Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	SPDR S&P 500 ETF TRUST	14,000	$303M	11.3%	—	—	Put	78462F953
—	ELI LILLY & CO	29,347	$236M	8.8%	—	—	Call	532457908
—	SPDR S&P 500 ETF TRUST	10,000	$216M	8.1%	—	—	Call	78462F903
—	ISHARES RUSSELL 2000	14,892	$185M	6.9%	—	—	Put	464287955
—	SAREPTA THERAPEUTICS INC	26,748	$164M	6.2%	—	—	Put	803607950
—	GILEAD SCIENCES INC	11,691	$92.5M	3.5%	—	—	Call	375558903
—	REGENERON PHARMACEUTICALS INC	1,792	$72.04M	2.7%	—	—	Put	75886F957
—	ISHARES RUSSELL 2000	5,441	$67.58M	2.5%	—	—	Call	464287905
—	HCA HOLDINGS INC	7,680	$58.08M	2.2%	—	—	Call	40412C901
—	MONSANTO CO	5,607	$57.3M	2.1%	—	—	Call	61166W901
—	AMGEN INC	2,569	$42.85M	1.6%	—	—	Put	031162900
—	ELI LILLY & CO	4,898	$39.31M	1.5%	—	—	Put	532457958
—	CELGENE CORP	3,451	$36.07M	1.4%	—	—	Call	151020904
SRPT	SAREPTA THERAPEUTICS INC	536,282	$32.93M	1.2%	$17.82	+69.6%	COM	803607100
REGN	REGENERON PHARMACEUTICALS INC	75,919	$30.52M	1.1%	$397.70	+0.3%	COM	75886F107
—	BRISTOL MYERS SQUIBB CO.	5,409	$29.16M	1.1%	—	—	Call	110122908
—	ALKERMES PLC	3,249	$28.2M	1.1%	—	—	Call	G01767905
—	MERCK & CO INC	4,487	$28M	1.0%	—	—	Call	58933Y905
—	ABBVIE INC	4,136	$26.09M	1.0%	—	—	Call	00287Y909
—	CELGENE CORP	2,415	$25.24M	0.9%	—	—	Put	151020954
—	ACADIA PHARMACEUTICALS INC	7,784	$24.76M	0.9%	—	—	Call	00404A909
AMGN	AMGEN INC	133,176	$22.21M	0.8%	$111.19	+14.9%	COM	031162100
—	AGIOS PHARMACEUTICALS INC	4,108	$21.7M	0.8%	—	—	Call	00847X904
—	SAREPTA THERAPEUTICS INC	3,526	$21.65M	0.8%	—	—	Call	803607900
—	ABBOTT LABORATORIES	5,000	$21.14M	0.8%	—	—	Put	002824950
—	CLOVIS ONCOLOGY INC	5,850	$21.09M	0.8%	—	—	Call	189464900
—	BIOGEN INC	667	$20.88M	0.8%	—	—	Call	09062X903
—	EXPRESS SCRIPTS HOLDING CO	2,897	$20.43M	0.8%	—	—	Call	30219G908
—	BRISTOL MYERS SQUIBB CO.	3,469	$18.7M	0.7%	—	—	Put	110122958
—	VERTEX PHARMACEUTICALS INC	1,955	$17.05M	0.6%	—	—	Call	92532F900
—	CEMPRA INC	6,323	$15.3M	0.6%	—	—	Put	15130J959
—	RETROPHIN INC	6,293	$14.08M	0.5%	—	—	Call	761299906
—	PUMA BIOTECHNOLOGY INC	2,021	$13.55M	0.5%	—	—	Call	74587V907
—	SHIRE PLC	698	$13.53M	0.5%	—	—	Put	82481R956
—	SHIRE PLC	698	$13.53M	0.5%	—	—	Call	82481R906
—	SPDR SERIES TRUST	1,958	$12.98M	0.5%	—	—	Put	78464A950
—	UNITED THERAPEUTICS CORP	1,098	$12.96M	0.5%	—	—	Put	91307C952
—	HUMANA INC	700	$12.38M	0.5%	—	—	Put	444859952
—	EXPRESS SCRIPTS HOLDING CO	1,691	$11.93M	0.4%	—	—	Put	30219G958
—	ASTRAZENECA PLC	3,520	$11.57M	0.4%	—	—	Call	046353908
—	LEXICON PHARMACEUTICALS INC	6,263	$11.32M	0.4%	—	—	Call	528872902
—	HESS CORP	2,059	$11.04M	0.4%	—	—	Call	42809H907
—	DEPOMED INC	4,321	$10.8M	0.4%	—	—	Call	249908904
—	MYLAN N.V.	2,804	$10.69M	0.4%	—	—	Call	N59465909
—	DYNAVAX TECHNOLOGIES CORP	9,984	$10.47M	0.4%	—	—	Call	268158901
—	ALNYLAM PHARMACEUTICALS INC	1,448	$9.815M	0.4%	—	—	Call	02043Q907
—	ONCOBIOLOGICS INC	2,268,585	$9.643M	0.4%	$3.48	—	COM	68235M105
—	BLUEBIRD BIO INC	1,380	$9.354M	0.4%	—	—	Call	09609G900
BMY	BRISTOL MYERS SQUIBB CO.	156,887	$8.459M	0.3%	$46.14	0.0%	COM	110122108
—	DYNAVAX TECHNOLOGIES CORP	7,628	$8.002M	0.3%	—	—	Put	268158951
—	IONIS PHARMACEUTICALS INC	2,171	$7.955M	0.3%	—	—	Call	462222900
—	CLOVIS ONCOLOGY INC	2,091	$7.538M	0.3%	—	—	Put	189464950
—	ABBVIE INC	1,178	$7.43M	0.3%	—	—	Put	00287Y959
—	HORIZON PHARMA PLC	4,088	$7.412M	0.3%	—	—	Call	G4617B905
—	ACHILLION PHARMACEUTICALS INC	9,039	$7.322M	0.3%	—	—	Call	00448Q901
—	CEMPRA INC	3,019	$7.306M	0.3%	—	—	Call	15130J909
—	TENET HEALTHCARE CORP	3,179	$7.204M	0.3%	—	—	Call	88033G907
—	AMICUS THERAPEUTICS INC	9,632	$7.128M	0.3%	—	—	Call	03152W909
—	DEXCOM INC	806	$7.065M	0.3%	—	—	Call	252131907
—	OPHTHOTECH CORP	1,517	$6.998M	0.3%	—	—	Call	683745903
—	EXELIXIS INC	5,392	$6.896M	0.3%	—	—	Put	30161Q954
—	KITE PHARMA INC	1,177	$6.575M	0.2%	—	—	Put	49803L959
—	AXOVANT SCIENCES LTD	4,680	$6.552M	0.2%	—	—	Call	G0750W904
—	LION BIOTECHNOLOGIES INC	7,901	$6.503M	0.2%	—	—	Put	53619R952
—	NEUROCRINE BIOSCIENCES INC	1,214	$6.148M	0.2%	—	—	Call	64125C909
—	GILEAD SCIENCES INC	771	$6.1M	0.2%	—	—	Put	375558953
—	KITE PHARMA INC	1,082	$6.044M	0.2%	—	—	Call	49803L909
—	SHIRE PLC	31,172	$6.043M	0.2%	$184.60	—	COM	82481R106
—	HALOZYME THERAPEUTICS INC	4,901	$5.92M	0.2%	—	—	Call	40637H909
—	ALNYLAM PHARMACEUTICALS INC	869	$5.89M	0.2%	—	—	Put	02043Q957
—	PTC THERAPEUTICS INC	3,989	$5.589M	0.2%	—	—	Call	69366J900
—	TENAX THERAPEUTICS INC	2,412,857	$5.55M	0.2%	$3.75	—	COM	88032L100
—	DYNAVAX TECHNOLOGIES CORP	521,875	$5.474M	0.2%	$15.82	—	COM	268158201
—	SAGE THERAPEUTICS INC	1,165	$5.365M	0.2%	—	—	Call	78667J908
—	HUMANA INC	278	$4.918M	0.2%	—	—	Call	444859902
—	LA JOLLA PHARMACEUTICAL CO	2,064	$4.91M	0.2%	—	—	Call	503459904
ABT	ABBOTT LABORATORIES	112,888	$4.774M	0.2%	$33.35	+8.3%	COM	002824100
—	AERIE PHARMACEUTICALS INC	1,180	$4.453M	0.2%	—	—	Call	00771V908
—	CYTRX CORP.	7,424,786	$4.368M	0.2%	$0.59	—	COM	232828509
—	SYNERGY PHARMACEUTICALS INC.	7,912	$4.36M	0.2%	—	—	Call	871639908
—	AMARIN CORPORATION PLC	13,648	$4.354M	0.2%	—	—	Call	023111906
—	MEDICINES CO	1,150	$4.34M	0.2%	—	—	Call	584688905
—	NEWLINK GENETICS CORP	2,887	$4.336M	0.2%	—	—	Call	651511907
—	PUMA BIOTECHNOLOGY INC	643	$4.311M	0.2%	—	—	Put	74587V957
—	ACORDA THERAPEUTICS INC 15 JUN 21 1.75%	5,100,000	$4.16M	0.2%	$0.90	—	NOTE	00484MAA4
—	TENET HEALTHCARE CORP	1,744	$3.952M	0.1%	—	—	Put	88033G957
—	CELGENE CORP	37,728	$3.944M	0.1%	$104.54	—	COM	151020104
—	MANNKIND CORP	62,303	$3.863M	0.1%	—	—	Put	56400P951
RGNX	REGENXBIO ORD SHS	263,177	$3.687M	0.1%	$14.34	-23.0%	COM	75901B107
—	REGULUS THERAPEUTIC INC	11,000	$3.63M	0.1%	—	—	Call	75915K901
—	GW PHARMACEUTICALS PLC	273	$3.624M	0.1%	—	—	Call	36197T903
—	CYTORI THERAPEUTICS INC.	1,762,846	$3.579M	0.1%	$2.09	—	COM	23283K204
—	NOVO NORDISK A/S	859	$3.573M	0.1%	—	—	Put	670100955
—	OPGEN INC.	2,161,467	$3.545M	0.1%	$1.55	—	COM	68373L109
—	TESARO INC	333	$3.338M	0.1%	—	—	Call	881569907
UTHR	UNITED THERAPEUTICS CORP	28,112	$3.319M	0.1%	$120.15	0.0%	COM	91307C102
—	ZOGENIX INC	1,228	$3.265M	0.1%	—	—	Call	98978L904
—	BIOGEN INC	100	$3.13M	0.1%	—	—	Put	09062X953
—	EIGER BIOPHARMACEUTICALS INC.	230,803	$3.09M	0.1%	$15.96	—	COM	28249U105
ABUS	ARBUTUS BIOPHARMA CORP	878,531	$3.022M	0.1%	$7.22	-45.9%	COM	03879J100
—	INTEC PHARMA LTD.	498,006	$2.898M	0.1%	$5.45	—	COM	M53644106
—	LA JOLLA PHARMACEUTICAL CO	120,964	$2.878M	0.1%	$20.85	—	COM	503459604
—	PIERIS PHARMACEUTICALS INC	1,543,307	$2.824M	0.1%	$1.64	—	COM	720795103
—	TESARO INC	27,500	$2.757M	0.1%	$100.25	—	COM	881569107
—	IONIS PHARMACEUTICALS INC	737	$2.7M	0.1%	—	—	Put	462222950
—	OPKO HEALTH INC	2,491	$2.638M	0.1%	—	—	Call	68375N903
—	SANGAMO BIOSCIENCES INC	5,611	$2.598M	0.1%	—	—	Call	800677906
THC	TENET HEALTHCARE CORP	112,831	$2.557M	0.1%	$26.03	0.0%	COM	88033G407
—	GW PHARMACEUTICALS PLC	192	$2.548M	0.1%	—	—	Put	36197T953
—	REGENERON PHARMACEUTICALS INC	63	$2.533M	0.1%	—	—	Call	75886F907
—	DURECT CORP	1,800,000	$2.502M	0.1%	$1.22	—	COM	266605104
—	EXELIXIS INC	1,930	$2.468M	0.1%	—	—	Call	30161Q904
—	DERMIRA INC	722	$2.442M	0.1%	—	—	Call	24983L904
—	HCA HOLDINGS INC	316	$2.39M	0.1%	—	—	Put	40412C951
—	SOPHIRIS BIO INC.	757,033	$2.354M	0.1%	$3.11	—	COM	83578Q209
—	ABBOTT LABORATORIES	555	$2.347M	0.1%	—	—	Call	002824900
—	DERMIRA INC	678	$2.293M	0.1%	—	—	Put	24983L954
—	PARATEK PHARMACEUTICALS INC	175,000	$2.277M	0.1%	$17.47	—	COM	699374302
—	VERTEX PHARMACEUTICALS INC	260	$2.267M	0.1%	—	—	Put	92532F950
—	BARCLAYS BANK PLC	65,000	$2.215M	0.1%	$34.08	—	IPATH	06740Q260
—	ENDO INTERNATIONAL PLC	1,096	$2.208M	0.1%	—	—	Put	G30401956
—	CIDARA THERAPEUTICS INC.	190,358	$2.18M	0.1%	$11.59	—	COM	171757107
—	NIVALIS THERAPEUTICS INC	267,650	$2.176M	0.1%	$11.19	—	COM	65481J109
—	OPKO HEALTH INC	2,027	$2.147M	0.1%	—	—	Put	68375N953
—	VERSARTIS INC.	174,968	$2.143M	0.1%	$12.25	—	COM	92529L102
—	EXACT SCIENCES CORP	1,153	$2.137M	0.1%	—	—	Put	30063P955
—	INSMED INC	1,459	$2.118M	0.1%	—	—	Call	457669907
—	SYNERGY PHARMACEUTICALS INC.	3,842	$2.117M	0.1%	—	—	Put	871639958
—	FORWARD PHARMA A/S	99,053	$2.08M	0.1%	$23.42	—	ADR	34986J105
—	VANDA PHARMACEUTICALS INC	1,247	$2.075M	0.1%	—	—	Call	921659908
—	LION BIOTECHNOLOGIES INC	246,342	$2.027M	0.1%	$8.51	—	COM	53619R102
—	REXAHN PHARMACEUTICALS INC	9,464,849	$1.988M	0.1%	$0.33	—	COM	761640101
—	PROTHENA CORPORATION PLC	325	$1.949M	0.1%	—	—	Call	G72800990
—	ACTINIUM PHARMACEUTICALS INC	1,382,629	$1.867M	0.1%	$1.35	—	COM	00507W107
—	FOAMIX PHARMACEUTICALS LTD	201,564	$1.866M	0.1%	$8.92	—	SHS	M46135105
—	BIODELIVERY SCIENCES INTERNATIONAL INC	689,900	$1.863M	0.1%	$4.78	—	COM	09060J106
—	BIO PATH HOLDINGS INC	1,314,692	$1.841M	0.1%	$1.99	—	COM	09057N102
EDIT	EDITAS MEDICINE INC.	135,000	$1.82M	0.1%	$20.49	0.0%	COM	28106W103
—	INSMED INC	1,247	$1.811M	0.1%	—	—	Put	457669957
—	AGENUS INC	2,500	$1.795M	0.1%	—	—	Put	00847G955
NTLA	INTELLIA THERAPEUTICS INC	104,841	$1.784M	0.1%	$19.36	0.0%	COM	45826J105
—	ACADIA PHARMACEUTICALS INC	548	$1.743M	0.1%	—	—	Put	00404A959
—	ZOGENIX INC	150,000	$1.715M	0.1%	$9.10	—	COM	98978L204
—	HEMISPHERX BIOPHARMA INC.	1,351,850	$1.69M	0.1%	$1.25	—	COM	42366C301
—	AMICUS THERAPEUTICS INC	2,282	$1.689M	0.1%	—	—	Put	03152W959
—	NEVRO CORP	161	$1.681M	0.1%	—	—	Call	64157F903
—	GLOBAL BLOOD THERAPEUTICS INC	721	$1.662M	0.1%	—	—	Call	37890U908
—	ADVERUM BIOTECHNOLOGIES	402,603	$1.655M	0.1%	$3.16	—	COM	00773U108
EDAP	EDAP TMS S A	545,918	$1.583M	0.1%	$3.31	—	ADR	268311107
—	CYTORI THERAPEUTICS INC.	895,017	$1.547M	0.1%	$0.79	—	*W	23283K121
—	CARDIOME PHARMA CORP	484,505	$1.521M	0.1%	$3.14	—	COM	14159U301
—	WAFERGEN BIO SYSTEMS INC.	1,578,616	$1.52M	0.1%	$0.77	—	COM	93041P308
—	FIBROGEN INC	72,669	$1.504M	0.1%	$21.29	—	COM	31572Q808
—	VISTAGEN THERAPEUTICS INC	349,096	$1.452M	0.1%	$3.90	—	COM	92840H202
—	ONCOSEC MEDICAL INC	834,004	$1.426M	0.1%	$2.99	—	COM	68234L207
—	IGNYTA INC	225,900	$1.421M	0.1%	$6.50	—	COM	451731103
—	MEDIGUS LTD	1,042,813	$1.373M	0.1%	$1.32	—	COM	58471G102
—	INOTEK PHARMACEUTICALS CORP	144,002	$1.365M	0.1%	$9.06	—	COM	45780V102
—	ACHILLION PHARMACEUTICALS INC	1,681	$1.362M	0.1%	—	—	Put	00448Q951
—	BIOBLAST PHARMA LTD	784,057	$1.356M	0.1%	$2.49	—	SHS	M20156101
—	ONCOBIOLOGICS INC	926,651	$1.332M	0.0%	$0.97	—	*W	68235M121
—	AXOVANT SCIENCES LTD	93,109	$1.304M	0.0%	$12.60	—	COM	G0750W104
—	THERAPEUTICSMD INC	1,910	$1.301M	0.0%	—	—	Call	88338N907
—	PRONAI THERAPEUTICS INC.	687,734	$1.252M	0.0%	$1.97	—	COM	74346L101
—	SAGE THERAPEUTICS INC	265	$1.22M	0.0%	—	—	Put	78667J958
—	ENDO INTERNATIONAL PLC	59,237	$1.194M	0.0%	$26.05	—	SHS	G30401106
—	ALCOBRA LTD	4,826	$1.192M	0.0%	—	—	Call	M2239P909
—	CAPRICOR THERAPEUTICS INC.	357,436	$1.183M	0.0%	$4.09	—	COM	14070B101
—	ACORDA THERAPEUTICS INC	563	$1.176M	0.0%	—	—	Put	00484M956
—	CHECK CAP LTD	585,569	$1.159M	0.0%	$1.98	—	SHS	M2361E112
—	BIOCRYST PHARMACEUTICALS INC	2,584	$1.14M	0.0%	—	—	Call	09058V903
—	ONCONOVA THERAPEUTICS INC	725,434	$1.124M	0.0%	$1.55	—	*W	68232V116
—	MANNKIND CORP	1,785,368	$1.107M	0.0%	$0.62	—	COM	56400P201
—	CELSION CORP.	894,406	$1.091M	0.0%	$1.28	—	COM	15117N404
—	LEXICON PHARMACEUTICALS INC	600	$1.084M	0.0%	—	—	Put	528872952
—	IMMUNOCELLULAR THERAPEUTICS	15,161,641	$1.077M	0.0%	$0.07	—	*W	452536113
—	RICEBRAN TECHNOLOGIES	794,436	$1.073M	0.0%	$3.65	—	COM	762831204
—	STEMLINE THERAPEUTICS INC	98,050	$1.062M	0.0%	$10.83	—	COM	85858C107
—	BRAINSTORM CELL THERAPEUTICS	444,500	$1.062M	0.0%	$4.17	—	COM	10501E201
—	OCERA THERAPEUTICS INC	400,035	$1.06M	0.0%	$5.54	—	COM	67552A108
—	PACIRA PHARMACEUTICALS INC	309	$1.057M	0.0%	—	—	Call	695127900
—	RADIUS HEALTH INC	195	$1.055M	0.0%	—	—	Call	750469907
—	CALITHERA BIOSCIENCES INC.	324,500	$1.055M	0.0%	$3.25	—	COM	13089P101
—	ONCONOVA THERAPEUTICS INC	392,023	$1.039M	0.0%	$2.65	—	COM	68232V306
—	ALLIQUA BIOMEDICAL INC	1,321,726	$1.031M	0.0%	$1.60	—	COM	019621200
—	CEL SCI CORP	3,372,642	$1.029M	0.0%	$0.46	—	COM	150837508
—	DRAGONWAVE INC.	378,338	$1.018M	0.0%	$2.69	—	COM	26144M400
—	VTV THERAPEUTICS INC	134,747	$969K	0.0%	$6.52	—	CL A	918385105
—	IMMUNOMEDICS INC.	297,310	$966K	0.0%	$68.00	—	COM	452907108
—	ONCOBIOLOGICS INC	902,050	$905K	0.0%	$0.76	—	*W	68235M113
CSBR	CHAMPIONS ONCOLOGY INC	538,593	$905K	0.0%	$4.47	-58.1%	COM	15870P307
—	RETROPHIN INC	401	$897K	0.0%	—	—	Put	761299956
—	NEURALSTEM INC.	2,787,745	$892K	0.0%	$0.29	—	COM	64127R302
—	INSPIREMD INC	29,594,500	$888K	0.0%	$0.03	—	*W	45779A119
—	REDHILL BIOPHARMA LTD	63,800	$888K	0.0%	$12.91	—	ADS	757468103
—	DEXTERA SURGICAL INC	450,507	$851K	0.0%	$1.80	—	COM	252366109
—	HORIZON PHARMA PLC	463	$839K	0.0%	—	—	Put	G4617B955
—	EYEGATE PHARMACEUTICALS INC	508,598	$834K	0.0%	$2.36	—	COM	30233M107
—	INTRA CELLULAR THERAPIES INC	533	$812K	0.0%	—	—	Call	46116X901
—	WINDTREE THERAPEUTICS INC.	310,000	$797K	0.0%	$1.93	—	COM	97382D105
—	MEDGENICS INC	141,977	$791K	0.0%	$5.55	—	COM	58436Q203
—	AMPLIPHI BIOSCIENCES CORP	521,378	$782K	0.0%	$1.55	—	COM	03211P202
—	RADIUS HEALTH INC	141	$763K	0.0%	—	—	Put	750469957
—	IMMUNOCELLULAR THERAPEUTICS	6,405,230	$756K	0.0%	$0.37	—	COM	452536105
—	XTL BIOPHARMACEUTICALS LTD	751,289	$714K	0.0%	$2.30	—	ADR	98386D208
—	GENVEC INC	1,510,377	$696K	0.0%	$0.57	—	COM	37246C307
—	PORTOLA PHARMACEUTICALS INC	300	$681K	0.0%	—	—	Call	737010908
—	FOAMIX PHARMACEUTICALS LTD	724	$670K	0.0%	—	—	Call	M46135905
—	ARBUTUS BIOPHARMA CORP	1,949	$670K	0.0%	—	—	Call	03879J900
—	SUPERCONDUCTOR TECHNOLOGIES INC.	250,474	$669K	0.0%	$2.67	—	COM	867931503
—	ANTHERA PHARMACEUTICALS INC	2,121	$668K	0.0%	—	—	Call	03674U901
—	MIRATI THERAPEUTICS INC.	99,735	$659K	0.0%	$6.61	—	COM	60468T105
—	PSIVIDA CORP	195,100	$587K	0.0%	$2.68	—	COM	74440J101
—	TENAX THERAPEUTICS INC	2,534	$583K	0.0%	—	—	Call	88032L900
ACUR	ACURA PHARMACEUTICALS INC	352,835	$565K	0.0%	$3.40	-47.9%	COM	00509L802
—	BLUEPRINT MEDICINES CORP	190	$564K	0.0%	—	—	Put	09627Y959
—	PACIRA PHARMACEUTICALS INC	159	$544K	0.0%	—	—	Put	695127950
—	ASSEMBLY BIOSCIENCES INC	75,200	$542K	0.0%	$5.56	—	COM	045396108
PARNEUR	PARNELL PHARMACEUTICALS HOLDINGS LTD	369,700	$532K	0.0%	$1.63	—	SHS	Q73622104
—	NEWLINK GENETICS CORP	34,561	$519K	0.0%	$32.40	—	COM	651511107
—	SUNSHINE HEART INC.	908,021	$518K	0.0%	$0.57	—	COM	86782U106
—	RENNOVA HEALTH INC	2,724,721	$516K	0.0%	$0.19	—	COM	759757107
—	STRATA SKIN SCIENCES INC	1,000,790	$510K	0.0%	$0.80	—	COM	86272A107
—	MEDICINES CO	13,508	$510K	0.0%	$35.59	—	COM	584688105
—	TESARO INC	50	$501K	0.0%	—	—	Put	881569957
—	TOKAI PHARMACEUTICALS INC.	321,600	$492K	0.0%	$5.61	—	COM	88907J107
—	BIODELIVERY SCIENCES INTERNATIONAL INC	1,770	$478K	0.0%	—	—	Call	09060J906
—	COMMUNITY HEALTH SYSTEMS INC	413	$477K	0.0%	—	—	Put	203668958
—	INOTEK PHARMACEUTICALS CORP	500	$474K	0.0%	—	—	Put	45780V952
—	ADAMAS PHARMACEUTICALS INC	28,200	$463K	0.0%	$14.46	—	COM	00548A106
—	NOVAVAX INC	2,195	$457K	0.0%	—	—	Call	670002904
—	CHIMERIX INC.	79,900	$443K	0.0%	$5.54	—	COM	16934W106
—	COMBIMATRIX CORP.	857,746	$429K	0.0%	$0.67	—	*W	20009T147
—	AVEXIS ORD SHS	10,000	$412K	0.0%	$41.20	—	COM	05366U100
—	LION BIOTECHNOLOGIES INC	496	$408K	0.0%	—	—	Call	53619R902
—	NEUROMETRIX INC	3,060,947	$400K	0.0%	$0.31	—	*W	641255153
—	THERAPEUTICSMD INC	586	$399K	0.0%	—	—	Put	88338N957
—	FLEXION THERAPEUTICS INC	202	$395K	0.0%	—	—	Put	33938J956
PRQR	PROQR THERAPEUTICS N V	58,910	$393K	0.0%	$7.45	-26.1%	COM	N71542109
—	CASCADIAN THERAPEUTICS INC.	238,899	$392K	0.0%	$0.94	—	COM	14740B101
—	BENITEC BIOPHARMA LTD	274,573	$385K	0.0%	$1.40	—	ADR	82053307
—	MEDICINES CO	100	$377K	0.0%	—	—	Put	584688955
—	ACORDA THERAPEUTICS INC	179	$374K	0.0%	—	—	Call	00484M906
—	BIOPHARMX CORP	654,462	$363K	0.0%	$1.01	—	COM	09072X101
CYH	COMMUNITY HEALTH SYSTEMS INC	31,122	$359K	0.0%	$11.53	0.0%	COM	203668108
—	AMARIN CORPORATION PLC	1,121	$358K	0.0%	—	—	Put	023111956
—	OVASCIENCE INC	50,000	$358K	0.0%	$5.21	—	COM	69014Q101
—	INCYTE CORP	36	$339K	0.0%	—	—	Call	45337C902
—	FIBROGEN INC	164	$339K	0.0%	—	—	Call	31572Q908
—	NEUROMETRIX INC	219,336	$338K	0.0%	$1.76	—	COM	641255500
—	MOMENTA PHARMACEUTICALS INC	275	$321K	0.0%	—	—	Call	60877T900
—	RIGEL PHARMACEUTICALS INC	86,900	$319K	0.0%	$2.23	—	COM	766559603
—	ANAVEX LIFE SCIENCES CORP	858	$311K	0.0%	—	—	Put	032797950
—	JUNO THERAPEUTICS INC	103	$309K	0.0%	—	—	Call	48205A909
—	MEDGENICS INC	533	$297K	0.0%	—	—	Call	58436Q903
—	ANTHERA PHARMACEUTICALS INC	94,201	$297K	0.0%	$3.62	—	COM	03674U201
—	DICERNA PHARMACEUTICALS INC	50,000	$294K	0.0%	$5.88	—	COM	253031108
QRHC	QUEST RESOURCE HOLDING CORP	138,980	$281K	0.0%	$2.35	0.0%	COM	74836W203
—	SYNERGY PHARMACEUTICALS INC.	348,743	$268K	0.0%	$0.77	—	*W	871639118
—	CELLECT BIOTECHNOLOGY LTD	57,348	$264K	0.0%	$4.60	—	ADS	15116C102
OCUL	OCULAR THERAPEUTIX INC	38,100	$262K	0.0%	$6.10	0.0%	COM	67576A100
—	RENNOVA HEALTH INC	3,682,014	$258K	0.0%	$0.07	—	*W	759757123
—	AETERNA ZENTARIS INC	740	$254K	0.0%	—	—	Put	007975952
—	DURECT CORP	1,759	$245K	0.0%	—	—	Call	266605904
—	STEMLINE THERAPEUTICS INC	222	$240K	0.0%	—	—	Call	85858C907
—	FLEXION THERAPEUTICS INC	12,176	$238K	0.0%	$12.31	—	COM	33938J106
—	CAPNIA INC.	245,737	$236K	0.0%	$1.20	—	COM	14066L105
—	THERAPEUTICSMD INC	34,030	$232K	0.0%	$6.82	—	COM	88338N107
—	AETERNA ZENTARIS INC	66,982	$230K	0.0%	$4.48	—	COM	007975402
—	INTRA CELLULAR THERAPIES INC	148	$226K	0.0%	—	—	Put	46116X951
—	INTRA CELLULAR THERAPIES INC	14,800	$226K	0.0%	$27.79	—	COM	46116X101
—	CANCER GENETICS INC	109,048	$191K	0.0%	$2.48	—	COM	13739U104
—	ATHERSYS INC	89,139	$190K	0.0%	$2.17	—	COM	04744L106
—	CELLECTAR BIOSCIENCES INC	228,788	$188K	0.0%	$0.89	—	*W	15117F120
—	NOVAVAX INC	844	$176K	0.0%	—	—	Put	670002954
SRNE	SORRENTO THERAPEUTICS INC	20,986	$162K	0.0%	$11.18	-39.8%	COM	83587F202
—	NATERA INC	145	$161K	0.0%	—	—	Call	632307904
SGMO	SANGAMO BIOSCIENCES INC	32,804	$152K	0.0%	$5.09	0.0%	COM	800677106
—	HISTOGENICS CORP.	47,823	$151K	0.0%	$4.61	—	COM	43358V109
—	NEWLINK GENETICS CORP	100	$150K	0.0%	—	—	Put	651511957
—	AKARI THERAPEUTICS PLC	17,428	$148K	0.0%	$14.89	—	ADR	00972G108
—	EVOKE PHARMA INC.	63,768	$144K	0.0%	$2.26	—	COM	30049G104
—	TONIX PHARMACEUTICALS HOLDING CORP.	203,097	$142K	0.0%	$2.79	—	COM	890260201
—	ALCOBRA LTD	559	$138K	0.0%	—	—	Put	M2239P959
—	INVIVO THERAPEUTICS HOLDINGS CORP	199	$135K	0.0%	—	—	Call	46186M909
—	SORRENTO THERAPEUTICS INC	164	$127K	0.0%	—	—	Call	83587F902
—	RIGEL PHARMACEUTICALS INC	316	$116K	0.0%	—	—	Call	766559903
PVCT	PROVECTUS BIOPHARMACEUTICALS INC	1,077,555	$107K	0.0%	$0.27	-19.2%	COM	74373P108
—	ATHERSYS INC	476	$101K	0.0%	—	—	Put	04744L956
—	INOTEK PHARMACEUTICALS CORP	106	$100K	0.0%	—	—	Call	45780V902
GALT	GALECTIN THERAPEUTICS INC	87,999	$99,000	0.0%	$2.29	-22.4%	COM	363225202
—	GALECTIN THERAPEUTICS INC	825	$93,000	0.0%	—	—	Put	363225952
—	ASTERIAS BIOTHERAPEUTICS INC	200	$85,000	0.0%	—	—	Call	04624N907
—	ZOSANO PHARMA CORP.	103,600	$82,000	0.0%	$9.59	—	COM	98979H103
—	GALENA BIOPHARMA INC	1,624	$57,000	0.0%	—	—	Put	363256958
—	GREAT PANTHER SILVER LTD	40,450	$55,000	0.0%	$1.36	—	COM	39115V101
—	INSPIREMD INC	679,224	$54,000	0.0%	$0.08	—	COM	45779A507
—	EDAP TMS S A	182	$53,000	0.0%	—	—	Put	268311957
—	VIKING THERAPEUTICS INC	117,008	$53,000	0.0%	$0.29	—	*W	92686J114
—	ADAMIS PHARMACEUTICALS CORP	148	$51,000	0.0%	—	—	Put	00547W958
—	GALENA BIOPHARMA INC	141,000	$49,000	0.0%	$0.44	—	COM	363256108
—	ALCOBRA LTD	17,058	$42,000	0.0%	$5.87	—	SHS	M2239P109
—	TENAX THERAPEUTICS INC	169	$39,000	0.0%	—	—	Put	88032L950
—	INFINITY PHARMACEUTICALS INC	167	$26,000	0.0%	—	—	Call	45665G903
—	BENITEC BIOPHARMA LTD	98,146	$17,000	0.0%	$0.36	—	*W	082053117
—	EYEGATE PHARMACEUTICALS INC	46,968	$16,000	0.0%	$1.02	—	*W	30233M115
—	ZAFGEN INC	2,149	$15,000	0.0%	—	—	Call	98885E903