Location: Palo Alto, CA
CIK: 0001306923 · Show all filings
Period: Q3 2024 (← Previous) (Next →)
Filing Date: Nov 14, 2024
Total Value: $770M (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| INSM | INSMED INC | 1,940,993 | $142M | 18.4% | $73.00 | $17.79 | +314.8% | COM PAR $.01 | 457669307 |
| FOLD | AMICUS THERAPEUTICS INC | 8,145,311 | $86.99M | 11.3% | $10.68 | $9.63 | +13.1% | COM | 03152W109 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 1,090,056 | $76.62M | 10.0% | $70.29 * | $83.16 | +0.5% | COM | 09061G101 |
| UTHR | UNITED THERAPEUTICS CORP | 183,246 | $65.67M | 8.5% | $358.35 * | $89.23 | +278.5% | COM | 91307C102 |
| BIIB | BIOGEN INC | 228,916 | $44.37M | 5.8% | $193.84 * | $264.98 | -21.0% | COM | 09062X103 |
| STAA | STAAR SURGICAL CO | 1,091,608 | $40.55M | 5.3% | $37.15 | $24.23 | +53.9% | COM PAR $0.01 | 852312305 |
| ACAD | ACADIA PHARMACEUTICALS INC | 2,523,956 | $38.82M | 5.0% | $15.38 * | $27.92 | -40.3% | COM | 004225108 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 140,681 | $38.69M | 5.0% | $275.03 * | $260.36 | 0.0% | COM | 02043Q107 |
| PRTA | PROTHENA CORP PLC | 1,737,964 | $29.08M | 3.8% | $16.73 * | $21.46 | +0.2% | SHS | G72800108 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 3,041,685 | $28.56M | 3.7% | $9.39 | $6.52 | +45.3% | COM | 462260100 |
| ANAB | ANAPTYSBIO INC | 843,971 | $28.27M | 3.7% | $33.50 | $19.85 | +72.1% | COM | 032724106 |
| SRPT | SAREPTA THERAPEUTICS INC | 210,258 | $26.26M | 3.4% | $124.89 * | $112.41 | +23.0% | COM | 803607100 |
| ALKS | ALKERMES PLC | 384,656 | $10.77M | 1.4% | $27.99 * | $22.36 | +19.2% | SHS | G01767105 |
| PTCT | PTC THERAPEUTICS INC | 264,469 | $9.812M | 1.3% | $37.10 * | $33.48 | 0.0% | COM | 69366J200 |
| ALGN | ALIGN TECHNOLOGY INC | 37,772 | $9.606M | 1.2% | $254.32 * | $149.18 | +58.2% | COM | 016255101 |
| EHTH | EHEALTH INC | 2,347,519 | $9.578M | 1.2% | $4.08 * | $38.13 | -88.7% | COM | 28238P109 |
| NVCR | NOVOCURE LTD | 593,540 | $9.277M | 1.2% | $15.63 * | $56.67 | -68.0% | ORD SHS | G6674U108 |
| — | ACELYRIN INC | 1,792,895 | $8.839M | 1.1% | $4.93 | $6.67 | — | COM | 00445A100 |
| — | REVANCE THERAPEUTICS INC | 1,611,787 | $8.365M | 1.1% | $5.19 | $21.40 | — | COM | 761330109 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 405,193 | $7.8M | 1.0% | $19.25 * | $16.84 | +22.7% | COM | 87164F105 |
| — | SAGE THERAPEUTICS INC | 1,010,833 | $7.298M | 0.9% | $7.22 | $42.50 | — | COM | 78667J108 |
| GOSS | GOSSAMER BIO INC | 6,277,093 | $6.192M | 0.8% | $0.99 | $1.58 | -39.1% | COM | 38341P102 |
| — | KARYOPHARM THERAPEUTICS INC | 5,102,193 | $4.235M | 0.6% | $0.83 | $16.36 | — | COM | 48576U106 |
| — | NEVRO CORP | 750,371 | $4.195M | 0.5% | $5.59 | $21.87 | — | COM | 64157F103 |
| BNTX | BIONTECH SE-ADR | 25,206 | $2.994M | 0.4% | $118.77 | $118.77 | — | SPONSORED ADS | 09075V102 |
| — | VERVE THERAPEUTICS INC | 575,817 | $2.787M | 0.4% | $4.84 | $13.94 | — | COM | 92539P101 |
| EW | EDWARDS LIFESCIENCES CORP | 39,473 | $2.605M | 0.3% | $65.99 * | $72.66 | 0.0% | COM | 28176E108 |
| MIRM | MIRUM PHARMACEUTICALS INC | 64,700 | $2.523M | 0.3% | $39.00 * | $15.56 | +156.4% | COM | 604749101 |
| RLMD | RELMADA THERAPEUTICS INC | 732,400 | $2.373M | 0.3% | $3.24 | $3.27 | -1.0% | COM | 75955J402 |
| NUVB | NUVATION BIO INC | 772,652 | $1.769M | 0.2% | $2.29 * | $1.92 | +58.8% | COM CL A | 67080N101 |
| TSHA | TAYSHA GENE THERAPIES INC | 811,268 | $1.631M | 0.2% | $2.01 * | $2.02 | +8.4% | COM SHS | 877619106 |
| TVTX | TRAVERE THERAPEUTICS INC | 110,719 | $1.549M | 0.2% | $13.99 * | $23.56 | -55.8% | COM | 89422G107 |
| STOK | STOKE THERAPEUTICS INC | 125,861 | $1.547M | 0.2% | $12.29 * | $6.06 | +133.8% | COM | 86150R107 |
| BCYC | BICYCLE THERAPEUTICS PLC-ADR | 59,582 | $1.348M | 0.2% | $22.63 | $22.63 | — | SPONSORED ADS | 088786108 |
| HUM | HUMANA INC | 3,985 | $1.262M | 0.2% | $316.74 * | $369.63 | -5.6% | COM | 444859102 |
| ALDX | ALDEYRA THERAPEUTICS INC | 225,465 | $1.215M | 0.2% | $5.39 * | $5.95 | -20.0% | COM | 01438T106 |
| VYNE | VYNE THERAPEUTICS INC PIPE | 445,434 | $837K | 0.1% | $1.88 | $3.12 | -39.2% | COM | 92941V308 |
| — | ELEVATION ONCOLOGY INC | 1,298,097 | $779K | 0.1% | $0.60 | $4.52 | — | COM | 28623U101 |
| TIL | INSTIL BIO INC | 11,165 | $752K | 0.1% | $67.32 * | $23.54 | 0.0% | COM NEW | 45783C200 |
| ACRS | ACLARIS THERAPEUTICS INC | 569,832 | $655K | 0.1% | $1.15 * | $1.19 | +2.9% | COM | 00461U105 |
| PYXS | PYXIS ONCOLOGY INC | 170,000 | $624K | 0.1% | $3.67 * | $3.50 | 0.0% | COMMON STOCK | 747324101 |
| — | GENERATION BIO CO | 150,475 | $372K | 0.0% | $2.47 | $2.82 | — | COM | 37148K100 |
| — | BLUEBIRD BIO INC | 604,260 | $314K | 0.0% | $0.52 | $1.35 | — | COM | 09609G100 |
| URGN | UROGEN PHARMA LTD | 24,500 | $311K | 0.0% | $12.70 * | $27.01 | -45.1% | COM | M96088105 |
| ABEO | ABEONA THERAPEUTICS INC | 12,865 | $81,307 | 0.0% | $6.32 * | $5.22 | 0.0% | COM NEW | 00289Y206 |