Palo Alto Investors LP Long-Term Concentrated

Location: Palo Alto, CA

CIK: 0001306923 · Show all filings

Period: Q3 2020 (← Previous) (Next →)

Filing Date: Nov 16, 2020

Total Value: $1.822B (100.0% shares, 0.0% debt)

Holdings (43)

— IMMUNOMEDICS INC 22.6%
Value $413M Shares 4,852,383 Share Price $85.03 Est. Cost/Share $13.38 Unrealized @ Report Date —
INSM INSMED INC 10.6%
Value $194M Shares 6,032,956 Share Price $32.14 * Est. Cost/Share $17.16 Unrealized @ Report Date +67.5%
STAA STAAR SURGICAL CO 8.7%
Value $158M Shares 2,791,693 Share Price $56.56 * Est. Cost/Share $13.06 Unrealized @ Report Date +312.4%
— ABIOMED INC 7.7%
Value $140M Shares 504,033 Share Price $277.06 Est. Cost/Share $43.36 Unrealized @ Report Date —
BMRN BIOMARIN PHARMACEUTICAL INC 7.2%
Value $132M Shares 1,732,550 Share Price $76.08 * Est. Cost/Share $84.14 Unrealized @ Report Date +20.2%
FOLD AMICUS THERAPEUTICS INC 6.1%
Value $111M Shares 7,867,114 Share Price $14.12 * Est. Cost/Share $8.07 Unrealized @ Report Date +80.7%
UTHR UNITED THERAPEUTICS CORP 4.4%
Value $79.33M Shares 785,406 Share Price $101.00 * Est. Cost/Share $89.23 Unrealized @ Report Date +23.0%
— EPIZYME INC 4.2%
Value $76.39M Shares 6,403,600 Share Price $11.93 Est. Cost/Share $14.68 Unrealized @ Report Date —
ACAD ACADIA PHARMACEUTICALS INC 4.1%
Value $75.58M Shares 1,832,300 Share Price $41.25 * Est. Cost/Share $29.66 Unrealized @ Report Date +45.6%
— KARYOPHARM THERAPEUTICS INC 4.1%
Value $74.26M Shares 5,086,152 Share Price $14.60 Est. Cost/Share $16.94 Unrealized @ Report Date —
— ALEXION PHARMACEUTICALS INC 2.9%
Value $52.35M Shares 457,529 Share Price $114.43 Est. Cost/Share $121.34 Unrealized @ Report Date —
— REVANCE THERAPEUTICS INC 2.8%
Value $50.15M Shares 1,994,905 Share Price $25.14 Est. Cost/Share $21.62 Unrealized @ Report Date —
VNDA VANDA PHARMACEUTICALS INC 2.2%
Value $40.28M Shares 4,170,281 Share Price $9.66 * Est. Cost/Share $11.20 Unrealized @ Report Date -4.6%
— SAGE THERAPEUTICS INC 2.0%
Value $36.07M Shares 590,200 Share Price $61.12 Est. Cost/Share $48.94 Unrealized @ Report Date —
— AMAG PHARMACEUTICALS INC 1.5%
Value $28.24M Shares 3,003,875 Share Price $9.40 Est. Cost/Share $28.78 Unrealized @ Report Date —
— CLOVIS ONCOLOGY INC 1.4%
Value $26.06M Shares 4,469,411 Share Price $5.83 Est. Cost/Share $47.56 Unrealized @ Report Date —
EHTH EHEALTH INC 1.2%
Value $22.16M Shares 280,438 Share Price $79.00 * Est. Cost/Share $81.05 Unrealized @ Report Date 0.0%
ALGN ALIGN TECHNOLOGY INC 1.2%
Value $22.1M Shares 67,505 Share Price $327.35 * Est. Cost/Share $114.31 Unrealized @ Report Date +167.0%
PBYI PUMA BIOTECHNOLOGY INC 0.8%
Value $13.81M Shares 1,368,317 Share Price $10.09 Est. Cost/Share $27.93 Unrealized @ Report Date -63.5%
GOSS GOSSAMER BIO INC 0.7%
Value $13.37M Shares 1,077,200 Share Price $12.41 * Est. Cost/Share $13.13 Unrealized @ Report Date +1.0%
PRTA PROTHENA CORP PLC 0.7%
Value $13.27M Shares 1,328,734 Share Price $9.99 * Est. Cost/Share $24.19 Unrealized @ Report Date -50.3%
KLDO KALEIDO BIOSCIENCES INC 0.5%
Value $8.705M Shares 786,400 Share Price $11.07 * Est. Cost/Share $13.76 Unrealized @ Report Date -49.7%
— DICERNA PHARMACEUTICALS INC 0.3%
Value $5.969M Shares 331,813 Share Price $17.99 Est. Cost/Share $5.39 Unrealized @ Report Date —
ANAB ANAPTYSBIO INC 0.3%
Value $5.439M Shares 368,722 Share Price $14.75 * Est. Cost/Share $18.04 Unrealized @ Report Date 0.0%
— ATHENEX INC 0.2%
Value $3.107M Shares 256,800 Share Price $12.10 Est. Cost/Share $13.30 Unrealized @ Report Date —
— ZOGENIX INC 0.2%
Value $2.933M Shares 163,600 Share Price $17.93 Est. Cost/Share $21.25 Unrealized @ Report Date —
SNDX SYNDAX PHARMACEUTICALS INC 0.2%
Value $2.928M Shares 198,400 Share Price $14.76 * Est. Cost/Share $13.29 Unrealized @ Report Date +14.7%
— RETROPHIN INC 0.2%
Value $2.915M Shares 157,900 Share Price $18.46 Est. Cost/Share $17.31 Unrealized @ Report Date —
— APREA THERAPEUTICS INC 0.2%
Value $2.882M Shares 119,800 Share Price $24.06 Est. Cost/Share $29.86 Unrealized @ Report Date —
— RIGEL PHARMACEUTICALS INC 0.2%
Value $2.842M Shares 1,184,092 Share Price $2.40 Est. Cost/Share $3.40 Unrealized @ Report Date —
CYTK CYTOKINETICS INC 0.1%
Value $2.678M Shares 123,686 Share Price $21.65 * Est. Cost/Share $6.71 Unrealized @ Report Date +248.4%
— KEZAR LIFE SCIENCES INC 0.1%
Value $2.368M Shares 489,319 Share Price $4.84 Est. Cost/Share $4.98 Unrealized @ Report Date —
— MAGENTA THERAPEUTICS INC 0.1%
Value $2.337M Shares 343,700 Share Price $6.80 Est. Cost/Share $7.20 Unrealized @ Report Date —
— TRICIDA INC 0.1%
Value $1.547M Shares 170,800 Share Price $9.06 Est. Cost/Share $9.06 Unrealized @ Report Date —
EOLS EVOLUS INC 0.1%
Value $1.039M Shares 265,700 Share Price $3.91 * Est. Cost/Share $3.65 Unrealized @ Report Date 0.0%
— ALIMERA SCIENCES INC 0.1%
Value $976K Shares 200,919 Share Price $4.86 Est. Cost/Share $6.30 Unrealized @ Report Date —
ALDX ALDEYRA THERAPEUTICS INC 0.0%
Value $874K Shares 118,000 Share Price $7.41 * Est. Cost/Share $7.12 Unrealized @ Report Date -9.3%
— AIMMUNE THERAPEUTICS INC 0.0%
Value $682K Shares 19,800 Share Price $34.44 Est. Cost/Share $22.84 Unrealized @ Report Date —
URGN UROGEN PHARMA LTD 0.0%
Value $473K Shares 24,500 Share Price $19.31 * Est. Cost/Share $27.01 Unrealized @ Report Date -16.2%
— MARINUS PHARMACEUTICALS INC 0.0%
Value $403K Shares 31,330 Share Price $12.86 Est. Cost/Share $4.17 Unrealized @ Report Date —
— IDERA PHARMACEUTICALS INC 0.0%
Value $165K Shares 77,044 Share Price $2.14 Est. Cost/Share $8.90 Unrealized @ Report Date —
— SUNESIS PHARMACEUTICALS INC 0.0%
Value $145K Shares 116,246 Share Price $1.25 Est. Cost/Share $4.37 Unrealized @ Report Date —
— MINERVA NEUROSCIENCES INC 0.0%
Value $115K Shares 36,319 Share Price $3.17 Est. Cost/Share $5.62 Unrealized @ Report Date —