RA CAPITAL MANAGEMENT, L.P. Diversified Active

CIK: 0001346824 · Show all filings

Period: Q4 2016 (← Previous) (Next →)

Filing Date: Feb 16, 2017

Total Value ($000): $705,844

Holdings (27)

WVE WAVE LIFE SCIENCES LTD 26.3%

Value ($000) $185,368 Shares 7,088,651 Est. Cost $15.68 Unrealized +107.4%

ASND ASCENDIS PHARMA A S 15.5%

Value ($000) $109,498 Shares 5,409,990 Est. Cost $17.65 Unrealized —

— AVEXIS INC 12.8%

Value ($000) $90,248 Shares 1,890,796 Est. Cost $31.86 Unrealized —

— ACHILLION PHARMACEUTICALS INC 8.0%

Value ($000) $56,305 Shares 13,633,220 Est. Cost $6.18 Unrealized —

— AQUINOX PHARMACEUTICALS INC 5.1%

Value ($000) $36,190 Shares 2,191,977 Est. Cost $13.67 Unrealized —

— ZOGENIX INC 4.2%

Value ($000) $29,783 Shares 2,451,237 Est. Cost $13.32 Unrealized —

ARDX ARDELYX INC 3.9%

Value ($000) $27,481 Shares 1,935,305 Est. Cost $10.51 Unrealized +35.0%

— RA PHARMACEUTICALS INC 2.9%

Value ($000) $20,534 Shares 1,351,808 Est. Cost $15.19 Unrealized —

— FOAMIX PHARMACEUTICALS LTD 2.9%

Value ($000) $20,204 Shares 1,820,138 Est. Cost $9.26 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 2.7%

Value ($000) $18,925 Shares 2,989,795 Est. Cost $9.58 Unrealized -45.7%

— MYOVANT SCIENCES LTD 2.6%

Value ($000) $18,660 Shares 1,500,000 Est. Cost $12.44 Unrealized —

PTGX PROTAGONIST THERAPEUTICS INC 2.1%

Value ($000) $14,634 Shares 692,563 Est. Cost $13.67 Unrealized +63.1%

— AIMMUNE THERAPEUTICS INC 2.0%

Value ($000) $13,858 Shares 677,663 Est. Cost $20.75 Unrealized —

— AUDENTES THERAPEUTICS INC 1.4%

Value ($000) $9,727 Shares 532,426 Est. Cost $17.81 Unrealized —

ONC BEIGENE LTD 1.0%

Value ($000) $7,286 Shares 240,000 Est. Cost $29.62 Unrealized —

— DICERNA PHARMACEUTICALS INC 1.0%

Value ($000) $6,994 Shares 2,428,571 Est. Cost $28.25 Unrealized —

— ABEONA THERAPEUTICS INC 0.8%

Value ($000) $5,543 Shares 1,142,857 Est. Cost $4.85 Unrealized —

— STRONGBRIDGE BIOPHARMA PLC 0.8%

Value ($000) $5,470 Shares 2,279,099 Est. Cost $7.60 Unrealized —

TGTX TG THERAPEUTICS INC 0.7%

Value ($000) $4,670 Shares 1,004,314 Est. Cost $10.06 Unrealized -41.7%

— TENAX THERAPEUTICS INC 0.7%

Value ($000) $4,660 Shares 2,389,700 Est. Cost $3.92 Unrealized —

KALV KALVISTA PHARMACEUTICALS INC 0.6%

Value ($000) $4,179 Shares 591,070 Est. Cost $7.37 Unrealized 0.0%

— EIGER BIOPHARMACEUTICALS INC 0.6%

Value ($000) $4,126 Shares 354,200 Est. Cost $16.17 Unrealized —

— DIMENSION THERAPEUTICS INC 0.6%

Value ($000) $4,038 Shares 928,199 Est. Cost $10.25 Unrealized —

— IDERA PHARMACEUTICALS INC 0.5%

Value ($000) $3,375 Shares 2,250,000 Est. Cost $1.50 Unrealized —

— MEDICINES CO 0.4%

Value ($000) $2,712 Shares 79,899 Est. Cost $33.94 Unrealized —

— AKARI THERAPEUTICS PLC 0.1%

Value ($000) $714 Shares 101,439 Est. Cost $24.00 Unrealized —

— ARCA BIOPHARMA INC 0.1%

Value ($000) $662 Shares 232,245 Est. Cost $4.96 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	7,088,651	$185,368	26.3%	$15.68	+107.4%	—	Y95308105
ASND	ASCENDIS PHARMA A S	5,409,990	$109,498	15.5%	$17.65	—	—	04351P101
—	AVEXIS INC	1,890,796	$90,248	12.8%	$31.86	—	—	05366U100
—	ACHILLION PHARMACEUTICALS INC	13,633,220	$56,305	8.0%	$6.18	—	—	00448Q201
—	AQUINOX PHARMACEUTICALS INC	2,191,977	$36,190	5.1%	$13.67	—	—	03842B101
—	ZOGENIX INC	2,451,237	$29,783	4.2%	$13.32	—	—	98978L204
ARDX	ARDELYX INC	1,935,305	$27,481	3.9%	$10.51	+35.0%	—	039697107
—	RA PHARMACEUTICALS INC	1,351,808	$20,534	2.9%	$15.19	—	—	74933V108
—	FOAMIX PHARMACEUTICALS LTD	1,820,138	$20,204	2.9%	$9.26	—	—	M46135105
BCRX	BIOCRYST PHARMACEUTICALS	2,989,795	$18,925	2.7%	$9.58	-45.7%	—	09058V103
—	MYOVANT SCIENCES LTD	1,500,000	$18,660	2.6%	$12.44	—	—	G637AM102
PTGX	PROTAGONIST THERAPEUTICS INC	692,563	$14,634	2.1%	$13.67	+63.1%	—	74366E102
—	AIMMUNE THERAPEUTICS INC	677,663	$13,858	2.0%	$20.75	—	—	00900T107
—	AUDENTES THERAPEUTICS INC	532,426	$9,727	1.4%	$17.81	—	—	05070R104
ONC	BEIGENE LTD	240,000	$7,286	1.0%	$29.62	—	—	07725L102
—	DICERNA PHARMACEUTICALS INC	2,428,571	$6,994	1.0%	$28.25	—	—	253031108
—	ABEONA THERAPEUTICS INC	1,142,857	$5,543	0.8%	$4.85	—	—	00289Y107
—	STRONGBRIDGE BIOPHARMA PLC	2,279,099	$5,470	0.8%	$7.60	—	—	G85347105
TGTX	TG THERAPEUTICS INC	1,004,314	$4,670	0.7%	$10.06	-41.7%	—	88322Q108
—	TENAX THERAPEUTICS INC	2,389,700	$4,660	0.7%	$3.92	—	—	88032L100
KALV	KALVISTA PHARMACEUTICALS INC	591,070	$4,179	0.6%	$7.37	0.0%	—	483497103
—	EIGER BIOPHARMACEUTICALS INC	354,200	$4,126	0.6%	$16.17	—	—	28249U105
—	DIMENSION THERAPEUTICS INC	928,199	$4,038	0.6%	$10.25	—	—	25433V105
—	IDERA PHARMACEUTICALS INC	2,250,000	$3,375	0.5%	$1.50	—	—	45168K306
—	MEDICINES CO	79,899	$2,712	0.4%	$33.94	—	—	584688105
—	AKARI THERAPEUTICS PLC	101,439	$714	0.1%	$24.00	—	—	00972G108
—	ARCA BIOPHARMA INC	232,245	$662	0.1%	$4.96	—	—	00211Y407