TANG CAPITAL MANAGEMENT LLC Diversified Active

Location: San Diego, CA

CIK: 0001232621 · Show all filings

Period: Q1 2024 (← Previous) (Next →)

Filing Date: May 15, 2024

Total Value: $960M (100.0% shares, 0.0% debt)

Holdings (99)

TARS TARSUS PHARMACEUTICALS INC 8.5%
Value $81.96M Shares 2,254,797 Share Price $36.35 * Est. Cost/Share $16.20 Unrealized @ Report Date +81.5%
EOLS EVOLUS INC 6.0%
Value $58.06M Shares 4,147,399 Share Price $14.00 * Est. Cost/Share $9.82 Unrealized @ Report Date +32.3%
KALV KALVISTA PHARMACEUTICALS INC 5.1%
Value $48.93M Shares 4,125,345 Share Price $11.86 * Est. Cost/Share $10.10 Unrealized @ Report Date +32.0%
ANAB ANAPTYSBIO INC 3.1%
Value $29.97M Shares 1,330,879 Share Price $22.52 * Est. Cost/Share $21.51 Unrealized @ Report Date +10.1%
MIRM MIRUM PHARMACEUTICALS INC 3.1%
Value $29.82M Shares 1,187,107 Share Price $25.12 * Est. Cost/Share $21.76 Unrealized @ Report Date +26.3%
ALT ALTIMMUNE INC 2.9%
Value $28M Shares 2,750,000 Share Price $10.18 Est. Cost/Share $9.59 Unrealized @ Report Date +6.1%
IMCR IMMUNOCORE HLDGS PLC 2.7%
Value $26.36M Shares 405,600 Share Price $65.00 Est. Cost/Share $30.74 Unrealized @ Report Date —
— INHIBRX INC 2.5%
Value $24.47M Shares 700,000 Share Price $34.96 Est. Cost/Share $34.96 Unrealized @ Report Date —
LLY ELI LILLY & CO 2.2%
Value $21M Shares 27,000 Share Price $777.96 * Est. Cost/Share $340.49 Unrealized @ Report Date +106.3%
PCVX VAXCYTE INC 2.1%
Value $20.49M Shares 300,000 Share Price $68.31 Est. Cost/Share $39.24 Unrealized @ Report Date +76.5%
PTCT PTC THERAPEUTICS INC 2.1%
Value $20.36M Shares 700,000 Share Price $29.09 * Est. Cost/Share $22.87 Unrealized @ Report Date +22.5%
OTLK OUTLOOK THERAPEUTICS INC 2.0%
Value $19.34M Shares 1,619,412 Share Price $11.94 * Est. Cost/Share $8.09 Unrealized @ Report Date 0.0%
RCKT ROCKET PHARMACEUTICALS INC 1.9%
Value $17.78M Shares 660,000 Share Price $26.94 * Est. Cost/Share $25.12 Unrealized @ Report Date +13.1%
IMNM IMMUNOME INC 1.9%
Value $17.77M Shares 720,000 Share Price $24.68 * Est. Cost/Share $20.29 Unrealized @ Report Date 0.0%
— AVADEL PHARMACEUTICALS PLC 1.8%
Value $17.69M Shares 1,047,275 Share Price $16.89 Est. Cost/Share $10.58 Unrealized @ Report Date —
VTYX VENTYX BIOSCIENCES INC 1.8%
Value $17.05M Shares 3,100,000 Share Price $5.50 * Est. Cost/Share $7.75 Unrealized @ Report Date -41.0%
AVIR ATEA PHARMACEUTICALS INC 1.7%
Value $16.47M Shares 4,076,741 Share Price $4.04 * Est. Cost/Share $3.69 Unrealized @ Report Date +6.1%
— ELEVATION ONCOLOGY INC 1.6%
Value $15.7M Shares 3,060,000 Share Price $5.13 Est. Cost/Share $1.54 Unrealized @ Report Date —
— APPLIED THERAPEUTICS INC 1.6%
Value $15.16M Shares 2,230,000 Share Price $6.80 Est. Cost/Share $6.80 Unrealized @ Report Date —
— ADICET BIO INC 1.6%
Value $15.06M Shares 6,407,400 Share Price $2.35 Est. Cost/Share $2.92 Unrealized @ Report Date —
— MORPHOSYS AG 1.5%
Value $14.52M Shares 800,705 Share Price $18.14 Est. Cost/Share $18.14 Unrealized @ Report Date —
CTMX CYTOMX THERAPEUTICS INC 1.5%
Value $14.06M Shares 6,450,000 Share Price $2.18 * Est. Cost/Share $1.88 Unrealized @ Report Date -1.9%
NUVB NUVATION BIO INC 1.3%
Value $12.93M Shares 3,551,864 Share Price $3.64 * Est. Cost/Share $1.30 Unrealized @ Report Date +48.2%
GSK GSK PLC 1.3%
Value $12.86M Shares 300,000 Share Price $42.87 Est. Cost/Share $37.06 Unrealized @ Report Date —
LENZ LENZ THERAPEUTICS INC 1.3%
Value $12.23M Shares 547,616 Share Price $22.33 * Est. Cost/Share $20.79 Unrealized @ Report Date 0.0%
VRDN VIRIDIAN THERAPEUTICS INC 1.3%
Value $12.13M Shares 692,925 Share Price $17.51 * Est. Cost/Share $15.92 Unrealized @ Report Date +21.8%
ZYME ZYMEWORKS INC 1.2%
Value $11.57M Shares 1,100,000 Share Price $10.52 * Est. Cost/Share $8.10 Unrealized @ Report Date +37.0%
— CARGO THERAPEUTICS INC 1.1%
Value $10.42M Shares 466,809 Share Price $22.32 Est. Cost/Share $22.61 Unrealized @ Report Date —
— INTRA-CELLULAR THERAPIES INC 1.1%
Value $10.38M Shares 150,000 Share Price $69.20 Est. Cost/Share $59.78 Unrealized @ Report Date —
ANIP ANI PHARMACEUTICALS INC 1.1%
Value $10.37M Shares 150,000 Share Price $69.13 * Est. Cost/Share $60.37 Unrealized @ Report Date 0.0%
AUPH AURINIA PHARMACEUTICALS INC 1.1%
Value $10.27M Shares 2,050,000 Share Price $5.01 * Est. Cost/Share $7.62 Unrealized @ Report Date -11.0%
AZN ASTRAZENECA PLC 1.1%
Value $10.16M Shares 150,000 Share Price $67.75 Est. Cost/Share $56.36 Unrealized @ Report Date —
— KINIKSA PHARMACEUTICALS LTD 1.0%
Value $9.865M Shares 500,000 Share Price $19.73 Est. Cost/Share $9.90 Unrealized @ Report Date —
CGEM CULLINAN ONCOLOGY INC 1.0%
Value $9.732M Shares 571,138 Share Price $17.04 * Est. Cost/Share $10.78 Unrealized @ Report Date +43.3%
ACAD ACADIA PHARMACEUTICALS INC 1.0%
Value $9.594M Shares 518,900 Share Price $18.49 * Est. Cost/Share $25.21 Unrealized @ Report Date -1.7%
HRMY HARMONY BIOSCIENCES HLDGS IN 1.0%
Value $9.443M Shares 281,200 Share Price $33.58 * Est. Cost/Share $41.26 Unrealized @ Report Date -22.2%
— DECIPHERA PHARMACEUTICALS IN 1.0%
Value $9.438M Shares 600,000 Share Price $15.73 Est. Cost/Share $15.73 Unrealized @ Report Date —
NVDA NVIDIA CORPORATION 0.9%
Value $9.036M Shares 10,000 Share Price $903.56 * Est. Cost/Share $72.44 Unrealized @ Report Date 0.0%
VKTX VIKING THERAPEUTICS INC 0.9%
Value $8.2M Shares 100,000 Share Price $82.00 * Est. Cost/Share $44.50 Unrealized @ Report Date 0.0%
BDTX BLACK DIAMOND THERAPEUTICS I 0.8%
Value $8.128M Shares 1,603,200 Share Price $5.07 * Est. Cost/Share $2.64 Unrealized @ Report Date +52.6%
DTIL PRECISION BIOSCIENCES INC 0.8%
Value $7.995M Shares 589,569 Share Price $13.56 * Est. Cost/Share $12.24 Unrealized @ Report Date 0.0%
DNTH DIANTHUS THERAPEUTICS INC 0.8%
Value $7.941M Shares 264,692 Share Price $30.00 * Est. Cost/Share $12.62 Unrealized @ Report Date +72.3%
CRSP CRISPR THERAPEUTICS AG 0.8%
Value $7.941M Shares 116,500 Share Price $68.16 * Est. Cost/Share $55.02 Unrealized @ Report Date +30.1%
BHVN BIOHAVEN LTD 0.8%
Value $7.657M Shares 140,000 Share Price $54.69 * Est. Cost/Share $14.12 Unrealized @ Report Date +250.7%
ARVN ARVINAS INC 0.8%
Value $7.43M Shares 180,000 Share Price $41.28 * Est. Cost/Share $40.78 Unrealized @ Report Date +7.1%
IOVA IOVANCE BIOTHERAPEUTICS INC 0.8%
Value $7.41M Shares 500,000 Share Price $14.82 * Est. Cost/Share $5.23 Unrealized @ Report Date +122.4%
VNDA VANDA PHARMACEUTICALS INC 0.7%
Value $7.199M Shares 1,751,654 Share Price $4.11 * Est. Cost/Share $4.01 Unrealized @ Report Date -0.1%
CYTK CYTOKINETICS INC 0.7%
Value $7.011M Shares 100,000 Share Price $70.11 * Est. Cost/Share $36.21 Unrealized @ Report Date +113.6%
APGE APOGEE THERAPEUTICS INC 0.7%
Value $6.645M Shares 100,000 Share Price $66.45 * Est. Cost/Share $43.66 Unrealized @ Report Date 0.0%
IONS IONIS PHARMACEUTICALS INC 0.7%
Value $6.503M Shares 150,000 Share Price $43.35 * Est. Cost/Share $32.73 Unrealized @ Report Date +45.6%
VSTM VERASTEM INC 0.7%
Value $6.39M Shares 541,514 Share Price $11.80 * Est. Cost/Share $6.94 Unrealized @ Report Date +66.5%
DSGN DESIGN THERAPEUTICS INC 0.6%
Value $5.968M Shares 1,480,975 Share Price $4.03 * Est. Cost/Share $4.45 Unrealized @ Report Date -40.0%
NKTX NKARTA INC 0.6%
Value $5.946M Shares 550,000 Share Price $10.81 * Est. Cost/Share $11.10 Unrealized @ Report Date -6.4%
ONC BEIGENE LTD 0.6%
Value $5.786M Shares 37,000 Share Price $156.39 Est. Cost/Share $134.82 Unrealized @ Report Date —
NTLA INTELLIA THERAPEUTICS INC 0.6%
Value $5.502M Shares 200,000 Share Price $27.51 Est. Cost/Share $38.80 Unrealized @ Report Date -28.4%
ENTA ENANTA PHARMACEUTICALS INC 0.5%
Value $5.238M Shares 300,000 Share Price $17.46 * Est. Cost/Share $9.32 Unrealized @ Report Date +42.0%
FATE FATE THERAPEUTICS INC 0.5%
Value $5.138M Shares 700,000 Share Price $7.34 * Est. Cost/Share $6.03 Unrealized @ Report Date +2.6%
HRTX HERON THERAPEUTICS INC 0.5%
Value $5.125M Shares 1,850,000 Share Price $2.77 * Est. Cost/Share $4.36 Unrealized @ Report Date -42.3%
BCAB BIOATLA INC 0.5%
Value $5.071M Shares 1,474,076 Share Price $3.44 * Est. Cost/Share $6.46 Unrealized @ Report Date -61.6%
— RENEO PHARMACEUTICALS INC 0.5%
Value $4.975M Shares 2,997,000 Share Price $1.66 Est. Cost/Share $1.60 Unrealized @ Report Date —
META META PLATFORMS INC 0.5%
Value $4.856M Shares 10,000 Share Price $485.58 * Est. Cost/Share $443.21 Unrealized @ Report Date 0.0%
— BOLT BIOTHERAPEUTICS INC 0.5%
Value $4.788M Shares 3,420,000 Share Price $1.40 Est. Cost/Share $1.34 Unrealized @ Report Date —
GPCR STRUCTURE THERAPEUTICS INC 0.4%
Value $4.286M Shares 100,000 Share Price $42.86 Est. Cost/Share $42.86 Unrealized @ Report Date —
BCRX BIOCRYST PHARMACEUTICALS INC 0.4%
Value $4.064M Shares 800,000 Share Price $5.08 * Est. Cost/Share $9.70 Unrealized @ Report Date -42.0%
IPSC CENTURY THERAPEUTICS INC 0.4%
Value $3.762M Shares 900,000 Share Price $4.18 Est. Cost/Share $1.82 Unrealized @ Report Date +132.3%
— BLUEBIRD BIO INC 0.3%
Value $3.2M Shares 2,500,000 Share Price $1.28 Est. Cost/Share $2.98 Unrealized @ Report Date —
QNCX QUINCE THERAPEUTICS INC 0.3%
Value $3.125M Shares 2,947,652 Share Price $1.06 * Est. Cost/Share $0.98 Unrealized @ Report Date +27.0%
— EQUITY COMWLTH 0.3%
Value $3.12M Shares 165,261 Share Price $18.88 Est. Cost/Share $19.15 Unrealized @ Report Date —
LNTH LANTHEUS HLDGS INC 0.3%
Value $3.112M Shares 50,000 Share Price $62.24 * Est. Cost/Share $58.85 Unrealized @ Report Date 0.0%
GMAB GENMAB A/S 0.3%
Value $2.991M Shares 100,000 Share Price $29.91 Est. Cost/Share $29.91 Unrealized @ Report Date —
— MIND MEDICINE MINDMED INC 0.3%
Value $2.82M Shares 300,000 Share Price $9.40 Est. Cost/Share $9.40 Unrealized @ Report Date —
— KINNATE BIOPHARMA INC 0.3%
Value $2.6M Shares 977,626 Share Price $2.66 Est. Cost/Share $2.37 Unrealized @ Report Date —
— ATHIRA PHARMA INC 0.2%
Value $2.336M Shares 852,715 Share Price $2.74 Est. Cost/Share $2.66 Unrealized @ Report Date —
ADAPY ADAPTIMMUNE THERAPEUTICS PLC 0.2%
Value $2.281M Shares 1,443,619 Share Price $1.58 Est. Cost/Share $0.92 Unrealized @ Report Date —
— AMARIN CORP PLC 0.2%
Value $2.227M Shares 2,500,000 Share Price $0.89 Est. Cost/Share $1.43 Unrealized @ Report Date —
LQDA LIQUIDIA CORPORATION 0.2%
Value $2.212M Shares 150,000 Share Price $14.75 * Est. Cost/Share $13.90 Unrealized @ Report Date 0.0%
KURA KURA ONCOLOGY INC 0.2%
Value $2.133M Shares 100,000 Share Price $21.33 * Est. Cost/Share $19.44 Unrealized @ Report Date 0.0%
— PASSAGE BIO INC 0.2%
Value $2.025M Shares 1,500,000 Share Price $1.35 Est. Cost/Share $0.99 Unrealized @ Report Date —
— NEW YORK CMNTY BANCORP INC 0.2%
Value $1.953M Shares 606,600 Share Price $3.22 Est. Cost/Share $9.04 Unrealized @ Report Date —
— ALIGOS THERAPEUTICS INC 0.2%
Value $1.617M Shares 1,650,000 Share Price $0.98 Est. Cost/Share $1.06 Unrealized @ Report Date —
— ENZO BIOCHEM INC 0.2%
Value $1.6M Shares 1,260,013 Share Price $1.27 Est. Cost/Share $2.43 Unrealized @ Report Date —
TGTX TG THERAPEUTICS INC 0.2%
Value $1.521M Shares 100,000 Share Price $15.21 * Est. Cost/Share $13.94 Unrealized @ Report Date +14.3%
— ATARA BIOTHERAPEUTICS INC 0.1%
Value $1.305M Shares 1,879,923 Share Price $0.69 Est. Cost/Share $0.69 Unrealized @ Report Date —
SEER SEER INC 0.1%
Value $1.281M Shares 674,125 Share Price $1.90 * Est. Cost/Share $1.80 Unrealized @ Report Date 0.0%
IFRX INFLARX NV 0.1%
Value $1.184M Shares 769,065 Share Price $1.54 * Est. Cost/Share $4.48 Unrealized @ Report Date -63.5%
— AVROBIO INC 0.1%
Value $1.092M Shares 852,802 Share Price $1.28 Est. Cost/Share $1.28 Unrealized @ Report Date —
ABOS ACUMEN PHARMACEUTICALS INC 0.1%
Value $1M Shares 246,895 Share Price $4.05 * Est. Cost/Share $2.97 Unrealized @ Report Date +27.0%
— REVANCE THERAPEUTICS INC 0.1%
Value $984K Shares 200,000 Share Price $4.92 Est. Cost/Share $4.92 Unrealized @ Report Date —
ATYR ATYR PHARMA INC 0.1%
Value $919K Shares 471,134 Share Price $1.95 * Est. Cost/Share $2.95 Unrealized @ Report Date -40.9%
— SERES THERAPEUTICS INC 0.1%
Value $702K Shares 907,112 Share Price $0.77 Est. Cost/Share $1.40 Unrealized @ Report Date —
QURE UNIQURE NV 0.1%
Value $696K Shares 133,921 Share Price $5.20 * Est. Cost/Share $9.00 Unrealized @ Report Date -36.3%
EGRX EAGLE PHARMACEUTICALS INC 0.1%
Value $623K Shares 118,857 Share Price $5.24 * Est. Cost/Share $32.45 Unrealized @ Report Date -83.1%
— KEZAR LIFE SCIENCES INC 0.1%
Value $621K Shares 688,943 Share Price $0.90 Est. Cost/Share $0.92 Unrealized @ Report Date —
DERM JOURNEY MED CORP 0.1%
Value $510K Shares 138,625 Share Price $3.68 * Est. Cost/Share $4.35 Unrealized @ Report Date 0.0%
MOLN MOLECULAR PARTNERS AG 0.0%
Value $420K Shares 100,000 Share Price $4.20 Est. Cost/Share $5.03 Unrealized @ Report Date —
— NEXTCURE INC 0.0%
Value $322K Shares 144,520 Share Price $2.23 Est. Cost/Share $1.43 Unrealized @ Report Date —
AMLX AMYLYX PHARMACEUTICALS INC 0.0%
Value $284K Shares 100,000 Share Price $2.84 * Est. Cost/Share $15.33 Unrealized @ Report Date -14.7%
ERAS ERASCA INC 0.0%
Value $206K Shares 100,000 Share Price $2.06 * Est. Cost/Share $2.11 Unrealized @ Report Date -5.2%
RLMD RELMADA THERAPEUTICS INC 0.0%
Value $1,776 Shares 382 Share Price $4.65 * Est. Cost/Share $4.82 Unrealized @ Report Date 0.0%