Sio Capital Management, LLC Hedge Fund

Location: New York, NY

CIK: 0001482416 · Show all filings

Period: Q1 2021 (← Previous) (Next →)

Filing Date: May 14, 2021

Total Value: $493M (100.0% shares, 0.0% debt)

Holdings (89)

— CURIS INC 10.1%
Value $49.6M Shares 4,381,668 Share Price $11.32 Est. Cost/Share $1.20 Unrealized @ Report Date —
CI CIGNA CORP 5.2%
Value $25.86M Shares 106,965 Share Price $241.74 * Est. Cost/Share $179.06 Unrealized @ Report Date +14.0%
CAH CARDINAL HEALTH INC 3.4%
Value $16.7M Shares 274,917 Share Price $60.75 * Est. Cost/Share $46.44 Unrealized @ Report Date +5.4%
GLD SPDR GOLD SHARES 3.1%
Value $15.52M Shares 97,009 Share Price $159.96 Est. Cost/Share $158.19 Unrealized @ Report Date —
— SOLITON INC 2.9%
Value $14.49M Shares 824,803 Share Price $17.57 Est. Cost/Share $7.78 Unrealized @ Report Date —
CNC CENTENE CORP 2.8%
Value $13.9M Shares 217,500 Share Price $63.91 * Est. Cost/Share $61.92 Unrealized @ Report Date 0.0%
HCA HCA HEALTHCARE INC 2.8%
Value $13.78M Shares 73,173 Share Price $188.33 * Est. Cost/Share $111.08 Unrealized @ Report Date +52.1%
— SPRUCE BIOSCIENCES INC 2.7%
Value $13.49M Shares 812,884 Share Price $16.60 Est. Cost/Share $22.64 Unrealized @ Report Date —
CHRS COHERUS BIOSCIENCES INC 2.5%
Value $12.39M Shares 847,862 Share Price $14.61 * Est. Cost/Share $18.76 Unrealized @ Report Date -9.5%
— HILL-ROM HOLDINGS INC 2.4%
Value $11.89M Shares 107,647 Share Price $110.48 Est. Cost/Share $95.34 Unrealized @ Report Date —
— CEL-SCI CORP 2.1%
Value $10.58M Shares 695,700 Share Price $15.21 Est. Cost/Share — Unrealized @ Report Date —
MRK MERCK & CO INC 2.0%
Value $9.636M Shares 125,000 Share Price $77.09 * Est. Cost/Share $63.06 Unrealized @ Report Date 0.0%
— ALBIREO PHARMA INC 1.9%
Value $9.459M Shares 268,346 Share Price $35.25 Est. Cost/Share $33.37 Unrealized @ Report Date —
UTHR UNITED THERAPEUTICS CORP 1.9%
Value $9.374M Shares 56,044 Share Price $167.26 Est. Cost/Share $118.46 Unrealized @ Report Date +40.8%
ICLR ICON PLC 1.9%
Value $9.328M Shares 47,500 Share Price $196.38 Est. Cost/Share $197.42 Unrealized @ Report Date 0.0%
— GLAXOSMITHKLINE PLC 1.9%
Value $9.19M Shares 257,500 Share Price $35.69 Est. Cost/Share $35.69 Unrealized @ Report Date —
AMN AMN HEALTHCARE SERVICES INC 1.9%
Value $9.131M Shares 123,898 Share Price $73.70 Est. Cost/Share $52.64 Unrealized @ Report Date +41.2%
UHS UNIVERSAL HEALTH SERVICES INC 1.8%
Value $9.089M Shares 68,135 Share Price $133.40 * Est. Cost/Share $121.19 Unrealized @ Report Date +6.6%
— ESSA PHARMA INC 1.8%
Value $9.084M Shares 312,711 Share Price $29.05 Est. Cost/Share $6.90 Unrealized @ Report Date —
MIRM MIRUM PHARMACEUTICALS INC 1.8%
Value $8.664M Shares 437,138 Share Price $19.82 * Est. Cost/Share $19.66 Unrealized @ Report Date -2.6%
— BIOLINE RX LTD 1.6%
Value $7.65M Shares 2,741,776 Share Price $2.79 Est. Cost/Share $2.79 Unrealized @ Report Date —
MCK MCKESSON CORP 1.5%
Value $7.586M Shares 38,893 Share Price $195.05 * Est. Cost/Share $139.67 Unrealized @ Report Date +27.0%
— X4 PHARMACEUTICALS INC 1.4%
Value $6.928M Shares 804,597 Share Price $8.61 Est. Cost/Share $8.61 Unrealized @ Report Date —
HLF HERBALIFE NUTRITION LTD 1.3%
Value $6.597M Shares 148,719 Share Price $44.36 * Est. Cost/Share $49.20 Unrealized @ Report Date +0.2%
— CHARDAN HEALTHCARE ACQUISITION 2 CORP 1.3%
Value $6.41M Shares 600,000 Share Price $10.68 Est. Cost/Share $10.68 Unrealized @ Report Date —
TEVA TEVA PHARMACEUTICAL INDUSTRIES LTD 1.3%
Value $6.231M Shares 539,947 Share Price $11.54 Est. Cost/Share $10.34 Unrealized @ Report Date —
— VAPOTHERM INC 1.3%
Value $6.203M Shares 258,261 Share Price $24.02 Est. Cost/Share $24.87 Unrealized @ Report Date —
KURA KURA ONCOLOGY INC 1.2%
Value $6.035M Shares 213,471 Share Price $28.27 * Est. Cost/Share $30.77 Unrealized @ Report Date +2.8%
— HORIZON THERAPEUTICS PLC 1.2%
Value $5.964M Shares 64,801 Share Price $92.04 Est. Cost/Share $77.68 Unrealized @ Report Date —
CCRN CROSS COUNTRY HEALTHCARE INC 1.1%
Value $5.411M Shares 433,244 Share Price $12.49 * Est. Cost/Share $6.65 Unrealized @ Report Date +59.5%
— AYALA PHARMACEUTICALS INC 1.1%
Value $5.346M Shares 489,988 Share Price $10.91 Est. Cost/Share $10.78 Unrealized @ Report Date —
— ASLAN PHARMACEUTICALS LTD 1.0%
Value $4.853M Shares 1,448,508 Share Price $3.35 Est. Cost/Share $1.88 Unrealized @ Report Date —
— RADIUS HEALTH INC 1.0%
Value $4.818M Shares 230,957 Share Price $20.86 Est. Cost/Share $13.17 Unrealized @ Report Date —
ARDX ARDELYX INC 1.0%
Value $4.771M Shares 720,621 Share Price $6.62 * Est. Cost/Share $6.10 Unrealized @ Report Date +12.6%
NVAX NOVAVAX INC 0.9%
Value $4.66M Shares 25,700 Share Price $181.32 * Est. Cost/Share $199.27 Unrealized @ Report Date 0.0%
EBS EMERGENT BIOSOLUTIONS INC 0.9%
Value $4.646M Shares 50,000 Share Price $92.92 * Est. Cost/Share $102.42 Unrealized @ Report Date 0.0%
— SALARIUS PHARMACEUTICALS INC 0.9%
Value $4.616M Shares 3,118,696 Share Price $1.48 Est. Cost/Share $1.18 Unrealized @ Report Date —
— SYNEOS HEALTH INC 0.9%
Value $4.553M Shares 60,025 Share Price $75.85 Est. Cost/Share $53.16 Unrealized @ Report Date —
VRTX VERTEX PHARMACEUTICALS INC 0.9%
Value $4.527M Shares 21,067 Share Price $214.89 * Est. Cost/Share $229.44 Unrealized @ Report Date -4.3%
— NATUS MEDICAL INC 0.9%
Value $4.34M Shares 169,454 Share Price $25.61 Est. Cost/Share $18.43 Unrealized @ Report Date —
— AFFIMED NV 0.9%
Value $4.335M Shares 548,044 Share Price $7.91 Est. Cost/Share $7.91 Unrealized @ Report Date —
MGNX MACROGENICS INC 0.8%
Value $4.141M Shares 130,000 Share Price $31.85 * Est. Cost/Share $24.28 Unrealized @ Report Date 0.0%
— MOLECULIN BIOTECH INC 0.8%
Value $3.929M Shares 963,000 Share Price $4.08 Est. Cost/Share $4.08 Unrealized @ Report Date —
— CONSTELLATION PHARMACEUTICALS INC 0.8%
Value $3.887M Shares 166,186 Share Price $23.39 Est. Cost/Share $26.40 Unrealized @ Report Date —
VKTX VIKING THERAPEUTICS INC 0.7%
Value $3.604M Shares 569,780 Share Price $6.33 * Est. Cost/Share $8.73 Unrealized @ Report Date -19.4%
— CELLECTAR BIOSCIENCES INC 0.7%
Value $3.523M Shares 2,188,058 Share Price $1.61 Est. Cost/Share $1.59 Unrealized @ Report Date —
— PRECISION BIOSCIENCES INC 0.7%
Value $3.409M Shares 329,369 Share Price $10.35 Est. Cost/Share $7.40 Unrealized @ Report Date —
ASGN ASGN INC 0.7%
Value $3.3M Shares 34,577 Share Price $95.44 * Est. Cost/Share $76.91 Unrealized @ Report Date +20.1%
SNDX SYNDAX PHARMACEUTICALS INC 0.7%
Value $3.268M Shares 146,142 Share Price $22.36 Est. Cost/Share $20.58 Unrealized @ Report Date +9.8%
— AEGLEA BIO THERAPEUTICS INC 0.6%
Value $3.189M Shares 402,653 Share Price $7.92 Est. Cost/Share $8.55 Unrealized @ Report Date —
— CATALYST BIOSCIENCES INC 0.6%
Value $3.144M Shares 623,892 Share Price $5.04 Est. Cost/Share $7.85 Unrealized @ Report Date —
— EUCRATES BIOMEDICAL ACQUISITION CORP. 0.6%
Value $3.004M Shares 300,000 Share Price $10.01 Est. Cost/Share $10.66 Unrealized @ Report Date —
— NEUBASE THERAPEUTICS INC 0.6%
Value $2.909M Shares 393,699 Share Price $7.39 Est. Cost/Share $8.06 Unrealized @ Report Date —
— HEALTH SCIENCES ACQUISITIONS CORP 2 0.6%
Value $2.798M Shares 250,000 Share Price $11.19 Est. Cost/Share $11.00 Unrealized @ Report Date —
LRMR LARIMAR THERAPEUTICS INC 0.6%
Value $2.735M Shares 187,223 Share Price $14.61 * Est. Cost/Share $11.65 Unrealized @ Report Date +56.0%
— ONCTERNAL THERAPEUTICS INC 0.5%
Value $2.69M Shares 323,333 Share Price $8.32 Est. Cost/Share $4.90 Unrealized @ Report Date —
— FUSION PHARMACEUTICALS INC 0.5%
Value $2.674M Shares 249,419 Share Price $10.72 Est. Cost/Share $11.43 Unrealized @ Report Date —
PRQR PROQR THERAPEUTICS NV 0.5%
Value $2.597M Shares 392,821 Share Price $6.61 * Est. Cost/Share $5.11 Unrealized @ Report Date 0.0%
— CYMABAY THERAPEUTICS INC 0.5%
Value $2.553M Shares 562,339 Share Price $4.54 Est. Cost/Share $3.37 Unrealized @ Report Date —
— MERSANA THERAPEUTICS INC 0.5%
Value $2.544M Shares 157,259 Share Price $16.18 Est. Cost/Share $15.50 Unrealized @ Report Date —
GOSS GOSSAMER BIO INC 0.5%
Value $2.418M Shares 261,400 Share Price $9.25 * Est. Cost/Share $10.08 Unrealized @ Report Date 0.0%
FULC FULCRUM THERAPEUTICS INC 0.5%
Value $2.253M Shares 191,272 Share Price $11.78 * Est. Cost/Share $11.55 Unrealized @ Report Date +7.0%
— VINCERX PHARMA INC 0.4%
Value $2.027M Shares 105,000 Share Price $19.30 Est. Cost/Share $20.91 Unrealized @ Report Date —
LLY ELI LILLY AND CO 0.4%
Value $1.793M Shares 9,600 Share Price $186.77 Est. Cost/Share — Unrealized @ Report Date —
— ATRECA INC 0.4%
Value $1.739M Shares 113,455 Share Price $15.33 Est. Cost/Share $15.06 Unrealized @ Report Date —
RVLPQ OSMOTICA PHARMACEUTICALS PLC 0.3%
Value $1.692M Shares 519,039 Share Price $3.26 * Est. Cost/Share $4.11 Unrealized @ Report Date 0.0%
— CERECOR INC 0.3%
Value $1.668M Shares 552,241 Share Price $3.02 Est. Cost/Share $2.59 Unrealized @ Report Date —
ANIK ANIKA THERAPEUTICS INC 0.3%
Value $1.632M Shares 40,000 Share Price $40.80 * Est. Cost/Share $34.91 Unrealized @ Report Date +8.7%
— RUBIUS THERAPEUTICS INC 0.3%
Value $1.585M Shares 59,800 Share Price $26.51 Est. Cost/Share $26.51 Unrealized @ Report Date —
— FREQUENCY THERAPEUTICS INC 0.3%
Value $1.549M Shares 163,100 Share Price $9.50 Est. Cost/Share — Unrealized @ Report Date —
— ARENA PHARMACEUTICALS INC 0.3%
Value $1.508M Shares 21,738 Share Price $69.37 Est. Cost/Share $47.41 Unrealized @ Report Date —
— MEI PHARMA INC 0.3%
Value $1.461M Shares 426,047 Share Price $3.43 Est. Cost/Share $3.06 Unrealized @ Report Date —
HROW HARROW HEALTH INC 0.3%
Value $1.415M Shares 209,623 Share Price $6.75 * Est. Cost/Share $4.97 Unrealized @ Report Date +64.8%
IOVA IOVANCE BIOTHERAPEUTICS INC 0.3%
Value $1.407M Shares 44,430 Share Price $31.67 * Est. Cost/Share $39.70 Unrealized @ Report Date +4.4%
— SIERRA ONCOLOGY INC 0.3%
Value $1.395M Shares 80,952 Share Price $17.23 Est. Cost/Share $16.24 Unrealized @ Report Date —
— ALPHA HEALTHCARE ACQUISITION CORP 0.3%
Value $1.25M Shares 100,000 Share Price $12.50 Est. Cost/Share $9.92 Unrealized @ Report Date —
— SIO GENE THERAPIES INC 0.2%
Value $1.201M Shares 460,248 Share Price $2.61 Est. Cost/Share $2.78 Unrealized @ Report Date —
ETON ETON PHARMACEUTICALS INC 0.2%
Value $1.191M Shares 162,659 Share Price $7.32 * Est. Cost/Share $8.53 Unrealized @ Report Date 0.0%
IDYA IDEAYA BIOSCIENCES INC 0.2%
Value $1.135M Shares 48,298 Share Price $23.50 * Est. Cost/Share $7.88 Unrealized @ Report Date +145.1%
— GLYCOMIMETICS INC 0.2%
Value $1.07M Shares 355,517 Share Price $3.01 Est. Cost/Share $3.01 Unrealized @ Report Date —
NBP I-MAB 0.1%
Value $727K Shares 15,000 Share Price $48.47 Est. Cost/Share $13.00 Unrealized @ Report Date —
— DEERFIELD HEALTHCARE TECHNOLOGY ACQUISITIONS CORP 0.1%
Value $655K Shares 50,000 Share Price $13.10 Est. Cost/Share $10.64 Unrealized @ Report Date —
— CASI PHARMACEUTICALS INC 0.1%
Value $488K Shares 203,432 Share Price $2.40 Est. Cost/Share $1.53 Unrealized @ Report Date —
— NEOLEUKIN THERAPEUTICS INC 0.1%
Value $472K Shares 38,312 Share Price $12.32 Est. Cost/Share $12.32 Unrealized @ Report Date —
— MESOBLAST LTD 0.1%
Value $468K Shares 56,600 Share Price $8.27 Est. Cost/Share — Unrealized @ Report Date —
— RAPT THERAPEUTICS INC 0.1%
Value $317K Shares 14,298 Share Price $22.17 Est. Cost/Share $21.26 Unrealized @ Report Date —
— APTOSE BIOSCIENCES INC 0.0%
Value $246K Shares 41,100 Share Price $5.99 Est. Cost/Share $5.99 Unrealized @ Report Date —
— BIONANO GENOMICS INC 0.0%
Value $196K Shares 24,245 Share Price $8.08 Est. Cost/Share $8.08 Unrealized @ Report Date —
— TRILLIUM THERAPEUTICS INC 0.0%
Value $166K Shares 15,500 Share Price $10.71 Est. Cost/Share $14.71 Unrealized @ Report Date —