Rock Springs Capital Management LP Diversified Active

CIK: 0001595725 · Show all filings

Period: Q1 2023 (← Previous) (Next →)

Filing Date: May 15, 2023

Total Value ($000): $4,191,252 (99.8% shares, 0.2% debt)

Holdings (121)

HUM HUMANA INC 4.9%
Value ($000) $207,049 Shares 426,500 Est. Cost $361.45 Unrealized +32.4%
AGL AGILON HEALTH INC 4.5%
Value ($000) $187,209 Shares 7,882,500 Est. Cost $33.92 Unrealized -34.0%
PODD INSULET CORP 4.1%
Value ($000) $171,202 Shares 536,750 Est. Cost $180.60 Unrealized +64.1%
IMCR IMMUNOCORE HLDGS PLC 3.5%
Value ($000) $148,402 Shares 3,001,662 Est. Cost $42.88 Unrealized —
ARGX ARGENX SE 3.1%
Value ($000) $130,403 Shares 350,000 Est. Cost $153.41 Unrealized —
UNH UNITEDHEALTH GROUP INC 3.0%
Value ($000) $127,599 Shares 270,000 Est. Cost $219.29 Unrealized +108.5%
EVH EVOLENT HEALTH INC 2.9%
Value ($000) $123,424 Shares 3,803,500 Est. Cost $24.94 Unrealized +26.8%
NBIX NEUROCRINE BIOSCIENCES INC 2.9%
Value ($000) $122,486 Shares 1,210,100 Est. Cost $77.07 Unrealized +35.0%
PEN PENUMBRA INC 2.9%
Value ($000) $120,812 Shares 433,500 Est. Cost $138.03 Unrealized +84.9%
— PROMETHEUS BIOSCIENCES INC 2.6%
Value ($000) $110,706 Shares 1,031,550 Est. Cost $53.18 Unrealized —
IDXX IDEXX LABS INC 2.5%
Value ($000) $103,767 Shares 207,500 Est. Cost $335.38 Unrealized +42.7%
— BLUEPRINT MEDICINES CORP 2.2%
Value ($000) $91,467 Shares 2,033,048 Est. Cost $63.30 Unrealized —
— KARUNA THERAPEUTICS INC 2.1%
Value ($000) $89,644 Shares 493,527 Est. Cost $92.95 Unrealized —
MDGL MADRIGAL PHARMACEUTICALS INC 2.0%
Value ($000) $84,336 Shares 348,121 Est. Cost $51.77 Unrealized +426.3%
ALGN ALIGN TECHNOLOGY INC 2.0%
Value ($000) $82,650 Shares 247,350 Est. Cost $313.91 Unrealized -6.0%
— SEAGEN INC 1.9%
Value ($000) $81,028 Shares 400,200 Est. Cost $158.76 Unrealized —
— HORIZON THERAPEUTICS PUB L 1.9%
Value ($000) $80,775 Shares 740,100 Est. Cost $83.28 Unrealized —
ISRG INTUITIVE SURGICAL INC 1.8%
Value ($000) $76,258 Shares 298,500 Est. Cost $264.69 Unrealized -6.9%
WST WEST PHARMACEUTICAL SVSC INC 1.7%
Value ($000) $69,987 Shares 202,000 Est. Cost $294.97 Unrealized -1.7%
ALNY ALNYLAM PHARMACEUTICALS INC 1.6%
Value ($000) $69,110 Shares 345,000 Est. Cost $99.88 Unrealized +110.4%
EXAS EXACT SCIENCES CORP 1.5%
Value ($000) $63,843 Shares 941,500 Est. Cost $51.74 Unrealized +24.2%
ACHC ACADIA HEALTHCARE COMPANY IN 1.5%
Value ($000) $62,198 Shares 860,868 Est. Cost $50.01 Unrealized +55.9%
— CEREVEL THERAPEUTICS HLDNG I 1.5%
Value ($000) $61,314 Shares 2,513,916 Est. Cost $24.09 Unrealized —
AGIO AGIOS PHARMACEUTICALS INC 1.5%
Value ($000) $61,137 Shares 2,661,605 Est. Cost $40.40 Unrealized -34.2%
SRPT SAREPTA THERAPEUTICS INC 1.5%
Value ($000) $60,990 Shares 442,500 Est. Cost $62.74 Unrealized +106.8%
DXCM DEXCOM INC 1.4%
Value ($000) $56,986 Shares 490,500 Est. Cost $94.31 Unrealized +18.7%
— AKERO THERAPEUTICS INC 1.3%
Value ($000) $55,640 Shares 1,454,254 Est. Cost $29.34 Unrealized —
RARE ULTRAGENYX PHARMACEUTICAL IN 1.3%
Value ($000) $53,590 Shares 1,336,401 Est. Cost $66.17 Unrealized -35.1%
EW EDWARDS LIFESCIENCES CORP 1.3%
Value ($000) $53,435 Shares 645,900 Est. Cost $62.58 Unrealized +25.6%
ASND ASCENDIS PHARMA A/S 1.1%
Value ($000) $45,622 Shares 425,500 Est. Cost $85.24 Unrealized —
FRPT FRESHPET INC 1.0%
Value ($000) $43,851 Shares 662,500 Est. Cost $60.72 Unrealized +1.1%
MIRM MIRUM PHARMACEUTICALS INC 1.0%
Value ($000) $43,134 Shares 1,795,733 Est. Cost $14.23 Unrealized +60.1%
AMLX AMYLYX PHARMACEUTICALS INC 1.0%
Value ($000) $42,626 Shares 1,452,816 Est. Cost $31.75 Unrealized +9.4%
XENE XENON PHARMACEUTICALS INC 1.0%
Value ($000) $42,161 Shares 1,178,002 Est. Cost $22.63 Unrealized +63.2%
PCRX PACIRA BIOSCIENCES INC 1.0%
Value ($000) $42,140 Shares 1,032,600 Est. Cost $48.65 Unrealized -18.2%
PHR PHREESIA INC 1.0%
Value ($000) $42,058 Shares 1,302,500 Est. Cost $28.73 Unrealized +22.5%
BMEA BIOMEA FUSION INC 1.0%
Value ($000) $40,227 Shares 1,297,213 Est. Cost $15.37 Unrealized -19.2%
— MIRATI THERAPEUTICS INC 0.9%
Value ($000) $39,606 Shares 1,065,261 Est. Cost $70.86 Unrealized —
— NEVRO CORP 0.9%
Value ($000) $38,966 Shares 1,077,900 Est. Cost $81.31 Unrealized —
IRTC IRHYTHM TECHNOLOGIES INC 0.9%
Value ($000) $38,381 Shares 309,450 Est. Cost $65.15 Unrealized +66.5%
— OLINK HLDG AB 0.9%
Value ($000) $37,175 Shares 1,650,000 Est. Cost $22.21 Unrealized —
— ACCOLADE INC 0.9%
Value ($000) $36,597 Shares 2,545,000 Est. Cost $22.71 Unrealized —
PRTA PROTHENA CORP PLC 0.9%
Value ($000) $36,520 Shares 753,462 Est. Cost $17.26 Unrealized +206.0%
KYMR KYMERA THERAPEUTICS INC 0.9%
Value ($000) $36,397 Shares 1,228,379 Est. Cost $31.64 Unrealized +1.9%
ZLAB ZAI LAB LTD 0.8%
Value ($000) $35,246 Shares 1,059,700 Est. Cost $61.65 Unrealized —
ACRS ACLARIS THERAPEUTICS INC 0.8%
Value ($000) $32,051 Shares 3,961,849 Est. Cost $10.84 Unrealized +17.1%
— ABCAM PLC 0.7%
Value ($000) $30,184 Shares 2,242,500 Est. Cost $18.75 Unrealized —
TVTX TRAVERE THERAPEUTICS INC 0.7%
Value ($000) $28,712 Shares 1,276,650 Est. Cost $23.75 Unrealized -10.5%
RYTM RHYTHM PHARMACEUTICALS INC 0.7%
Value ($000) $28,493 Shares 1,597,123 Est. Cost $15.80 Unrealized +59.0%
XLV SELECT SECTOR SPDR TR 0.6%
Value ($000) $25,892 Shares 200,000 Est. Cost $128.24 Unrealized —
BMRN BIOMARIN PHARMACEUTICAL INC 0.6%
Value ($000) $25,720 Shares 264,500 Est. Cost $85.70 Unrealized +21.0%
— SHOCKWAVE MED INC 0.6%
Value ($000) $24,957 Shares 115,100 Est. Cost $79.81 Unrealized —
LEGN LEGEND BIOTECH CORP 0.5%
Value ($000) $22,098 Shares 458,265 Est. Cost $40.20 Unrealized —
LFST LIFESTANCE HEALTH GROUP INC 0.5%
Value ($000) $21,547 Shares 2,900,000 Est. Cost $17.93 Unrealized -69.1%
CNMD CONMED CORP 0.5%
Value ($000) $21,291 Shares 205,000 Est. Cost $114.00 Unrealized -17.5%
BCRX BIOCRYST PHARMACEUTICALS INC 0.5%
Value ($000) $19,466 Shares 2,334,085 Est. Cost $10.62 Unrealized -9.4%
— AMRYT PHARMA PLC 0.5%
Value ($000) $19,328 Shares 1,325,625 Est. Cost $12.05 Unrealized —
AZTA AZENTA INC 0.5%
Value ($000) $19,240 Shares 431,200 Est. Cost $63.06 Unrealized -21.5%
— INOZYME PHARMA INC 0.4%
Value ($000) $18,421 Shares 3,214,900 Est. Cost $9.93 Unrealized —
MLYS MINERALYS THERAPEUTICS INC 0.4%
Value ($000) $18,283 Shares 1,167,492 Est. Cost $16.83 Unrealized 0.0%
CMPX COMPASS THERAPEUTICS INC 0.4%
Value ($000) $18,030 Shares 5,513,788 Est. Cost $3.31 Unrealized +18.6%
— DYNAVAX TECHNOLOGIES CORP 0.4%
Value ($000) $17,793 Shares 1,813,758 Est. Cost $7.97 Unrealized —
IMTX IMMATICS N.V 0.4%
Value ($000) $17,346 Shares 2,513,923 Est. Cost $9.14 Unrealized -10.5%
— MERSANA THERAPEUTICS INC 0.4%
Value ($000) $16,867 Shares 4,103,803 Est. Cost $13.04 Unrealized —
CYTK CYTOKINETICS INC 0.4%
Value ($000) $15,751 Shares 447,600 Est. Cost $41.02 Unrealized -0.6%
COLL COLLEGIUM PHARMACEUTICAL INC 0.4%
Value ($000) $15,594 Shares 650,000 Est. Cost $15.97 Unrealized +66.0%
RVMD REVOLUTION MEDICINES INC 0.4%
Value ($000) $15,221 Shares 702,712 Est. Cost $24.62 Unrealized 0.0%
CLDX CELLDEX THERAPEUTICS INC NEW 0.4%
Value ($000) $15,166 Shares 421,504 Est. Cost $30.05 Unrealized +43.6%
WRBY WARBY PARKER INC 0.3%
Value ($000) $13,767 Shares 1,300,000 Est. Cost $39.64 Unrealized -65.4%
PLRX PLIANT THERAPEUTICS INC 0.3%
Value ($000) $13,066 Shares 491,221 Est. Cost $28.47 Unrealized 0.0%
ANAB ANAPTYSBIO INC 0.3%
Value ($000) $12,547 Shares 576,600 Est. Cost $28.23 Unrealized -13.9%
FOLD AMICUS THERAPEUTICS INC 0.3%
Value ($000) $11,798 Shares 1,063,806 Est. Cost $11.48 Unrealized +7.4%
— CHINOOK THERAPEUTICS INC 0.3%
Value ($000) $11,749 Shares 507,512 Est. Cost $15.86 Unrealized —
EDAP EDAP TMS S A 0.3%
Value ($000) $11,402 Shares 1,030,000 Est. Cost $7.54 Unrealized —
RLAY RELAY THERAPEUTICS INC 0.3%
Value ($000) $11,100 Shares 673,966 Est. Cost $33.24 Unrealized -46.1%
HCAT HEALTH CATALYST INC 0.3%
Value ($000) $10,852 Shares 929,900 Est. Cost $33.08 Unrealized -61.5%
AURA AURA BIOSCIENCES INC 0.2%
Value ($000) $9,463 Shares 1,019,757 Est. Cost $17.87 Unrealized -41.9%
BHVN BIOHAVEN LTD 0.2%
Value ($000) $9,366 Shares 685,623 Est. Cost $12.49 Unrealized +27.5%
— VERVE THERAPEUTICS INC 0.2%
Value ($000) $8,058 Shares 558,837 Est. Cost $57.71 Unrealized —
MGNX MACROGENICS INC 0.2%
Value ($000) $8,053 Shares 1,123,096 Est. Cost $17.45 Unrealized -65.5%
NVCR NOVOCURE LTD 0.2%
Value ($000) $7,518 Shares 125,000 Est. Cost $37.58 Unrealized +112.6%
LUNG PULMONX CORP 0.2%
Value ($000) $7,294 Shares 652,400 Est. Cost $45.31 Unrealized -78.2%
— RENEO PHARMACEUTICALS INC 0.2%
Value ($000) $6,836 Shares 1,143,185 Est. Cost $9.31 Unrealized —
IRON DISC MEDICINE INC 0.2%
Value ($000) $6,642 Shares 313,468 Est. Cost $49.79 Unrealized -55.3%
— SPRUCE BIOSCIENCES INC 0.1%
Value ($000) $6,029 Shares 2,728,125 Est. Cost $15.23 Unrealized —
AUPH AURINIA PHARMACEUTICALS INC 0.1%
Value ($000) $5,256 Shares 479,540 Est. Cost $13.26 Unrealized -33.6%
— ICOSAVAX INC 0.1%
Value ($000) $5,014 Shares 864,510 Est. Cost $26.02 Unrealized —
GH GUARDANT HEALTH INC 0.1%
Value ($000) $4,688 Shares 200,000 Est. Cost $42.73 Unrealized -33.2%
— KINNATE BIOPHARMA INC 0.1%
Value ($000) $4,669 Shares 746,973 Est. Cost $24.53 Unrealized —
— VIGIL NEUROSCIENCE INC 0.1%
Value ($000) $4,620 Shares 471,958 Est. Cost $7.03 Unrealized —
XLO XILIO THERAPEUTICS INC 0.1%
Value ($000) $4,567 Shares 1,440,759 Est. Cost $14.70 Unrealized -78.7%
MREO MEREO BIOPHARMA GROUP PLC 0.1%
Value ($000) $4,415 Shares 6,244,897 Est. Cost $2.88 Unrealized —
— PARATEK PHARMACEUTICALS INC 0.1%
Value ($000) $4,404 Shares 1,734,037 Est. Cost $6.08 Unrealized —
— INVITAE CORP 0.1%
Value ($000) $4,376 Shares 3,241,425 Est. Cost $19.23 Unrealized —
— THESEUS PHARMACEUTICALS INC 0.1%
Value ($000) $3,883 Shares 437,329 Est. Cost $12.68 Unrealized —
NVAX NOVAVAX INC 0.1%
Value ($000) $3,710 Shares 535,400 Est. Cost $43.41 Unrealized -78.8%
FATE FATE THERAPEUTICS INC 0.1%
Value ($000) $3,490 Shares 612,215 Est. Cost $21.03 Unrealized -71.3%
BEAM BEAM THERAPEUTICS INC 0.1%
Value ($000) $3,412 Shares 111,430 Est. Cost $39.75 Unrealized -0.7%
— TRAVERE THERAPEUTICS INC 0.1%
Value ($000) $3,126 Shares 3,250,000 Est. Cost $0.79 Unrealized —
ADAPY ADAPTIMMUNE THERAPEUTICS PLC 0.1%
Value ($000) $3,039 Shares 2,787,845 Est. Cost $7.10 Unrealized —
DSGN DESIGN THERAPEUTICS INC 0.1%
Value ($000) $2,656 Shares 460,391 Est. Cost $26.33 Unrealized -71.6%
— GOSSAMER BIO INC 0.1%
Value ($000) $2,641 Shares 9,573,000 Est. Cost $1.01 Unrealized —
— 89BIO INC 0.1%
Value ($000) $2,505 Shares 164,500 Est. Cost — Unrealized —
FULC FULCRUM THERAPEUTICS INC 0.0%
Value ($000) $2,074 Shares 727,673 Est. Cost $14.24 Unrealized -37.1%
— TEMPEST THERAPEUTICS INC 0.0%
Value ($000) $1,911 Shares 823,654 Est. Cost $7.50 Unrealized —
— GAMIDA CELL LTD 0.0%
Value ($000) $1,899 Shares 2,344,649 Est. Cost $3.36 Unrealized —
— LEAP THERAPEUTICS INC 0.0%
Value ($000) $1,583 Shares 4,655,186 Est. Cost $3.15 Unrealized —
— ESSA PHARMA INC 0.0%
Value ($000) $1,559 Shares 524,944 Est. Cost $28.44 Unrealized —
NKTX NKARTA INC 0.0%
Value ($000) $1,397 Shares 393,389 Est. Cost $26.66 Unrealized -82.2%
GOSS GOSSAMER BIO INC 0.0%
Value ($000) $1,386 Shares 1,100,274 Est. Cost $5.50 Unrealized -65.2%
— NEUROCRINE BIOSCIENCES INC 0.0%
Value ($000) $1,352 Shares 1,000,000 Est. Cost $1.45 Unrealized —
— AEGLEA BIOTHERAPEUTICS INC 0.0%
Value ($000) $990 Shares 3,413,906 Est. Cost $4.00 Unrealized —
SPRO SPERO THERAPEUTICS INC 0.0%
Value ($000) $971 Shares 669,533 Est. Cost $11.75 Unrealized -85.7%
ALT ALTIMMUNE INC 0.0%
Value ($000) $942 Shares 223,255 Est. Cost $14.76 Unrealized -19.5%
— VINCERX PHARMA INC 0.0%
Value ($000) $927 Shares 891,719 Est. Cost $12.19 Unrealized —
CGEN COMPUGEN LTD 0.0%
Value ($000) $906 Shares 1,289,990 Est. Cost $6.12 Unrealized -86.6%
— APPLIED THERAPEUTICS INC 0.0%
Value ($000) $633 Shares 780,791 Est. Cost $24.45 Unrealized —
— NEVRO CORP 0.0%
Value ($000) $470 Shares 500,000 Est. Cost $1.37 Unrealized —
— ATRECA INC 0.0%
Value ($000) $413 Shares 362,530 Est. Cost $13.90 Unrealized —
TLPH ACELRX PHARMACEUTICALS INC 0.0%
Value ($000) $208 Shares 316,460 Est. Cost $2.81 Unrealized -43.8%
— NUVATION BIO INC 0.0%
Value ($000) $16 Shares 134,028 Est. Cost $2.67 Unrealized —