RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q3 2016 (← Previous) (Next →)

Filing Date: Nov 14, 2016

Total Value: $969M (100.0% shares, 0.0% debt)

Holdings (30)

WVE WAVE LIFE SCIENCES PTE LTD 23.7%

Value $230M Shares 7,088,651 Share Price $32.47 * Est. Cost/Share $15.68 Unrealized @ Report Date +50.7%

— ACHILLION PHARMACEUTICALS INC 10.1%

Value $97.47M Shares 12,033,220 Share Price $8.10 Est. Cost/Share $6.45 Unrealized @ Report Date —

ASND ASCENDIS PHARMA A S 7.6%

Value $74M Shares 3,681,491 Share Price $20.10 Est. Cost/Share $16.44 Unrealized @ Report Date —

— AVEXIS INC 7.4%

Value $71.39M Shares 1,732,274 Share Price $41.21 Est. Cost/Share $30.41 Unrealized @ Report Date —

— AXOVANT SCIENCES LTD 7.2%

Value $70M Shares 5,000,000 Share Price $14.00 Est. Cost/Share $20.38 Unrealized @ Report Date —

— NEKTAR THERAPEUTICS 6.5%

Value $62.95M Shares 3,664,154 Share Price $17.18 Est. Cost/Share $14.17 Unrealized @ Report Date —

ARDX ARDELYX INC 4.4%

Value $42.26M Shares 3,266,045 Share Price $12.94 * Est. Cost/Share $10.51 Unrealized @ Report Date -0.4%

ACRS ACLARIS THERAPEUTICS INC 4.1%

Value $39.62M Shares 1,547,152 Share Price $25.61 * Est. Cost/Share $19.34 Unrealized @ Report Date +9.7%

TGTX TG THERAPEUTICS INC 3.7%

Value $35.84M Shares 4,631,114 Share Price $7.74 * Est. Cost/Share $10.06 Unrealized @ Report Date -36.1%

— MERUS N V 3.2%

Value $31.45M Shares 2,656,166 Share Price $11.84 Est. Cost/Share $13.32 Unrealized @ Report Date —

— AQUINOX PHARMACEUTICALS INC 3.0%

Value $29.29M Shares 2,191,977 Share Price $13.36 Est. Cost/Share $13.67 Unrealized @ Report Date —

— AIMMUNE THERAPEUTICS INC 2.0%

Value $19.39M Shares 1,292,940 Share Price $15.00 Est. Cost/Share $20.75 Unrealized @ Report Date —

— FOAMIX PHARMACEUTICALS LTD 1.7%

Value $16.85M Shares 1,820,138 Share Price $9.26 Est. Cost/Share $9.26 Unrealized @ Report Date —

PTGX PROTAGONIST THERAPEUTICS INC 1.6%

Value $15.94M Shares 754,411 Share Price $21.13 * Est. Cost/Share $13.67 Unrealized @ Report Date 0.0%

— PROTEON THERAPEUTICS INC 1.6%

Value $15.18M Shares 1,626,931 Share Price $9.33 Est. Cost/Share $11.31 Unrealized @ Report Date —

— DICERNA PHARMACEUTICALS INC 1.5%

Value $14.28M Shares 2,428,571 Share Price $5.88 Est. Cost/Share $28.25 Unrealized @ Report Date —

BCRX BIOCRYST PHARMACEUTICALS 1.4%

Value $13.19M Shares 2,989,795 Share Price $4.41 * Est. Cost/Share $9.58 Unrealized @ Report Date -58.3%

— STRONGBRIDGE BIOPHARMA PLC 1.3%

Value $13.06M Shares 2,501,667 Share Price $5.22 Est. Cost/Share $7.60 Unrealized @ Report Date —

— AUDENTES THERAPEUTICS INC 1.3%

Value $12.6M Shares 707,426 Share Price $17.81 Est. Cost/Share $17.81 Unrealized @ Report Date —

— DIMENSION THERAPEUTICS INC 1.3%

Value $12.37M Shares 1,548,033 Share Price $7.99 Est. Cost/Share $10.25 Unrealized @ Report Date —

— ACCELERON PHARMA INC 1.2%

Value $11.53M Shares 318,565 Share Price $36.19 Est. Cost/Share $36.19 Unrealized @ Report Date —

ARWR ARROWHEAD PHARMACEUTICALS INC 1.2%

Value $11.21M Shares 1,525,424 Share Price $7.35 * Est. Cost/Share $6.48 Unrealized @ Report Date 0.0%

— TENAX THERAPEUTICS INC 0.6%

Value $5.532M Shares 2,389,700 Share Price $2.31 Est. Cost/Share $3.92 Unrealized @ Report Date —

ONC BEIGENE LTD 0.5%

Value $5.238M Shares 170,000 Share Price $30.81 Est. Cost/Share $29.31 Unrealized @ Report Date —

— ALCOBRA LTD 0.5%

Value $5.051M Shares 2,044,756 Share Price $2.47 Est. Cost/Share $6.39 Unrealized @ Report Date —

— EIGER BIOPHARMACEUTICALS INC 0.5%

Value $4.743M Shares 354,200 Share Price $13.39 Est. Cost/Share $16.17 Unrealized @ Report Date —

SGMO SANGAMO BIOSCIENCES INC 0.4%

Value $4.164M Shares 899,438 Share Price $4.63 * Est. Cost/Share $8.61 Unrealized @ Report Date -40.9%

— AEGLEA BIOTHERAPEUTICS INC 0.2%

Value $2.155M Shares 336,134 Share Price $6.41 Est. Cost/Share $4.86 Unrealized @ Report Date —

— ARCA BIOPHARMA INC 0.2%

Value $1.476M Shares 521,606 Share Price $2.83 Est. Cost/Share $4.96 Unrealized @ Report Date —

— AKARI THERAPEUTICS PLC 0.1%

Value $970K Shares 114,039 Share Price $8.51 Est. Cost/Share $24.00 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
WVE	WAVE LIFE SCIENCES PTE LTD	7,088,651	$230M	23.7%	$32.47 *	$15.68	+50.7%	SHS	Y95308105
—	ACHILLION PHARMACEUTICALS INC	12,033,220	$97.47M	10.1%	$8.10	$6.45	—	COM	00448Q201
ASND	ASCENDIS PHARMA A S	3,681,491	$74M	7.6%	$20.10	$16.44	—	SPONSORED ADR	04351P101
—	AVEXIS INC	1,732,274	$71.39M	7.4%	$41.21	$30.41	—	COM	05366U100
—	AXOVANT SCIENCES LTD	5,000,000	$70M	7.2%	$14.00	$20.38	—	COM	G0750W104
—	NEKTAR THERAPEUTICS	3,664,154	$62.95M	6.5%	$17.18	$14.17	—	COM	640268108
ARDX	ARDELYX INC	3,266,045	$42.26M	4.4%	$12.94 *	$10.51	-0.4%	COM	039697107
ACRS	ACLARIS THERAPEUTICS INC	1,547,152	$39.62M	4.1%	$25.61 *	$19.34	+9.7%	COM	00461U105
TGTX	TG THERAPEUTICS INC	4,631,114	$35.84M	3.7%	$7.74 *	$10.06	-36.1%	COM	88322Q108
—	MERUS N V	2,656,166	$31.45M	3.2%	$11.84	$13.32	—	COM	98978L204
—	AQUINOX PHARMACEUTICALS INC	2,191,977	$29.29M	3.0%	$13.36	$13.67	—	COM	03842B101
—	AIMMUNE THERAPEUTICS INC	1,292,940	$19.39M	2.0%	$15.00	$20.75	—	COM	00900T107
—	FOAMIX PHARMACEUTICALS LTD	1,820,138	$16.85M	1.7%	$9.26	$9.26	—	SHS	M46135105
PTGX	PROTAGONIST THERAPEUTICS INC	754,411	$15.94M	1.6%	$21.13 *	$13.67	0.0%	COM	74366E102
—	PROTEON THERAPEUTICS INC	1,626,931	$15.18M	1.6%	$9.33	$11.31	—	COM	74371L109
—	DICERNA PHARMACEUTICALS INC	2,428,571	$14.28M	1.5%	$5.88	$28.25	—	COM	253031108
BCRX	BIOCRYST PHARMACEUTICALS	2,989,795	$13.19M	1.4%	$4.41 *	$9.58	-58.3%	COM	09058V103
—	STRONGBRIDGE BIOPHARMA PLC	2,501,667	$13.06M	1.3%	$5.22	$7.60	—	SHS USD	G85347105
—	AUDENTES THERAPEUTICS INC	707,426	$12.6M	1.3%	$17.81	$17.81	—	COM	05070R104
—	DIMENSION THERAPEUTICS INC	1,548,033	$12.37M	1.3%	$7.99	$10.25	—	COM	25433V105
—	ACCELERON PHARMA INC	318,565	$11.53M	1.2%	$36.19	$36.19	—	COM	00434H108
ARWR	ARROWHEAD PHARMACEUTICALS INC	1,525,424	$11.21M	1.2%	$7.35 *	$6.48	0.0%	COM	04280A100
—	TENAX THERAPEUTICS INC	2,389,700	$5.532M	0.6%	$2.31	$3.92	—	COM	88032L100
ONC	BEIGENE LTD	170,000	$5.238M	0.5%	$30.81	$29.31	—	SPONSORED ADR	07725L102
—	ALCOBRA LTD	2,044,756	$5.051M	0.5%	$2.47	$6.39	—	SHS	M2239P109
—	EIGER BIOPHARMACEUTICALS INC	354,200	$4.743M	0.5%	$13.39	$16.17	—	COM	28249U105
SGMO	SANGAMO BIOSCIENCES INC	899,438	$4.164M	0.4%	$4.63 *	$8.61	-40.9%	COM	800677106
—	AEGLEA BIOTHERAPEUTICS INC	336,134	$2.155M	0.2%	$6.41	$4.86	—	COM	00773J103
—	ARCA BIOPHARMA INC	521,606	$1.476M	0.2%	$2.83	$4.96	—	COM PAR$.001	00211Y407
—	AKARI THERAPEUTICS PLC	114,039	$970K	0.1%	$8.51	$24.00	—	SPONSORED ADR	00972G108