RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q4 2016 (← Previous) (Next →)

Filing Date: Feb 16, 2017

Total Value: $706M (100.0% shares, 0.0% debt)

Holdings (27)

WVE WAVE LIFE SCIENCES LTD 26.3%

Value $185M Shares 7,088,651 Share Price $26.15 * Est. Cost/Share $15.68 Unrealized @ Report Date +107.4%

ASND ASCENDIS PHARMA A S 15.5%

Value $109M Shares 5,409,990 Share Price $20.24 Est. Cost/Share $17.65 Unrealized @ Report Date —

— AVEXIS INC 12.8%

Value $90.25M Shares 1,890,796 Share Price $47.73 Est. Cost/Share $31.86 Unrealized @ Report Date —

— ACHILLION PHARMACEUTICALS INC 8.0%

Value $56.3M Shares 13,633,220 Share Price $4.13 Est. Cost/Share $6.18 Unrealized @ Report Date —

— AQUINOX PHARMACEUTICALS INC 5.1%

Value $36.19M Shares 2,191,977 Share Price $16.51 Est. Cost/Share $13.67 Unrealized @ Report Date —

— ZOGENIX INC 4.2%

Value $29.78M Shares 2,451,237 Share Price $12.15 Est. Cost/Share $13.32 Unrealized @ Report Date —

ARDX ARDELYX INC 3.9%

Value $27.48M Shares 1,935,305 Share Price $14.20 Est. Cost/Share $10.51 Unrealized @ Report Date +35.0%

— RA PHARMACEUTICALS INC 2.9%

Value $20.53M Shares 1,351,808 Share Price $15.19 Est. Cost/Share $15.19 Unrealized @ Report Date —

— FOAMIX PHARMACEUTICALS LTD 2.9%

Value $20.2M Shares 1,820,138 Share Price $11.10 Est. Cost/Share $9.26 Unrealized @ Report Date —

BCRX BIOCRYST PHARMACEUTICALS 2.7%

Value $18.93M Shares 2,989,795 Share Price $6.33 * Est. Cost/Share $9.58 Unrealized @ Report Date -45.7%

— MYOVANT SCIENCES LTD 2.6%

Value $18.66M Shares 1,500,000 Share Price $12.44 Est. Cost/Share $12.44 Unrealized @ Report Date —

PTGX PROTAGONIST THERAPEUTICS INC 2.1%

Value $14.63M Shares 692,563 Share Price $21.13 * Est. Cost/Share $13.67 Unrealized @ Report Date +63.1%

— AIMMUNE THERAPEUTICS INC 2.0%

Value $13.86M Shares 677,663 Share Price $20.45 Est. Cost/Share $20.75 Unrealized @ Report Date —

— AUDENTES THERAPEUTICS INC 1.4%

Value $9.727M Shares 532,426 Share Price $18.27 Est. Cost/Share $17.81 Unrealized @ Report Date —

ONC BEIGENE LTD 1.0%

Value $7.286M Shares 240,000 Share Price $30.36 Est. Cost/Share $29.62 Unrealized @ Report Date —

— DICERNA PHARMACEUTICALS INC 1.0%

Value $6.994M Shares 2,428,571 Share Price $2.88 Est. Cost/Share $28.25 Unrealized @ Report Date —

— ABEONA THERAPEUTICS INC 0.8%

Value $5.543M Shares 1,142,857 Share Price $4.85 Est. Cost/Share $4.85 Unrealized @ Report Date —

— STRONGBRIDGE BIOPHARMA PLC 0.8%

Value $5.47M Shares 2,279,099 Share Price $2.40 Est. Cost/Share $7.60 Unrealized @ Report Date —

TGTX TG THERAPEUTICS INC 0.7%

Value $4.67M Shares 1,004,314 Share Price $4.65 * Est. Cost/Share $10.06 Unrealized @ Report Date -41.7%

— TENAX THERAPEUTICS INC 0.7%

Value $4.66M Shares 2,389,700 Share Price $1.95 Est. Cost/Share $3.92 Unrealized @ Report Date —

KALV KALVISTA PHARMACEUTICALS INC 0.6%

Value $4.179M Shares 591,070 Share Price $7.07 * Est. Cost/Share $7.37 Unrealized @ Report Date 0.0%

— EIGER BIOPHARMACEUTICALS INC 0.6%

Value $4.126M Shares 354,200 Share Price $11.65 Est. Cost/Share $16.17 Unrealized @ Report Date —

— DIMENSION THERAPEUTICS INC 0.6%

Value $4.038M Shares 928,199 Share Price $4.35 Est. Cost/Share $10.25 Unrealized @ Report Date —

— IDERA PHARMACEUTICALS INC 0.5%

Value $3.375M Shares 2,250,000 Share Price $1.50 Est. Cost/Share $1.50 Unrealized @ Report Date —

— MEDICINES CO 0.4%

Value $2.712M Shares 79,899 Share Price $33.94 Est. Cost/Share $33.94 Unrealized @ Report Date —

— AKARI THERAPEUTICS PLC 0.1%

Value $714K Shares 101,439 Share Price $7.04 Est. Cost/Share $24.00 Unrealized @ Report Date —

— ARCA BIOPHARMA INC 0.1%

Value $662K Shares 232,245 Share Price $2.85 Est. Cost/Share $4.96 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	7,088,651	$185M	26.3%	$26.15 *	$15.68	+107.4%	SHS	Y95308105
ASND	ASCENDIS PHARMA A S	5,409,990	$109M	15.5%	$20.24	$17.65	—	SPONSORED ADR	04351P101
—	AVEXIS INC	1,890,796	$90.25M	12.8%	$47.73	$31.86	—	COM	05366U100
—	ACHILLION PHARMACEUTICALS INC	13,633,220	$56.3M	8.0%	$4.13	$6.18	—	COM	00448Q201
—	AQUINOX PHARMACEUTICALS INC	2,191,977	$36.19M	5.1%	$16.51	$13.67	—	COM	03842B101
—	ZOGENIX INC	2,451,237	$29.78M	4.2%	$12.15	$13.32	—	COM NEW	98978L204
ARDX	ARDELYX INC	1,935,305	$27.48M	3.9%	$14.20	$10.51	+35.0%	COM	039697107
—	RA PHARMACEUTICALS INC	1,351,808	$20.53M	2.9%	$15.19	$15.19	—	COM	74933V108
—	FOAMIX PHARMACEUTICALS LTD	1,820,138	$20.2M	2.9%	$11.10	$9.26	—	SHS	M46135105
BCRX	BIOCRYST PHARMACEUTICALS	2,989,795	$18.93M	2.7%	$6.33 *	$9.58	-45.7%	COM	09058V103
—	MYOVANT SCIENCES LTD	1,500,000	$18.66M	2.6%	$12.44	$12.44	—	COM	G637AM102
PTGX	PROTAGONIST THERAPEUTICS INC	692,563	$14.63M	2.1%	$21.13 *	$13.67	+63.1%	COM	74366E102
—	AIMMUNE THERAPEUTICS INC	677,663	$13.86M	2.0%	$20.45	$20.75	—	COM	00900T107
—	AUDENTES THERAPEUTICS INC	532,426	$9.727M	1.4%	$18.27	$17.81	—	COM	05070R104
ONC	BEIGENE LTD	240,000	$7.286M	1.0%	$30.36	$29.62	—	SPONSORED ADR	07725L102
—	DICERNA PHARMACEUTICALS INC	2,428,571	$6.994M	1.0%	$2.88	$28.25	—	COM	253031108
—	ABEONA THERAPEUTICS INC	1,142,857	$5.543M	0.8%	$4.85	$4.85	—	COM	00289Y107
—	STRONGBRIDGE BIOPHARMA PLC	2,279,099	$5.47M	0.8%	$2.40	$7.60	—	SHS USD	G85347105
TGTX	TG THERAPEUTICS INC	1,004,314	$4.67M	0.7%	$4.65 *	$10.06	-41.7%	COM	88322Q108
—	TENAX THERAPEUTICS INC	2,389,700	$4.66M	0.7%	$1.95	$3.92	—	COM	88032L100
KALV	KALVISTA PHARMACEUTICALS INC	591,070	$4.179M	0.6%	$7.07 *	$7.37	0.0%	COM	483497103
—	EIGER BIOPHARMACEUTICALS INC	354,200	$4.126M	0.6%	$11.65	$16.17	—	COM	28249U105
—	DIMENSION THERAPEUTICS INC	928,199	$4.038M	0.6%	$4.35	$10.25	—	COM	25433V105
—	IDERA PHARMACEUTICALS INC	2,250,000	$3.375M	0.5%	$1.50	$1.50	—	COM NEW	45168K306
—	MEDICINES CO	79,899	$2.712M	0.4%	$33.94	$33.94	—	COM	584688105
—	AKARI THERAPEUTICS PLC	101,439	$714K	0.1%	$7.04	$24.00	—	SPONSORED ADR	00972G108
—	ARCA BIOPHARMA INC	232,245	$662K	0.1%	$2.85	$4.96	—	COM PAR$.001	00211Y407