RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q1 2016 (← Previous) (Next →)

Filing Date: May 16, 2016

Total Value: $782M (100.0% shares, 0.0% debt)

Holdings (42)

WVE WAVE LIFE SCIENCES LTD 12.6%

Value $98.39M Shares 7,088,651 Est. Cost $15.68 Unrealized -10.8%

— ACHILLION PHARMACEUTICALS INC 11.9%

Value $92.9M Shares 12,033,220 Est. Cost $6.45 Unrealized —

— AXOVANT SCIENCES LTD 7.3%

Value $57.4M Shares 5,000,000 Est. Cost $20.38 Unrealized —

ACRS ACLARIS THERAPEUTICS INC 6.4%

Value $49.8M Shares 2,627,719 Est. Cost $19.34 Unrealized -1.2%

— NEKTAR THERAPEUTICS 5.6%

Value $43.71M Shares 3,178,854 Est. Cost $13.75 Unrealized —

ASND ASCENDIS PHARMA A S 5.1%

Value $40.09M Shares 2,161,366 Est. Cost $17.82 Unrealized —

TGTX TG THERAPEUTICS INC 4.9%

Value $38.61M Shares 4,531,714 Est. Cost $10.14 Unrealized -13.7%

— AVEXIS INC 4.7%

Value $37.09M Shares 1,361,582 Est. Cost $27.24 Unrealized —

CHRS COHERUS BIOSCIENCES INC 3.5%

Value $27.01M Shares 1,272,048 Est. Cost $14.11 Unrealized +16.1%

— ZOGENIX INC 2.9%

Value $22.65M Shares 2,451,237 Est. Cost $13.45 Unrealized —

— ARENA PHARMACEUTICAL S INC 2.4%

Value $18.45M Shares 9,364,105 Est. Cost $1.90 Unrealized —

ARDX ARDELYX INC 2.3%

Value $17.88M Shares 2,300,481 Est. Cost $10.53 Unrealized -6.5%

— AIMMUNE THERAPEUTICS INC 2.2%

Value $17.53M Shares 1,292,940 Est. Cost $20.75 Unrealized —

— CELATOR PHARMACEUTICALS INC 2.0%

Value $15.6M Shares 1,414,114 Est. Cost $11.03 Unrealized —

— AQUINOX PHARMACEUTICALS INC 1.9%

Value $14.92M Shares 1,691,977 Est. Cost $13.76 Unrealized —

— CIDARA THERAPEUTICS INC 1.9%

Value $14.91M Shares 1,174,219 Est. Cost $13.98 Unrealized —

SGMO SANGAMO BIOSCIENCES INC 1.7%

Value $13.38M Shares 2,212,036 Est. Cost $8.61 Unrealized -30.2%

— ACORDA THERAPEUTICS INC 1.7%

Value $13.18M Shares 498,159 Est. Cost $26.45 Unrealized —

— DICERNA PHARMACEUTICALS INC 1.7%

Value $13.02M Shares 2,428,571 Est. Cost $28.25 Unrealized —

— PROTEON THERAPEUTICS INC 1.6%

Value $12.59M Shares 1,626,931 Est. Cost $11.31 Unrealized —

— STRONGBRIDGE BIOPHARMA PLC 1.6%

Value $12.27M Shares 2,690,702 Est. Cost $7.60 Unrealized —

— DIMENSION THERAPEUTICS INC 1.5%

Value $12.12M Shares 1,548,033 Est. Cost $10.25 Unrealized —

— ALCOBRA LTD 1.5%

Value $11.49M Shares 3,032,911 Est. Cost $6.39 Unrealized —

— VITAE PHARMACEUTICALS INC 1.3%

Value $10.44M Shares 1,575,000 Est. Cost $7.52 Unrealized —

COLL COLLEGIUM PHARMACEUTICAL INC 1.1%

Value $8.831M Shares 486,557 Est. Cost $17.29 Unrealized +5.1%

BCRX BIOCRYST PHARMACEUTICALS 1.1%

Value $8.461M Shares 2,989,795 Est. Cost $9.58 Unrealized -53.7%

NTRA NATERA INC 1.0%

Value $7.459M Shares 783,520 Est. Cost $16.90 Unrealized -49.9%

— REGULUS THERAPEUTICS INC 0.9%

Value $7.243M Shares 1,045,119 Est. Cost $15.20 Unrealized —

— AGILE THERAPEUTICS INC 0.8%

Value $6.609M Shares 1,064,217 Est. Cost $6.21 Unrealized —

ONC BEIGENE LTD 0.6%

Value $4.983M Shares 170,000 Est. Cost $29.31 Unrealized —

— TENAX THERAPEUTICS INC 0.6%

Value $4.899M Shares 2,389,700 Est. Cost $3.92 Unrealized —

— EIGER BIOPHARMACEUTICALS INC 0.6%

Value $4.892M Shares 291,700 Est. Cost $16.77 Unrealized —

— ZYNERBA PHARMACEUTICALS INC 0.6%

Value $4.793M Shares 507,191 Est. Cost $14.31 Unrealized —

— PRONAI THERAPEUTICS INC 0.5%

Value $4.078M Shares 604,982 Est. Cost $20.52 Unrealized —

— APPLIED GENETIC TECHNOL CORP 0.4%

Value $3.3M Shares 236,059 Est. Cost $16.68 Unrealized —

— ARCA BIOPHARMA INC 0.3%

Value $2.7M Shares 778,211 Est. Cost $4.96 Unrealized —

— AKARI THERAPEUTICS PLC 0.3%

Value $2.598M Shares 257,721 Est. Cost $24.00 Unrealized —

— NIVALIS THERAPEUTICS INC 0.3%

Value $2.556M Shares 612,863 Est. Cost $15.15 Unrealized —

— NEURODERM LTD 0.3%

Value $2.043M Shares 144,671 Est. Cost $20.67 Unrealized —

— BLUEPRINT MEDICINES CORP 0.1%

Value $1.019M Shares 56,442 Est. Cost $26.49 Unrealized —

— DERMA SCIENCES INC 0.0%

Value $252K Shares 81,239 Est. Cost $4.57 Unrealized —

— AMPLIPHI BIOSCIENCES CORP 0.0%

Value $211K Shares 53,600 Est. Cost $3.95 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	7,088,651	$98.39M	12.6%	$15.68	-10.8%	SHS	Y95308105
—	ACHILLION PHARMACEUTICALS INC	12,033,220	$92.9M	11.9%	$6.45	—	COM	00448Q201
—	AXOVANT SCIENCES LTD	5,000,000	$57.4M	7.3%	$20.38	—	COM	G0750W104
ACRS	ACLARIS THERAPEUTICS INC	2,627,719	$49.8M	6.4%	$19.34	-1.2%	COM	00461U105
—	NEKTAR THERAPEUTICS	3,178,854	$43.71M	5.6%	$13.75	—	COM	640268108
ASND	ASCENDIS PHARMA A S	2,161,366	$40.09M	5.1%	$17.82	—	SPONSORED ADR	04351P101
TGTX	TG THERAPEUTICS INC	4,531,714	$38.61M	4.9%	$10.14	-13.7%	COM	88322Q108
—	AVEXIS INC	1,361,582	$37.09M	4.7%	$27.24	—	COM	05366U100
CHRS	COHERUS BIOSCIENCES INC	1,272,048	$27.01M	3.5%	$14.11	+16.1%	COM	19249H103
—	ZOGENIX INC	2,451,237	$22.65M	2.9%	$13.45	—	COM NEW	98978L204
—	ARENA PHARMACEUTICAL S INC	9,364,105	$18.45M	2.4%	$1.90	—	COM	040047102
ARDX	ARDELYX INC	2,300,481	$17.88M	2.3%	$10.53	-6.5%	COM	039697107
—	AIMMUNE THERAPEUTICS INC	1,292,940	$17.53M	2.2%	$20.75	—	COM	00900T107
—	CELATOR PHARMACEUTICALS INC	1,414,114	$15.6M	2.0%	$11.03	—	COM	15089R102
—	AQUINOX PHARMACEUTICALS INC	1,691,977	$14.92M	1.9%	$13.76	—	COM	03842B101
—	CIDARA THERAPEUTICS INC	1,174,219	$14.91M	1.9%	$13.98	—	COM	171757107
SGMO	SANGAMO BIOSCIENCES INC	2,212,036	$13.38M	1.7%	$8.61	-30.2%	COM	800677106
—	ACORDA THERAPEUTICS INC	498,159	$13.18M	1.7%	$26.45	—	COM	00484M106
—	DICERNA PHARMACEUTICALS INC	2,428,571	$13.02M	1.7%	$28.25	—	COM	253031108
—	PROTEON THERAPEUTICS INC	1,626,931	$12.59M	1.6%	$11.31	—	COM	74371L109
—	STRONGBRIDGE BIOPHARMA PLC	2,690,702	$12.27M	1.6%	$7.60	—	SHS USD	G85347105
—	DIMENSION THERAPEUTICS INC	1,548,033	$12.12M	1.5%	$10.25	—	COM	25433V105
—	ALCOBRA LTD	3,032,911	$11.49M	1.5%	$6.39	—	SHS	M2239P109
—	VITAE PHARMACEUTICALS INC	1,575,000	$10.44M	1.3%	$7.52	—	COM	92847N103
COLL	COLLEGIUM PHARMACEUTICAL INC	486,557	$8.831M	1.1%	$17.29	+5.1%	COM	19459J104
BCRX	BIOCRYST PHARMACEUTICALS	2,989,795	$8.461M	1.1%	$9.58	-53.7%	COM	09058V103
NTRA	NATERA INC	783,520	$7.459M	1.0%	$16.90	-49.9%	COM	632307104
—	REGULUS THERAPEUTICS INC	1,045,119	$7.243M	0.9%	$15.20	—	COM	75915K101
—	AGILE THERAPEUTICS INC	1,064,217	$6.609M	0.8%	$6.21	—	COM	00847L100
ONC	BEIGENE LTD	170,000	$4.983M	0.6%	$29.31	—	SPONSORED ADR	07725L102
—	TENAX THERAPEUTICS INC	2,389,700	$4.899M	0.6%	$3.92	—	COM	88032L100
—	EIGER BIOPHARMACEUTICALS INC	291,700	$4.892M	0.6%	$16.77	—	COM	28249U105
—	ZYNERBA PHARMACEUTICALS INC	507,191	$4.793M	0.6%	$14.31	—	COM	98986X109
—	PRONAI THERAPEUTICS INC	604,982	$4.078M	0.5%	$20.52	—	COM	74346L101
—	APPLIED GENETIC TECHNOL CORP	236,059	$3.3M	0.4%	$16.68	—	COM	03820J100
—	ARCA BIOPHARMA INC	778,211	$2.7M	0.3%	$4.96	—	COM PAR$.001	00211Y407
—	AKARI THERAPEUTICS PLC	257,721	$2.598M	0.3%	$24.00	—	SPONSORED ADR	00972G108
—	NIVALIS THERAPEUTICS INC	612,863	$2.556M	0.3%	$15.15	—	COM	65481J109
—	NEURODERM LTD	144,671	$2.043M	0.3%	$20.67	—	ORD SHS	M74231107
—	BLUEPRINT MEDICINES CORP	56,442	$1.019M	0.1%	$26.49	—	COM	09627Y109
—	DERMA SCIENCES INC	81,239	$252K	0.0%	$4.57	—	COM PAR $.01	249827502
—	AMPLIPHI BIOSCIENCES CORP	53,600	$211K	0.0%	$3.95	—	COM NEW	03211P202