RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q2 2016 (← Previous) (Next →)

Filing Date: Aug 15, 2016

Total Value: $722M (100.0% shares, 0.0% debt)

Holdings (32)

WVE WAVE LIFE SCIENCES LTD 20.3%

Value $147M Shares 7,088,651 Share Price $20.69 * Est. Cost/Share $15.68 Unrealized @ Report Date -0.7%

— ACHILLION PHARMACEUTICALS INC 13.0%

Value $93.86M Shares 12,033,220 Share Price $7.80 Est. Cost/Share $6.45 Unrealized @ Report Date —

— AXOVANT SCIENCES LTD 8.9%

Value $64.2M Shares 5,000,000 Share Price $12.84 Est. Cost/Share $20.38 Unrealized @ Report Date —

— AVEXIS INC 7.1%

Value $50.92M Shares 1,339,382 Share Price $38.02 Est. Cost/Share $27.24 Unrealized @ Report Date —

ACRS ACLARIS THERAPEUTICS INC 6.7%

Value $48.53M Shares 2,627,719 Share Price $18.47 * Est. Cost/Share $19.34 Unrealized @ Report Date +2.5%

— NEKTAR THERAPEUTICS 6.4%

Value $45.89M Shares 3,224,854 Share Price $14.23 Est. Cost/Share $13.76 Unrealized @ Report Date —

ASND ASCENDIS PHARMA A S 6.3%

Value $45.29M Shares 3,412,857 Share Price $13.27 Est. Cost/Share $16.15 Unrealized @ Report Date —

TGTX TG THERAPEUTICS INC 3.8%

Value $27.46M Shares 4,531,714 Share Price $6.06 * Est. Cost/Share $10.14 Unrealized @ Report Date -19.8%

ARDX ARDELYX INC 2.8%

Value $20.19M Shares 2,312,243 Share Price $8.73 * Est. Cost/Share $10.53 Unrealized @ Report Date -22.4%

— ZOGENIX INC 2.7%

Value $19.73M Shares 2,451,237 Share Price $8.05 Est. Cost/Share $13.45 Unrealized @ Report Date —

— VITAE PHARMACEUTICALS INC 2.4%

Value $16.99M Shares 1,575,000 Share Price $10.79 Est. Cost/Share $7.52 Unrealized @ Report Date —

— AIMMUNE THERAPEUTICS INC 1.9%

Value $13.99M Shares 1,292,940 Share Price $10.82 Est. Cost/Share $20.75 Unrealized @ Report Date —

— ALCOBRA LTD 1.9%

Value $13.62M Shares 3,032,911 Share Price $4.49 Est. Cost/Share $6.39 Unrealized @ Report Date —

— PROTEON THERAPEUTICS INC 1.8%

Value $13.06M Shares 1,626,931 Share Price $8.03 Est. Cost/Share $11.31 Unrealized @ Report Date —

— AQUINOX PHARMACEUTICALS INC 1.6%

Value $11.2M Shares 1,691,977 Share Price $6.62 Est. Cost/Share $13.76 Unrealized @ Report Date —

— STRONGBRIDGE BIOPHARMA PLC 1.5%

Value $10.65M Shares 2,675,338 Share Price $3.98 Est. Cost/Share $7.60 Unrealized @ Report Date —

NTRA NATERA INC 1.3%

Value $9.453M Shares 783,520 Share Price $12.06 * Est. Cost/Share $16.90 Unrealized @ Report Date -34.2%

— DIMENSION THERAPEUTICS INC 1.3%

Value $9.288M Shares 1,548,033 Share Price $6.00 Est. Cost/Share $10.25 Unrealized @ Report Date —

BCRX BIOCRYST PHARMACEUTICALS 1.2%

Value $8.491M Shares 2,989,795 Share Price $2.84 * Est. Cost/Share $9.58 Unrealized @ Report Date -67.6%

— DICERNA PHARMACEUTICALS INC 1.0%

Value $7.286M Shares 2,428,571 Share Price $3.00 Est. Cost/Share $28.25 Unrealized @ Report Date —

SGMO SANGAMO BIOSCIENCES INC 0.9%

Value $6.751M Shares 1,165,938 Share Price $5.79 * Est. Cost/Share $8.61 Unrealized @ Report Date -26.0%

— AGILE THERAPEUTICS INC 0.9%

Value $6.492M Shares 853,151 Share Price $7.61 Est. Cost/Share $6.21 Unrealized @ Report Date —

— TENAX THERAPEUTICS INC 0.8%

Value $6.118M Shares 2,389,700 Share Price $2.56 Est. Cost/Share $3.92 Unrealized @ Report Date —

— EIGER BIOPHARMACEUTICALS INC 0.8%

Value $5.781M Shares 291,700 Share Price $19.82 Est. Cost/Share $16.77 Unrealized @ Report Date —

ONC BEIGENE LTD 0.7%

Value $5.066M Shares 170,000 Share Price $29.80 Est. Cost/Share $29.31 Unrealized @ Report Date —

— CIDARA THERAPEUTICS INC 0.6%

Value $4.235M Shares 410,809 Share Price $10.31 Est. Cost/Share $13.98 Unrealized @ Report Date —

— AKARI THERAPEUTICS PLC 0.4%

Value $3.16M Shares 234,240 Share Price $13.49 Est. Cost/Share $24.00 Unrealized @ Report Date —

— AEGLEA BIOTHERAPEUTICS INC 0.4%

Value $2.535M Shares 521,550 Share Price $4.86 Est. Cost/Share $4.86 Unrealized @ Report Date —

— MERUS N V 0.3%

Value $1.898M Shares 237,599 Share Price $7.99 Est. Cost/Share $7.99 Unrealized @ Report Date —

— ZYNERBA PHARMACEUTICALS INC 0.2%

Value $1.736M Shares 253,468 Share Price $6.85 Est. Cost/Share $14.31 Unrealized @ Report Date —

— ARCA BIOPHARMA INC 0.2%

Value $1.632M Shares 562,693 Share Price $2.90 Est. Cost/Share $4.96 Unrealized @ Report Date —

— PRONAI THERAPEUTICS INC 0.0%

Value $59,000 Shares 29,719 Share Price $1.99 Est. Cost/Share $20.52 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	7,088,651	$147M	20.3%	$20.69 *	$15.68	-0.7%	SHS	Y95308105
—	ACHILLION PHARMACEUTICALS INC	12,033,220	$93.86M	13.0%	$7.80	$6.45	—	COM	00448Q201
—	AXOVANT SCIENCES LTD	5,000,000	$64.2M	8.9%	$12.84	$20.38	—	COM	G0750W104
—	AVEXIS INC	1,339,382	$50.92M	7.1%	$38.02	$27.24	—	COM	05366U100
ACRS	ACLARIS THERAPEUTICS INC	2,627,719	$48.53M	6.7%	$18.47 *	$19.34	+2.5%	COM	00461U105
—	NEKTAR THERAPEUTICS	3,224,854	$45.89M	6.4%	$14.23	$13.76	—	COM	640268108
ASND	ASCENDIS PHARMA A S	3,412,857	$45.29M	6.3%	$13.27	$16.15	—	SPONSORED ADR	04351P101
TGTX	TG THERAPEUTICS INC	4,531,714	$27.46M	3.8%	$6.06 *	$10.14	-19.8%	COM	88322Q108
ARDX	ARDELYX INC	2,312,243	$20.19M	2.8%	$8.73 *	$10.53	-22.4%	COM	039697107
—	ZOGENIX INC	2,451,237	$19.73M	2.7%	$8.05	$13.45	—	COM NEW	98978L204
—	VITAE PHARMACEUTICALS INC	1,575,000	$16.99M	2.4%	$10.79	$7.52	—	COM	92847N103
—	AIMMUNE THERAPEUTICS INC	1,292,940	$13.99M	1.9%	$10.82	$20.75	—	COM	00900T107
—	ALCOBRA LTD	3,032,911	$13.62M	1.9%	$4.49	$6.39	—	SHS	M2239P109
—	PROTEON THERAPEUTICS INC	1,626,931	$13.06M	1.8%	$8.03	$11.31	—	COM	74371L109
—	AQUINOX PHARMACEUTICALS INC	1,691,977	$11.2M	1.6%	$6.62	$13.76	—	COM	03842B101
—	STRONGBRIDGE BIOPHARMA PLC	2,675,338	$10.65M	1.5%	$3.98	$7.60	—	SHS USD	G85347105
NTRA	NATERA INC	783,520	$9.453M	1.3%	$12.06 *	$16.90	-34.2%	COM	632307104
—	DIMENSION THERAPEUTICS INC	1,548,033	$9.288M	1.3%	$6.00	$10.25	—	COM	25433V105
BCRX	BIOCRYST PHARMACEUTICALS	2,989,795	$8.491M	1.2%	$2.84 *	$9.58	-67.6%	COM	09058V103
—	DICERNA PHARMACEUTICALS INC	2,428,571	$7.286M	1.0%	$3.00	$28.25	—	COM	253031108
SGMO	SANGAMO BIOSCIENCES INC	1,165,938	$6.751M	0.9%	$5.79 *	$8.61	-26.0%	COM	800677106
—	AGILE THERAPEUTICS INC	853,151	$6.492M	0.9%	$7.61	$6.21	—	COM	00847L100
—	TENAX THERAPEUTICS INC	2,389,700	$6.118M	0.8%	$2.56	$3.92	—	COM	88032L100
—	EIGER BIOPHARMACEUTICALS INC	291,700	$5.781M	0.8%	$19.82	$16.77	—	COM	28249U105
ONC	BEIGENE LTD	170,000	$5.066M	0.7%	$29.80	$29.31	—	SPONSORED ADR	07725L102
—	CIDARA THERAPEUTICS INC	410,809	$4.235M	0.6%	$10.31	$13.98	—	COM	171757107
—	AKARI THERAPEUTICS PLC	234,240	$3.16M	0.4%	$13.49	$24.00	—	SPONSORED ADR	00972G108
—	AEGLEA BIOTHERAPEUTICS INC	521,550	$2.535M	0.4%	$4.86	$4.86	—	COM	00773J103
—	MERUS N V	237,599	$1.898M	0.3%	$7.99	$7.99	—	COM	N5749R100
—	ZYNERBA PHARMACEUTICALS INC	253,468	$1.736M	0.2%	$6.85	$14.31	—	COM	98986X109
—	ARCA BIOPHARMA INC	562,693	$1.632M	0.2%	$2.90	$4.96	—	COM PAR$.001	00211Y407
—	PRONAI THERAPEUTICS INC	29,719	$59,000	0.0%	$1.99	$20.52	—	COM	74346L101