCES ORD SHS | 21,053 | $272K | 0.0% | $12.92 | $12.92 | — | COM | G0750W104 |
| — | RAPTOR PHARMACEUTICAL CORP | 436 | $264K | 0.0% | $605.50 | — | — | Put | 75382F956 |
| ALKS | ALKERMES PLC | 537 | $260K | 0.0% | $484.17 | — | — | Call | G01767105 |
| — | NEURODERM LTD | 12,416 | $257K | 0.0% | $20.70 | $20.70 | — | ORD | M74231107 |
| — | BIOLASE INC | 283,231 | $255K | 0.0% | $0.90 | $2.02 | — | COM | 090911108 |
| — | BIODELIVERY SCIENCES INTERNATIONAL INC | 458 | $255K | 0.0% | $556.77 | — | — | Call | 09060J906 |
| INFIQ | INFINITY PHARMACEUTICALS INC | 30,000 | $254K | 0.0% | $8.47 * | $9.22 | 0.0% | COM | 45665G303 |
| — | INFINITY PHARMACEUTICALS INC | 300 | $254K | 0.0% | $846.67 | — | — | Put | 45665G953 |
| — | CELLDEX THERAPEUTICS INC | 238 | $251K | 0.0% | $1054.62 | — | — | Put | 15117B953 |
| — | AVALANCHE BIOTECHNOLOGIES INC | 300 | $247K | 0.0% | $823.33 | — | — | Put | 05337G957 |
| — | MACROGENICS INC | 114 | $244K | 0.0% | $2140.35 | — | — | Call | 556099909 |
| — | IMMUNE DESIGN CORP | 20,000 | $244K | 0.0% | $12.20 | $12.20 | — | COM | 45252L103 |
| — | CASI PHARMACEUTICALS ORD SHS | 202,536 | $217K | 0.0% | $1.07 | — | — | COM | 14757U109 |
| — | AMARIN CORPORATION PLC | 1,118 | $216K | 0.0% | $193.20 | — | — | Put | 023111906 |
| — | PEREGRINE PHARMACEUTICALS INC | 10,907 | $215K | 0.0% | $19.71 | $22.68 | — | COM | 713661304 |
| — | LPATH INC. | 1,086,171 | $213K | 0.0% | $0.20 | $1.02 | — | COM | 548910306 |
| — | VALEANT PHARMACEUTICALS INTERNATIONAL INC | 1,171 | $209K | 0.0% | $178.48 | $178.48 | — | COM | 91911K102 |
| — | EYEGATE PHARMACEUTICALS WARRANTS | 200,000 | $204K | 0.0% | $1.02 | $1.02 | — | *W | 30233M115 |
| — | APPLIED DNA SCIENCES EQUITY WARRANTS | 63,310 | $196K | 0.0% | $3.10 | $1.06 | — | *W | 03815U110 |
| — | PERSEON INC | 569,985 | $177K | 0.0% | $0.31 | $0.31 | — | COM | 715270203 |
| — | MANNKIND CORP | 53,800 | $173K | 0.0% | $3.22 | $5.53 | — | COM | 56400P201 |
| — | OCULAR THERAPEUTIX INC | 115 | $162K | 0.0% | $1408.70 | — | — | Call | 67576A900 |
| — | EXELIXIS INC | 280 | $157K | 0.0% | $560.71 | — | — | Put | 30161Q954 |
| — | VITAL THERAPIES INC | 38,700 | $156K | 0.0% | $4.03 | $4.03 | — | COM | 92847R104 |
| — | INSPIREMD ORD SHS | 927,876 | $153K | 0.0% | $0.16 | $0.66 | — | COM | 45779A309 |
| — | HEAT BIOLOGICS ORD SHS | 32,201 | $149K | 0.0% | $4.63 | $6.36 | — | COM | 42237K102 |
| — | BENITEC BIOPHARMA LTD | 391,826 | $143K | 0.0% | $0.36 | $0.36 | — | *W | 082053117 |
| — | SKYSTAR BIO PHARMACEUTICAL | 147,926 | $141K | 0.0% | $0.95 | $4.19 | — | COM | 830884300 |
| — | CELSION CORPORATION | 76,805 | $128K | 0.0% | $1.67 | $2.43 | — | COM | 15117N404 |
| — | SANGAMO BIOSCIENCES INC | 215 | $121K | 0.0% | $562.79 | — | — | Call | 800677906 |
| — | ACTINIUM PHARMACEUTICALS INC | 68,427 | $121K | 0.0% | $1.77 | $1.77 | — | COM | 00507W107 |
| — | ENDOCYTE INC | 26,423 | $121K | 0.0% | $4.58 | $4.58 | — | COM | 29269A102 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 10,004 | $120K | 0.0% | $12.00 | $12.00 | — | ADR | 00653A107 |
| — | HISTOGENICS CORP | 27,505 | $110K | 0.0% | $4.00 | $11.00 | — | COM | 43358V109 |
| — | VITAL THERAPIES INC | 250 | $101K | 0.0% | $404.00 | — | — | Call | 92847R904 |
| — | CELSION CORPORATION | 546 | $91,000 | 0.0% | $166.67 | — | — | Put | 15117N954 |
| — | APRICUS BIOSCIENCES INC SHS | 605 | $88,000 | 0.0% | $145.45 | — | — | Put | 03832V959 |
| ORMP | ORAMED PHARMACEUTICALS INC | 10,558 | $58,000 | 0.0% | $5.49 * | $6.38 | -8.1% | COM | 68403P203 |
| — | ACELRX PHARMACEUTICALS INC | 186 | $57,000 | 0.0% | $306.45 | — | — | Put | 00444T950 |
| — | KERYX BIOPHARMACEUTICALS INC | 158 | $56,000 | 0.0% | $354.43 | — | — | Put | 492515951 |
| — | PLURISTEM THERAPEUTICS INC | 292 | $53,000 | 0.0% | $181.51 | — | — | Put | 72940R952 |
| — | ACELRX PHARMACEUTICALS INC | 172 | $52,000 | 0.0% | $302.33 | — | — | Call | 00444T900 |
| — | INTELLIPHARMACEUTICS INTERNATIONAL INC | 187 | $47,000 | 0.0% | $251.34 | — | — | Put | 458173951 |
| — | OPEXA THERAPEUTICS EQUITY WARRANTS | 382,765 | $46,000 | 0.0% | $0.12 | $0.17 | — | *W | 68372T129 |
| — | XOMA CORP | 500 | $38,000 | 0.0% | $76.00 | — | — | Call | 98419J907 |
| — | CHINA MOBILE LIMITED | 481 | $19,000 | 0.0% | $39.50 | — | — | Call | 16941M909 |
| — | APRICUS BIOSCIENCES INC SHS | 12,176 | $18,000 | 0.0% | $1.48 | $1.72 | — | COM | 03832V109 |
| — | BIO PATH HOLDINGS INC | 14,873 | $17,000 | 0.0% | $1.14 | $1.15 | — | COM | 09057N102 |
| — | BIODEL INC | 182 | $8,000 | 0.0% | $43.96 | — | — | Put | 09064M954 |