Location: San Diego, CA
CIK: 0001232621 · Show all filings
Period: Q4 2025 (← Previous) (Next →)
Filing Date: Feb 17, 2026
Total Value: $2.024B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| AUPH | AURINIA PHARMACEUTICALS INC | 11,329,500 | $181M | 8.9% | $15.95 * | $7.41 | +91.2% | COM | 05156V102 |
| GLPG | GALAPAGOS NV | 3,921,219 | $128M | 6.3% | $32.70 | $26.90 | — | SPON ADR | 36315X101 |
| PTCT | PTC THERAPEUTICS INC | 1,500,000 | $114M | 5.6% | $75.96 * | $37.71 | +92.7% | COM | 69366J200 |
| CELC | CELCUITY INC | 1,050,000 | $105M | 5.2% | $99.74 * | $40.03 | +105.4% | COM | 15102K100 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,236,027 | $97.63M | 4.8% | $78.99 * | $22.11 | +224.6% | COM | 604749101 |
| TARS | TARSUS PHARMACEUTICALS INC | 1,188,624 | $97.32M | 4.8% | $81.88 * | $18.91 | +294.9% | COM | 87650L103 |
| KNSA | KINIKSA PHARMACEUTICALS INTL | 2,259,889 | $93.22M | 4.6% | $41.25 * | $20.52 | +95.5% | ORD SHS CL A | G52694109 |
| IMCR | IMMUNOCORE HLDGS PLC | 2,628,538 | $91.24M | 4.5% | $34.71 | $31.44 | — | ADS | 45258D105 |
| CMPX | COMPASS THERAPEUTICS INC | 16,790,809 | $90.17M | 4.5% | $5.37 * | $2.28 | +102.9% | COM | 20454B104 |
| KALV | KALVISTA PHARMACEUTICALS INC | 4,573,530 | $73.86M | 3.6% | $16.15 * | $10.28 | +28.8% | COM | 483497103 |
| RNAM | AVIDITY BIOSCIENCES INC | 900,000 | $64.92M | 3.2% | $72.13 * | $64.59 | 0.0% | COM | 05370A108 |
| ANAB | ANAPTYSBIO INC | 1,332,087 | $64.58M | 3.2% | $48.48 * | $20.84 | +87.1% | COM | 032724106 |
| SYRE | SPYRE THERAPEUTICS INC | 1,892,200 | $61.99M | 3.1% | $32.76 * | $18.65 | +40.1% | COM NEW | 00773J202 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 1,792,626 | $55.79M | 2.8% | $31.12 * | $16.12 | +70.1% | COM | 92790C104 |
| CAPR | CAPRICOR THERAPEUTICS INC | 1,700,000 | $49.06M | 2.4% | $28.86 * | $13.06 | 0.0% | COM NEW | 14070B309 |
| BNTX | BIONTECH SE | 470,000 | $44.74M | 2.2% | $95.20 | $108.74 | — | SPONSORED ADS | 09075V102 |
| ANIP | ANI PHARMACEUTICALS INC | 481,437 | $38M | 1.9% | $78.94 * | $71.30 | +21.4% | COM | 00182C103 |
| VRTX | VERTEX PHARMACEUTICALS INC | 80,000 | $36.27M | 1.8% | $453.36 * | $423.29 | +1.8% | COM | 92532F100 |
| NUVB | NUVATION BIO INC | 3,857,457 | $34.56M | 1.7% | $8.96 * | $1.54 | +301.3% | COM CL A | 67080N101 |
| TVTX | TRAVERE THERAPEUTICS INC | 700,000 | $26.75M | 1.3% | $38.21 * | $16.57 | +96.2% | COM | 89422G107 |
| VTYX | VENTYX BIOSCIENCES INC | 2,814,000 | $25.41M | 1.3% | $9.03 * | $7.75 | -3.6% | COM | 92332V107 |
| NVDA | NVIDIA CORPORATION | 127,788 | $23.83M | 1.2% | $186.50 | $102.89 | +80.9% | COM | 67066G104 |
| PGEN | PRECIGEN INC | 5,617,500 | $23.48M | 1.2% | $4.18 * | $2.82 | +37.0% | COM | 74017N105 |
| SPY | SPDR S&P 500 ETF TR | 30,000 | $20.46M | 1.0% | $681.92 | $681.92 | — | TR UNIT | 78462F103 |
| MRNA | MODERNA INC | 692,820 | $20.43M | 1.0% | $29.49 * | $36.16 | -24.9% | COM | 60770K107 |
| VKTX | VIKING THERAPEUTICS INC | 500,000 | $17.59M | 0.9% | $35.18 | $36.82 | -3.8% | COM | 92686J106 |
| AVIR | ATEA PHARMACEUTICALS INC | 4,814,700 | $17.19M | 0.8% | $3.57 * | $3.66 | -13.3% | COM | 04683R106 |
| STOK | STOKE THERAPEUTICS INC | 500,000 | $15.87M | 0.8% | $31.74 * | $11.10 | +170.8% | COM | 86150R107 |
| IDYA | IDEAYA BIOSCIENCES INC | 450,000 | $15.56M | 0.8% | $34.57 * | $25.04 | +27.3% | COM | 45166A102 |
| META | META PLATFORMS INC | 23,331 | $15.4M | 0.8% | $660.09 | $492.27 | +35.6% | CL A | 30303M102 |
| GSK | GSK PLC | 300,000 | $14.71M | 0.7% | $49.04 | $37.80 | — | SPONSORED ADR | 37733W204 |
| DERM | JOURNEY MED CORP | 1,854,596 | $14.3M | 0.7% | $7.71 | $5.43 | +44.5% | COM | 48115J109 |
| LENZ | LENZ THERAPEUTICS INC | 865,169 | $13.84M | 0.7% | $16.00 * | $21.01 | +38.7% | COM | 52635N103 |
| PCVX | VAXCYTE INC | 275,000 | $12.69M | 0.6% | $46.14 * | $39.24 | +14.0% | COM | 92243G108 |
| DNTH | DIANTHUS THERAPEUTICS INC | 264,692 | $10.91M | 0.5% | $41.21 * | $12.62 | +207.3% | COM | 252828108 |
| HRMY | HARMONY BIOSCIENCES HLDGS IN | 290,292 | $10.86M | 0.5% | $37.42 * | $41.00 | -19.8% | COM | 413197104 |
| BMY | BRISTOL-MYERS SQUIBB CO | 200,000 | $10.79M | 0.5% | $53.94 * | $47.53 | 0.0% | COM | 110122108 |
| INSM | INSMED INC | 60,000 | $10.44M | 0.5% | $174.04 * | $57.62 | +216.7% | COM PAR $.01 | 457669307 |
| CBIO | CRESCENT BIOPHARMA INC. | 872,398 | $10.35M | 0.5% | $11.86 * | $13.60 | -6.3% | COM | G2545C104 |
| WVE | WAVE LIFE SCIENCES LTD | 600,000 | $10.2M | 0.5% | $17.00 * | $10.16 | 0.0% | SHS | Y95308105 |
| TDOC | TELADOC HEALTH INC | 1,400,000 | $9.8M | 0.5% | $7.00 * | $11.08 | -29.3% | COM | 87918A105 |
| — | DYNAVAX TECHNOLOGIES CORP | 556,359 | $8.557M | 0.4% | $15.38 | $12.41 | — | COM NEW | 268158201 |
| EOLS | EVOLUS INC | 1,245,692 | $8.284M | 0.4% | $6.65 | $10.07 | -32.7% | COM | 30052C107 |
| VSTM | VERASTEM INC | 1,069,810 | $8.259M | 0.4% | $7.72 * | $7.70 | +15.7% | COM NEW | 92337C203 |
| URGN | UROGEN PHARMA LTD | 350,000 | $8.197M | 0.4% | $23.42 * | $9.60 | +126.1% | COM | M96088105 |
| HRTX | HERON THERAPEUTICS INC | 6,250,000 | $8.125M | 0.4% | $1.30 * | $2.22 | -44.3% | COM | 427746102 |
| ACAD | ACADIA PHARMACEUTICALS INC | 300,000 | $8.013M | 0.4% | $26.71 * | $19.28 | +24.0% | COM | 004225108 |
| ALT | ALTIMMUNE INC | 2,131,307 | $7.694M | 0.4% | $3.61 * | $9.59 | -54.5% | COM NEW | 02155H200 |
| SRPT | SAREPTA THERAPEUTICS INC | 349,220 | $7.515M | 0.4% | $21.52 * | $35.22 | -40.2% | COM | 803607100 |
| PLRX | PLIANT THERAPEUTICS INC | 6,143,132 | $7.495M | 0.4% | $1.22 * | $5.97 | -74.8% | COM | 729139105 |
| ARVN | ARVINAS INC | 569,698 | $6.757M | 0.3% | $11.86 * | $15.67 | -30.3% | COM | 04335A105 |
| TBPH | THERAVANCE BIOPHARMA INC | 351,252 | $6.572M | 0.3% | $18.71 * | $10.62 | +56.1% | COM | G8807B106 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 800,000 | $6.24M | 0.3% | $7.80 * | $9.70 | -25.5% | COM | 09058V103 |
| PMVP | PMV PHARMACEUTICALS INC | 4,940,000 | $6.175M | 0.3% | $1.25 * | $1.38 | -3.1% | COM | 69353Y103 |
| REGN | REGENERON PHARMACEUTICALS | 8,000 | $6.175M | 0.3% | $771.87 * | $714.47 | -5.0% | COM | 75886F107 |
| BIIB | BIOGEN INC | 35,000 | $6.16M | 0.3% | $175.99 * | $217.32 | -24.8% | COM | 09062X103 |
| CORT | CORCEPT THERAPEUTICS INC | 156,764 | $5.455M | 0.3% | $34.80 * | $78.55 | 0.0% | COM | 218352102 |
| ABEO | ABEONA THERAPEUTICS INC | 1,000,000 | $5.27M | 0.3% | $5.27 * | $5.03 | 0.0% | COM NEW | 00289Y206 |
| IBRX | IMMUNITYBIO INC | 2,333,333 | $4.62M | 0.2% | $1.98 * | $4.17 | -45.6% | COM | 45256X103 |
| KZR | KEZAR LIFE SCIENCES INC | 664,314 | $4.179M | 0.2% | $6.29 * | $7.45 | -21.7% | COM NEW | 49372L209 |
| CHRS | COHERUS ONCOLOGY INC | 2,724,509 | $3.869M | 0.2% | $1.42 | $1.38 | +5.8% | COM | 19249H103 |
| ERAS | ERASCA INC | 900,000 | $3.348M | 0.2% | $3.72 * | $1.85 | +52.0% | COM | 29479A108 |
| NKTX | NKARTA INC | 1,480,823 | $2.74M | 0.1% | $1.85 * | $3.05 | -34.4% | COM | 65487U108 |
| NUVL | NUVALENT INC | 21,880 | $2.201M | 0.1% | $100.59 | $82.95 | +18.9% | COM | 670703107 |
| ARE | ALEXANDRIA REAL ESTATE EQ IN | 40,000 | $1.958M | 0.1% | $48.94 * | $108.07 | -46.3% | COM | 015271109 |
| NMRA | NEUMORA THERAPEUTICS INC. | 967,235 | $1.731M | 0.1% | $1.79 * | $1.71 | +27.9% | COM | 640979100 |
| STRO | SUTRO BIOPHARMA INC | 139,617 | $1.615M | 0.1% | $11.57 * | $9.49 | 0.0% | COM SHS | 869367201 |
| BHVN | BIOHAVEN LTD | 140,000 | $1.581M | 0.1% | $11.29 * | $14.12 | -12.3% | COM | G1110E107 |
| RVMD | REVOLUTION MEDICINES INC | 15,640 | $1.246M | 0.1% | $79.65 * | $50.47 | +29.9% | COM | 76155X100 |
| FATE | FATE THERAPEUTICS INC | 1,167,773 | $1.147M | 0.1% | $0.98 * | $3.85 | -68.8% | COM | 31189P102 |
| ZYME | ZYMEWORKS INC | 34,631 | $912K | 0.0% | $26.33 * | $8.10 | +169.1% | COM | 98985Y108 |
| RCKT | ROCKET PHARMACEUTICALS INC | 100,000 | $351K | 0.0% | $3.51 * | $23.10 | -85.2% | COM | 77313F106 |
| ACET | ADICET BIO INC | 6,158 | $51,850 | 0.0% | $8.42 * | $11.05 | 0.0% | COM NEW | 007002207 |
| TCRX | TSCAN THERAPEUTICS INC | 46,131 | $46,131 | 0.0% | $1.00 * | $2.63 | -44.9% | COM | 89854M101 |
| SAVA | CASSAVA SCIENCES INC | 7,073 | $14,005 | 0.0% | $1.98 * | $2.40 | +33.4% | COM | 14817C107 |