Location: San Diego, CA
CIK: 0001232621 · Show all filings
Period: Q2 2024 (← Previous) (Next →)
Filing Date: Aug 14, 2024
Total Value: $982M (99.7% shares, 0.3% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| TARS | TARSUS PHARMACEUTICALS INC | 2,254,797 | $61.29M | 6.2% | $16.20 | +107.5% | COM | 87650L103 |
| EOLS | EVOLUS INC | 4,847,399 | $52.59M | 5.4% | $10.18 | +20.8% | COM | 30052C107 |
| KALV | KALVISTA PHARMACEUTICALS INC | 4,218,829 | $49.7M | 5.1% | $10.13 | +15.2% | COM | 483497103 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,287,107 | $44.01M | 4.5% | $22.11 | +18.6% | COM | 604749101 |
| ANAB | ANAPTYSBIO INC | 1,330,879 | $33.35M | 3.4% | $21.51 | +8.3% | COM | 032724106 |
| ANIP | ANI PHARMACEUTICALS INC | 450,000 | $28.66M | 2.9% | $63.41 | +2.4% | COM | 00182C103 |
| — | DYNAVAX TECHNOLOGIES CORP | 2,500,000 | $28.07M | 2.9% | $11.23 | — | COM NEW | 268158201 |
| LLY | ELI LILLY & CO | 27,000 | $24.45M | 2.5% | $340.49 | +132.3% | COM | 532457108 |
| ACAD | ACADIA PHARMACEUTICALS INC | 1,500,000 | $24.38M | 2.5% | $19.28 | -16.3% | COM | 004225108 |
| PCVX | VAXCYTE INC | 300,000 | $22.65M | 2.3% | $39.24 | +73.5% | COM | 92243G108 |
| PTCT | PTC THERAPEUTICS INC | 700,000 | $21.41M | 2.2% | $22.87 | +41.7% | COM | 69366J200 |
| — | INTRA-CELLULAR THERAPIES INC | 300,000 | $20.55M | 2.1% | $64.14 | — | COM | 46116X101 |
| ALT | ALTIMMUNE INC | 2,750,000 | $18.29M | 1.9% | $9.59 | -23.1% | COM NEW | 02155H200 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 1,392,925 | $18.12M | 1.8% | $14.87 | -6.9% | COM | 92790C104 |
| — | AVADEL PHARMACEUTICALS PLC | 1,230,000 | $17.29M | 1.8% | $14.06 | — | COM SHS | G29687103 |
| CRSP | CRISPR THERAPEUTICS AG | 316,500 | $17.09M | 1.7% | $56.80 | +1.8% | NAMEN AKT | H17182108 |
| RCKT | ROCKET PHARMACEUTICALS INC | 750,000 | $16.15M | 1.6% | $24.86 | -7.6% | COM | 77313F106 |
| CGEM | CULLINAN THERAPEUTICS INC | 921,138 | $16.06M | 1.6% | $14.78 | +44.1% | COM | 230031106 |
| AUPH | AURINIA PHARMACEUTICALS INC | 2,779,500 | $15.87M | 1.6% | $7.00 | -24.8% | COM | 05156V102 |
| GSK | GSK PLC | 400,000 | $15.4M | 1.6% | $37.42 | — | SPONSORED ADR | 37733W204 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 140,000 | $14.94M | 1.5% | $109.94 | 0.0% | SHS USD | G50871105 |
| AVIR | ATEA PHARMACEUTICALS INC | 4,476,741 | $14.82M | 1.5% | $3.69 | +1.0% | COM | 04683R106 |
| NVDA | NVIDIA CORPORATION | 115,019 | $14.21M | 1.4% | $98.57 | +2.5% | COM | 67066G104 |
| IMCR | IMMUNOCORE HLDGS PLC | 405,600 | $13.75M | 1.4% | $30.74 | — | ADS | 45258D105 |
| LENZ | LENZ THERAPEUTICS INC | 747,616 | $12.93M | 1.3% | $19.90 | -12.2% | COM | 52635N103 |
| VNDA | VANDA PHARMACEUTICALS INC | 2,153,307 | $12.17M | 1.2% | $4.22 | +22.3% | COM | 921659108 |
| OTLK | OUTLOOK THERAPEUTICS INC | 1,619,412 | $11.95M | 1.2% | $8.09 | -0.7% | COM | 69012T305 |
| AZN | ASTRAZENECA PLC | 150,000 | $11.7M | 1.2% | $56.36 | — | SPONSORED ADR | 046353108 |
| KNSA | KINIKSA PHARMACEUTICALS INTL | 625,309 | $11.67M | 1.2% | $18.73 | 0.0% | ORD SHS CL A | G52694109 |
| NUVB | NUVATION BIO INC | 3,751,864 | $10.96M | 1.1% | $1.39 | +119.6% | COM CL A | 67080N101 |
| — | APPLIED THERAPEUTICS INC | 2,330,000 | $10.88M | 1.1% | $6.71 | — | COM | 03828A101 |
| — | ADICET BIO INC | 8,216,960 | $9.943M | 1.0% | $2.54 | — | COM | 007002108 |
| TDOC | TELADOC HEALTH INC | 1,000,000 | $9.78M | 1.0% | $12.20 | 0.0% | COM | 87918A105 |
| CTMX | CYTOMX THERAPEUTICS INC | 7,791,936 | $9.506M | 1.0% | $1.90 | +4.7% | COM | 23284F105 |
| — | CARGO THERAPEUTICS INC | 572,697 | $9.404M | 1.0% | $21.46 | — | COM | 14179K101 |
| ZYME | ZYMEWORKS INC | 1,100,000 | $9.361M | 1.0% | $8.10 | +9.8% | COM | 98985Y108 |
| IMNM | IMMUNOME INC | 720,000 | $8.712M | 0.9% | $20.29 | -22.9% | COM | 45257U108 |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | 281,200 | $8.484M | 0.9% | $41.26 | -27.1% | COM | 413197104 |
| — | ELEVATION ONCOLOGY INC | 3,060,000 | $8.262M | 0.8% | $1.54 | — | COM | 28623U101 |
| BIIB | BIOGEN INC | 35,000 | $8.114M | 0.8% | $217.32 | 0.0% | COM | 09062X103 |
| BDTX | BLACK DIAMOND THERAPEUTICS I | 1,603,200 | $7.471M | 0.8% | $2.64 | +103.1% | COM | 09203E105 |
| REPL | REPLIMUNE GROUP INC | 805,440 | $7.249M | 0.7% | $6.97 | 0.0% | COM | 76029N106 |
| VTYX | VENTYX BIOSCIENCES INC | 3,100,000 | $7.161M | 0.7% | $7.75 | -46.4% | COM | 92332V107 |
| IONS | IONIS PHARMACEUTICALS INC | 150,000 | $7.149M | 0.7% | $32.73 | +25.3% | COM | 462222100 |
| DNTH | DIANTHUS THERAPEUTICS INC | 264,692 | $6.85M | 0.7% | $12.62 | +90.5% | COM | 252828108 |
| INSM | INSMED INC | 100,000 | $6.7M | 0.7% | $38.78 | 0.0% | COM PAR $.01 | 457669307 |
| HRTX | HERON THERAPEUTICS INC | 1,850,000 | $6.475M | 0.7% | $4.36 | -29.5% | COM | 427746102 |
| VKTX | VIKING THERAPEUTICS INC | 120,000 | $6.361M | 0.6% | $48.00 | +36.5% | COM | 92686J106 |
| BEAM | BEAM THERAPEUTICS INC | 270,000 | $6.326M | 0.6% | $24.56 | 0.0% | COM | 07373V105 |
| DTIL | PRECISION BIOSCIENCES INC | 623,332 | $6.065M | 0.6% | $12.21 | -3.5% | COM NEW | 74019P207 |
| — | MERUS N V | 100,000 | $5.917M | 0.6% | $59.17 | — | COM | N5749R100 |
| META | META PLATFORMS INC | 11,396 | $5.746M | 0.6% | $448.12 | +7.9% | CL A | 30303M102 |
| GPCR | STRUCTURE THERAPEUTICS INC | 144,500 | $5.675M | 0.6% | $41.75 | — | SPONSORED ADS | 86366E106 |
| — | MARINUS PHARMACEUTICALS INC | 4,800,000 | $5.616M | 0.6% | $1.17 | — | COM NEW | 56854Q200 |
| CYTK | CYTOKINETICS INC | 100,000 | $5.418M | 0.6% | $36.21 | +66.7% | COM NEW | 23282W605 |
| ONC | BEIGENE LTD | 37,000 | $5.279M | 0.5% | $134.82 | — | SPONSORED ADR | 07725L102 |
| DSGN | DESIGN THERAPEUTICS INC | 1,480,975 | $4.961M | 0.5% | $4.45 | -12.5% | COM | 25056L103 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 800,000 | $4.944M | 0.5% | $9.70 | -43.1% | COM | 09058V103 |
| BHVN | BIOHAVEN LTD | 140,000 | $4.859M | 0.5% | $14.12 | +180.0% | COM | G1110E107 |
| ARVN | ARVINAS INC | 180,000 | $4.792M | 0.5% | $40.78 | -21.9% | COM | 04335A105 |
| ARE | ALEXANDRIA REAL ESTATE EQ IN | 40,000 | $4.679M | 0.5% | $108.07 | 0.0% | COM | 015271109 |
| — | RENEO PHARMACEUTICALS INC | 2,996,260 | $4.524M | 0.5% | $1.60 | — | COM | 75974E103 |
| LQDA | LIQUIDIA CORPORATION | 350,000 | $4.2M | 0.4% | $13.54 | -2.0% | COM NEW | 53635D202 |
| LNTH | LANTHEUS HLDGS INC | 50,000 | $4.014M | 0.4% | $58.85 | +24.7% | COM | 516544103 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 500,000 | $4.01M | 0.4% | $5.23 | +104.8% | COM | 462260100 |
| APGE | APOGEE THERAPEUTICS INC | 100,000 | $3.935M | 0.4% | $43.66 | +11.2% | COM | 03770N101 |
| ENTA | ENANTA PHARMACEUTICALS INC | 300,000 | $3.891M | 0.4% | $9.32 | +44.9% | COM | 29251M106 |
| SEER | SEER INC | 2,300,000 | $3.864M | 0.4% | $1.85 | +1.1% | COM CL A | 81578P106 |
| NKTX | NKARTA INC | 550,000 | $3.251M | 0.3% | $11.10 | -36.3% | COM | 65487U108 |
| — | BOLT BIOTHERAPEUTICS INC | 3,812,773 | $2.86M | 0.3% | $1.28 | — | COM | 097702104 |
| — | MIRUM PHARMACEUTICALS INC | 2,120,000 | $2.832M | 0.3% | $1.34 | — | NOTE 4.000% 5/0 | 604749AB7 |
| — | ATHIRA PHARMA INC | 1,052,715 | $2.79M | 0.3% | $2.66 | — | COM | 04746L104 |
| GMAB | GENMAB A/S | 100,000 | $2.513M | 0.3% | $29.91 | — | SPONSORED ADS | 372303206 |
| INBX | INHIBRX BIOSCIENCES INC | 167,500 | $2.373M | 0.2% | $15.62 | 0.0% | COM | 45720N103 |
| FATE | FATE THERAPEUTICS INC | 700,000 | $2.296M | 0.2% | $6.03 | -27.4% | COM | 31189P102 |
| IPSC | CENTURY THERAPEUTICS INC | 900,000 | $2.295M | 0.2% | $1.82 | +73.5% | COM | 15673T100 |
| DEI | DOUGLAS EMMETT INC | 171,138 | $2.278M | 0.2% | $13.31 | — | COM | 25960P109 |
| KURA | KURA ONCOLOGY INC | 100,000 | $2.059M | 0.2% | $19.44 | +5.7% | COM | 50127T109 |
| BCAB | BIOATLA INC | 1,374,076 | $1.882M | 0.2% | $6.46 | -63.2% | COM | 09077B104 |
| CHRS | COHERUS BIOSCIENCES INC | 1,050,000 | $1.817M | 0.2% | $2.01 | 0.0% | COM | 19249H103 |
| TGTX | TG THERAPEUTICS INC | 100,000 | $1.779M | 0.2% | $13.94 | +14.5% | COM | 88322Q108 |
| — | SERES THERAPEUTICS INC | 2,407,112 | $1.742M | 0.2% | $0.98 | — | COM | 81750R102 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 1,743,619 | $1.7M | 0.2% | $0.93 | — | SPONDS ADR | 00653A107 |
| VSTM | VERASTEM INC | 541,514 | $1.614M | 0.2% | $6.94 | +18.8% | COM NEW | 92337C203 |
| GLPG | GALAPAGOS NV | 55,609 | $1.378M | 0.1% | $24.78 | — | SPON ADR | 36315X101 |
| ABCL | ABCELLERA BIOLOGICS INC | 461,699 | $1.367M | 0.1% | $3.78 | 0.0% | COM | 00288U106 |
| TECX | TECTONIC THERAPEUTIC INC | 79,166 | $1.304M | 0.1% | $15.77 | 0.0% | COM | 878972108 |
| ERAS | ERASCA INC | 550,000 | $1.298M | 0.1% | $2.15 | +0.4% | COM | 29479A108 |
| — | PASSAGE BIO INC | 1,500,000 | $1.191M | 0.1% | $0.99 | — | COM | 702712100 |
| QNCX | QUINCE THERAPEUTICS INC | 1,500,000 | $1.125M | 0.1% | $0.98 | -7.7% | COM | 22053A107 |
| OABI | OMNIAB INC | 300,000 | $1.125M | 0.1% | $4.56 | 0.0% | COM | 68218J103 |
| ATYR | ATYR PHARMA INC | 671,134 | $1.047M | 0.1% | $2.59 | -32.8% | COM NEW | 002120202 |
| — | REVANCE THERAPEUTICS INC | 400,000 | $1.028M | 0.1% | $3.75 | — | COM | 761330109 |
| — | NEXTCURE INC | 602,994 | $959K | 0.1% | $1.55 | — | COM | 65343E108 |
| MGNX | MACROGENICS INC | 218,856 | $930K | 0.1% | $9.74 | 0.0% | COM | 556099109 |
| CCCC | C4 THERAPEUTICS INC | 200,000 | $924K | 0.1% | $5.96 | 0.0% | COM STK | 12529R107 |
| — | ASTRIA THERAPEUTICS INC | 100,000 | $910K | 0.1% | $9.10 | — | COM | 04635X102 |
| DERM | JOURNEY MED CORP | 148,322 | $837K | 0.1% | $4.34 | -5.1% | COM | 48115J109 |
| RLMD | RELMADA THERAPEUTICS INC | 237,874 | $714K | 0.1% | $3.62 | -0.1% | COM | 75955J402 |
| TYRA | TYRA BIOSCIENCES INC | 42,223 | $675K | 0.1% | $17.21 | 0.0% | COM | 90240B106 |
| EGRX | EAGLE PHARMACEUTICALS INC | 118,857 | $666K | 0.1% | $32.45 | -86.6% | COM | 269796108 |
| PBYI | PUMA BIOTECHNOLOGY INC | 200,000 | $652K | 0.1% | $4.39 | 0.0% | COM | 74587V107 |
| ATRA | ATARA BIOTHERAPEUTICS INC | 75,196 | $639K | 0.1% | $15.04 | 0.0% | COM NEW | 046513206 |
| — | ALIGOS THERAPEUTICS INC | 1,650,000 | $578K | 0.1% | $1.06 | — | COM | 01626L105 |
| JPM | JPMORGAN CHASE & CO. | 1,811 | $366K | 0.0% | $189.18 | 0.0% | COM | 46625H100 |
| MSFT | MICROSOFT CORP | 814 | $364K | 0.0% | $417.26 | 0.0% | COM | 594918104 |
| WMT | WALMART INC | 4,460 | $302K | 0.0% | $61.97 | 0.0% | COM | 931142103 |
| BRK/B | BERKSHIRE HATHAWAY INC DEL | 711 | $289K | 0.0% | $408.62 | 0.0% | CL B NEW | 084670702 |
| NFLX | NETFLIX INC | 427 | $288K | 0.0% | $62.46 | 0.0% | COM | 64110L106 |
| V | VISA INC | 1,049 | $275K | 0.0% | $270.83 | 0.0% | COM CL A | 92826C839 |
| PG | PROCTER AND GAMBLE CO | 1,543 | $254K | 0.0% | $157.20 | 0.0% | COM | 742718109 |
| VTRS | VIATRIS INC | 22,080 | $235K | 0.0% | $10.24 | 0.0% | COM | 92556V106 |
| TXN | TEXAS INSTRS INC | 1,204 | $234K | 0.0% | $176.15 | 0.0% | COM | 882508104 |
| HD | HOME DEPOT INC | 679 | $234K | 0.0% | $327.56 | 0.0% | COM | 437076102 |
| AXP | AMERICAN EXPRESS CO | 1,001 | $232K | 0.0% | $227.31 | 0.0% | COM | 025816109 |
| INTC | INTEL CORP | 7,354 | $228K | 0.0% | $32.50 | 0.0% | COM | 458140100 |
| KO | COCA COLA CO | 3,561 | $227K | 0.0% | $58.89 | 0.0% | COM | 191216100 |
| AMZN | AMAZON COM INC | 1,164 | $225K | 0.0% | $183.70 | 0.0% | COM | 023135106 |
| IVVD | INVIVYD INC | 200,000 | $220K | 0.0% | $2.21 | 0.0% | COM | 00534A102 |
| GE | GE AEROSPACE | 1,383 | $220K | 0.0% | $157.95 | 0.0% | COM NEW | 369604301 |
| XOM | EXXON MOBIL CORP | 1,908 | $220K | 0.0% | $110.09 | 0.0% | COM | 30231G102 |
| VZ | VERIZON COMMUNICATIONS INC | 5,308 | $219K | 0.0% | $36.47 | 0.0% | COM | 92343V104 |
| DIS | DISNEY WALT CO | 2,029 | $201K | 0.0% | $105.51 | 0.0% | COM | 254687106 |
| ALL | ALLSTATE CORP | 1,260 | $201K | 0.0% | $161.46 | 0.0% | COM | 020002101 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 100,000 | $190K | 0.0% | $15.33 | -87.4% | COM | 03237H101 |
| F | FORD MTR CO DEL | 12,773 | $160K | 0.0% | $11.13 | 0.0% | COM | 345370860 |
| MOLN | MOLECULAR PARTNERS AG | 2,500 | $18,075 | 0.0% | $5.03 | — | ADS | 60853G106 |
| — | LAVA THERAPEUTICS NV | 5,109 | $9,196 | 0.0% | $1.80 | — | SHS | N51517105 |