Location: Palo Alto, CA
CIK: 0001306923 · Show all filings
Period: Q4 2020 (← Previous) (Next →)
Filing Date: Feb 16, 2021
Total Value: $1.908B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| STAA | STAAR SURGICAL CO | 2,849,348 | $226M | 11.8% | $79.22 * | $14.28 | +412.6% | COM PAR $0.01 | 852312305 |
| INSM | INSMED INC | 6,105,980 | $203M | 10.7% | $33.29 * | $17.39 | +110.0% | COM PAR $.01 | 457669307 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 2,155,050 | $189M | 9.9% | $87.69 * | $83.19 | -4.7% | COM | 09061G101 |
| FOLD | AMICUS THERAPEUTICS INC | 7,867,114 | $182M | 9.5% | $23.09 * | $8.07 | +153.5% | COM | 03152W109 |
| — | ABIOMED INC | 556,633 | $180M | 9.5% | $324.20 | $69.89 | — | COM | 003654100 |
| ACAD | ACADIA PHARMACEUTICALS INC | 2,301,477 | $123M | 6.4% | $53.46 * | $33.73 | +47.2% | COM | 004225108 |
| UTHR | UNITED THERAPEUTICS CORP | 785,406 | $119M | 6.2% | $151.79 * | $89.23 | +47.1% | COM | 91307C102 |
| — | KARYOPHARM THERAPEUTICS INC | 5,267,652 | $81.54M | 4.3% | $15.48 | $16.89 | — | COM | 48576U106 |
| — | ALEXION PHARMACEUTICALS INC | 503,429 | $78.66M | 4.1% | $156.24 | $124.52 | — | COM | 015351109 |
| — | REVANCE THERAPEUTICS INC | 2,673,313 | $75.76M | 4.0% | $28.34 | $23.32 | — | COM | 761330109 |
| — | EPIZYME INC | 6,738,913 | $73.19M | 3.8% | $10.86 | $14.49 | — | COM | 29428V104 |
| BIIB | BIOGEN INC | 234,300 | $57.37M | 3.0% | $244.86 * | $259.08 | 0.0% | COM | 09062X103 |
| VNDA | VANDA PHARMACEUTICALS INC | 4,230,548 | $55.59M | 2.9% | $13.14 * | $11.21 | +7.3% | COM | 921659108 |
| — | SAGE THERAPEUTICS INC | 590,200 | $51.06M | 2.7% | $86.51 | $48.94 | — | COM | 78667J108 |
| EHTH | EHEALTH INC | 586,999 | $41.45M | 2.2% | $70.61 * | $78.41 | -3.1% | COM | 28238P109 |
| ALGN | ALIGN TECHNOLOGY INC | 67,505 | $36.07M | 1.9% | $534.38 * | $114.31 | +293.3% | COM | 016255101 |
| — | CLOVIS ONCOLOGY INC | 4,469,411 | $21.45M | 1.1% | $4.80 | $47.56 | — | COM | 189464100 |
| PRTA | PROTHENA CORP PLC | 1,691,805 | $20.32M | 1.1% | $12.01 | $21.54 | -45.1% | SHS | G72800108 |
| GOSS | GOSSAMER BIO INC | 1,739,050 | $16.82M | 0.9% | $9.67 | $11.88 | -17.1% | COM | 38341P102 |
| PBYI | PUMA BIOTECHNOLOGY INC | 1,373,897 | $14.1M | 0.7% | $10.26 | $27.93 | -63.8% | COM | 74587V107 |
| ANAB | ANAPTYSBIO INC | 416,292 | $8.95M | 0.5% | $21.50 * | $18.75 | +29.5% | COM | 032724106 |
| — | DICERNA PHARMACEUTICALS INC | 331,813 | $7.31M | 0.4% | $22.03 | $5.39 | — | COM | 253031108 |
| KLDO | KALEIDO BIOSCIENCES INC | 786,400 | $7.156M | 0.4% | $9.10 * | $13.76 | -40.4% | COM | 483347100 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 264,200 | $5.876M | 0.3% | $22.24 * | $15.14 | +37.0% | COM | 87164F105 |
| TVTX | TRAVERE THERAPEUTICS INC | 157,900 | $4.304M | 0.2% | $27.26 * | $23.35 | 0.0% | COM | 89422G107 |
| — | ZOGENIX INC | 214,700 | $4.292M | 0.2% | $19.99 | $20.95 | — | COM NEW | 98978L204 |
| — | ATHENEX INC | 318,200 | $3.519M | 0.2% | $11.06 | $12.86 | — | COM | 04685N103 |
| — | RIGEL PHARMACEUTICALS INC | 998,156 | $3.494M | 0.2% | $3.50 | $3.40 | — | COM NEW | 766559603 |
| — | MAGENTA THERAPEUTICS INC | 427,108 | $3.349M | 0.2% | $7.84 | $7.33 | — | COM | 55910K108 |
| ALKS | ALKERMES PLC | 150,598 | $3.004M | 0.2% | $19.95 * | $18.28 | 0.0% | SHS | G01767105 |
| — | KEZAR LIFE SCIENCES INC | 548,206 | $2.862M | 0.2% | $5.22 | $5.01 | — | COM | 49372L100 |
| CYTK | CYTOKINETICS INC | 123,686 | $2.57M | 0.1% | $20.78 * | $6.71 | +172.2% | COM NEW | 23282W605 |
| TCMD | TACTILE SYSTEMS TECHNOLOGY I | 27,100 | $1.218M | 0.1% | $44.94 * | $39.74 | 0.0% | COM | 87357P100 |
| ALDX | ALDEYRA THERAPEUTICS INC | 160,800 | $1.103M | 0.1% | $6.86 * | $7.10 | -1.1% | COM | 01438T106 |
| — | ALIMERA SCIENCES INC | 200,919 | $848K | 0.0% | $4.22 | $6.30 | — | COM NEW | 016259202 |
| — | APREA THERAPEUTICS INC | 128,770 | $634K | 0.0% | $4.92 | $28.13 | — | COM | 03836J102 |
| URGN | UROGEN PHARMA LTD | 24,500 | $441K | 0.0% | $18.00 * | $27.01 | -22.4% | COM | M96088105 |
| — | MARINUS PHARMACEUTICALS INC | 31,330 | $382K | 0.0% | $12.19 | $4.17 | — | COM | 56854Q101 |
| — | IDERA PHARMACEUTICALS INC | 77,044 | $283K | 0.0% | $3.67 | $8.90 | — | COM PAR | 45168K405 |
| — | SUNESIS PHARMACEUTICALS INC | 116,246 | $231K | 0.0% | $1.99 | $4.37 | — | COM | 867328700 |
| — | MINERVA NEUROSCIENCES INC | 36,319 | $85,000 | 0.0% | $2.34 | $5.62 | — | COM | 603380106 |