Location: San Diego, CA
CIK: 0001232621 · Show all filings
Period: Q3 2023 (← Previous) (Next →)
Filing Date: Nov 14, 2023
Total Value: $709M (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| TARS | TARSUS PHARMACEUTICALS INC | 2,140,586 | $38.04M | 5.4% | $17.77 | $15.88 | +11.4% | COM | 87650L103 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,137,107 | $35.93M | 5.1% | $31.60 * | $21.51 | +27.3% | COM | 604749101 |
| ANAB | ANAPTYSBIO INC | 1,950,609 | $35.03M | 4.9% | $17.96 * | $21.51 | -11.3% | COM | 032724106 |
| KALV | KALVISTA PHARMACEUTICALS INC | 3,440,345 | $33.13M | 4.7% | $9.63 * | $9.46 | +8.0% | COM | 483497103 |
| EOLS | EVOLUS INC | 3,097,399 | $28.31M | 4.0% | $9.14 | $8.75 | +2.5% | COM | 30052C107 |
| — | IMMUNOGEN INC | 1,500,000 | $23.8M | 3.4% | $15.87 | $8.74 | — | COM | 45253H101 |
| — | EQRX INC | 10,086,110 | $22.39M | 3.2% | $2.22 | $2.22 | — | COM | 26886C107 |
| AXSM | AXSOME THERAPEUTICS INC | 320,000 | $22.36M | 3.2% | $69.89 * | $57.63 | +29.7% | COM | 05464T104 |
| IMCR | IMMUNOCORE HLDGS PLC | 405,600 | $21.05M | 3.0% | $51.90 | $30.74 | — | ADS | 45258D105 |
| — | NEW YORK CMNTY BANCORP INC | 1,606,600 | $18.22M | 2.6% | $11.34 | $9.04 | — | COM | 649445103 |
| LLY | ELI LILLY & CO | 30,000 | $16.11M | 2.3% | $537.13 * | $340.49 | +48.8% | COM | 532457108 |
| — | INTRA-CELLULAR THERAPIES INC | 300,000 | $15.63M | 2.2% | $52.09 | $59.78 | — | COM | 46116X101 |
| PCVX | VAXCYTE INC | 300,000 | $15.29M | 2.2% | $50.98 * | $39.24 | +25.7% | COM | 92243G108 |
| ONC | BEIGENE LTD | 85,000 | $15.29M | 2.2% | $179.87 | $134.82 | — | SPONSORED ADR | 07725L102 |
| — | BLUEBIRD BIO INC | 4,282,827 | $13.02M | 1.8% | $3.04 | $3.78 | — | COM | 09609G100 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 1,800,000 | $12.74M | 1.8% | $7.08 | $9.70 | -25.9% | COM | 09058V103 |
| NTLA | INTELLIA THERAPEUTICS INC | 397,600 | $12.57M | 1.8% | $31.62 * | $38.80 | 0.0% | COM | 45826J105 |
| AZN | ASTRAZENECA PLC | 170,000 | $11.51M | 1.6% | $67.72 | $56.36 | — | SPONSORED ADR | 046353108 |
| — | THIRD HARMONIC BIO INC | 1,800,000 | $11.5M | 1.6% | $6.39 | $4.29 | — | COM | 88427A107 |
| AVIR | ATEA PHARMACEUTICALS INC | 3,600,000 | $10.8M | 1.5% | $3.00 * | $3.78 | -9.9% | COM | 04683R106 |
| — | KINIKSA PHARMACEUTICALS LTD | 600,000 | $10.42M | 1.5% | $17.37 | $9.90 | — | COM CL A | G5269C101 |
| — | AVADEL PHARMACEUTICALS PLC | 1,000,000 | $10.3M | 1.5% | $10.30 | $10.30 | — | SPONSORED ADR | 05337M104 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 669,125 | $10.26M | 1.4% | $15.34 * | $15.92 | +19.8% | COM | 92790C104 |
| IONS | IONIS PHARMACEUTICALS INC | 200,000 | $9.072M | 1.3% | $45.36 * | $32.73 | +26.0% | COM | 462222100 |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | 271,200 | $8.887M | 1.3% | $32.77 * | $41.60 | -16.6% | COM | 413197104 |
| BIO | BIO RAD LABS INC | 24,000 | $8.603M | 1.2% | $358.45 * | $508.83 | -24.2% | CL A | 090572207 |
| IFRX | INFLARX NV | 2,824,353 | $8.417M | 1.2% | $2.98 * | $4.48 | -15.0% | COM | N44821101 |
| CTMX | CYTOMX THERAPEUTICS INC | 6,450,000 | $8.32M | 1.2% | $1.29 * | $1.89 | -16.7% | COM | 23284F105 |
| DNTH | DIANTHUS THERAPEUTICS INC | 591,636 | $8.088M | 1.1% | $13.67 * | $12.62 | 0.0% | COM | 252828108 |
| NVCR | NOVOCURE LTD | 492,100 | $7.947M | 1.1% | $16.15 * | $35.59 | -19.0% | ORD SHS | G6674U108 |
| MRNA | MODERNA INC | 76,700 | $7.922M | 1.1% | $103.29 * | $164.11 | -32.0% | COM | 60770K107 |
| — | MIRATI THERAPEUTICS INC | 180,000 | $7.841M | 1.1% | $43.56 | $40.26 | — | COM | 60468T105 |
| VSTM | VERASTEM INC | 891,514 | $7.248M | 1.0% | $8.13 * | $6.94 | +38.4% | COM NEW | 92337C203 |
| ALT | ALTIMMUNE INC | 2,750,000 | $7.15M | 1.0% | $2.60 * | $9.59 | -70.1% | COM NEW | 02155H200 |
| ZYME | ZYMEWORKS INC | 1,100,000 | $6.974M | 1.0% | $6.34 * | $8.10 | -8.9% | COM | 98985Y108 |
| BCAB | BIOATLA INC | 3,778,393 | $6.423M | 0.9% | $1.70 * | $6.46 | -60.6% | COM | 09077B104 |
| QURE | UNIQURE NV | 935,800 | $6.279M | 0.9% | $6.71 * | $9.00 | 0.0% | SHS | N90064101 |
| AUPH | AURINIA PHARMACEUTICALS INC | 750,000 | $5.827M | 0.8% | $7.77 * | $9.90 | -1.2% | COM | 05156V102 |
| CGEM | CULLINAN ONCOLOGY INC | 621,138 | $5.621M | 0.8% | $9.05 * | $11.25 | -7.4% | COM | 230031106 |
| — | EQUITY COMWLTH | 300,000 | $5.511M | 0.8% | $18.37 | $19.15 | — | COM SH BEN INT | 294628102 |
| — | AVROBIO INC | 3,512,686 | $5.41M | 0.8% | $1.54 | $1.09 | — | COM | 05455M100 |
| — | AMARIN CORP PLC | 5,862,517 | $5.394M | 0.8% | $0.92 | $1.43 | — | SPONS ADR NEW | 023111206 |
| — | GRAPHITE BIO INC | 2,016,626 | $5.001M | 0.7% | $2.48 | $2.61 | — | COM | 38870X104 |
| ADMA | ADMA BIOLOGICS INC | 1,360,000 | $4.869M | 0.7% | $3.58 * | $3.72 | +3.6% | COM | 000899104 |
| — | DYNAVAX TECHNOLOGIES CORP | 300,000 | $4.431M | 0.6% | $14.77 | $10.57 | — | COM NEW | 268158201 |
| INSM | INSMED INC | 166,203 | $4.197M | 0.6% | $25.25 * | $23.98 | -4.6% | COM PAR $.01 | 457669307 |
| C | CITIGROUP INC | 100,000 | $4.113M | 0.6% | $41.13 | $44.28 | -8.6% | COM NEW | 172967424 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 5,166,954 | $4.03M | 0.6% | $0.78 | $0.92 | — | SPONDS ADR | 00653A107 |
| QNCX | QUINCE THERAPEUTICS INC | 3,498,868 | $3.919M | 0.6% | $1.12 * | $0.98 | +33.5% | COM | 22053A107 |
| — | VERITEX HLDGS INC | 210,000 | $3.769M | 0.5% | $17.95 | $18.10 | — | COM | 923451108 |
| — | BOLT BIOTHERAPEUTICS INC | 3,557,040 | $3.699M | 0.5% | $1.04 | $1.35 | — | COM | 097702104 |
| BHVN | BIOHAVEN LTD | 140,000 | $3.641M | 0.5% | $26.01 * | $14.12 | +47.2% | COM | G1110E107 |
| — | ASLAN PHARMACEUTICALS LTD | 1,901,552 | $3.575M | 0.5% | $1.88 | $2.47 | — | SPON ADS NEW | 04522R200 |
| GNFTY | GENFIT S A | 1,040,636 | $3.403M | 0.5% | $3.27 | $4.75 | — | ADS | 372279109 |
| CVBF | CVB FINL CORP | 200,000 | $3.314M | 0.5% | $16.57 * | $19.92 | -23.5% | COM | 126600105 |
| USB | US BANCORP DEL | 100,000 | $3.306M | 0.5% | $33.06 | $28.41 | +14.4% | COM NEW | 902973304 |
| — | RAIN ONCOLOGY INC | 3,740,341 | $3.223M | 0.5% | $0.86 | $1.20 | — | COM | 75082Q105 |
| DSGN | DESIGN THERAPEUTICS INC | 1,350,000 | $3.186M | 0.4% | $2.36 * | $4.66 | 0.0% | COM | 25056L103 |
| GLPG | GALAPAGOS NV | 89,650 | $3.097M | 0.4% | $34.55 | $62.02 | — | SPON ADR | 36315X101 |
| — | ENZO BIOCHEM INC | 2,200,000 | $3.08M | 0.4% | $1.40 | $2.43 | — | COM | 294100102 |
| RCKT | ROCKET PHARMACEUTICALS INC | 150,000 | $3.074M | 0.4% | $20.49 * | $18.18 | 0.0% | COM | 77313F106 |
| — | CYMABAY THERAPEUTICS INC | 200,000 | $2.982M | 0.4% | $14.91 | $14.91 | — | COM | 23257D103 |
| LIANY | LIANBIO | 1,800,000 | $2.682M | 0.4% | $1.49 | $1.86 | — | SPONSORED ADS | 53000N108 |
| — | ELEVATION ONCOLOGY INC | 4,000,000 | $2.65M | 0.4% | $0.66 | $1.54 | — | COM | 28623U101 |
| — | ALIGOS THERAPEUTICS INC | 3,329,048 | $2.487M | 0.4% | $0.75 | $1.06 | — | COM | 01626L105 |
| — | NEKTAR THERAPEUTICS | 3,939,600 | $2.346M | 0.3% | $0.60 | $0.77 | — | COM | 640268108 |
| LITS | MEI PHARMA INC | 326,084 | $2.286M | 0.3% | $7.01 * | $4.94 | +3.2% | COM | 55279B301 |
| TNGX | TANGO THERAPEUTICS INC | 200,000 | $2.252M | 0.3% | $11.26 * | $5.80 | +5.1% | COM | 87583X109 |
| ACAD | ACADIA PHARMACEUTICALS INC | 100,000 | $2.084M | 0.3% | $20.84 * | $27.16 | 0.0% | COM | 004225108 |
| PDSB | PDS BIOTECHNOLOGY CORP | 400,000 | $2.02M | 0.3% | $5.05 * | $5.75 | -4.7% | COM | 70465T107 |
| HRTX | HERON THERAPEUTICS INC | 1,850,000 | $1.905M | 0.3% | $1.03 * | $4.36 | -67.3% | COM | 427746102 |
| — | BIONOMICS LIMITED | 700,000 | $1.89M | 0.3% | $2.70 | $2.70 | — | ADS | 09063M205 |
| EGRX | EAGLE PHARMACEUTICALS INC | 118,857 | $1.874M | 0.3% | $15.77 * | $32.45 | -44.6% | COM | 269796108 |
| ESPR | ESPERION THERAPEUTICS INC NE | 1,850,000 | $1.813M | 0.3% | $0.98 * | $5.16 | -72.0% | COM | 29664W105 |
| — | KARUNA THERAPEUTICS INC | 10,000 | $1.691M | 0.2% | $169.09 | $169.09 | — | COM | 48576A100 |
| — | ADICET BIO INC | 1,226,352 | $1.68M | 0.2% | $1.37 | $6.52 | — | COM | 007002108 |
| DERM | JOURNEY MED CORP | 576,100 | $1.579M | 0.2% | $2.74 * | $2.23 | 0.0% | COM | 48115J109 |
| ARVN | ARVINAS INC | 80,000 | $1.571M | 0.2% | $19.64 * | $37.14 | -33.9% | COM | 04335A105 |
| SFBS | SERVISFIRST BANCSHARES INC | 30,000 | $1.565M | 0.2% | $52.17 * | $63.35 | -20.1% | COM | 81768T108 |
| EDIT | EDITAS MEDICINE INC | 200,000 | $1.56M | 0.2% | $7.80 * | $8.71 | -1.6% | COM | 28106W103 |
| SPRY | ARS PHARMACEUTICALS INC | 409,463 | $1.548M | 0.2% | $3.78 * | $4.93 | +33.2% | COM | 82835W108 |
| NKTX | NKARTA INC | 1,103,638 | $1.534M | 0.2% | $1.39 * | $11.10 | -82.9% | COM | 65487U108 |
| CHRS | COHERUS BIOSCIENCES INC | 400,000 | $1.496M | 0.2% | $3.74 * | $9.57 | -51.7% | COM | 19249H103 |
| BOH | BANK HAWAII CORP | 30,000 | $1.491M | 0.2% | $49.69 * | $38.82 | +18.0% | COM | 062540109 |
| FATE | FATE THERAPEUTICS INC | 700,000 | $1.484M | 0.2% | $2.12 * | $6.03 | -45.1% | COM | 31189P102 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 400,000 | $1.148M | 0.2% | $2.87 * | $3.68 | 0.0% | COM | 09203E105 |
| ASND | ASCENDIS PHARMA A/S | 10,000 | $936K | 0.1% | $93.64 | $89.25 | — | SPONSORED ADR | 04351P101 |
| TGTX | TG THERAPEUTICS INC | 100,000 | $836K | 0.1% | $8.36 * | $13.94 | 0.0% | COM | 88322Q108 |
| ATYR | ATYR PHARMA INC | 471,134 | $744K | 0.1% | $1.58 * | $2.95 | -37.3% | COM NEW | 002120202 |
| — | ATHIRA PHARMA INC | 352,715 | $712K | 0.1% | $2.02 | $3.17 | — | COM | 04746L104 |
| GOSS | GOSSAMER BIO INC | 838,600 | $698K | 0.1% | $0.83 * | $1.15 | 0.0% | COM | 38341P102 |
| MASS | 908 DEVICES INC | 100,000 | $666K | 0.1% | $6.66 * | $8.04 | -13.9% | COM | 65443P102 |
| IVVD | INVIVYD INC | 366,536 | $623K | 0.1% | $1.70 * | $1.47 | +8.3% | COM | 00534A102 |
| — | INSPIRATO INCORPORATED | 875,577 | $517K | 0.1% | $0.59 | $0.97 | — | COM CL A | 45791E107 |
| — | NEXTCURE INC | 400,000 | $516K | 0.1% | $1.29 | $1.48 | — | COM | 65343E108 |
| — | GRACELL BIOTECHNOLOGIES INC | 159,087 | $458K | 0.1% | $2.88 | $2.88 | — | SPONSORED ADS | 38406L103 |
| STEL | STELLAR BANCORP INC | 20,000 | $426K | 0.1% | $21.32 * | $25.71 | -11.3% | COM | 858927106 |
| — | SELECTA BIOSCIENCES INC | 400,000 | $424K | 0.1% | $1.06 | $1.12 | — | COM | 816212104 |
| MOLN | MOLECULAR PARTNERS AG | 100,000 | $414K | 0.1% | $4.14 | $5.03 | — | ADS | 60853G106 |
| EQ | EQUILLIUM INC | 400,000 | $296K | 0.0% | $0.74 * | $0.73 | +10.3% | COM | 29446K106 |
| XERS | XERIS BIOPHARMA HOLDINGS INC | 150,000 | $279K | 0.0% | $1.86 * | $2.29 | 0.0% | COM | 98422E103 |
| STIM | NEURONETICS INC | 200,000 | $270K | 0.0% | $1.35 * | $2.43 | -27.8% | COM | 64131A105 |
| — | PASSAGE BIO INC | 400,000 | $263K | 0.0% | $0.66 | $0.88 | — | COM | 702712100 |
| WGS | GENEDX HOLDINGS CORP | 63,636 | $232K | 0.0% | $3.64 * | $7.91 | -30.8% | COM CL A | 81663L200 |
| TLPH | ACELRX PHARMACEUTICALS INC | 195,000 | $113K | 0.0% | $0.58 * | $2.81 | -66.0% | COM NEW | 00444T209 |
| — | TRANSCODE THERAPEUTICS INC | 84,010 | $42,232 | 0.0% | $0.50 | $0.50 | — | COM NEW | 89357L204 |