Tri Locum Partners LP Quant / Systematic

CIK: 0001826434 · Show all filings

Period: Q4 2025 (← Previous)

Filing Date: Feb 17, 2026

Total Value ($000): $770,123 (100.0% shares, 0.0% debt)

Holdings (15)

New Positions (7)

DHR DANAHER CORPORATION 10.3%

Value ($000) $79,407 Shares 346,875 Est. Cost $219.54 Unrealized 0.0%

LLY ELI LILLY & CO 8.8%

Value ($000) $68,010 Shares 63,284 Est. Cost $955.55 Unrealized 0.0%

BSX BOSTON SCIENTIFIC CORP 6.4%

Value ($000) $49,630 Shares 520,508 Est. Cost $98.04 Unrealized 0.0%

TEVA TEVA PHARMACEUTICAL INDS LTD 5.8%

Value ($000) $44,813 Shares 1,435,865 Est. Cost $31.21 Unrealized —

IONS IONIS PHARMACEUTICALS INC 5.7%

Value ($000) $44,078 Shares 557,174 Est. Cost $75.30 Unrealized 0.0%

NUVL NUVALENT INC 4.0%

Value ($000) $30,918 Shares 307,371 Est. Cost $98.60 Unrealized 0.0%

DXCM DEXCOM INC 3.6%

Value ($000) $27,982 Shares 421,600 Est. Cost $64.65 Unrealized 0.0%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
DHR	DANAHER CORPORATION	346,875	$79,407	10.3%	$219.54	0.0%	COM	235851102
LLY	ELI LILLY & CO	63,284	$68,010	8.8%	$955.55	0.0%	COM	532457108
BSX	BOSTON SCIENTIFIC CORP	520,508	$49,630	6.4%	$98.04	0.0%	COM	101137107
TEVA	TEVA PHARMACEUTICAL INDS LTD	1,435,865	$44,813	5.8%	$31.21	—	SPONSORED ADS	881624209
IONS	IONIS PHARMACEUTICALS INC	557,174	$44,078	5.7%	$75.30	0.0%	COM	462222100
NUVL	NUVALENT INC	307,371	$30,918	4.0%	$98.60	0.0%	COM	670703107
DXCM	DEXCOM INC	421,600	$27,982	3.6%	$64.65	0.0%	COM	252131107

Increased Positions (4)

JNJ JOHNSON & JOHNSON 16.2%

Value ($000) $124,820 (+122.3%) Shares 603,143 (+99.2%) Est. Cost $183.20 Unrealized +7.5%

ASND ASCENDIS PHARMA A/S 7.3%

Value ($000) $56,512 (+62.6%) Shares 265,015 (+51.6%) Est. Cost $187.08 Unrealized —

MDGL MADRIGAL PHARMACEUTICALS INC 6.5%

Value ($000) $50,095 (+61.3%) Shares 86,023 (+27.1%) Est. Cost $319.67 Unrealized +59.8%

DNTH DIANTHUS THERAPEUTICS INC 3.3%

Value ($000) $25,649 (+256.4%) Shares 622,403 (+240.4%) Est. Cost $34.89 Unrealized +11.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
JNJ	JOHNSON & JOHNSON	603,143 (+99.2%)	$124,820 (+122.3%)	16.2%	$183.20	+7.5%	COM	478160104
ASND	ASCENDIS PHARMA A/S	265,015 (+51.6%)	$56,512 (+62.6%)	7.3%	$187.08	—	SPONSORED ADR	04351P101
MDGL	MADRIGAL PHARMACEUTICALS INC	86,023 (+27.1%)	$50,095 (+61.3%)	6.5%	$319.67	+59.8%	COM	558868105
DNTH	DIANTHUS THERAPEUTICS INC	622,403 (+240.4%)	$25,649 (+256.4%)	3.3%	$34.89	+11.1%	COM	252828108

Exited Positions (10)

MRK MERCK & CO INC 4.9%

Value ($000) $37,506 Shares 446,874 Est. Cost $81.01 Unrealized +15.1%

SLNO SOLENO THERAPEUTICS INC 4.0%

Value ($000) $30,460 Shares 450,585 Est. Cost $60.96 Unrealized -10.1%

ABBV ABBVIE INC 2.7%

Value ($000) $20,751 Shares 89,621 Est. Cost $189.97 Unrealized +19.8%

KRRO KORRO BIO INC 2.1%

Value ($000) $16,176 Shares 337,764 Est. Cost $33.68 Unrealized -30.6%

XENE XENON PHARMACEUTICALS INC 1.9%

Value ($000) $14,699 Shares 366,102 Est. Cost $35.22 Unrealized +19.2%

— AVADEL PHARMACEUTICALS PLC 1.4%

Value ($000) $11,069 Shares 724,859 Est. Cost $8.85 Unrealized —

STVN STEVANATO GROUP S P A 1.1%

Value ($000) $8,572 Shares 332,912 Est. Cost $24.68 Unrealized -5.9%

TARS TARSUS PHARMACEUTICALS INC 0.9%

Value ($000) $7,088 Shares 119,260 Est. Cost $45.00 Unrealized +65.9%

PRAX PRAXIS PRECISION MEDICINES I 0.5%

Value ($000) $4,027 Shares 75,986 Est. Cost $50.40 Unrealized +269.5%

BHVN BIOHAVEN LTD 0.3%

Value ($000) $2,239 Shares 149,179 Est. Cost $17.82 Unrealized -30.5%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
MRK	MERCK & CO INC	446,874	$37,506	4.9%	$81.01	+15.1%	—	58933Y105
SLNO	SOLENO THERAPEUTICS INC	450,585	$30,460	4.0%	$60.96	-10.1%	—	834203309
ABBV	ABBVIE INC	89,621	$20,751	2.7%	$189.97	+19.8%	—	00287Y109
KRRO	KORRO BIO INC	337,764	$16,176	2.1%	$33.68	-30.6%	—	500946108
XENE	XENON PHARMACEUTICALS INC	366,102	$14,699	1.9%	$35.22	+19.2%	—	98420N105
—	AVADEL PHARMACEUTICALS PLC	724,859	$11,069	1.4%	$8.85	—	—	G29687103
STVN	STEVANATO GROUP S P A	332,912	$8,572	1.1%	$24.68	-5.9%	—	T9224W109
TARS	TARSUS PHARMACEUTICALS INC	119,260	$7,088	0.9%	$45.00	+65.9%	—	87650L103
PRAX	PRAXIS PRECISION MEDICINES I	75,986	$4,027	0.5%	$50.40	+269.5%	—	74006W207
BHVN	BIOHAVEN LTD	149,179	$2,239	0.3%	$17.82	-30.5%	—	G1110E107

Decreased Positions (4)

UTHR UNITED THERAPEUTICS CORP DEL 7.7%

Value ($000) $58,919 (+15.0%) Shares 120,921 (-1.0%) Est. Cost $336.31 Unrealized +38.5%

VERA VERA THERAPEUTICS INC 5.3%

Value ($000) $40,800 (+18.0%) Shares 805,689 (-32.3%) Est. Cost $24.12 Unrealized +47.2%

AXSM AXSOME THERAPEUTICS INC 4.8%

Value ($000) $36,825 (+3.8%) Shares 201,627 (-31.0%) Est. Cost $101.43 Unrealized +37.6%

ARGX ARGENX SE 4.1%

Value ($000) $31,664 (-1.1%) Shares 37,653 (-13.3%) Est. Cost $507.27 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
UTHR	UNITED THERAPEUTICS CORP DEL	120,921 (-1.0%)	$58,919 (+15.0%)	7.7%	$336.31	+38.5%	COM	91307C102
VERA	VERA THERAPEUTICS INC	805,689 (-32.3%)	$40,800 (+18.0%)	5.3%	$24.12	+47.2%	CL A	92337R101
AXSM	AXSOME THERAPEUTICS INC	201,627 (-31.0%)	$36,825 (+3.8%)	4.8%	$101.43	+37.6%	COM	05464T104
ARGX	ARGENX SE	37,653 (-13.3%)	$31,664 (-1.1%)	4.1%	$507.27	—	SPONSORED ADR	04016X101